Title: Cheap Flights from Des Moines to San Diego (DSM to SAN) - Expedia.co.uk ![](https://images.trvl-media.com/place/3073/476a7863-1b66-47b5-9758-1dc7b3787493.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3073/476a7863-1b66-47b5-9758-1dc7b3787493.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Des Moines (DSM) to San Diego (SAN) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Des Moines International Airport (DSM) to San Diego Intl. Airport (SAN) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:san,departure:30/09/2025TANYT&leg2=from:san,to:dsm,departure:07/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:san,departure:30/09/2025TANYT&leg2=from:san,to:dsm,departure:07/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:san,departure:30/09/2025TANYT&leg2=from:san,to:dsm,departure:07/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:san,departure:30/09/2025TANYT&leg2=from:san,to:dsm,departure:07/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:san,departure:30/09/2025TANYT&leg2=from:san,to:dsm,departure:07/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dsm,to:san,departure:30/09/2025TANYT&leg2=from:san,to:dsm,departure:07/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 25% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Des Moines (DSM) to San Diego (SAN) Prices were available within the past 7 days and start at for one-way flights and £375 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Fri, 9 Jan - Tue, 13 Jan DSM Des Moines SAN San Diego £375 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:DSM,to:SAN,departure:09/01/2026TANYT&leg2=from:SAN,to:DSM,departure:13/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:374.70&airProductToken=AQqRAQovCMGmARIENjYzOBjDZCCjsQEogICCAzCDgYIDOE5AAFgBagJQTXIITldBSVpOTTMKLgjBpgESAzMxNxijsQEgkgEo9oGCAzCGhIIDOE5AAVgBagJQTXIITldBSVpOTTMKLgjBpgESBDEzNjkYkgEgkmgou4SCAzDnhYIDOE5AAVgBagJQTXIITldBSVpOTTMKYAouCMGmARIEMTQ5NRiSaCCuHCilq4IDMI-tggM4UUAAWAFqAlBNcghRV0FaS05NMwouCMGmARIENDU2OBiuHCDDZCjCrYIDMJauggM4R0ABWAFqAlBNcghRV0FaS05NMxIKCAEQARgBKgJBUxgBIgQIARABKAIoAygEMAE) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Fri, 9 Jan - Tue, 13 Jan DSM Des Moines SAN San Diego £419 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:DSM,to:SAN,departure:09/01/2026TANYT&leg2=from:SAN,to:DSM,departure:13/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:418.80&airProductToken=AQqQAQovCMGmARIENDEzMxjDZCCjsQEo9fuBAzCI_YEDOFNAAFgBagJQTXIIU1VBSVpOTTEKLgjBpgESAzU0MxijsQEgkgEooP6BAzCwgIIDOFNAAVgBagJQTXIIU1VBSVpOTTEKLQjBpgESAzY5NxiSASCSaCj7gYIDMKeDggM4U0ABWAFqAlBNcghTVUFJWk5NMQpgCi4IwaYBEgQxNDk1GJJoIK4cKKWrggMwj62CAzhRQABYAWoCUE1yCFFXQVpLTk0zCi4IwaYBEgQ0NTY4GK4cIMNkKMKtggMwlq6CAzhHQAFYAWoCUE1yCFFXQVpLTk0zEgoIARABGAEqAkFTGAEiBAgBEAEoAigDKAQwAQ) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Fri, 9 Jan - Tue, 13 Jan DSM Des Moines SAN San Diego £439 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:DSM,to:SAN,departure:09/01/2026TANYT&leg2=from:SAN,to:DSM,departure:13/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:438.70&airProductToken=AQpiCi8IwaYBEgQ0MTM1GMNkIO-5ASjHgIIDMIqCggM4R0AAWAFqAlBNcghRVUFJWk5OMQovCMGmARIEMzA2ORjvuQEgkmgouIOCAzCChIIDOFFAAVgBagJQTXIIUVVBSVpOTjEKYAouCMGmARIEMTQ5NRiSaCCuHCilq4IDMI-tggM4UUAAWAFqAlBNcghRV0FaS05NMwouCMGmARIENDU2OBiuHCDDZCjCrYIDMJauggM4R0ABWAFqAlBNcghRV0FaS05NMxIKCAEQARgBKgJBUxgBIgQIARABKAIoAygEMAE) ## Find the cheapest month to fly from Des Moines (DSM) to San Diego (SAN) ### November is typically the cheapest month to fly From £102 - £408 per traveller. ## Frequently asked questions ### How much is a flight from DSM to SAN? > Within the past 7 days on Expedia, for flights departing within the next year, the lowest price listed for a round-trip journey between Des Moines Intl. Airport (DSM) and San Diego Intl. Airport (SAN) was £375. Fares this cheap don't last long, so make sure you book yours ASAP. