Title: Hotels in Wykoff, MN - Best Wykoff Hotels from £46 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Wykoff](https://expedia.co.uk/Wykoff-Holiday-Rentals.d3000443967.Travel-Guide-HolidayRentals)[Wykoff Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Wykoff.d3000443967.Car-Hire-Guide)[Wykoff Holidays](https://expedia.co.uk/Wykoff.d3000443967.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Wykoff, MN from £46 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Wykoff Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=APARTMENT) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=CABIN) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=PETS) ## Check prices for these dates Tonight [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000443967&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Wykoff hotels ![Front of property](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e0e6ae12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e13e365d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/80518cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/3fb15b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone Mill Hotel & Suites [](https://www.expedia.co.uk/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) Lanesboro 9.2/10 Wonderful (663 reviews) "Great service, location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £84 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) ![Deluxe Double Room | Down duvets, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/339ab71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/84a5ef27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/81b58091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/ce55c3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Trails Inn & Suites [](https://www.expedia.co.uk/Preston-Hotels-Country-Trails-Inn-Suites.h100366373.Hotel-Information) Preston 9.4/10 Exceptional (102 reviews) "Great desk host, nice property, comfortable rooms, nice breakfast & dining room within walking from Casey’s gas & market. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy £94 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Preston-Hotels-Country-Trails-Inn-Suites.h100366373.Hotel-Information) ![Loft | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/aa7722ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/w1712h1283x2y0-ed421a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/78958ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/a69b6a55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Lodge inn [](https://www.expedia.co.uk/Harmony-Hotels-Country-Lodge-Inn.h104012904.Hotel-Information) Harmony 9.0/10 Wonderful (39 reviews) "Old motel but clean, with friendly owners." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fred £120 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Harmony-Hotels-Country-Lodge-Inn.h104012904.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/f7ac3cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room (2 Double Beds) | Desk, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/9f23656a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed | Living area | LED TV](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/dc85cf59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/13000000/12340000/12333600/12333567/8bbae334.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### White Valley Motel [](https://www.expedia.co.uk/Rochester-Hotels-White-Valley-Motel.h12333567.Hotel-Information) St. Charles 5.6/10 (128 reviews) "Very nice owner i wil come back again thank you.. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rolando £57 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rochester-Hotels-White-Valley-Motel.h12333567.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/27999aed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/c30d1af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/656cf808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/567d427e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites Spring Valley [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Best-Value-Inn-Suites-Spring-Valley.h856203.Hotel-Information) Spring Valley 8.2/10 Very good (435 reviews) "The place was very clean, very quiet and the staff was extremely helpful. We will be back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa £73 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Best-Value-Inn-Suites-Spring-Valley.h856203.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/34563649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/86a7bf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) Rochester 9.4/10 Exceptional (344 reviews) "Very good accommodations at a wonderful price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £63 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/d590e034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/52c02e28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/be8f1f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Rochester-South [](https://www.expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) Rochester 9.0/10 Wonderful (1,005 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randall £67 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/d5501184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/fd6d967e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/687d1b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Rochester South - Mayo Area by IHG [](https://www.expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) Rochester 8.8/10 Excellent (1,002 reviews) "Clean room, clean hotel, friendly staff Would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chee £63 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/05c87b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handrails in stairways](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/be9b9262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/a2215e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/81bc0968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### America's Stay Inn Stewartville [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Stay-Inn-Stewartville.h3395689.Hotel-Information) Stewartville 8.0/10 Very good (420 reviews) "Room was nicer and furnished better than most high end places I’ve stayed at. It’s a small hotel on a busy road, but comfortable bed and clean." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Robert [](https://www.expedia.co.uk/Rochester-Hotels-Americas-Stay-Inn-Stewartville.h3395689.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bba1b373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | 1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) Downtown Rochester 8.8/10 Excellent (904 reviews) "Clean room and friendly staff! Great breakfast at restaurant as well!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor £69 includes taxes & fees 24 Jan - 25 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/d78e621e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/85d1ed51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 11:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/be097c9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/f5c13843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Rochester South Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) Rochester 8.8/10 Excellent (1,003 reviews) "Enjoyed our stay, rated breakfast as a erage as we did not try it." