£151 Cheap Flights from Key West (EYW) to San Francisco (SFO)

View £151 flight on Sat, 14 Feb 2026Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to San Francisco International Airport (SFO)

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Cheap Flights from Key West (EYW) to San Francisco (SFO)

Prices were available within the past 7 days and start at £151 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Find the cheapest month to fly from Key West (EYW) to San Francisco (SFO)

October is typically the cheapest month to fly

From £170 - £533 per traveller.

Graph displaying average flight prices per month

Flight from Key West to San Francisco route information
Origin airport
Key West Intl.
Destination airport
San Francisco Intl.
Distance
4071 km

Compare flights from Key West to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Key West to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Key West Intl. to San Francisco Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Key West Intl. (EYW) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Key West to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Key West Intl. to San Francisco Intl. start at just and range up to .  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Key West and San Francisco
  • booking your flight during , the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Key West to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Key West Intl. to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Frequently asked questions

How much is a flight from EYW to San Francisco Intl. Airport (SFO)?
Round-trip flights between Key West Intl. Airport (EYW) and SFO start from . This figure is based on fares offered within the last 7 days on Expedia for flights departing within the next year — book ASAP to avoid missing out. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Key West Intl. Airport (EYW) to SFO?
This can vary between airlines, as each has its own terms and conditions. Visit the Customer Service Portal, where there are instructions on how to cancel your flight online.
How do I find cheap flights from Key West Intl. Airport (EYW) to San Francisco Intl. Airport (SFO) that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Key West Intl. Airport to SFO flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Key West Intl. Airport (EYW) to San Francisco Airport?
With a flight distance of 4,100 kilometres from EYW to SFO, this is a long-haul flight. Be sure to drink plenty of water and get up to stretch your legs from time to time.
Which airlines fly direct from Key West Intl. Airport (EYW) to SFO?
Unfortunately, there are no airlines that fly direct between Key West Intl. Airport (EYW) and SFO. You'll need to book a flight with one or more stops.
Are EYW to San Francisco Intl. Airport (SFO) flight tickets cheaper when they're purchased at the last minute?
Flight prices always go up and down, so not always. While last-minute deals between Key West Intl. Airport and San Francisco Intl. Airport (SFO) are of course possible, it also makes sense to monitor prices well before you fly. In fact, some airlines release their prices up to 12 months prior to the departure date. Expedia is continuously updating the biggest bargains around, so check back often and be ready to pounce when the price is low.

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