Title: £603 Cheap Flights from Manchester to Des Moines (MAN to DSM) - Expedia.co.uk ![Iowa State Capitol](https://images.trvl-media.com/place/601690/d6e0e2f2-7876-4d18-865a-ae2f68f4627c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/601690/d6e0e2f2-7876-4d18-865a-ae2f68f4627c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £603 Cheap Flights from Manchester (MAN) to Des Moines (DSM) [View £603 flight on Mon, 24 Nov 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:MAN,to:DSM,departure:24/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:602.91&airProductToken=AQqZAQoyCMGCARIENjYxOBiMaCDriQEo9vT9AjDB9f0COE9AAFgBagVCQVNJQ3IIT0xYNUM1QjQKMAjBggESAjg3GOuJASCuHCiT9_0CMKX7_QI4QkABWAFqBUJBU0lDcghPTFg1QzVCNAoxCMGCARIENjI5MhiuHCDDZCiC_P0CMN38_QI4QkABWAFqBUJBU0lDcghPTFg1QzVCNBIKCAIQARgCKgJBQRgBIgQIARABKAIoAygEMAs) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Manchester Airport (MAN) to Des Moines International Airport (DSM) - ![Aer Lingus](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_EI.svg) Aer Lingus [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"EI"}}]) - ![Virgin Atlantic](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_VS.svg) Virgin Atlantic [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"VS"}}]) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![Lufthansa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}]) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:man,to:dsm,departure:29/09/2025TANYT&leg2=from:dsm,to:man,departure:06/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Manchester (MAN) to Des Moines (DSM) Prices were available within the past 7 days and start at £603 for one-way flights and £617 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif) Fri, 1 May - Thu, 7 May MAN Manchester DSM Des Moines £617 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:01/05/2026TANYT&leg2=from:DSM,to:MAN,departure:07/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:616.37&airProductToken=AQqdAQoyCNOWARIDNTQyGIxoIOI7KKLriwMwkOyLAzhMQABYAWoIU1RBTkRBUkRyB0xMRVU2RVMKMgjTlgESAzkyORjiOyDgXCi384sDMIX4iwM4TEABWAFqCFNUQU5EQVJEcgdMTEVVNkVTCjMI05YBEgQzMjMwGOBcIMNkKOb5iwMw7PqLAzhMQAFYAWoIU1RBTkRBUkRyB0xMRVU2RVMKnQEKMwjTlgESBDMyMzEYw2Qg4Fwoo6-MAzCosIwDOExAAFgBaghTVEFOREFSRHIHTExFVTZFUwoyCNOWARIDOTMwGOBcIOI7KJ2xjAMwr7WMAzhMQAFYAWoIU1RBTkRBUkRyB0xMRVU2RVMKMgjTlgESAzUzORjiOyCMaCjDv4wDMLvAjAM4TEABWAFqCFNUQU5EQVJEcgdMTEVVNkVTEgoIARABGAEqAlNLGAEiBAgBEAEoAigDKAQwAQ) ![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif) Wed, 19 Nov - Mon, 1 Dec MAN Manchester DSM Des Moines £626 