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£327 Cheap Flights from Prague (PRG) to San Francisco (SFO)

View £327 flight on Tue, 22 Sept 2026Opens in a new window

Popular airlines from Vaclav Havel Airport (PRG) to San Francisco International Airport (SFO)

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Cheap Flights from Prague (PRG) to San Francisco (SFO)

Prices were available within the past 7 days and start at £327 for one-way flights and £410 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Thu, 1 Oct - Sun, 4 Oct
PRG
Prague
SFO
San Francisco
£410 Return, found 2 days ago
£410
Return
found 2 days ago
Select Lufthansa flight, departing Thu, 1 Oct from Prague to San Francisco, returning Sun, 4 Oct, priced at £410 found 2 days ago
United
Wed, 23 Sept - Tue, 29 Sept
PRG
Prague
SFO
San Francisco
£413 Return, found 1 day ago
£413
Return
found 1 day ago
Select United flight, departing Wed, 23 Sept from Prague to San Francisco, returning Tue, 29 Sept, priced at £413 found 1 day ago
Lufthansa
Thu, 1 Oct - Sun, 4 Oct
PRG
Prague
SFO
San Francisco
£413 Return, found 2 days ago
£413
Return
found 2 days ago
Select Lufthansa flight, departing Thu, 1 Oct from Prague to San Francisco, returning Sun, 4 Oct, priced at £413 found 2 days ago
Air Canada
Thu, 8 Oct - Sat, 17 Oct
PRG
Prague
SFO
San Francisco
£414 Return, found 1 day ago
£414
Return
found 1 day ago
Select Air Canada flight, departing Thu, 8 Oct from Prague to San Francisco, returning Sat, 17 Oct, priced at £414 found 1 day ago
British Airways
Wed, 23 Sept - Tue, 29 Sept
PRG
Prague
SFO
San Francisco
£414 Return, found 1 day ago
£414
Return
found 1 day ago
Select British Airways flight, departing Wed, 23 Sept from Prague to San Francisco, returning Tue, 29 Sept, priced at £414 found 1 day ago
Swiss International Air Lines
Tue, 18 Aug - Wed, 2 Sept
PRG
Prague
SFO
San Francisco
£416 Return, found 2 days ago
£416
Return
found 2 days ago
Select Swiss International Air Lines flight, departing Tue, 18 Aug from Prague to San Francisco, returning Wed, 2 Sept, priced at £416 found 2 days ago
Finnair
Wed, 23 Sept - Tue, 29 Sept
PRG
Prague
SFO
San Francisco
£417 Return, found 1 day ago
£417
Return
found 1 day ago
Select Finnair flight, departing Wed, 23 Sept from Prague to San Francisco, returning Tue, 29 Sept, priced at £417 found 1 day ago
American Airlines
Wed, 23 Sept - Tue, 29 Sept
PRG
Prague
SFO
San Francisco
£420 Return, found 1 day ago
£420
Return
found 1 day ago
Select American Airlines flight, departing Wed, 23 Sept from Prague to San Francisco, returning Tue, 29 Sept, priced at £420 found 1 day ago
LOT-Polish Airlines
Thu, 24 Sept - Thu, 1 Oct
PRG
Prague
SFO
San Francisco
£430 Return, found 1 hour ago
£430
Return
found 1 hour ago
Select LOT-Polish Airlines flight, departing Thu, 24 Sept from Prague to San Francisco, returning Thu, 1 Oct, priced at £430 found 1 hour ago
Brussels Airlines
Wed, 23 Sept - Tue, 29 Sept
PRG
Prague
SFO
San Francisco
£446 Return, found 1 day ago
£446
Return
found 1 day ago
Select Brussels Airlines flight, departing Wed, 23 Sept from Prague to San Francisco, returning Tue, 29 Sept, priced at £446 found 1 day ago

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to San Francisco Intl. SFO. Cheapest and Closest option available. Average driving time to city centre is 19 minutes. Flights from £677
SFO
San Francisco Intl.
CheapestClosest
Average driving time to city centre19 min
Flights from £677

Find the cheapest month to fly from Prague (PRG) to San Francisco (SFO)

May is typically the cheapest month to fly

From £382 - £524 per traveller.

