Title: £150 Cheap Flights from Medellín to Guayaquil (MDE to GYE) - Expedia.co.uk ![](https://images.trvl-media.com/place/1414/5a1b814f-6172-4234-8e22-f7c4f67d6424.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1414/5a1b814f-6172-4234-8e22-f7c4f67d6424.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £150 Cheap Flights from Medellín (MDE) to Guayaquil (GYE) [View £150 flight on Fri, 6 Feb 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:MDE,to:GYE,departure:06/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:149.60&airProductToken=AQozCjEIwawBEgQ4Mzk5GOwgIIYmKOq7hAMw4ryEAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5EgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Jose Joaquin de Olmedo Intl. Airport (GYE) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:mde,to:gye,departure:27/10/2025TANYT&leg2=from:gye,to:mde,departure:03/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:mde,to:gye,departure:27/10/2025TANYT&leg2=from:gye,to:mde,departure:03/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.co.uk/Flights-Search?leg1=from:mde,to:gye,departure:27/10/2025TANYT&leg2=from:gye,to:mde,departure:03/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Medellín (MDE) to Guayaquil (GYE) Prices were available within the past 7 days and start at £150 for one-way flights and £260 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Fri, 17 Oct - Mon, 20 Oct MDE Medellin GYE Guayaquil £260 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:17/10/2025TANYT&leg2=from:GYE,to:MDE,departure:20/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:259.10&airProductToken=AQoyCjAIwawBEgMxMzUY7CAghiYog9D6AjDx0PoCOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKMgowCMGsARIDMTM0GIYmIOwgKKzx-gIwkPL6AjhTQABYAWoFQkFTSUNyCFNFT0IwQlI5EgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Wed, 7 Jan - Fri, 9 Jan MDE Medellin GYE Guayaquil £261 Return found 6 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:07/01/2026TANYT&leg2=from:GYE,to:MDE,departure:09/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:260.40&airProductToken=AQozCjEIwawBEgQ4Mzk5GOwgIIYmKJ3rgQMwleyBAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5CjMKMQjBrAESBDgzOTgYhiYg7CAoxf-BAzCzgIIDOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkSCggCEAEYAioCQVYYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Fri, 17 Oct - Mon, 20 Oct MDE Medellin GYE Guayaquil £273 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:17/10/2025TANYT&leg2=from:GYE,to:MDE,departure:20/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:272.40&airProductToken=AQoyCjAIwawBEgMxMzUY7CAghiYog9D6AjDx0PoCOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKZAovCMGsARICOTAYhiYgwTMohe_6AjD37_oCOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKMQjBrAESBDkzMjIYwTMg7CAoxfH6AjCC8voCOFNAAVgBagVCQVNJQ3IIU0VPQjBCUjkSCggCEAEYAioCQVYYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Wed, 7 Jan - Fri, 9 Jan MDE Medellin GYE Guayaquil £273 Return found 6 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:07/01/2026TANYT&leg2=from:GYE,to:MDE,departure:09/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:272.60&airProductToken=AQozCjEIwawBEgQ4Mzk5GOwgIIYmKJ3rgQMwleyBAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5CmYKMQjBrAESBDgzOTQYhiYgwTMo-4GCAzDpgoIDOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKMQjBrAESBDkzNDIYwTMg7CAo3IOCAzCYhIIDOFNAAVgBagVCQVNJQ3IIU0VPQjBCUjkSCggCEAEYAioCQVYYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Fri, 17 Oct - Mon, 20 Oct MDE Medellin GYE Guayaquil £285 