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:19/11/2025TANYT&leg2=from:DSM,to:MAN,departure:01/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:625.52&airProductToken=AQqdAQoyCNOWARIDNTQyGIxoIOI7KIPC_QIw8cL9AjhMQABYAWoIU1RBTkRBUkRyB0xMRVU2RVMKMgjTlgESAzkyORjiOyDgXCj_yf0CMOHO_QI4TEABWAFqCFNUQU5EQVJEcgdMTEVVNkVTCjMI05YBEgQzMjMwGOBcIMNkKMzQ_QIw0dH9AjhMQAFYAWoIU1RBTkRBUkRyB0xMRVU2RVMKnQEKMwjTlgESBDMyMzEYw2Qg4Fwowcn-AjC8yv4COExAAFgBaghTVEFOREFSRHIHTExFVTZFUwoyCNOWARIDOTMwGOBcIOI7KNzL_gIw5M_-AjhMQAFYAWoIU1RBTkRBUkRyB0xMRVU2RVMKMgjTlgESAzU0MRjiOyCMaCiD0_4CMPvT_gI4TEABWAFqCFNUQU5EQVJEcgdMTEVVNkVTEgoIARABGAEqAlNLGAEiBAgBEAEoAigDKAQwAQ) ![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif) Tue, 23 Sept - Mon, 20 Oct MAN Manchester DSM Des Moines £648 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:23/09/2025TANYT&leg2=from:DSM,to:MAN,departure:20/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:647.46&airProductToken=AQqaAQoxCNOWARIDNTQyGIxoIOI7KKLA-AIwkMH4AjhOQABYAWoHR09TTUFSVHIHTkxFVTZFUwoxCNOWARIDOTI5GOI7IOBcKK3I-AIwgM34AjhOQAFYAWoHR09TTUFSVHIHTkxFVTZFUwoyCNOWARIEMzIzMBjgXCDDZCj6zvgCMPnP-AI4TkABWAFqB0dPU01BUlRyB05MRVU2RVMKmgEKMgjTlgESBDMyMzEYw2Qg4FwowfD6AjC-8foCOExAAFgBagdHT1NNQVJUcgdMTEVVNkVTCjEI05YBEgM5MzAY4Fwg4jso2_L6AjDy9voCOExAAVgBagdHT1NNQVJUcgdMTEVVNkVTCjEI05YBEgM1NDEY4jsgjGgoh_r6AjD6-voCOExAAVgBagdHT1NNQVJUcgdMTEVVNkVTEgoIARABGAEqAlNLGAEiBAgBEAEoAigDKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, 24 Nov - Mon, 1 Dec MAN Manchester DSM Des Moines £738 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:24/11/2025TANYT&leg2=from:DSM,to:MAN,departure:01/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:737.88&airProductToken=AQqZAQoyCMGCARIENjYxOBiMaCDriQEo9vT9AjDB9f0COE9AAFgBagVCQVNJQ3IIT0xYN0cxQjQKMAjBggESAjg3GOuJASCuHCiT9_0CMKX7_QI4QkABWAFqBUJBU0lDcghPTFg3RzFCNAoxCMGCARIENjI5MhiuHCDDZCiC_P0CMN38_QI4QkABWAFqBUJBU0lDcghPTFg3RzFCNAqbAQoxCMGCARIENDcxMRjDZCCuHCipyf4CMITK_gI4QkAAWAFqBUJBU0lDcghPTFg3RzFCNAoyCMGCARIENzAwMxiuHCDriQEo7sr-AjC_zv4COE9AAVgBagVCQVNJQ3IIT0xYN0cxQjQKMgjBggESBDcxNzgY64kBIIxoKKjP_gIw6c_-AjhPQAFYAWoFQkFTSUNyCE9MWDdHMUI0EgoIAhABGAIqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, 24 Nov - Mon, 1 Dec MAN Manchester DSM Des Moines £739 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:24/11/2025TANYT&leg2=from:DSM,to:MAN,departure:01/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:738.88&airProductToken=AQqcAQoyCMGCARIENzE2MRiMaCDriQEo5vb9AjCx9_0COE9AAFgBagVCQVNJQ3IIT0xYN0cxQjQKMgjBggESAzczNRjriQEg4poBKJX4_QIwu_z9AjhCQAFYAWoFQkFTSUNyCE9MWDdHMUI0CjIIwYIBEgQ1NDM4GOKaASDDZCjj_f0CMIr__QI4QkABWAFqBUJBU0lDcghPTFg3RzFCNAqaAQoxCMKCARIENDM2MBjDZCCuHCipyf4CMITK_gI4T0AAWAFqBU5PQkFHcghPTFg3RzFCNAoxCMKCARIDMjk0GK4cIOuJASjuyv4CML_O_gI4T0ABWAFqBU5PQkFHcghPTFg3RzFCNAoyCMKCARIEMTM2NhjriQEgjGgooND-AjDh0P4COE9AAVgBagVOT0JBR3IIT0xYN0cxQjQSCggCEAEYAioCQUEYASIECAEQASgCKAMoBDAB) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Tue, 11 Nov - Tue, 18 Nov MAN Manchester DSM Des Moines £740 Return just found [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:11/11/2025TANYT&leg2=from:DSM,to:MAN,departure:18/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:739.88&airProductToken=AQqeAQozCMKCARIEMTM1ORiMaCDriQEol-P8AjDi4_wCOE9AAFgBagVOT0JBR3IJT0xYN0cxQjRQCjMIwoIBEgQxNTQ2GOuJASCuHCjS5fwCMOTp_AI4T0ABWAFqBU5PQkFHcglPTFg3RzFCNFAKMgjCggESBDUxODUYrhwgw2Qovuv8AjCY7PwCOE9AAVgBagVOT0JBR3IJT0xYN0cxQjRQCp0BCjIIwoIBEgQ0MzU4GMNkIK4cKKi5_QIwmLr9AjhPQABYAWoFTk9CQUdyCU9MWDdHMUI0UAoyCMKCARIDMjk2GK4cIOuJASjhuv0CMLe-_QI4T0ABWAFqBU5PQkFHcglPTFg3RzFCNFAKMwjCggESBDEzNjgY64kBIIxoKIe__QIwyL_9AjhPQAFYAWoFTk9CQUdyCU9MWDdHMUI0UBIKCAEQARgBKgJCQRgBIgQIARABKAIoAzAN) ![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif) Tue, 21 Oct - Sun, 26 Oct MAN Manchester DSM Des Moines £745 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:21/10/2025TANYT&leg2=from:DSM,to:MAN,departure:26/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:744.85&airProductToken=AQqdAQoyCNOWARIDNTQyGIxoIOI7KKL7-gIwkPz6AjhMQABYAWoIU1RBTkRBUkRyB0xMRVU2RVMKMgjTlgESAzkyORjiOyDgXCitg_sCMICI-wI4TEABWAFqCFNUQU5EQVJEcgdMTEVVNkVTCjMI05YBEgQzMjMwGOBcIMNkKPCJ-wIw8or7AjhMQAFYAWoIU1RBTkRBUkRyB0xMRVU2RVMKnQEKMwjTlgESBDMyMzEYw2Qg4FwogbT7AjD-tPsCOEtAAFgBaghTVEFOREFSRHIHS0xFVTZFUwoyCNOWARIDOTMwGOBcIOI7KNy2-wIw5Lr7AjhLQAFYAWoIU1RBTkRBUkRyB0tMRVU2RVMKMgjTlgESAzU0MRjiOyCMaCiDvvsCMPu--wI4S0ABWAFqCFNUQU5EQVJEcgdLTEVVNkVTEgoIARABGAEqAlNLGAEiBAgBEAEoAigDKAQwAQ) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Mon, 24 Nov - Mon, 1 Dec MAN Manchester DSM Des Moines £748 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:24/11/2025TANYT&leg2=from:DSM,to:MAN,departure:01/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:747.88&airProductToken=AQqYAQoxCMKCARIEMTM1ORiMaCDriQEot_X9AjCC9v0COE9AAFgBagRFQ01QcghPTFg3RzFCNAoxCMGyARIEMzg4NhjriQEgrhwok_f9AjCl-_0COE9AAVgBagRFQ01QcghPTFg3RzFCNAowCMGCARIENjI5MhiuHCDDZCiC_P0CMN38_QI4QkABWAFqBEVDTVByCE9MWDdHMUI0CpsBCjIIwYIBEgQzMTkxGMNkIKOxASj-yv4CMP7L_gI4QkAAWAFqBUJBU0lDcghPTFg3RzFCNAoxCMGCARICNzgYo7EBIOuJASjAzP4CMNzQ_gI4QkABWAFqBUJBU0lDcghPTFg3RzFCNAoyCMGCARIENzEyOBjriQEgjGgo7dH-AjCu0v4COE9AAVgBagVCQVNJQ3IIT0xYN0cxQjQSCggCEAEYAioCQVkYASIECAEQASgCKAMoBDAB) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Tue, 25 Nov - Tue, 9 Dec MAN Manchester DSM Des Moines £755 Return found 20 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:25/11/2025TANYT&leg2=from:DSM,to:MAN,departure:09/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:754.37&airProductToken=AQqiAQo0CMyQARIENDEyNxiMaCCMFSjB__0CMLmA_gI4S0AAWAFqCEVDT0xJR0hUcghLTDVNUERCUQo0CMyQARIEOTI2OBiMFSCuHCixgf4CMPqF_gI4S0ABWAFqCEVDT0xJR0hUcghLTDVNUERCUQo0CMyQARIEODc4MhiuHCDDZCjthv4CML2H_gI4S0ABWAFqCEVDT0xJR0hUcghLTDVNUERCUQqhAQo0CMyQARIENzYzNRjDZCCuHCjSpf8CMLGm_wI4S0AAWAFqCEVDT0xJR0hUcghLTDVNUERCUQozCMyQARIDNDM1GK4cIIwVKIan_wIw-qr_AjhLQAFYAWoIRUNPTElHSFRyCEtMNU1QREJRCjQIzJABEgQ0MTI2GIwVIIxoKJGv_wIwmLD_AjhLQAFYAWoIRUNPTElHSFRyCEtMNU1QREJREgoIAhABGAIqAkxIGAEiBAgBEAEoAigDKAQwCw) ![Finnair](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AY.gif) Tue, 