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport to San Diego Airport? > This can vary from airline to airline, as each one has its own set of terms and conditions. Visit the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033), where you'll find simple instructions on how to cancel online. ### How do I find cheap flights from Des Moines Intl. Airport to San Diego Intl. Airport (SAN) that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN) flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from DSM to San Diego Airport? > You'll be cruising at altitude for a while, as the flight distance from Des Moines to San Diego is 2,300 kilometres. Put together a playlist of your favourite songs before you leave home to keep yourself entertained during your journey. ### Which airlines fly direct from Des Moines Intl. Airport (DSM) to San Diego Airport? > Operating 8 flights each month, Allegiant Air (G4) is a top choice when flying directly from DSM to San Diego Airport. ### Are DSM to SAN flight tickets cheaper when they're purchased at the last minute? > Booking your trip from Des Moines Intl. Airport to San Diego Airport at the last minute could be your ticket to a great deal. However, it might cost you a whole lot more! If you'd prefer not to take the risk, book well ahead of your departure date. In fact, Expedia has some of the best bargains as far ahead as 12 months in advance. If your preferred air carrier hasn't released tickets yet, check back frequently as deals are updated all the time on Expedia. ## Travel information | Origin airport | Des Moines Intl. | | --- | --- | | Destination airport | San Diego Intl. | | Airlines serving | Alaska Airlines | | Return price | £375 | | Distance | 2282 km | ## Book with confidence ### Compare flights from Des Moines to San Diego easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Des Moines to San Diego. Operating between them flights per day, 3 airlines cover the route. And fly direct, getting you to San Diego Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Des Moines Intl. to San Diego Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Des Moines Intl. (DSM) to San Diego Intl. (SAN) The easiest way to view the best deals on flights from Des Moines to San Diego today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Des Moines Intl. to San Diego Intl. start at just £375 and range up to £439.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Des Moines and San Diego - booking your flight during January, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Des Moines to San Diego flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Des Moines Intl. to San Diego Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Trending Routes - Trending Flights - Top Flights Destinations - Related Airlines - Cheap Flights from Other Airports - Expedia's Latest Trends ### Top Routes from Des Moines - [Des Moines to Melbourne (DSM - AVV)](https://expedia.co.uk/lp/flights/dsm/avv/des-moines-to-melbourne) - [Des Moines to Bristol (DSM - BRS)](https://expedia.co.uk/lp/flights/dsm/brs/des-moines-to-bristol) - [Des Moines to Tbilisi (DSM - TBS)](https://expedia.co.uk/lp/flights/dsm/tbs/des-moines-to-tbilisi) - [Des Moines to Honolulu (DSM - HNL)](https://expedia.co.uk/lp/flights/dsm/hnl/des-moines-to-honolulu) - [Des Moines to Dublin (DSM - DUB)](https://expedia.co.uk/lp/flights/dsm/dub/des-moines-to-dublin) - [Des Moines to London (DSM - LHR)](https://expedia.co.uk/lp/flights/dsm/lhr/des-moines-to-london) - [Des Moines to Atlanta (DSM - 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