A seal swimming in clear water.
Photo by Elizabeth Oates
Open Photo by Elizabeth Oates

Santa Fe Island Adults Only Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Top Adults Only holiday packages in Santa Fe Island

Price found within the past 48 hours. Click for updated prices.
  • 4 Jan - 11 Jan

    Galapagos Native + Flight

    Puerto Ayora
    6 nights
    3.0 star property
    7.8/10 - Good (101 reviews)
    "Do not book this hotel. There was zero hot water on any of the days, and on our last day there was no water at all. Took over an hour first morning to get our breakfast (eggs and toast) which came out cold. Weak lukewarm instant coffee! Second morning no better, we asked for hot water to use our own Starbucks instant coffee, and again, only lukewarm."
    Reviewed October 1, 2026
    Return • London (LHR) - Santa Cruz Island (GPS)
    LHR - GPS • 2 stops GPS - LHR • 2 stops
    £1,886
    £1,649
    per traveller
    found 1 day ago
    Galapagos Native
  • 4 Jan - 11 Jan

    Angermeyer Waterfront Inn + Flight

    Puerto Ayora
    6 nights
    3.5 star property
    9.4/10 - Exceptional (151 reviews)
    "Great staff, great location."
    Reviewed October 22, 2026
    Return • London (LHR) - Santa Cruz Island (GPS)
    LHR - GPS • 2 stops GPS - LHR • 2 stops
    £2,682
    £2,254
    per traveller
    found 1 day ago
    Angermeyer Waterfront Inn
  • 4 Jan - 11 Jan

    Galapagos Sea Star + Flight

    Puerto Ayora
    6 nights
    2.0 star property
    Return • London (LHR) - Santa Cruz Island (GPS)
    LHR - GPS • 2 stops GPS - LHR • 2 stops
    £5,076
    £4,338
    per traveller
    found 1 day ago
    Galapagos Sea Star
  • 4 Jan - 11 Jan

    Hotel Albemarle Galapagos Beachfront + Flight

    Puerto Villamil
    6 nights
    3.5 star property
    9.0/10 - Wonderful (115 reviews)
    "Samey was wonderful and she helped me to sign up for day trips ahead of our visit and she recommended some great restaurants for some delicious meals. Our room on the second floor had a direct ocean view and the hotel had a really good location,a short walk from the ferry. The Hotel Albemarle Galapagos Beachfront is a great hotel."
    Reviewed October 26, 2026
    Return • London (LHR) - Santa Cruz Island (GPS)
    LHR - GPS • 2 stops GPS - LHR • 2 stops
    £2,299
    £1,994
    per traveller
    found 1 day ago
    Hotel Albemarle Galapagos Beachfront
  • 4 Jan - 11 Jan

    Hotel Galapagos Tortuga Bay + Flight

    Bella Vista
    6 nights
    2.0 star property
    7.6/10 - Good (5 reviews)
    Return • London (LHR) - Santa Cruz Island (GPS)
    LHR - GPS • 2 stops GPS - LHR • 2 stops
    £1,912
    £1,741
    per traveller
    found 1 day ago
    Hotel Galapagos Tortuga Bay

Frequently Asked Questions

Why should I book my Santa Fe Island holiday with Expedia?

Expedia has you covered for every detail of your upcoming Santa Fe Island holiday. You'll always get the best prices, but when you bundle your accommodation, flights and/or car hire into a holiday package, you'll score even more savings. Want to truly make the most of your escape? Add some activities and tours to your customised package. Expedia offers flexible cancellation policies on almost all bookings, so you won't need to stress if you have to change your plans. Head over to our Customer Service Portal link to discover more.

How do I get a cheap holiday to Santa Fe Island?

Booking a Santa Fe Island holiday with Expedia is the easiest way to save. We have access to more than 400 air carriers and 321,000 hotels globally. With such an extensive range to select from, you'll have no issues putting together your ideal holiday. Learn more about how you can save money on your next holiday when you combine your flight and hotel bookings with Expedia.

Do I need a visa for my Santa Fe Island holiday?

Research the latest information on official government websites. Your nationality and whether you're travelling for leisure, study or business will determine if you'll need a visa for Santa Fe Island. Make yourself familiar with the application process, including any required documentation, turnaround times and fees. Start your application well in advance to allow plenty of time for processing. Some visas may take weeks or even months to obtain, depending on the country.

What should I wear on my Santa Fe Island holiday?

Though everyone's personal style is different, it can help to have a few guidelines for what type of clothes to wear on your holiday in Santa Fe Island. Consider browsing style blogs before you head off for inspiration on local fashion trends.

What does an Expedia Santa Fe Island holiday include?

Select from a combination of hire cars, flights and hotels. Once you've made your booking, add some tours and activities. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to organising your perfect Santa Fe Island trip. Enjoy the flexibility and freedom to tailor your dream escape with Expedia.

Does Expedia offer Book Now, Pay Later Santa Fe Island holidays?

Good news! We do. Expedia has joined forces with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply pick the payment plan that suits you best during checkout and take the stress out of budgeting for your next trip. Don't forget to bundle your accommodation, flights and activities with Expedia to get the biggest bang for your travel buck. Browse our flexible payment options below:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's manageable payment plans. If paying across multiple transactions sounds right for you, pick this option at checkout.
  • No-deposit holidays: Pressing the "book now" button is easier with this payment plan. With no deposit required for your holiday, you can Book Now, Pay Later and start packing your bags.

Can I choose my airline with a Santa Fe Island Expedia holiday?

You can. We have more than 400 partner airlines around the world, so choose the carrier that fits your budget and travel needs.