Frequently asked questions

How much does a flight from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) cost?
You can find one-way and return flights from PRG to SFO with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when PRG to SFO ticket fares go up or down.
What is the cheapest month to fly from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
The cheapest months to fly from PRG to SFO are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
Enter PRG to SFO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
Lufthansa is one of the cheapest airlines offering connecting return flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.), with prices starting from around £445 for flights that can be booked for departure within the next year. These prices are per adult, for economy/coach class. Lufthansa flights typically include a layover in Franz Josef Strauss Intl. (MUC). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
To find a cheap flight from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
There are approximately 75 connecting flights per day from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.). Some common connection points include Frankfurt Intl. (FRA), Dublin (DUB), and Heathrow (LHR).
What is the earliest flight from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
The earliest flight from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) typically departs around 6:00 AM local time. This service is operated by British Airways and American Airlines. This is a seasonal service active in December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
You'll typically find the most flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) on a Wednesday, with around 52 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Lufthansa, British Airways, and Swiss International Air Lines. Flight schedules are consistent throughout the week, so you'll have plenty of options regardless of your travel day.
What are the most popular departure times for flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
The most popular departure times for flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) are between 9am and 12pm. Many major carriers, including Lufthansa, Swiss International Air Lines and British Airways, offer flights during this window. Many travellers prefer this time as it allows for a relaxed start to the day before a long-haul flight.
How long does it take to fly from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
There are no nonstop flights from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.). The shortest flights typically involve one stop, taking around 15 hours 18 minutes. If you opt for flights with two or more stops, your journey will be longer, usually around 21 hours 18 minutes. The total distance covered on this route is approximately 9,378 kilometers. Keep in mind that actual travel times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
You can fly business class or first class between PRG and SFO. Airlines that offer business class service on this route include:
  • Lufthansa
  • Air France
  • Iberia
  • Swiss International Air Lines
  • TAP Portugal
  • SAS
  • Brussels Airlines
  • KLM
  • Turkish Airlines
  • Emirates
  • Edelweiss Air
  • British Airways
  • Lufthansa Cityline
  • flydubai
  • Air Dolomiti
  • Icelandair
  • LOT-Polish Airlines
  • Air Canada
  • Caribbean Sun
  • Delta
  • Austrian Airlines
  • Finnair
  • Braathens Regional Aviation
  • Cityjet
  • American Airlines
  • Condor
  • Helvetic Airways
First class cabins are available on Emirates.
How do I earn miles on a Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) flight with Expedia?
It's easy to earn miles on a Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Francisco, CA (SFO) from Prague (PRG)?
If you're planning to travel to San Francisco from Vaclav Havel (PRG), you can fly directly into San Francisco Intl. (SFO). Some flights may connect through major hubs like Heathrow (LHR), Frankfurt Intl. (FRA), or Franz Josef Strauss Intl. (MUC) before reaching San Francisco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) at the last minute?
Typically, booking a last minute flight from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package?
Securing a Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.)?
If you booked your Prague (PRG-Vaclav Havel) to San Francisco, CA (SFO-San Francisco Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Vaclav Havel
Destination airport
San Francisco Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Condor, Delta, Finnair, Iberia, KLM, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Turkish Airlines, United
Return price
£410
Distance
9321 km

Book with confidence

Compare flights from Prague to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Prague to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Vaclav Havel to San Francisco Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Vaclav Havel (PRG) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Prague to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Vaclav Havel to San Francisco Intl. start at just £410 and range up to £565.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Prague and San Francisco
  • booking your flight during October, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Prague to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Vaclav Havel to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Prague to San Francisco easily and book with confidence

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*Available to Expedia members.