Eastern Panama Mountain Holidays

Book a Mountain Hotel + Flight or Car together to unlock savings

Photo by Nico Barner

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Top flight + Mountain hotel deals in Eastern Panama

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Tocumen Airport
£456
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.6/10 Excellent! (1,811 reviews)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
£568
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.4/10 Very good! (1,693 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
£576
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Muy buena atención

Reviewed on 19 Sept 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
£522
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9.6/10 Exceptional! (438 reviews)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
£984
per person
19 Oct - 25 Oct
found 21 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
8.6/10 Excellent! (1,708 reviews)
Location is wonderful.

Reviewed on 19 Sept 2026

Don't see what you're looking for?
See all available trips from Medellín to Eastern Panama
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5* Mountain holidays in Eastern Panama

Price found within the past 48 hours. Click for updated prices.
Renaissance Panama City Hotel

Renaissance Panama City Hotel

Bella Vista
£459
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.8/10 Excellent! (292 reviews)
Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
£522
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9.6/10 Exceptional! (438 reviews)
W Panama

W Panama

Bella Vista
£760
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (1,003 reviews)
Don't see what you're looking for?
See all available trips from Medellín to Eastern Panama
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4 Night Mountain holidays in Eastern Panama

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Tocumen Airport
£456
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.6/10 Excellent! (1,811 reviews)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
£568
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.4/10 Very good! (1,693 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
£576
per person
2 Dec - 6 Dec
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Muy buena atención

Reviewed on 19 Sept 2026

Don't see what you're looking for?
See all available trips from Medellín to Eastern Panama
View all trips

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.