Title: Top Hotels in Wykoff | Reserve Now, Pay Later | Expedia.co.uk [Holiday Rentals in Wykoff](https://expedia.co.uk/Wykoff-Holiday-Rentals.d3000443967.Travel-Guide-HolidayRentals)[Wykoff Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Wykoff.d3000443967.Car-Hire-Guide)[Wykoff Holidays](https://expedia.co.uk/Wykoff.d3000443967.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Wykoff, MN from £41 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Wykoff Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=HOT_TUB) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=APARTMENT) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=POOL) ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Wykoff hotels and places to stay ![Front of property](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/78958ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft | 1 bedroom, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/aa7722ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/76c01c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/a69b6a55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Lodge inn Harmony 9.2/10 Wonderful (34) "Very friendly staff! Nice rooms that make you feel really comfortable." £106 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Harmony-Hotels-Country-Lodge-Inn.h104012904.Hotel-Information) ![Indoor pool, open 7:00 AM to 11:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/f1672741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | 1 bedroom, down duvets, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/7a5a17fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 11:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/401387bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/ce55c3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Trails Inn & Suites Preston 9.4/10 Exceptional (94) "Great desk host, nice property, comfortable rooms, nice breakfast & dining room within walking from Casey’s gas & market. " £104 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Preston-Hotels-Country-Trails-Inn-Suites.h100366373.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living area | TV, pay films](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/45535621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1652) "Great location, beautiful hotel!" £104 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Serves lunch, dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1063) "Great, inexpensive stay for mayo ..EXCELLENT STAFF!!" £63 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area Rochester 9.0/10 Wonderful (826) "All staff was friendly and the room and surroundings were clean." £54 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/daff149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/12906a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Rochester 7.2/10 Good (1003) "Thank you for a quick check in, beautiful and clean rooms. " £62 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/eabb718a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park 9.4/10 Exceptional (915) "Always stay here for my mayo visits " £92 includes taxes & fees 7 Nov - 8 Nov [](https://www.expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/13abbe0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/10494388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites Rochester 9.0/10 Wonderful (661) "Great stay, breakfast options could use some work but waffle was great. " £127 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/b2634691.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Double Room Single Use, 1 Bedroom, Kitchenette, River View | Private kitchenette | Coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/d5ae9d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/c4eab347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/c713cda3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Green Gables Inn Lanesboro 9.6/10 Exceptional (55) "The stay was wonderful and will definitely return. " £76 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Lanesboro-Hotels-Green-Gables-Inn.h114608460.Hotel-Information) ![Suite (Buffalo Bill Suite) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/80518cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/1021cb95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e0e6ae12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Crate Whirlpool Suite | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/f5dc5199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone Mill Hotel & Suites Lanesboro 9.2/10 Wonderful (646) "Beautiful and has lots of history " £84 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/34563649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South Rochester 9.4/10 Exceptional (204) "Check in was easy and staff was extremely helpful! We'll definitely stay here again. " £63 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/5f8bd693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/8cbdee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/c5b39a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/84709368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Rochester South Mayo Clinic Rochester 7.2/10 Good (79) "Nice hotel. Friendly staff and quiet. " £48 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/Rochester-Hotels-Extended-Stay-America-Suites-Rochester-South.h846574.