Title: Cheap Flights from Des Moines to San Francisco (DSM to SFO) - Expedia.co.uk ![Sunset view of the Golden Gate Bridge and fog from Battery Spencer, Golden Gate National Recreation Area, in San Francisco, California.](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Des Moines (DSM) to San Francisco (SFO) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Des Moines International Airport (DSM) to San Francisco International Airport (SFO) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:dsm,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:dsm,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:dsm,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:dsm,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:dsm,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:sfo,departure:01/10/2025TANYT&leg2=from:sfo,to:dsm,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Des Moines (DSM) to San Francisco (SFO) Prices were available within the past 7 days and start at for one-way flights and £518 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Thu, 30 Oct - Thu, 6 Nov DSM Des Moines SFO San Francisco £518 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:DSM,to:SFO,departure:30/10/2025TANYT&leg2=from:SFO,to:DSM,departure:06/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:517.10&airProductToken=AQpiCi8IwaYBEgQ0NTI2GMNkIO-5ASiQ4fsCMMvi-wI4R0AAWAFqAlBNcghRV0FJWk5NMwovCMGmARIEMjAwORjvuQEgsnEol-T7AjCZ5fsCOFFAAVgBagJQTXIIUVdBSVpOTTMKWwoqCMGmARIBOBiycSBDKImv_AIwwrH8AjhWQABYAWoCUE1yCFY3QUlaTk4xCi0IwaYBEgQ0MDMzGEMgw2Qou7L8AjDys_wCOE5AAVgBagJQTXIIVjdBSVpOTjESCggBEAEYASoCQVMYASIECAEQASgCKAMoBDAB) ## Find the cheapest month to fly from Des Moines (DSM) to San Francisco (SFO) ### October is typically the cheapest month to fly From £102 - £331 per traveller. Flight from Des Moines to San Francisco route information | Origin airport | Des Moines Intl. | | --- | --- | | Destination airport | San Francisco Intl. | | Return price | £517 | | Distance | 2474 km | | Average flight time | 13 hours 5 mins | ## Compare flights from Des Moines to San Francisco easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Des Moines to San Francisco. Operating between them flights per day, 1 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Des Moines Intl. to San Francisco Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Des Moines Intl. (DSM) to San Francisco Intl. (SFO) The easiest way to view the best deals on flights from Des Moines to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Des Moines Intl. to San Francisco Intl. start at just £518 and range up to £518.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Des Moines and San Francisco - booking your flight during October, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Des Moines to San Francisco flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Des Moines Intl. to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Frequently asked questions ### How much is a flight from DSM to San Francisco Intl. Airport (SFO)? > Start packing your suitcase, because round-trip flights between DSM and SFO start from £518. That's based on airfares available within the last 7 days on Expedia for flights departing within the next year. Prices can increase quickly, so book now to get the best deal. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport (DSM) to San Francisco Intl. Airport (SFO)? > Most flights can be cancelled online, but each airline has its own set of terms and conditions. If you do need to cancel your flight, visit our [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033) and follow the instructions. ### How do I find cheap flights from Des Moines Intl. Airport (DSM) to San Francisco Airport that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Des Moines Intl. Airport to San Francisco Intl. Airport (SFO) flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from DSM to San Francisco Intl. Airport (SFO)? > It's around 2,500 kilometres between Des Moines and San Francisco, so you'll be flying for a while. Keep yourself entertained by packing things like playing cards (if you're travelling with friends) or a good old-fashioned book. ### Which airlines fly direct from Des Moines Intl. Airport (DSM) to San Francisco Intl. Airport (SFO)? > Currently, no airlines offer direct flights from DSM to San Francisco Airport. You'll have to book a flight with one or more stops. To score the best connections and price, lock in your airfare ahead of time. ### Are DSM to San Francisco Intl. Airport (SFO) flight tickets cheaper when they're purchased at the last minute? > It is possible to get amazing last-minute deals from DSM to SFO, but there's no guarantee. As many airlines advertise prices up to 12 months in advance, it's worthwhile keeping an eye on fares early and being ready to book when you spot a bargain. 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