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Top Holiday Rentals in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, 115 reviews
"Nice comfortable accomodations very clean. The kitchen had everything you needed. Easy area to get around the Saturday Farmers market down the street was nice"
The price is £195
per night
22 Jun - 23 Jun
Serenity South -- Gardens, River-Views, and Refreshing Space
Charming 2-Story- C.1847 - River Views - Fast Wifi
9.8 out of 10, Exceptional, 11 reviews
"We had a delightful stay in this charming house. It was roomy and had most everything we needed for a comfortable stay. It was fun to have a view of the Mississippi."
Charming 2-Story- C.1847 - River Views - Fast Wifi
Little Blue Cottage on Spanish
8.8 out of 10, Excellent, 32 reviews
"We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect"
The price is £71
per night
17 Jun - 18 Jun
Little Blue Cottage on Spanish
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Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.8 out of 10, Exceptional, 21 reviews
"This place was fantastic. Location was near all we wanted to do."
The price is £119
per night
16 Jun - 17 Jun
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
River Town Retreat near SEMO
10.0 out of 10, Exceptional, 1 review
"Very nice place only downsize albeit cute is the claw foot tub with make shift shower, The unit worked very well for what we were looking for near SEMO campus"
River Town Retreat near SEMO
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
9.0 out of 10, Wonderful, 2 reviews
"First, the owner and their communication was fantastic. The space was exactly as described, comfortable and clean. The proximity to everything from the river, to downtown and even to the great restaurants on upper Broadway is walkable and great. The “but” is that we stayed Friday and Saturday and it is located right on Broadway (popular cruising street) next to a popular bar that itself is loud and fills the parking area out back with partying till near 2 am. Truly, otherwise, a great stay."
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Quaint, Beautiful Home next to SEMO and Hospital
9.8 out of 10, Exceptional, 19 reviews
"Clean, quiet and close to what we needed. Great overall experience"
Quaint, Beautiful Home next to SEMO and Hospital
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
9.2 out of 10, Wonderful, 20 reviews
"This property was perfect for our family and our 4 boys really enjoyed the mini golf, pool table, couch swing and signing the wall. We will definitely be coming back on our travels. Unique decor and beautiful space! "
The price is £309
per night
25 Jun - 26 Jun
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
Charming Secluded Getaway Cabin within minutes of amenities
10.0 out of 10, Exceptional, 9 reviews
"This place is amazing if what you want is relaxing. My wife and I stayed here for the total eclipse and did not see another person for our whole stay. This place sets the standard for secluded. The cabin had everything you could need for a great stay. Price was very reasonable. We could not be happier. "
Charming Secluded Getaway Cabin within minutes of amenities
The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, 8 reviews
"Extremely happy with our stay! Everything was perfect and even better than we expected! We have done about a dozen VRBO and ABnB stays and this was the cleanest stay we have ever had. The outdoor bed was wonderful and the location was good. It was close to town yet couldn't see any other houses from the deck or the outdoor bed in the backyard. There was a nice firepit and hot tub, (however we didn't use them). Very fast message replys when I had a question for the hosts. This was a great stay to...
The price is £273
per night
8 Jul - 9 Jul
The Twisted Sassafras Treehouse
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, 202 reviews
"beautiful place. great location. recommend to anyone"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
10.0 out of 10, Exceptional, 3 reviews
"Gorgeous home with unique finishings and a lot of attention to detail. A very quick trip did not allow for relaxing on the back screened in porch. "
"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
Steps to Southeast Hospital - Fast Wifi - King Bed
10.0 out of 10, Exceptional, 2 reviews
"The house was perfect for our group. It was in a great location and was exactly as advertised. I would definitely stay here again!"
The price is £306
per night
16 Jun - 17 Jun
Steps to Southeast Hospital - Fast Wifi - King Bed
Luxury Loft Gallery next to Southeast Missouri State River Campus in Downtown CG
10.0 out of 10, Exceptional, 2 reviews
"The property is beautifully designed for comfort and relaxation. The space beckons you to pause, rest, and enjoy your time away. They even remembered the small details to ensure your stay goes smoothly. Check in process was seamless and we had all the information we needed. I would highly recommend for your next visit to the area or weekend retreat!"
Luxury Loft Gallery next to Southeast Missouri State River Campus in Downtown CG
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi
10.0 out of 10, Exceptional, 4 reviews
"This was a great place for us to stay while in town for a family emergency. We will be staying here again the next time we visit. Great communication, comfortable beds, clean and fully stocked with supplies."
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi
New cabin in the woods with private hot tub
10.0 out of 10, Exceptional, 76 reviews
"Met all our expectations. Smart finish, easy to find, great hot tub. Comfortable and relaxing. We enjoyed exploring and sampling the Shawnee Wine Trail."
New cabin in the woods with private hot tub
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, 340 reviews
"Clean, hospitable and relaxing. Hope to return!"
The price is £155
per night
16 Jun - 17 Jun
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
10.0 out of 10, Exceptional, 83 reviews
"Adorable modern cabin in a very secluded area on the Wine Trail. We had a great time - the hot tub was so relaxing after a day at the a wineries. Loved watching the cows and the bull at the neighboring property, and we even saw deer on Sunday morning. Will definitely book again!"
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Rated#1 Big Sky Cabin! 🍷 On the Wine Trail Hot Tub 🔥 FirePit Pool 🎱 Table
10.0 out of 10, Exceptional, 147 reviews
"We really enjoyed the property & having a fun oasis! The host was very helpful and communicable with my partner & I! Thank you for everything!!"
Rated#1 Big Sky Cabin! 🍷 On the Wine Trail Hot Tub 🔥 FirePit Pool 🎱 Table
Minutes from Giant City - SIU - Shawnee Winetrail - Cedar Lake - Shawnee Forest!
9.4 out of 10, Exceptional, 20 reviews
"Everything was perfect it was just what i needed and anytime i needed anything steve was ready to help. Very peaceful and quite."
Minutes from Giant City - SIU - Shawnee Winetrail - Cedar Lake - Shawnee Forest!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Holiday Rental Travel Info

