Title: £428 Cheap Flights from Key West to San Francisco (EYW to SFO) - Expedia.co.uk ![Sunset view of the Golden Gate Bridge and fog from Battery Spencer, Golden Gate National Recreation Area, in San Francisco, California.](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £428 Cheap Flights from Key West (EYW) to San Francisco (SFO) [View £428 flight on Sat, 22 Nov 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:EYW,to:SFO,departure:22/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:427.70&airProductToken=AQpgCi8IwmwSBDIwNjQYhLYBIMGTASiO4_0CMOHk_QI4VkAAWAFqAkFOcghWSTBBVUVZNQotCMJsEgM3MzMYwZMBILJxKN_m_QIw9un9AjhTQAFYAWoCQU5yCFNJMkFCRVk1EgoIARABGAEqAkI2GAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Key West Intl. Airport (EYW) to San Francisco International Airport (SFO) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:eyw,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:eyw,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:eyw,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:eyw,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:eyw,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:eyw,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Key West (EYW) to San Francisco (SFO) Prices were available within the past 7 days and start at £428 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ## Find the cheapest month to fly from Key West (EYW) to San Francisco (SFO) ### October is typically the cheapest month to fly From £175 - £526 per traveller. Flight from Key West to San Francisco route information | Origin airport | Key West Intl. | | --- | --- | | Destination airport | San Francisco Intl. | | Distance | 4071 km | ## Frequently asked questions ### How much is a flight from EYW to San Francisco Intl. Airport (SFO)? > Round-trip flights between Key West Intl. Airport (EYW) and SFO start from . This figure is based on fares offered within the last 7 days on Expedia for flights departing within the next year — book ASAP to avoid missing out. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Key West Intl. Airport (EYW) to SFO? > This can vary between airlines, as each has its own terms and conditions. Visit the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033), where there are instructions on how to cancel your flight online. ### How do I find cheap flights from Key West Intl. Airport (EYW) to San Francisco Intl. Airport (SFO) that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Key West Intl. Airport to SFO flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from Key West Intl. Airport (EYW) to San Francisco Airport? > With a flight distance of 4,100 kilometres from EYW to SFO, this is a long-haul flight. Be sure to drink plenty of water and get up to stretch your legs from time to time. ### Which airlines fly direct from Key West Intl. Airport (EYW) to SFO? > Unfortunately, there are no airlines that fly direct between Key West Intl. Airport (EYW) and SFO. You'll need to book a flight with one or more stops. ### Are EYW to San Francisco Intl. Airport (SFO) flight tickets cheaper when they're purchased at the last minute? > Flight prices always go up and down, so not always. While last-minute deals between Key West Intl. Airport and San Francisco Intl. Airport (SFO) are of course possible, it also makes sense to monitor prices well before you fly. In fact, some airlines release their prices up to 12 months prior to the departure date. 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