Title: Hotels in Worthington, MO - Best Worthington Hotels from £45 - Fully Refundable Options - Expedia.co.uk

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## Go beyond your typical stay in Worthington

Pet friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=Worthington%2C+Missouri%2C+United+States+of+America&regionId=553248634983347772&latLong=40.40836%2C-92.688806&adults=2&startDate=2026-04-15&d1=2026-04-15&endDate=2026-04-17&d2=2026-04-17&amenities=PETS)

## Check prices for these dates

Tonight

[1 Apr - 2 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[2 Apr - 3 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2026-04-02&endDate=2026-04-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Worthington hotels

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/d203c711.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/08bb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/9c660a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Kirksville-University Area

[](https://www.expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

Kirksville

9.0/10

Wonderful

(177 reviews)

"The room was very clean. Check-in was super fast, and check-out was even faster. The location is excellent. For dinner we walked next door to Colton’s Steakhouse. The breakfast was good with plenty of variety. I would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca

£55

includes taxes & fees

23 Apr - 24 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/8a5baebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/w1021h682x0y0-c9b85e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Non Smoking | Down duvets, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/7d76c669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/1e205061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Kirksville

[](https://www.expedia.co.uk/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

Kirksville

7.6/10

Good

(400 reviews)

"Nice place."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Keith

£67

includes taxes & fees

5 Apr - 6 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/4be7f63c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/f363e21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/ee47dad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

[](https://www.expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

Kirksville

9.2/10

Wonderful

(525 reviews)

"Excellent service and stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Taylor

£109

includes taxes & fees

4 Apr - 5 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/c19d4fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/68baa0ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Refrigerator & Microwave | Hypo-allergenic bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/de278a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Kirksville

[](https://www.expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

Kirksville

9.2/10

Wonderful

(604 reviews)

"Great place to stay with friendly staff and clean rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Binu

£112

includes taxes & fees

16 Apr - 17 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Superior Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/b428c708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/fe067a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/33e2a913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/661e3930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Kirksville University Area

[](https://www.expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information)

Kirksville

7.6/10

Good

(903 reviews)

"Great stay. Only negative was the dirty roll away bed sheet. Great breakfast and super staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aime

£54

includes taxes & fees

13 Apr - 14 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information)

![Desk, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/a7e2219f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/bathtub, free toiletries, towels](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/7f07ee5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9afc2091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/e004f75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Knights Inn Kirksville

[](https://www.expedia.co.uk/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

Kirksville

7.2/10

Good

(251 reviews)

"Room was clean… quiet… "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

£53

includes taxes & fees

3 Apr - 4 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f4cdd5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f3c5f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/2180aea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Kirksville

[](https://www.expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

Kirksville

6.6/10

(1,001 reviews)

"We booked this room- but we did not end up staying due to several issues and concerns we had with the property condition and cleanliness. Staff was understanding and did not charge us for our stay. We appreciated that very much. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thea

£54

includes taxes & fees

16 Apr - 17 Apr

[](https://www.expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/2000000/1420000/1410900/1410833/bb8d2309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1420000/1410900/1410833/f30d1f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1420000/1410900/1410833/a9cf2503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1410900/1410833/037d52fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Budget Host Village Inn

[](https://www.expedia.co.uk/Macon-Hotels-Budget-Host-Village-Inn.h1410833.Hotel-Information)

Kirksville

6.0/10

(126 reviews)

"It was a great place to stay. It’s right next to restaurants that you could just walk to them."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Landon

£45

includes taxes & fees

1 May - 2 May

[](https://www.expedia.co.uk/Macon-Hotels-Budget-Host-Village-Inn.h1410833.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Worthington Hotel Reviews

![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

8/10 Good

"Staff was very helpful and courteous. Parking was abundant and safe."

[](https://expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/c19d4fbf_y.jpg)

### Hampton Inn Kirksville

10/10 Excellent

"So spacious and get food!!"

