Title: Cheap Flights from La Mesa from £28 - Expedia.co.uk ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from La Mesa from £28 [View £28 flight on Thu, 16 Oct 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SAN,to:SFO,departure:16/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:27.30&airProductToken=AQowCi4IwaYBEgQzMzQzGJJoILJxKNvA-gIwycH6AjhYQABYAWoCU1ZyCEdIMk9BVkJOEgoIARABGAEqAkFTGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Hotels in La Mesa](https://expedia.co.uk/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[La Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesa.d8484.Car-Hire-Guide)[La Mesa Holidays](https://expedia.co.uk/La-Mesa.d8484.Holidays-City-Breaks) ## Popular airlines from La Mesa - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines - ![JetBlue Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_B6.svg) JetBlue Airways ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheapest flights from La Mesa These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Hawaiian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/HA.gif) Fri, 5 Dec - Mon, 15 Dec SAN San Diego SFO San Francisco £56 Return found 13 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:SFO,departure:05/12/2025TANYT&leg2=from:SFO,to:SAN,departure:15/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:55.70&airProductToken=AQoiCiAIyIIBEgQ2NTQwGJJoILJxKI_6_gIw-vr-AjhVQABYAQoiCiAIyIIBEgQ2NDU3GLJxIJJoKMXr_wIwouz_AjhVQABYARIKCAEQARgBKgJIQRgBIgQIARABKAQwAQ) ![Hawaiian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/HA.gif) Tue, 17 Feb - Tue, 3 Mar SAN San Diego LAS Las Vegas £57 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:LAS,departure:17/02/2026TANYT&leg2=from:LAS,to:SAN,departure:03/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:56.80&airProductToken=AQojCiEIyIIBEgQ2NDkxGJJoIIuQASiUtYUDMOS1hQM4VUAAWAEKIwohCMiCARIENjEzMxiLkAEgkmgoyNGGAzCJ0oYDOFVAAFgBEgoIARABGAEqAkhBGAEiBAgBEAEoBDAB) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Tue, 6 Jan - Wed, 21 Jan SAN San Diego LAS Las Vegas £57 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:LAS,departure:06/01/2026TANYT&leg2=from:LAS,to:SAN,departure:21/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:56.80&airProductToken=AQojCiEIxJgBEgQzNzQxGJJoIIuQASii4YEDMPrhgQM4RUAAWAEKIwohCMSYARIEMzc0MRiLkAEgkmgoy4eDAzCWiIMDOEVAAFgBEgoIARABGAEqAkRMGAEiBAgBEAEoBDAB) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Mon, 8 Dec - Tue, 16 Dec SAN San Diego DEN Denver £94 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:DEN,departure:08/12/2025TANYT&leg2=from:DEN,to:SAN,departure:16/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:93.40&airProductToken=AQowCi4IwaYBEgQzMDIxGJJoIINpKJqc_wIwo53_AjhYQABYAWoCU1ZyCE9IMk9BVkJOCjAKLgjBpgESBDE0MjgYg2kgkmgo9_T_AjCH9v8COFhAAFgBagJTVnIIR0gyT1hVQk4SCggBEAEYASoCQVMYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, 21 Oct - Wed, 22 Oct CLD Carlsbad LAS Las Vegas £117 Return found 11 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:CLD,to:LAS,departure:21/10/2025TANYT&leg2=from:LAS,to:CLD,departure:22/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:116.20&airProductToken=AQppCjIIwYIBEgQ0MDIyGOIaIO-5ASj7-PoCMMv5-gI4QkAAWAFqBUJBU0lDcghPVkFLWlNCVgozCMGCARIEMzAyMhjvuQEgi5ABKPv6-gIwy_v6AjhCQAFYAWoFQkFTSUNyCE9WQUtaU0JWCmkKMwjBggESBDE4MDgYi5ABIO-5ASighPsCMOiE-wI4QkAAWAFqBUJBU0lDcghPVkFLWlNCVgoyCMGCARIENDIyNRjvuQEg4hoogob7AjDThvsCOEJAAVgBagVCQVNJQ3IIT1ZBS1pTQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Sat, 1 Nov - Tue, 4 Nov SAN San Diego SEA Seattle £130 Return found 13 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:SEA,departure:01/11/2025TANYT&leg2=from:SEA,to:SAN,departure:04/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:129.90&airProductToken=AQovCi0IwaYBEgMzMzYYkmggkgEowvr7AjCA_PsCOFhAAFgBagJTVnIIT0gyRVhWQk4KLwotCMGmARIDNjk3GJIBIJJoKNWb_AIwgJ38AjhYQABYAWoCU1ZyCE9IMkVYVkJOEgoIARABGAEqAkFTGAEiBAgBEAEoAigDKAQwAQ) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Fri, 31 Oct - Tue, 4 Nov SAN San Diego PAE Seattle £138 Return found 13 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:PAE,departure:31/10/2025TANYT&leg2=from:PAE,to:SAN,departure:04/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:137.40&airProductToken=AQowCi4IwaYBEgQyMTU1GJJoII8gKOjv-wIwqPH7AjhYQABYAWoCU1ZyCFFIMkVBVkJOCjAKLgjBpgESBDIxNTQYjyAgkmgopJf8AjDOmPwCOFhAAFgBagJTVnIIT0gyRVhWQk4SCggBEAEYASoCQVMYASIECAEQASgCKAMoBDAB) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Sat, 25 Oct - Thu, 30 Oct SAN San Diego AUS Austin £160 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:AUS,departure:25/10/2025TANYT&leg2=from:AUS,to:SAN,departure:30/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:160.00&airProductToken=AQoxCi8IwaYBEgQzMjkyGJJoIICVASi6q_sCMPes-wI4WEAAWAFqAlNWcghPSDJPQVVCTgoxCi8IwaYBEgQzMjkzGICVASCSaCiU3fsCMNbe-wI4WEAAWAFqAlNWcghPSDJPQVVCThIKCAEQARgBKgJBUxgBIgQIARABKAIoAygEMAE) ![JetBlue Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/b6.gif) Fri, 26 Sept - Fri, 3 Oct SAN San Diego JFK New York £174 