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/05c87b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/5ef31f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handrails in stairways](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/be9b9262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/6d4c49ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### America's Stay Inn Stewartville Stewartville 8.0/10 Very good (405) "This place is kept immaculately clean. " [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Stay-Inn-Stewartville.h3395689.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | 1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester 8.8/10 Excellent (835) "Very convenient to Mayo clinic and good restaurants. " £69 includes taxes & fees 1 Nov - 2 Nov [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/745c7377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![16 bedrooms, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/24e0abff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South Rochester 9.6/10 Exceptional (226) "Great place" £98 includes taxes & fees 24 Oct - 25 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/28d8dcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/569ab236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic Rochester 8.4/10 Very good (1003) "A good place to stay." £73 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/bab1f0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/dd4123a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (Ground Floor) | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/46eaeea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Rochester Mayo Clinic Area Rochester 7.8/10 Good (1003) "Comfortable beds and good breakfast newspaper " £41 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/76e6edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/19467991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/fe70c541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/5419eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Rochester Mayo Clinic Area Rochester 7.0/10 Good (693) "Great place to stay close to places needed" £51 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Baymont-By-Wyndham-Rochester-Mayo-Clinic-Area.h459763.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/fca8e68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/c5c5f3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Select Rochester 8.4/10 Very good (1003) "Clean room | Staff was helpful and friendly" [](https://www.expedia.co.uk/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-014e984a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2555x4y4-921fa2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's Rochester 8.2/10 Very good (740) "staff was great no complaints room was phenomenal." £81 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels) ## Stay near popular Wykoff attractions [](https://www.expedia.co.uk/Eds-Museum-Hotels.0-l553248621532649595-0.Travel-Guide-Filter-Hotels) ### Ed's Museum You can spend time browsing the exhibits at Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532649595) ## Top Wykoff Hotel Reviews ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Thank you for a quick check in, beautiful and clean rooms. " [](https://expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](//images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Great, inexpensive stay for mayo ..EXCELLENT STAFF!!" [](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Spark by Hilton Rochester South](//images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Brand new everything was clean and working!" [](https://expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](//images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "We had a mix up on checking in and got a room someone was in. Staff corrected quickly and Merlin made it a fun experience to an error. The team could use more front desk help during peak check in times as the wait was 5 deep. " [](https://expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Nice hotel convenient for medical appointments ~ nice breakfast " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](//images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 10/10 