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:17/10/2025TANYT&leg2=from:GYE,to:MDE,departure:20/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:284.60&airProductToken=AQpkCjEIwawBEgQ5MjQ1GOwgIMEzKNPK-gIwkcv6AjhTQABYAWoFQkFTSUNyCFNFT0IwQlI5Ci8IwawBEgI3NxjBMyCGJijSzfoCMMDO-gI4U0ABWAFqBUJBU0lDcghTRU9CMEJSOQpkCi8IwawBEgI5MBiGJiDBMyiF7_oCMPfv-gI4U0AAWAFqBUJBU0lDcghTRU9CMEJSOQoxCMGsARIEOTMxMBjBMyDsICjn8PoCMKDx-gI4U0ABWAFqBUJBU0lDcghTRU9CMEJSORIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Wed, 7 Jan - Fri, 9 Jan MDE Medellin GYE Guayaquil £286 Return found 6 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:07/01/2026TANYT&leg2=from:GYE,to:MDE,departure:09/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:285.90&airProductToken=AQpmCjEIwawBEgQ5Mzc1GOwgIMEzKKfrgQMw3uuBAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5CjEIwawBEgQ4MzkxGMEzIIYmKODsgQMw0-2BAzhTQAFYAWoFQkFTSUNyCFNFT0IwQlI5CmQKLwjBrAESAjc2GIYmIMEzKLOAggMwoYGCAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5CjEIwawBEgQ5MzQyGMEzIOwgKNyDggMwmISCAzhTQAFYAWoFQkFTSUNyCFNFT0IwQlI5EgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Mon, 12 Jan - Mon, 19 Jan MDE Medellin GYE Guayaquil £288 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:12/01/2026TANYT&leg2=from:GYE,to:MDE,departure:19/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:287.30&airProductToken=AQozCjEIwawBEgQ4Mzk5GOwgIIYmKLaiggMwrqOCAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5EgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sun, 11 Jan - Sun, 18 Jan MDE Medellin GYE Guayaquil £290 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:11/01/2026TANYT&leg2=from:GYE,to:MDE,departure:18/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:289.20&airProductToken=AQpmCjEIwawBEgQ5MzU3GOwgIMEzKPiRggMwuZKCAzhTQABYAWoFQkFTSUNyCFNFT0IwQlI5CjEIwawBEgQ4Mzg1GMEzIIYmKISTggMw95OCAzhTQAFYAWoFQkFTSUNyCFNFT0IwQlI5EgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Fri, 17 Oct - Mon, 20 Oct MDE Medellin GYE Guayaquil £290 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:17/10/2025TANYT&leg2=from:GYE,to:MDE,departure:20/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:289.60&airProductToken=AQqQAQouCMyCARIENDAxMRjsICDBMyjAy_oCMPrL-gI4UUAAWAFqAlFQcghRTEVRUFowSwouCMyCARIEMTQ0MRjBMyCUcijkzPoCMMjN-gI4UUABWAFqAlFQcghRTEVRUFowSwouCMyCARIEMTM2MRiUciCGJiiGzvoCMLvO-gI4UUABWAFqAlFQcghRTEVRUFowSxIKCAEQARgBKgJMQRgBIgQIARABKAIoBCgGMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Wed, 14 Jan - Wed, 21 Jan MDE Medellin GYE Guayaquil £301 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:14/01/2026TANYT&leg2=from:GYE,to:MDE,departure:21/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:300.40&airProductToken=AQpmCjEIw5oBEgM3NjYY7CAg78QBKIq5ggMw4bmCAzhFQABYAWoFQkFTSUNyCEVMQUFPWjJTCjEIw5oBEgMyMTMY78QBIIYmKP-5ggMwiruCAzhFQAFYAWoFQkFTSUNyCEVMQUFPWjJTEgoIARABGAEqAkNNGAEiBAgBEAEoAigDKAQwAQ) ## Find the cheapest month to fly from Medellín (MDE) to Guayaquil (GYE) ### February is typically the cheapest month to fly From £175 - £353 per traveller. Flight from Medellín to Guayaquil route information | Origin airport | José María Córdova Intl. | | --- | --- | | Destination airport | Jose Joaquin de Olmedo Intl. | | Airlines serving | Copa, LATAM Airlines Group, avianca | | Return price | £259 | | Distance | 1042 km | | Average flight time | 1 hour 50 mins | ## Compare flights from Medellín to Guayaquil easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Medellín to Guayaquil. Operating between them 1 flights per day, 20 airlines cover the route. And Avianca fly direct, getting you to Jose Joaquin de Olmedo Intl. in just 1hours. If you have a preferred carrier, use our advanced search tool to find the right flight from José María Córdova Intl. to Jose Joaquin de Olmedo Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from José María Córdova Intl. (MDE) to Jose Joaquin de Olmedo Intl. (GYE) The easiest way to view the best deals on flights from Medellín to Guayaquil today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from José María Córdova Intl. to Jose Joaquin de Olmedo Intl. start at just £260 and range up to £301.