£511 Cheap Flights from Panama City (PTY) to Frankfurt (FRA)

View £511 flight on Wed, 25 Nov 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Frankfurt Airport (FRA)

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Cheap Flights from Panama City (PTY) to Frankfurt (FRA)

Prices were available within the past 7 days and start at £511 for one-way flights and £782 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, 18 Aug - Mon, 14 Sept
PTY
Panama City
FRA
Frankfurt
£782 Return, found 1 day ago
£782
Return
found 1 day ago
Select United flight, departing Tue, 18 Aug from Panama City to Frankfurt, returning Mon, 14 Sept, priced at £782 found 1 day ago
KLM
Tue, 10 Nov - Sun, 15 Nov
PTY
Panama City
FRA
Frankfurt
£810 Return, found 2 days ago
£810
Return
found 2 days ago
Select KLM flight, departing Tue, 10 Nov from Panama City to Frankfurt, returning Sun, 15 Nov, priced at £810 found 2 days ago
Air Europa
Tue, 10 Nov - Fri, 20 Nov
PTY
Panama City
FRA
Frankfurt
£814 Return, found 6 days ago
£814
Return
found 6 days ago
Select Air Europa flight, departing Tue, 10 Nov from Panama City to Frankfurt, returning Fri, 20 Nov, priced at £814 found 6 days ago
Turkish Airlines
Mon, 7 Dec - Fri, 8 Jan
PTY
Panama City
FRA
Frankfurt
£817 Return, found 6 days ago
£817
Return
found 6 days ago
Select Turkish Airlines flight, departing Mon, 7 Dec from Panama City to Frankfurt, returning Fri, 8 Jan, priced at £817 found 6 days ago
Air France
Tue, 10 Nov - Sun, 15 Nov
PTY
Panama City
FRA
Frankfurt
£818 Return, found 2 days ago
£818
Return
found 2 days ago
Select Air France flight, departing Tue, 10 Nov from Panama City to Frankfurt, returning Sun, 15 Nov, priced at £818 found 2 days ago
Air Europa
Tue, 10 Nov - Fri, 20 Nov
PTY
Panama City
FRA
Frankfurt
£822 Return, found 6 days ago
£822
Return
found 6 days ago
Select Air Europa flight, departing Tue, 10 Nov from Panama City to Frankfurt, returning Fri, 20 Nov, priced at £822 found 6 days ago
avianca
Tue, 10 Nov - Fri, 20 Nov
PTY
Panama City
FRA
Frankfurt
£828 Return, found 6 days ago
£828
Return
found 6 days ago
Select avianca flight, departing Tue, 10 Nov from Panama City to Frankfurt, returning Fri, 20 Nov, priced at £828 found 6 days ago
Iberia
Mon, 3 Aug - Mon, 14 Sept
PTY
Panama City
FRA
Frankfurt
£830 Return, found 6 days ago
£830
Return
found 6 days ago
Select Iberia flight, departing Mon, 3 Aug from Panama City to Frankfurt, returning Mon, 14 Sept, priced at £830 found 6 days ago
avianca
Tue, 10 Nov - Fri, 20 Nov
PTY
Panama City
FRA
Frankfurt
£834 Return, found 6 days ago
£834
Return
found 6 days ago
Select avianca flight, departing Tue, 10 Nov from Panama City to Frankfurt, returning Fri, 20 Nov, priced at £834 found 6 days ago
Lufthansa
Fri, 4 Dec - Tue, 5 Jan
PTY
Panama City
FRA
Frankfurt
£835 Return, found 6 days ago
£835
Return
found 6 days ago
Select Lufthansa flight, departing Fri, 4 Dec from Panama City to Frankfurt, returning Tue, 5 Jan, priced at £835 found 6 days ago

Frequently asked questions

Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
Enter PTY to FRA and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
The best airline to fly with from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) will differ from traveller to traveller. If you like to fly early, DE offers early morning flights. If price is the most important factor, DE typically offers the lowest fares. AV offers the most daily flights from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
There are approximately 43 connecting flights per day from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.). Some common connection points include El Dorado Intl. (BOG), Liberty Intl. (EWR), and Washington Dulles Intl. (IAD).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) typically departs at approximately 2:55 AM local time. This seasonal service is active in November and is operated by Avianca and Iberia. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
You'll typically find the most flights from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) on a Friday, with around 41 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Copa Airlines, Avianca, and United Airlines. Compared to other days, Friday offers notably more flight options.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) are in the morning, from 9am to 12pm. About 35% of passengers prefer this time. Many major carriers, including Copa Airlines, Lufthansa and United Airlines, offer flights during this window. This timing works well because it allows you to start your travel day at a reasonable hour and arrive at your destination with plenty of time to settle in.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
Direct flights from PTY to FRA usually take about 11 hours 20 minutes, traveling roughly 5,649 miles. If you opt for a connecting flight, expect to add around 6 hours to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
Select the "Business class" and "First class" filters when looking for PTY to FRA flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Frankfurt from Tocumen Intl. (PTY)?
From Tocumen Intl. (PTY), you can fly into Frankfurt Intl. (FRA) to reach Frankfurt. Some flights may connect through major hubs like El Dorado Intl. (BOG), Liberty Intl. (EWR), Miami Intl. (MIA) before reaching Frankfurt. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.)?
If you booked your Panama City (PTY-Tocumen Intl.) to Frankfurt (FRA-Frankfurt Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Frankfurt Intl.
Airlines serving
Air Europa, Air France, Delta, Iberia, KLM, Turkish Airlines, United
Return price
£781
Distance
9037 km

Book with confidence

Compare flights from Panama City to Frankfurt easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Frankfurt. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Frankfurt Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to Frankfurt Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Tocumen Intl. (PTY) to Frankfurt Intl. (FRA)

The easiest way to view the best deals on flights from Panama City to Frankfurt today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to Frankfurt Intl. start at just £782 and range up to £835.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Panama City and Frankfurt
  • booking your flight during August, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Panama City to Frankfurt flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to Frankfurt Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Panama City to Frankfurt easily and book with confidence

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*Available to Expedia members.