Excellent "Very relaxing " [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](//images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Property was very accommodating for our needs. Staff was very friendly and helpful. Rooms were great! Lovely decor and roomy. Would highly recommend this establishment." [](https://expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Country Inn & Suites Rochester South Mayo Clinic](//images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83_y.jpg) ### Country Inn & Suites Rochester South Mayo Clinic 10/10 Excellent "Very easy to obtain a room and ease of checking in" [](https://expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Easy access to the Mayo Clinic. Nice dining options. Clean and reasonably updated. I always choose Kahler Grand because I feel safe there and it meets all of my needs." [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ## More cheap stays in Wykoff ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW, Rochester, MN £97 11 Oct - 12 Oct includes taxes & fees 8.6/10 Excellent! (1,001 reviews) [](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw, Rochester, MN £81 14 Oct - 15 Oct includes taxes & fees 8.2/10 Very Good! (740 reviews) [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Super 8 by Wyndham Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Rochester Mayo Clinic Area 106 SE 21st Street, 21st Street And Broadway, Rochester, MN £41 26 Oct - 27 Oct includes taxes & fees 7.6/10 Good! (1,002 reviews) [](https://expedia.co.uk/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw, Rochester, MN £62 19 Oct - 20 Oct includes taxes & fees 7.8/10 Good! (1,001 reviews) [](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway, Rochester, MN £67 8 Nov - 9 Nov includes taxes & fees 8.8/10 Excellent! (1,004 reviews) [](https://expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Rochester South - Mayo Area by IHG 4141 Maine Avenue SE, Rochester, MN £67 12 Oct - 13 Oct includes taxes & fees 8.6/10 Excellent! (1,000 reviews) [](https://expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Wykoff hotel for you. ### How can I save on a Wykoff hotel booking with Expedia? > Before booking your Wykoff hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Wykoff hotel? > Prices for hotels in Wykoff often vary, but you can find a great deal from £41 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [5 Star Hotels in Rochester](https://www.expedia.co.uk/5Star-Rochester-Hotels.s50-0-d3041.Travel-Guide-Filter-Hotels) - [Altura Hotels](https://www.expedia.co.uk/Altura-Hotels.d553248634983344337.Travel-Guide-Hotels) - [Brownsdale Hotels](https://www.expedia.co.uk/Brownsdale-Hotels.d3000348812.Travel-Guide-Hotels) - [Byron Hotels](https://www.expedia.co.uk/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels) - [Canton Hotels](https://www.expedia.co.uk/Canton-Hotels.d3000443033.Travel-Guide-Hotels) - [Dexter Hotels](https://www.expedia.co.uk/Dexter-Hotels.d3000443146.Travel-Guide-Hotels) - [Downtown Rochester Hotels](https://www.expedia.co.uk/Downtown-Rochester-Rochester-Hotels.0-n553248635976481217-0.Travel-Guide-Filter-Hotels) - [Eyota Hotels](https://www.expedia.co.uk/Eyota-Hotels.d3000348857.Travel-Guide-Hotels) - [Grand Meadow Hotels](https://www.expedia.co.uk/Grand-Meadow-Hotels.d3000348868.Travel-Guide-Hotels) - [Harmony Hotels](https://www.expedia.co.uk/Harmony-Hotels.d183425.Travel-Guide-Hotels) - [Hayfield Hotels](https://www.expedia.co.uk/Hayfield-Hotels.d3000348877.Travel-Guide-Hotels) - [Hotels near Jon Hassler Theater](https://www.expedia.co.uk/Jon-Hassler-Theater-Hotels.0-l6092539-0.Travel-Guide-Filter-Hotels) - [Kasson Hotels](https://www.expedia.co.uk/Kasson-Hotels.d6035256.Travel-Guide-Hotels) - [Lanesboro Hotels](https://www.expedia.co.uk/Lanesboro-Hotels.d183447.Travel-Guide-Hotels) - [Le Roy Hotels](https://www.expedia.co.uk/Le-Roy-Hotels.d3000443387.Travel-Guide-Hotels) - [Lewiston Hotels](https://www.expedia.co.uk/Lewiston-Hotels.d553248634983556152.Travel-Guide-Hotels) - [Mabel Hotels](https://www.expedia.co.uk/Mabel-Hotels.d3000443413.Travel-Guide-Hotels) - [Hotels near Mayo Clinic Hospital - Saint Marys Campus](https://www.expedia.co.uk/Mayo-Clinic-Hospital-Saint-Marys-Campus-Hotels.0-l6188928-0.Travel-Guide-Filter-Hotels) - [Hotels near Mayo Clinic](https://www.expedia.co.uk/Mayo-Clinic-Hotels.0-l6126906-0.Travel-Guide-Filter-Hotels) - [Peterson Hotels](https://www.expedia.co.uk/Peterson-Hotels.d553248633962922824.Travel-Guide-Hotels) - [Plainview Hotels](https://www.expedia.co.uk/Plainview-Hotels.d6195304.Travel-Guide-Hotels) - [Preston Hotels](https://www.expedia.co.uk/Preston-Hotels.d148239.Travel-Guide-Hotels) - [Racine Hotels](https://www.expedia.co.uk/Racine-Hotels.d553248634983342260.Travel-Guide-Hotels) - [Best Western Hotels in Rochester](https://www.expedia.co.uk/Rochester-Hotels-Best-Western.0-0-d3041--bBestWestern.