[](https://expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Country's Edge Retreat](https://images.trvl-media.com/lodging/121000000/120070000/120065000/120064921/59962910_y.jpg)

### Country's Edge Retreat

10/10 Excellent

"The home was very clean, spacious, comfortable and had everything we needed. The host was wonderful, very friendly and even checked in to see if we needed anything. I'd definitely stay here again."

[](https://expedia.co.uk/Greentop-Hotels-Countrys-Edge-Retreat.h120064921.Hotel-Information)

![Base Camp Cottage](https://images.trvl-media.com/lodging/112000000/111840000/111833600/111833563/c8a88b56_y.jpg)

### Base Camp Cottage

10/10 Excellent

"Clean and cozy "

[](https://expedia.co.uk/Kirksville-Hotels-Base-Camp-Cottage.h111833563.Hotel-Information)

![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6_y.jpg)

### Super 8 by Wyndham Kirksville-University Area

4/10 Poor

"4:pm Went in rang bell 4 times, no response. Called got message machine. Finally another person walks in and rings bell. Manager Patel walks in goes straight by me and goes to coffee machine, fills up his coffee then casually walks around me and decides to acknowledge my presents. You can see it was recently remodeled but based on from desk area it won’t be long before it goes downhill."

[](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Zeke’s Retreat – Hunter’s Getaway with On-Site Taxidermy Shop](https://images.trvl-media.com/lodging/120000000/119160000/119156700/119156645/1a68972a_y.jpg)

### Zeke’s Retreat – Hunter’s Getaway with On-Site Taxidermy Shop

10/10 Excellent

"Perfect fit for our work trip"

[](https://expedia.co.uk/Zekes-Retreat-Hunters-Getaway-With-On-Site-Taxidermy-Shop.h119156645.Hotel-Information)

![Country Cabin In The Woods](https://images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg)

### Country Cabin In The Woods

10/10 Excellent

"The cabin never disappoints. Highly recommend. Hope to stay there again soon."

[](https://expedia.co.uk/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information)

![Knights Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/e004f75c_y.jpg)

### Knights Inn Kirksville

2/10 Terrible

"This actually shows a 8.2 which is more like a 2.8 it says continual breakfast and there is none!! It is a pass through room and both doors had gaps around them you could actually see outside. Stains above both beds no cover on exhaust fan in bathroom and did not work had a Walmart bag stuffed in the vent, smoke detector had not battery and door was broke on it. Had a nice frig but no way to plug it into a three pin outlet unless you took it to the bathroom. Heating/A/C unit was green with mold. With all that said the room and bed was clean but cold as crap especially when it got -7 outside. Paid for three nights could not handle the room did not even stay the last night in fear of freezing to death. Save yourself a headache and go some where else!!!"

[](https://expedia.co.uk/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](https://images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/f734b584_y.jpg)

### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville

10/10 Excellent

"Everything was excellent!"

[](https://expedia.co.uk/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information)

## More cheap stays in Worthington

![Baymont by Wyndham Kirksville University Area](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/b428c708_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Baymont by Wyndham Kirksville University Area

2702 South Franklin Kirksville MO

£54

13 Apr - 14 Apr

includes taxes & fees

7.6/10 Good! (903 reviews)

[](https://expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information)

![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Super 8 by Wyndham Kirksville-University Area

1101 Country Club Dr Kirksville MO

£55

23 Apr - 24 Apr

includes taxes & fees

9/10 Wonderful! (177 reviews)

[](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/8a5baebb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn Kirksville

2209 N. Baltimore Street Kirksville MO

£67

5 Apr - 6 Apr

includes taxes & fees

[](https://expedia.co.uk/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information)

![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

2523 South Franklin St. Kirksville MO

£109

4 Apr - 5 Apr

includes taxes & fees

9.2/10 Wonderful! (525 reviews)

[](https://expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/c19d4fbf_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Kirksville

2604 N. Baltimore Street Kirksville MO

£112

16 Apr - 17 Apr

includes taxes & fees

9.2/10 Wonderful! (604 reviews)