11 Nov - Tue, 18 Nov MAN Manchester DSM Des Moines £756 Return just found [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MAN,to:DSM,departure:11/11/2025TANYT&leg2=from:DSM,to:MAN,departure:18/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:755.88&airProductToken=AQqaAQoxCMGyARIENjU3NBiMaCDriQEo9eX8AjC75vwCOE9AAFgBagRFQ01QcghPTFg3RzFCNAoyCMGyARIEMzc0MRjriQEgo7EBKP3u_AIw6fP8AjhPQAFYAWoERUNNUHIIT0xYN0cxQjQKMQjBsgESBDQyNTUYo7EBIMNkKOv0_AIw2PX8AjhPQAFYAWoERUNNUHIIT0xYN0cxQjQKmwEKMQjJhAESBDQ4MzYYw2Qgrhwoo7f9AjCKuP0COE9AAFgBagVCQVNJQ3IIT0xYN0cxQjQKMgjJhAESBDQyMDgYrhwg64kBKJ65_QIw77z9AjhPQAFYAWoFQkFTSUNyCE9MWDdHMUI0CjIIwoIBEgQxMzY0GOuJASCMaCjTvf0CMJS-_QI4U0ABWAFqBUJBU0lDcghPTFg3RzFCNBIKCAIQARgCKgJBWRgBIgQIARABKAIoAygEMAE) Flight from Manchester to Des Moines route information | Origin airport | Manchester | | --- | --- | | Destination airport | Des Moines Intl. | | Airlines serving | Aer Lingus, Air France, British Airways, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, Virgin Atlantic | | Return price | £616 | | Distance | 6475 km | ## Compare flights from Manchester to Des Moines easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Manchester to Des Moines. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Des Moines Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Manchester to Des Moines Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Manchester (MAN) to Des Moines Intl. (DSM) The easiest way to view the best deals on flights from Manchester to Des Moines today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Manchester to Des Moines Intl. start at just £617 and range up to £756.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Manchester and Des Moines - booking your flight during May, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Manchester to Des Moines flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Manchester to Des Moines Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Trending Routes - Top Flights Destinations - Related Airlines - Nearby Airports - Cheap Flights from Other Airports - Expedia's Latest Trends ### Top Routes to Des Moines - [Bristol to Des Moines (BRS - DSM)](https://expedia.co.uk/lp/flights/brs/dsm/bristol-to-des-moines) - [Durham to Des Moines (MME - DSM)](https://expedia.co.uk/lp/flights/mme/dsm/durham-to-des-moines) - [Portland to Des Moines (PDX - DSM)](https://expedia.co.uk/lp/flights/pdx/dsm/portland-to-des-moines) - [Leeds to Des Moines (LBA - DSM)](https://expedia.co.uk/lp/flights/lba/dsm/leeds-to-des-moines) - [Edinburgh to Des Moines (EDI - DSM)](https://expedia.co.uk/lp/flights/edi/dsm/edinburgh-to-des-moines) - [Dublin to Des Moines (DUB - DSM)](https://expedia.co.uk/lp/flights/dub/dsm/dublin-to-des-moines) - [Newcastle to Des Moines (NCL - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)