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Rochester](https://www.expedia.co.uk/Rochester-Hotels-Gay-Friendly-Hotel.0-0-d3041-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Rochester](https://www.expedia.co.uk/Rochester-Hotels-Hotel-With-Early-Check-In.0-0-d3041-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Rochester](https://www.expedia.co.uk/Rochester-Hotels-Hotel-With-Free-Parking.0-0-d3041-thotelwithfreeparking.Travel-Guide-Filter-Hotels) - 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[Rose Creek Hotels](https://www.expedia.co.uk/Rose-Creek-Hotels.d3000348971.Travel-Guide-Hotels) - [Rushford Hotels](https://www.expedia.co.uk/Rushford-Hotels.d6298243.Travel-Guide-Hotels) - [Spring Valley Hotels](https://www.expedia.co.uk/Spring-Valley-Hotels.d602773.Travel-Guide-Hotels) - [St. Charles Hotels](https://www.expedia.co.uk/St-Charles-Hotels.d183431.Travel-Guide-Hotels) - [Stewartville Hotels](https://www.expedia.co.uk/Stewartville-Hotels.d183438.Travel-Guide-Hotels) - [Taopi Hotels](https://www.expedia.co.uk/Taopi-Hotels.d553248634983477966.Travel-Guide-Hotels) - [Flights to Rochester](https://www.expedia.co.uk/Cheap-Flights-To-Rochester.d3041.Travel-Guide-Flights) - [Flights from Rochester Intl.](https://www.expedia.co.uk/lp/airports/rst/flights-from-rochester-intl-airport) - [Flights from Harmony](https://www.expedia.co.uk/lp/flights/183425/flights-from-harmony) - [Flights from Stewartville](https://www.expedia.co.uk/lp/flights/183438/flights-from-stewartville) - [Flights from Le Roy](https://www.expedia.co.uk/lp/flights/3000443387/flights-from-le-roy) - [Flights from Rochester](https://www.expedia.co.uk/lp/flights/3041/flights-from-rochester) - [Flights from Peterson](https://www.expedia.co.uk/lp/flights/553248633962922824/flights-from-peterson) - [Flights from Aberdeen (ABR) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/abr/rst/aberdeen-to-rochester) - [Flights from Atlanta (ATL) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/atl/rst/atlanta-to-rochester) - [Flights from Hartford (BDL) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/bdl/rst/hartford-to-rochester) - [Flights from Birmingham (BHM) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/bhm/rst/birmingham-to-rochester) - [Flights from Birmingham (BHX) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/bhx/rst/birmingham-to-rochester) - [Flights from Bournemouth (BOH) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/boh/rst/bournemouth-to-rochester) - [Flights from Boston (BOS) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/bos/rst/boston-to-rochester) - 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[Flights from Liege (LGG) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/lgg/rst/liege-to-rochester) - [Flights from London (LHR) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/lhr/rst/london-to-rochester) - [Flights from Liverpool (LPL) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/lpl/rst/liverpool-to-rochester) - [Flights from Manchester (MAN) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/man/rst/manchester-to-rochester) - [Flights from Marseille (MRS) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/mrs/rst/marseille-to-rochester) - [Flights from Manitowoc (MTW) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/mtw/rst/manitowoc-to-rochester) - [Flights from Newcastle (NCL) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/ncl/rst/newcastle-to-rochester) - [Flights from Monterrey (NTR) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/ntr/rst/monterrey-to-rochester) - [Flights from Chicago (ORD) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/ord/rst/chicago-to-rochester) - [Flights from Oslo (OSL) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/osl/rst/oslo-to-rochester) - [Flights from Rockford (RFD) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/rfd/rst/rockford-to-rochester) - [Flights from Seattle (SEA) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/sea/rst/seattle-to-rochester) - [Flights from North Bay (YYB) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/yyb/rst/north-bay-to-rochester) - [Flights from Toronto (YYZ) to Rochester (RST)](https://www.expedia.co.uk/lp/flights/yyz/rst/toronto-to-rochester) - [Chatfield Holidays](https://www.expedia.co.uk/Chatfield.d183408.Holidays-City-Breaks) - [Visit Chatfield](https://www.expedia.co.uk/Chatfield.dx183408) - [Harmony Holidays](https://www.expedia.co.uk/Harmony.d183425.Holidays-City-Breaks) - [Visit Historic Southwest](https://www.expedia.co.uk/Rochester-Historic-Southwest.dx553248635976469790) - [Visit Rochester](https://www.expedia.co.uk/Rochester.dx3041) - [Spring Valley Holidays](https://www.expedia.co.uk/Spring-Valley.d602773.Holidays-City-Breaks) - 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