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Medellín and Guayaquil - booking your flight during October, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Medellín to Guayaquil flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from José María Córdova Intl. to Jose Joaquin de Olmedo Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Frequently asked questions ### How much is a flight from MDE to GYE? > Round-trip journeys from Medellin Airport to GYE start from £260. This price is based on fares available within the last 7 days on Expedia for flights departing within the next year — book ASAP so you don't miss out. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Medellin Airport to GYE? > We understand that your situation can change unexpectedly, so we've made it as easy as possible for you to cancel your trip online. Just visit the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033) and follow the instructions. ### How do I find cheap flights from MDE to Jose Joaquin de Olmedo Intl. Airport (GYE) that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Medellin Airport to Jose Joaquin de Olmedo Intl. Airport (GYE) flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from Medellin Airport to GYE? > You won't have time for a movie marathon on this flight — it's just 1,050 kilometres from Rionegro to Guayas. Find your way to your seat, buckle up and you'll be touching down before you know it. ### Which airlines fly direct from MDE to GYE? > Currently, no airlines offer flights directly from Jose Maria Cordova Intl. Airport (MDE) to Airport of Guayaquil. You'll have to book a flight with one or more stops. To get the best connections and price, lock in your airfare well in advance. ### Are Jose Maria Cordova Intl. Airport (MDE) to GYE flight tickets cheaper when they're purchased at the last minute? > Flight prices are always on the move, so not always. While last-minute flight deals between Medellin Airport and Airport of Guayaquil are of course possible, it also makes sense to keep a close eye on prices well before you fly. In fact, some air carriers release their prices up to a year prior to the departure date. 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[Urdesa Hotels](https://www.expedia.co.uk/Urdesa-Guayaquil-Hotels.0-n553248633981744847-0.Travel-Guide-Filter-Hotels) ### Flights - [Flights to Duran](https://www.expedia.co.uk/Cheap-Flights-To-Duran.d6325948.Travel-Guide-Flights) - [Flights to Guayaquil](https://www.expedia.co.uk/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights) - [Flights to Guayaquil](https://www.expedia.co.uk/Cheap-Flights-To-Guayaquil.d6337570.Travel-Guide-Flights) - [Flights to Morro](https://www.expedia.co.uk/Cheap-Flights-To-Morro.d3000399325.Travel-Guide-Flights) - [Flights to Playas](https://www.expedia.co.uk/Cheap-Flights-To-Playas.d6157902.Travel-Guide-Flights) - [Flights to Guayas](https://www.expedia.co.uk/Destinations-In-Guayas.d6239779.Flight-Destinations) - [Flights from Victoria](https://www.expedia.co.uk/lp/flights/553248635975860786/flights-from-victoria) - [Flights from Hacienda San Juan](https://www.expedia.co.uk/lp/flights/553248635975870510/flights-from-hacienda-san-juan) ### Packages - [Dr. Teodoro Maldonado Carbo Hospital](https://www.expedia.co.uk/Dr-Teodoro-Maldonado-Carbo-Hospital-Guayaquil.d6331051.Attraction) - 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