Other types of properties in Cape Girardeau you may be interested in

Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, 1,003 reviews
"Very impressed with this hotel, I will be staying again."
The price is £66
per night
16 Jun - 17 Jun
Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, 1,002 reviews
"When traveling with dogs 🐕 we have to accept the upcharges! 2 dogs $50 a night ouch! Its a clean comfortable room. 2nd floor and tge elevator isnt working. Oh well!"
The price is £57
per night
23 Jun - 24 Jun
Pear Tree Inn Cape Girardeau West
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, 1,006 reviews
"Good for a night!"
The price is £99
per night
19 Jun - 20 Jun
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Cape Girardeau holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Cape Girardeau holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cape Girardeau holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Cape Girardeau holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Cape Girardeau. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Cape Girardeau holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Cape Girardeau holiday rentals we have selected for you start as low as £71 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Cape Girardeau rentals

At Expedia, we put the best Cape Girardeau holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Cape Girardeau rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cape Girardeau holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cape Girardeau. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find holiday rentals in Cape Girardeau?

Yes, there are holiday rentals in Cape Girardeau close to Cape Splash Family Aquatic Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your holiday.

What are some of the best holiday rentals that Cape Girardeau has to offer?

Serenity South -- Gardens, River-Views, and Refreshing Space: This highly rated holiday home rental in Cape Girardeau is located on a river, and has a fireplace, a balcony and air conditioning to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include Little Blue Cottage on Spanish and Charming 2-Story- C.1847 - River Views - Fast Wifi.

How many holiday rentals will I find in Cape Girardeau?

Choose from 23 Expedia holiday rentals in Cape Girardeau for a memorable holiday.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Riverfront Bridge Park and Trail of Tears State Park are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are holiday rentals like in Cape Girardeau?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Cape Girardeau. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a holiday rental can provide a sense of security away from public hotel lifts and busy front desks while still allowing you the experience of travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is an attractive choice for a small group gathering.

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