Title: Top-Rated Wykoff Hotels | Best Hotels in Wykoff 2026 - Expedia.co.uk [Holiday Rentals in Wykoff](https://expedia.co.uk/Wykoff-Holiday-Rentals.d3000443967.Travel-Guide-HolidayRentals)[Wykoff Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Wykoff.d3000443967.Car-Hire-Guide)[Wykoff Holidays](https://expedia.co.uk/Wykoff.d3000443967.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Wykoff Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=APARTMENT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=HOT_TUB) ## Check prices for these dates Tonight [26 Feb - 27 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-02-26&endDate=2026-02-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Feb - 28 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Wykoff hotels ![Front of property](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e0e6ae12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Boat Whirlpool Suite | Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/4d6c6c0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e13e365d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/80518cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone Mill Hotel & Suites [](https://www.expedia.co.uk/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) Lanesboro 9.2/10 Wonderful (666 reviews) "Great service, location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £83 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) ![Loft | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/aa7722ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/w1712h1283x2y0-ed421a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/78958ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/76c01c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Lodge inn [](https://www.expedia.co.uk/Harmony-Hotels-Country-Lodge-Inn.h104012904.Hotel-Information) Harmony 9.0/10 Wonderful (40 reviews) "Old motel but clean, with friendly owners." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fred £119 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Harmony-Hotels-Country-Lodge-Inn.h104012904.Hotel-Information) ![Deluxe Double Room | Down duvets, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/339ab71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/ce55c3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/84a5ef27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/de44ff5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Trails Inn & Suites [](https://www.expedia.co.uk/Preston-Hotels-Country-Trails-Inn-Suites.h100366373.Hotel-Information) Preston 9.4/10 Exceptional (104 reviews) "Great desk host, nice property, comfortable rooms, nice breakfast & dining room within walking from Casey’s gas & market. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy £103 includes taxes & fees 28 Feb - 1 Mar [](https://www.expedia.co.uk/Preston-Hotels-Country-Trails-Inn-Suites.h100366373.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/27999aed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/5ed80466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/567d427e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/c30d1af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites Spring Valley [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Best-Value-Inn-Suites-Spring-Valley.h856203.Hotel-Information) Spring Valley 8.2/10 Very good (439 reviews) "Attentive staff, clean room, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindy £72 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Best-Value-Inn-Suites-Spring-Valley.h856203.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/f7ac3cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed | Living area | LED TV](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/dc85cf59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/137ca358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/8bbae334.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White Valley Motel [](https://www.expedia.co.uk/Rochester-Hotels-White-Valley-Motel.h12333567.Hotel-Information) St. Charles 5.6/10 (129 reviews) "Very nice owner i wil come back again thank you.. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rolando £57 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Rochester-Hotels-White-Valley-Motel.h12333567.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/05c87b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/a2215e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/81bc0968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handrails in stairways](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/be9b9262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### America's Stay Inn Stewartville [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Stay-Inn-Stewartville.h3395689.Hotel-Information) Stewartville 8.0/10 Very good (426 reviews) "Good price, clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Stay-Inn-Stewartville.h3395689.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed | Living area | 40-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/5b3222d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/34563649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) Rochester 9.4/10 Exceptional (381 reviews) "Clean, quiet and a really nice place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony £58 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/52c02e28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/be8f1f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/d590e034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Rochester-South [](https://www.expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) Rochester 9.0/10 Wonderful (1,003 reviews) "Was a clean room that we had the hotel was quiet at night, friendly staff, and a very good breakfast buffet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry £67 includes taxes & fees 21 Mar - 22 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2557x4y0-117f61d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's [](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) Rochester 8.4/10 Very good (830 reviews) "Check in staff was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paulette £67 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/a0fb3319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/7f955511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/5cc7656e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/9d6e1a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Birch Hill Suite Rochester – Med City [](https://www.expedia.co.uk/Rochester-Hotels-Birch-Hill-Suite-Rochester-Med-City.h2784519.Hotel-Information) Rochester 7.6/10 Good (17 reviews) "Nice and quiet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana £51 includes taxes & fees 27 Feb - 28 Feb [](https://www.expedia.co.uk/Rochester-Hotels-Birch-Hill-Suite-Rochester-Med-City.h2784519.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/d5501184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/f083bd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/687d1b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Rochester South - Mayo Area by IHG [](https://www.expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) Rochester 8.8/10 Excellent (1,003 reviews) "Clean room, clean hotel, friendly staff Would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chee £70 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/317c9900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/e2eff1d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 11:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/80430d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/6c566811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Rochester South Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) Rochester 8.8/10 Excellent (1,003 reviews) "Clean rooms, friendly staff, good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Della £61 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/1a6136b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/adc84b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/76e5e57e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) Rochester 