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:JFK,departure:26/09/2025TANYT&leg2=from:JFK,to:SAN,departure:03/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:174.00&airProductToken=AQovCi0IwmwSBDExOTAYkmggqVEovOb4AjCI6fgCOExAAFgBagJETnIIUEk0UVVFTDESCggBEAEYASoCQjYYASIECAEQASgCKAQoBjAB) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Thu, 30 Oct - Mon, 3 Nov SAN San Diego DFW Dallas £175 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SAN,to:DFW,departure:30/10/2025TANYT&leg2=from:DFW,to:SAN,departure:03/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:174.20&airProductToken=AQpfCi0IwaYBEgMzMzYYkmggkgEoguT7AjDA5fsCOFhAAFgBagJTVnIIR0gyT1pKQk4KLgjBpgESAzU0MhiSASCjsQEo7ub7AjDb6PsCOFhAAVgBagJTVnIIR0gyT1pKQk4KXwouCMGmARIDMzY1GKOxASCSASjIi_wCMNyN_AI4WEAAWAFqAlNWcghHSDJPWkpCTgotCMGmARIDNjIxGJIBIJJoKKaO_AIw14_8AjhYQAFYAWoCU1ZyCEdIMk9aSkJOEgoIARABGAEqAkFTGAEiBAgBEAEoAigDKAQwAQ) ## How to Find Cheap Flights from La Mesa #### How much is a flight from La Mesa?        This week, flights from La Mesa are available between £56–£175.  #### How to find cheap flights from La Mesa? Expedia makes it easy to compare cheap flights from La Mesa to many destinations. Check out excellent deals on both domestic and international flights from La Mesa. Once you select an offer, use our filters and sort by “Price (Lowest)” to see the cheapest and most suitable options.  #### How can I get the best deal on flights from La Mesa? Expedia gives you access to all the hottest deals on plane tickets so you can get the most amount of value for the lowest price possible. An excellent strategy for finding the best deal on flights is to be flexible with your dates. For each offer, you can compare prices for similar time frames using our “Show flexible dates” feature. Depending on your destination, direct flights from La Mesa may be more expensive. Airlines with strict bag policies or fees can also impact your costs.  #### What is the best airline to fly from La Mesa? At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from La Mesa with: Alaska Airlines, Delta, United, Hawaiian Airlines, American Airlines, JetBlue Airways.  #### What is the best month to fly from La Mesa? Prices on plane tickets vary considerably throughout the year due to seasonal demand. Historically, the cheapest time to buy flights from La Mesa airport(s) is December.  #### When is the best time to book flights from La Mesa? ARC & Expedia Group historical data suggests that booking flights three weeks before departure and on a weekend, usually on a Sunday, can save you up to 20% on your fare. \* #### Are there any last-minute flights from La Mesa? Expedia is the place to find last-minute flights from La Mesa, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source the best deals for you and display the best offers available over the next two weeks.  #### Why book with Expedia? Booking flights from La Mesa with Expedia is the obvious choice to get low prices, save money and see more value for every pound spent. We show you the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from. You can customise your journey to your timeline, route preferences, budget, rewards programmes and more. Not only will you get a stellar deal, but you’ll also get rewards points back and the opportunity for additional discounts when bundling with a hotel or car hire. #### Can I change/cancel my flight?  Some flights can be changed or cancelled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our customer service portal. We recommend choosing flights with no change fees for maximum flexibility. Filter by “Flexible change policies” to see flights with no change fees. \**Data specialists from both ARC and Expedia Group analyzed ARC’s global flight data to distill actionable information to help people save money on travel. While it’s impossible to guarantee when to find the lowest prices, after examining the variables, we were able to observe trends. Best day of the week to book and travel recommendation is based on average round-trip ticket prices for January through early October, for both 2019 and 2020, sourced from ARC’s global airline sales database.*. ## Travel information ## Flights from La Mesa: Essential Travel Information | Cheapest flight from La Mesa | £56 (roundtrip) | | --- | --- | | Best airlines to fly from La Mesa | Alaska Airlines, Delta, United, Hawaiian Airlines, American Airlines, JetBlue Airways | | Cheapest month to fly from La Mesa | December | | La Mesa IATA code | SAN | | La Mesa Country/State | California | | Airline ticket deals from La Mesa | £56 - £175 | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - [3 Star Hotels in Golden Hill](https://www.expedia.co.uk/3Star-Golden-Hill-San-Diego-Hotels.s30-n553248631819683100-0.Travel-Guide-Filter-Hotels) - [Hotels near Balboa Park](https://www.expedia.co.uk/Balboa-Park-Hotels.0-l507458-0.Travel-Guide-Filter-Hotels) - [Bostonia Hotels](https://www.expedia.co.uk/Bostonia-Hotels.d177696.Travel-Guide-Hotels) - 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