Cheap Flights from La Mesa from £48

View £48 flight on Tue, 29 Dec 2026

Popular airlines from La Mesa

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  • Cheapest flights from La Mesa

    Prices were available within the past 7 days and start at £48 for one-way flights and £95 for return, for the period specified. Prices and availability are subject to change. Additional terms apply.

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    Select Alaska Airlines flight, departing Sat, 9 Jan from San Diego to San Francisco, returning Sat, 16 Jan, priced at £95 Found 1 day ago

    Sat, 9 Jan - Sat, 16 Jan · SFO · From £95 · Return

    Select American Airlines flight, departing Sat, 9 Jan from Carlsbad to San Francisco, returning Sat, 16 Jan, priced at £223 Found 1 day ago

    Sat, 9 Jan - Sat, 16 Jan · CLD · SFO · From £223 · Return

    Select American Airlines flight, departing Wed, 24 Feb from San Diego to Lima, returning Tue, 9 Mar, priced at £413 Found 5 days ago

    Wed, 24 Feb - Tue, 9 Mar · LIM · From £413 · Return

    Select American Airlines flight, departing Tue, 24 Nov from San Diego to Charlotte, returning Tue, 1 Dec, priced at £435 Found 1 day ago

    Tue, 24 Nov - Tue, 1 Dec · CLT · From £435 · Return

    Select American Airlines flight, departing Tue, 24 Nov from Carlsbad to Charlotte, returning Tue, 1 Dec, priced at £441 Found 1 day ago

    Tue, 24 Nov - T · ue, 1 Dec · CLD · CLT · From £441 · Return

    Select SAS flight, departing Mon, 11 Jan from San Diego to Helsinki, returning Sat, 16 Jan, priced at £514 Found 1 day ago

    Mon, 11 Jan - Sat, 16 Jan · HEL · From £514 · Return

    Select KLM flight, departing Tue, 1 Dec from San Diego to Catania, returning Mon, 7 Dec, priced at £526 Found 4 days ago

    Tue, 1 Dec - Mon, 7 Dec · CTA · From £526 · Return

    Select United flight, departing Mon, 10 May from San Diego to London, returning Wed, 12 May, priced at £564 Found 6 days ago

    Mon, 10 May - Wed, 12 May · LHR · From £564 · Return

    Select American Airlines flight, departing Wed, 22 Sept from Carlsbad to Lima, returning Wed, 29 Sept, priced at £666 Found 5 days ago

    Wed, 22 Sept - Wed, 29 Sept · CLD · LIM · From £666 · Return

    Select Air France flight, departing Sun, 14 Feb from San Diego to London, returning Fri, 19 Feb, priced at £669 Found 2 days ago

    Sun, 14 Feb - Fri, 19 Feb · LGW · From £669 · Return

    How to Find Cheap Flights from La Mesa

    How much is a flight from La Mesa?

    This week, flights from La Mesa are available between £95–£669.

    How to find cheap flights from La Mesa?

    Expedia makes it easy to compare cheap flights from La Mesa to many destinations. Check out excellent deals on both domestic and international flights from La Mesa. Once you select an offer, use our filters and sort by “ Price (Lowest)” to see the cheapest and most suitable options.

    How can I get the best deal on flights from La Mesa?

    Expedia gives you access to all the hottest deals on plane tickets so you can get the most amount of value for the lowest price possible. An excellent strategy for finding the best deal on flights is to be flexible with your dates. For each offer, you can compare prices for similar time frames using our “Show flexible dates” feature. Depending on your destination, direct flights from La Mesa may be more expensive. Airlines with strict bag policies or fees can also impact your costs.

    What is the best airline to fly from La Mesa?

    At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from La Mesa with: Alaska Airlines, American Airlines, JetBlue Airways, Aeromexico, KLM, Air Canada, SAS, United, Air France.

    What is the best month to fly from La Mesa?

    Prices on plane tickets vary considerably throughout the year due to seasonal demand. Historically, the cheapest time to buy flights from La Mesa airport(s) is January.

    When is the best time to book flights from La Mesa?

    ARC & Expedia Group historical data suggests that booking flights three weeks before departure and on a weekend, usually on a Sunday, can save you up to 20% on your fare. *

    Are there any last-minute flights from La Mesa?

    Expedia is the place to find last-minute flights from La Mesa, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source the best deals for you and display the best offers available over the next two weeks.

    Why book with Expedia?

    Booking flights from La Mesa with Expedia is the obvious choice to get low prices, save money and see more value for every pound spent. We show you the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from. You can customise your journey to your timeline, route preferences, budget, rewards programmes and more. Not only will you get a stellar deal, but you’ll also get rewards points back and the opportunity for additional discounts when bundling with a hotel or car hire.

    Can I change/cancel my flight?

    Some flights can be changed or cancelled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our customer service portal. We recommend choosing flights with no change fees for maximum flexibility. Filter by “Flexible change policies” to see flights with no change fees.

    Travel information

    Origin city nameSan Diego
    Origin airportSan Diego Intl. Airport
    Origin airport IATA codeSAN
    Airlines servingAlaska Airlines, American Airlines, Delta, United, Southwest Airlines, Frontier Airlines, JetBlue Airways, Air Canada, Lufthansa, British Airways, Japan Airlines, All Nippon Airways, Sun Country Airlines, Iberia, Korean Air, Finnair, KLM, Starlux Airlines, Brussels Airlines, WestJet, Aer Lingus, Cathay Pacific, Swiss International Air Lines, Air France, SAS, Qatar Airways, Austrian Airlines, Virgin Atlantic, China Airlines, LATAM Airlines Group, TAP Portugal, Copa, Malaysia Airlines, Turkish Airlines, Icelandair, Air Europa
    Popular airlineAlaska Airlines
    Return price£95

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