£177 Cheap Flights from Medellín (MDE) to Guayaquil (GYE)

View £177 flight on Thu, 11 Jun 2026Opens in a new window

Flight 1

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Jose Joaquin de Olmedo Intl. Airport (GYE)

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Cheap Flights from Medellín (MDE) to Guayaquil (GYE)

Prices were available within the past 7 days and start at £177 for one-way flights and £327 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, 14 Jul - Sun, 19 Jul
MDE
Medellín
GYE
Guayaquil
£327 Return, found 4 days ago
£327
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Tue, 14 Jul from Medellín to Guayaquil, returning Sun, 19 Jul, priced at £327 found 4 days ago
LATAM Airlines Group
Tue, 5 May - Mon, 25 May
MDE
Medellín
GYE
Guayaquil
£327 Return, found 2 days ago
£327
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 5 May from Medellín to Guayaquil, returning Mon, 25 May, priced at £327 found 2 days ago
Copa
Wed, 13 May - Fri, 15 May
MDE
Medellín
GYE
Guayaquil
£330 Return, found 1 day ago
£330
Return
found 1 day ago
Select Copa flight, departing Wed, 13 May from Medellín to Guayaquil, returning Fri, 15 May, priced at £330 found 1 day ago
Copa
Wed, 20 May - Wed, 27 May
MDE
Medellín
GYE
Guayaquil
£331 Return, found 4 days ago
£331
Return
found 4 days ago
Select Copa flight, departing Wed, 20 May from Medellín to Guayaquil, returning Wed, 27 May, priced at £331 found 4 days ago
Copa
Wed, 13 May - Fri, 15 May
MDE
Medellín
GYE
Guayaquil
£333 Return, found 1 day ago
£333
Return
found 1 day ago
Select Copa flight, departing Wed, 13 May from Medellín to Guayaquil, returning Fri, 15 May, priced at £333 found 1 day ago
Copa
Fri, 15 May - Sun, 17 May
MDE
Medellín
GYE
Guayaquil
£334 Return, found 1 day ago
£334
Return
found 1 day ago
Select Copa flight, departing Fri, 15 May from Medellín to Guayaquil, returning Sun, 17 May, priced at £334 found 1 day ago
Copa
Wed, 13 May - Fri, 15 May
MDE
Medellín
GYE
Guayaquil
£339 Return, found 1 day ago
£339
Return
found 1 day ago
Select Copa flight, departing Wed, 13 May from Medellín to Guayaquil, returning Fri, 15 May, priced at £339 found 1 day ago
LATAM Airlines Group
Tue, 5 May - Mon, 25 May
MDE
Medellín
GYE
Guayaquil
£339 Return, found 2 days ago
£339
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 5 May from Medellín to Guayaquil, returning Mon, 25 May, priced at £339 found 2 days ago
Copa
Wed, 13 May - Fri, 15 May
MDE
Medellín
GYE
Guayaquil
£342 Return, found 1 day ago
£342
Return
found 1 day ago
Select Copa flight, departing Wed, 13 May from Medellín to Guayaquil, returning Fri, 15 May, priced at £342 found 1 day ago
avianca
Wed, 13 May - Fri, 15 May
MDE
Medellín
GYE
Guayaquil
£387 Return, found 1 day ago
£387
Return
found 1 day ago
Select avianca flight, departing Wed, 13 May from Medellín to Guayaquil, returning Fri, 15 May, priced at £387 found 1 day ago

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city centre is 9 minutes. Flights from £374
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city centre9 min
Flights from £374

Frequently asked questions

Which airlines fly direct from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
Enter MDE to GYE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
To find a cheap flight from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The best airline to fly with from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) will differ from traveller to traveller. If you like to fly early, AV offers early morning flights. If price is the most important factor, AV typically offers the lowest fares. AV offers the most daily flights from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
There are approximately 43 connecting flights per day from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.). Some common connection points include El Dorado Intl. (BOG), Tocumen Intl. (PTY), and Mariscal Sucre Intl. (UIO).
What is the earliest flight from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The earliest flight from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) typically departs at approximately 12:00 AM local time, operated by Avianca. This is a seasonal service active in May. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
You'll find the most flights from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) on a Thursday, with around 39 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include AV, CM, and LA. Looking at the week, Thursday offers notably more flight options compared to other days, making it a great day to plan your trip.
What are the most popular departure times for flights from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The most popular departure times for flights from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) are in the morning, from 9am to 12pm. About 22% of passengers prefer this time. Many major carriers, including AV and CM, offer flights during this window. This timing works well because it allows for a comfortable morning departure and an afternoon arrival, giving you time to settle in at your destination.
How long does it take to fly from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
A nonstop flight from MDE to GYE typically takes around 2 hours, covering approximately 652 miles. Connecting flights on this route usually add 3 hours to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
Select the "Business class" and "First class" filters when looking for MDE to GYE flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight with Expedia?
It's easy to earn miles on a Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Guayaquil from Jose Maria Cordova Intl. (MDE)?
If you're planning to travel to Guayaquil from Jose Maria Cordova Intl. (MDE), you can fly directly into Jose Joaquin de Olmedo Intl. (GYE) Some flights may connect through major hubs like El Dorado Intl. (BOG) before reaching Guayaquil. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) at the last minute?
Typically, booking a last minute flight from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight and hotel package?
Securing a Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
If you booked your Medellín (MDE-José María Córdova Intl.) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

0
Origin airport
José María Córdova Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Return price
£326
Distance
1042 km

Book with confidence

Compare flights from Medellín to Guayaquil easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Medellín to Guayaquil. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Jose Joaquin de Olmedo Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from José María Córdova Intl. to Jose Joaquin de Olmedo Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from José María Córdova Intl. (MDE) to Jose Joaquin de Olmedo Intl. (GYE)

The easiest way to view the best deals on flights from Medellín to Guayaquil today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from José María Córdova Intl. to Jose Joaquin de Olmedo Intl. start at just £327 and range up to £387.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Medellín and Guayaquil
  • booking your flight during July, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Medellín to Guayaquil flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from José María Córdova Intl. to Jose Joaquin de Olmedo Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Medellín to Guayaquil easily and book with confidence

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