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeanne £65 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) Rochester 9.0/10 Wonderful (914 reviews) "Staff were awesome. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Damon £57 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/76e5e57e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/1a6136b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) Rochester 7.2/10 Good (1,025 reviews) "Staff was courteous and breakfast was well stocked." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug £61 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/56e8351b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/9314117f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/25614355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/37670f4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Rochester Downtown, MN [](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) Downtown Rochester 8.8/10 Excellent (859 reviews) "Transportation services very good staff very helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joyce £92 includes taxes & fees 30 Jan - 31 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/05e87cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) Downtown Rochester 8.4/10 Very good (1,857 reviews) "Beautiful hotel with a lot of history." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Serves lunch, dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing, Tub w/Grab bars) | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/f1759bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/4090d22a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/96cfed25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) Rochester 8.2/10 Very good (1,169 reviews) "Room clean, staff nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry £66 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/1f96e8b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/c820f144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/aaa1bd90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/28200/28184/1a68c6fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Quality-Inn-Suites-Mayo-Clinic-Area.h28184.Hotel-Information) Rochester 8.8/10 Excellent (839 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £57 includes taxes & fees 23 Jan - 24 Jan [](https://www.expedia.co.uk/Rochester-Hotels-Quality-Inn-Suites-Mayo-Clinic-Area.h28184.Hotel-Information) ![Indoor pool, open 7:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Double Beds, Poolside | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/w7013h4671x0y0-4efbd31a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/053999c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/26c9439d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Inn and Suites - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) Downtown Rochester 8.0/10 Very good (1,525 reviews) "Clean room, good room service and good breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/6fafab53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4c2060a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/8ad9f7f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) Kutzky Park 7.8/10 Good (1,002 reviews) "The people are very helpful and kind." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynn £64 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/4e4d3ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/937e22b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) Rochester 8.4/10 Very good (1,002 reviews) "Very friendly staff; clean, comfortable room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen £79 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-24&endDate=2026-01-25®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels) ## Stay near popular Wykoff attractions ### Ed's Museum You can spend time browsing the exhibits at Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532649595) ## Top Wykoff Hotel Reviews ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "No free breakfast " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Clean room and friendly staff! Great breakfast at restaurant as well!" [](https://expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 10/10 Excellent "Great room. Very clean ! Very very nice lady at check-in!!" [](https://expedia.co.uk/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Nice place to stay. No hot breakfast though only Complimentary breakfast offered. " [](https://expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "Great clean and friendly hotel. Rooms were spacious and had a notably nice smell when you first walk in. " [](https://expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 10/10 Excellent "LOVE this hotel. We stay every time we go to Mayo. It is out dated but SUPER CLEAN, a place you can tell employees take pride in. We always recognize staff even through the years. Everyone is always helpful and kind. Great breakfast as well. One huge perk too is it has access in the hotel to the subway system. Thanks Brentwood for another awesome stay, you never disappoint. " [](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07_y.jpg) ### The Berkman 10/10 Excellent "It was a bit tricky finding our area we could park in but it worked out. " [](https://expedia.co.uk/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Friendly staff and very clean " [](https://expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Clean big room close to the Mayo " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ## More cheap stays in Wykoff ![Super 8 by Wyndham Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Rochester Mayo Clinic Area 106 SE 21st Street Rochester MN £46 16 Jan - 17 Jan includes taxes & fees 7.6/10 Good! (1,000 reviews) [](https://expedia.co.uk/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Econo Lodge Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Mayo Clinic Area 1850 S Broadway Rochester MN £57 16 Jan - 17 Jan includes taxes & fees 9/10 Wonderful! (912 reviews) [](https://expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw Rochester MN £64 11 Jan - 12 Jan includes taxes & fees 7.8/10 Good! (1,007 reviews) [](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway Rochester MN £67 1 Feb - 2 Feb includes taxes & fees 9/10 Wonderful! (1,006 reviews) [](https://expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw Rochester MN £81 14 Jan - 15 Jan includes taxes & fees 8.2/10 Very Good! (798 reviews) [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW Rochester MN [Get rates](https://expedia.co.uk/Hotel-Search?startDate=24%2F01%2F2026&endDate=25%2F01%2F2026&selected=10007613&PinnedHotelID=10007613&HadPinnedHotel=true®ionId=3000443967) 8.8/10 Excellent! (1,006 reviews) [](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Wykoff hotel booking with Expedia? ### How much is the nightly rate at a Wykoff hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [5 Star Hotels in Rochester ](https://www.expedia.co.uk/5Star-Rochester-Hotels.s50-0-d3041.Travel-Guide-Filter-Hotels) - [Altura Hotels ](https://www.expedia.co.uk/Altura-Hotels.d553248634983344337.Travel-Guide-Hotels) - [Brownsdale Hotels ](https://www.expedia.co.uk/Brownsdale-Hotels.d3000348812.Travel-Guide-Hotels) - [Byron Hotels ](https://www.expedia.co.uk/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels) - [Canton Hotels ](https://www.expedia.co.uk/Canton-Hotels.d3000443033.Travel-Guide-Hotels) - [Dexter Hotels ](https://www.expedia.co.uk/Dexter-Hotels.d3000443146.Travel-Guide-Hotels) - 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