[](https://expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Thousand Hills](https://images.trvl-media.com/lodging/107000000/106800000/106792500/106792431/855824fb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Thousand Hills

20431 Missouri 157 Kirksville MO

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=15%2F04%2F2026&endDate=16%2F04%2F2026&selected=106792431&PinnedHotelID=106792431&HadPinnedHotel=true&regionId=553248634983347772)

9/10 Wonderful! (14 reviews)

[](https://expedia.co.uk/Kirksville-Hotels-Thousand-Hills.h106792431.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in Worthington?

> This area is the heart of Worthington, offering a mix of historic buildings, local shops, and restaurants. It's very walkable, with many amenities within a short stroll. You'll find Worthington's central square, often hosting community events, right in the middle of this district.
> 
>   
> For couples looking for a relaxed yet engaging stay, Downtown is ideal. You can spend your days exploring independent boutiques, enjoying meals at various eateries, and perhaps catching a live performance at the local theatre. The evening strolls through the well-lit streets offer a pleasant end to the day.
> 
>   
> Solo travellers will also appreciate the convenience and community feel of Downtown. With numerous cafes and easy access to local parks, it's simple to find a spot to relax or to join in with local activities.

### When is the best time to go to Worthington?

> These periods offer the most pleasant weather, with comfortable temperatures and less humidity than the peak summer months. It's ideal for enjoying outdoor activities like exploring the Worthington Lake State Park or taking a leisurely stroll through the historic downtown area without the intensity of summer heat. You'll also find the natural scenery particularly appealing during these times, especially the autumn foliage.
> 
>   
> For those looking to avoid crowds and potentially find better value on accommodation, visiting just outside the main tourist season in late April or early November can be a good option.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Worthington hotel booking with Expedia?

### How much is the nightly rate at a Worthington hotel?

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- [Visit Eagleville ](https://www.expedia.co.uk/Eagleville.dx3000444843)
- [Visit Excello ](https://www.expedia.co.uk/Excello.dx3000444873)
- [Gibbs Holidays ](https://www.expedia.co.uk/Gibbs.d3000444924.Holidays-City-Breaks)
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- [Visit Jamesport ](https://www.expedia.co.uk/Jamesport.dx6361320)
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- [La Plata Holidays ](https://www.expedia.co.uk/La-Plata.d55790.Holidays-City-Breaks)
- [Lake Thunderhead ](https://www.expedia.co.uk/Lake-Thunderhead-Unionville.d665709839042408448.Attraction)
- [Visit Marceline ](https://www.expedia.co.uk/Marceline.dx55821)
- [Mark Twain Casino ](https://www.expedia.co.uk/Mark-Twain-Casino-La-Grange.d553248621561876918.Attraction)
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- [Visit Moberly ](https://www.expedia.co.uk/Moberly.dx8708)
- [Visit Monroe City ](https://www.expedia.co.uk/Monroe-City.dx8694)
- [Visit Northeast Missouri ](https://www.expedia.co.uk/Northeast-Missouri.dx6058818)

- [Car hire in Budget Carrer De Can Rius 16-18, Llevant ](https://www.expedia.co.uk/Budget-at-Carrer-De-Can-Rius-16-18.v102383.Car-Rental-Guide-Location)
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- [Ok Mobility Rental Cars in Northeast Missouri ](https://www.expedia.co.uk/OK-Mobility-Car-Rentals-In-Northeast-Missouri.d6058818-c1057.Car-Rental-Guide-Suppliers)

- [Holliday Holiday Rentals ](https://www.expedia.co.uk/Holliday-Holiday-Rentals.d6318422.Travel-Guide-HolidayRentals)

- [Things to do in Northeast Missouri ](https://www.expedia.co.uk/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities)

- [Book Hotels in Worthington on Expedia.com ](https://www.expedia.com/Worthington-Hotels.d553248634983347772.Travel-Guide-Hotels)

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