7.2/10 Good (1,040 reviews) "Everything was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara £62 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/a4d942ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) Rochester 9.0/10 Wonderful (943 reviews) "Very clean and staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £55 includes taxes & fees 20 Mar - 21 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/77987087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/4e4d3ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) Rochester 8.4/10 Very good (1,001 reviews) "Rooms are always clean wonderful service from the staff. It’s a great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamie £74 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Serves lunch, dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Patio Room, 1 King Bed, Pet-Friendly, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/079e9789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/4090d22a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing, Tub w/Grab bars) | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/f1759bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) Rochester 8.2/10 Very good (1,217 reviews) "Pleasant hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica £65 includes taxes & fees 21 Mar - 22 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Indoor pool, open 7:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/5e158908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/053999c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Double Beds, Poolside | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/w7013h4671x0y0-4efbd31a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Inn and Suites - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) Downtown Rochester 8.0/10 Very good (1,528 reviews) "The room was great! The staff was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bba1b373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | 1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) Downtown Rochester 8.8/10 Excellent (944 reviews) "Comfy beds, relatively quiet, great amenities, restaurant/bar is excellent as well. Always stay there when I have to stay in Rochester." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole £84 includes taxes & fees 14 Mar - 15 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/8ce1111a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/50ee7a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites [](https://www.expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) Downtown Rochester 8.8/10 Excellent (1,002 reviews) "Staff was very pleasant. Room was clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelley £96 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/38c15978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) Downtown Rochester 8.4/10 Very good (1,922 reviews) "Always an enjoyable place in a good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_3000443967) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels) ## Stay near popular Wykoff attractions ### Ed's Museum You can spend time browsing the exhibits at Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532649595) ## Top Wykoff Hotel Reviews ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg) ### Aspen Suites 10/10 Excellent "Very clean and nice. Staff was nice as well. Wish we would have stayed there last year. " [](https://expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg) ### Home2 Suites by Hilton Rochester Mayo Clinic Area 10/10 Excellent "Great clean space. Check in was a breeze. " [](https://expedia.co.uk/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Our stays with the Kahler Grand were tied to medical procedures at the Mayo Clinic. The staff understands Mayo is the reason the majority of guests are in Rochester. Everyone is kind, warm, and respectful. My husband and I want to acknowledge Salma who helped us extend our stay after our flight was cancelled last minute. She was both empathetic and professional. The hotel is above an easily accessed underground tunnel system of shops, restaurants, and connections to Mayo and other hospital building shuttle stops." [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Staff were very friendly, entire space was exceptionally clean, and the pool and the hot tub were some of the best maintained that I have seen. 10-10 experience. " [](https://expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 10/10 Excellent "Clea" [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "The room was very nice-bed and pillows were comfortable. Really loved the access to the Skywalk, this was a large feature for us and one that will influence our decision to stay there again in the future! " [](https://expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "It was nice and clean" [](https://expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Nice clean rooms. We had a couple requests and they were very accommodating for us. Definitely will stay there again. " [](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "Was not the original place I thought we were staying at but were pleasantly surprized. Nice, clean, great staff. Close to the hospital. Would definitely recommend and stay there again. " [](https://expedia.co.uk/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ## More cheap stays in Wykoff ![Super 8 by Wyndham Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Rochester Mayo Clinic Area 106 SE 21st Street Rochester MN £45 21 Mar - 22 Mar includes taxes & fees 7.8/10 Good! (1,001 reviews) [](https://expedia.co.uk/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Econo Lodge Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Mayo Clinic Area 1850 S Broadway Rochester MN £55 20 Mar - 21 Mar includes taxes & fees 9/10 Wonderful! (943 reviews) [](https://expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw Rochester MN £64 24 Mar - 25 Mar includes taxes & fees 7.8/10 Good! (1,001 reviews) [](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway Rochester MN £67 21 Mar - 22 Mar includes taxes & fees 9/10 Wonderful! (1,003 reviews) [](https://expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw Rochester MN £67 2 Mar - 3 Mar includes taxes & fees 8.4/10 Very Good! (830 reviews) [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW Rochester MN £96 1 Mar - 2 Mar includes taxes & fees 8.8/10 Excellent! (1,002 reviews) [](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Wykoff? > Wykoff is a compact village, and the main street, Gold Street, runs through its heart. Here you'll find the local businesses, including a few small shops and the community's primary restaurant. The village hall and a local park are also situated centrally, making everything easily accessible on foot. > > > For families, staying in the village centre is convenient because it keeps you close to the few amenities Wykoff offers. The local park provides a space for children to play, and being near the restaurant simplifies meal times. It's a quiet setting, ideal for a relaxed stay. > > > Couples looking for a peaceful getaway will also appreciate the village centre. Its tranquil nature and the availability of a local eatery mean you can enjoy a calm break without needing to travel far. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Wykoff hotel booking with Expedia? ### How much is the nightly rate at a Wykoff hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [5 Star Hotels in Rochester ](https://www.expedia.co.uk/5Star-Rochester-Hotels.s50-0-d3041.Travel-Guide-Filter-Hotels) - [Altura Hotels ](https://www.expedia.co.uk/Altura-Hotels.d553248634983344337.Travel-Guide-Hotels) - [Brownsdale Hotels ](https://www.expedia.co.uk/Brownsdale-Hotels.d3000348812.Travel-Guide-Hotels) - [Byron Hotels ](https://www.expedia.co.uk/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels) - [Canton Hotels ](https://www.expedia.co.uk/Canton-Hotels.d3000443033.Travel-Guide-Hotels) - [Dexter Hotels ](https://www.expedia.co.uk/Dexter-Hotels.d3000443146.Travel-Guide-Hotels) - 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