£161 Cheap Flights from Panama City (PTY) to Cancun (CUN)

View £161 flight on Fri, 21 Aug 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Cancun Intl. Airport (CUN)

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Cheap Flights from Panama City (PTY) to Cancun (CUN)

Prices were available within the past 7 days and start at £161 for one-way flights and £249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Thu, 25 Jun - Mon, 29 Jun
PTY
Panama City
CUN
Cancun
£249 Return, found 6 days ago
£249
Return
found 6 days ago
Select Aeromexico flight, departing Thu, 25 Jun from Panama City to Cancun, returning Mon, 29 Jun, priced at £249 found 6 days ago
Aeromexico
Thu, 18 Jun - Sat, 20 Jun
PTY
Panama City
CUN
Cancun
£249 Return, found 5 hours ago
£249
Return
found 5 hours ago
Select Aeromexico flight, departing Thu, 18 Jun from Panama City to Cancun, returning Sat, 20 Jun, priced at £249 found 5 hours ago
Aeromexico
Mon, 9 Nov - Mon, 23 Nov
PTY
Panama City
CUN
Cancun
£250 Return, found 2 days ago
£250
Return
found 2 days ago
Select Aeromexico flight, departing Mon, 9 Nov from Panama City to Cancun, returning Mon, 23 Nov, priced at £250 found 2 days ago
Aeromexico
Thu, 18 Jun - Sun, 21 Jun
PTY
Panama City
CUN
Cancun
£253 Return, found 6 days ago
£253
Return
found 6 days ago
Select Aeromexico flight, departing Thu, 18 Jun from Panama City to Cancun, returning Sun, 21 Jun, priced at £253 found 6 days ago
Aeromexico
Thu, 25 Jun - Mon, 29 Jun
PTY
Panama City
CUN
Cancun
£254 Return, found 6 days ago
£254
Return
found 6 days ago
Select Aeromexico flight, departing Thu, 25 Jun from Panama City to Cancun, returning Mon, 29 Jun, priced at £254 found 6 days ago
Aeromexico
Thu, 5 Nov - Sun, 8 Nov
PTY
Panama City
CUN
Cancun
£256 Return, found 4 days ago
£256
Return
found 4 days ago
Select Aeromexico flight, departing Thu, 5 Nov from Panama City to Cancun, returning Sun, 8 Nov, priced at £256 found 4 days ago
avianca
Fri, 7 Aug - Sun, 16 Aug
PTY
Panama City
CUN
Cancun
£276 Return, found 5 days ago
£276
Return
found 5 days ago
Select avianca flight, departing Fri, 7 Aug from Panama City to Cancun, returning Sun, 16 Aug, priced at £276 found 5 days ago
Copa
Sat, 6 Jun - Fri, 19 Jun
PTY
Panama City
CUN
Cancun
£287 Return, found 6 days ago
£287
Return
found 6 days ago
Select Copa flight, departing Sat, 6 Jun from Panama City to Cancun, returning Fri, 19 Jun, priced at £287 found 6 days ago
American Airlines
Sat, 5 Sept - Fri, 11 Sept
PTY
Panama City
CUN
Cancun
£674 Return, found 3 days ago
£674
Return
found 3 days ago
Select American Airlines flight, departing Sat, 5 Sept from Panama City to Cancun, returning Fri, 11 Sept, priced at £674 found 3 days ago
United
Sat, 5 Sept - Fri, 11 Sept
PTY
Panama City
CUN
Cancun
£997 Return, found 3 days ago
£997
Return
found 3 days ago
Select United flight, departing Sat, 5 Sept from Panama City to Cancun, returning Fri, 11 Sept, priced at £997 found 3 days ago

Find the cheapest month to fly from Panama City (PTY) to Cancun (CUN)

October is typically the cheapest month to fly

From £248 - £251 per traveller.

Frequently asked questions

How much does a flight from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) cost?
One-way flights typically cost between $654 and $2,830 and return flights often range between $950 and $5,023. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
Enter PTY to CUN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
The best airline to fly with from Panama City (PTY-Tocumen Intl.) (PTY) to Cancun, Quintana Roo (CUN-Cancun Intl.) (CUN) will differ from traveler to traveler. If you like to fly early, CM offers early morning flights. If price is the most important factor, CM typically offers the lowest fares. AV offers the most daily flights from Panama City (PTY-Tocumen Intl.) (PTY) to Cancun, Quintana Roo (CUN-Cancun Intl.) (CUN), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
When flying from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.), you'll find approximately 6 nonstop flights per day. For even more choice, look at flights that include layovers, as there are around 28 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), Liberty Intl. (EWR), and George Bush Intercontinental (IAH).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) typically departs at approximately 2:55 AM local time. This flight is operated by AV and is a seasonal service, active in January, February, March, October, November, and December. An early departure like this can help you maximize your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
You'll find the most flights from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) on a Saturday, with around 25 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Copa, Avianca, and United Airlines. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) are in the early morning, from 6am to 9am. About 30% of passengers prefer this time window. Many major carriers, including Copa Airlines and United Airlines, offer flights during this window. These times work well because you can get an early start to your travel day and arrive in Cancun with plenty of time to enjoy your destination.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
A nonstop flight from PTY to CUN typically takes around 2 hours 50 minutes, covering approximately 966 miles. Connecting flights on this route usually add 20 hours 40 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
Select the "Business class" and "First class" filters when looking for PTY to CUN flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Cancun from Tocumen Intl. (PTY)?
If you're planning to travel to Cancun from Tocumen Intl. (PTY), you can fly into Cancun Intl. (CUN) Some flights may connect through major hubs like Juan Santamaria Intl. (SJO), El Dorado Intl. (BOG), Liberty Intl. (EWR) before reaching Cancun. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.)?
If you booked your Panama City (PTY-Tocumen Intl.) to Cancun, Quintana Roo (CUN-Cancun Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Cancun Intl.
Return price
£248
Distance
1545 km
Average flight time
2 hours 51 mins

Book with confidence

Compare flights from Panama City to Cancun easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Cancun. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Cancun Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to Cancun Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Tocumen Intl. (PTY) to Cancun Intl. (CUN)

The easiest way to view the best deals on flights from Panama City to Cancun today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to Cancun Intl. start at just £249 and range up to £997.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Panama City and Cancun
  • booking your flight during June, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Panama City to Cancun flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to Cancun Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Panama City to Cancun easily and book with confidence

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*Available to Expedia members.