Title: Hotels in Worthington, MO - Best Worthington Hotels from £55 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Worthington](https://expedia.co.uk/Worthington-Holiday-Rentals.d553248634983347772.Travel-Guide-HolidayRentals)[Worthington Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Worthington.d553248634983347772.Car-Hire-Guide)[Worthington Holidays](https://expedia.co.uk/Worthington.d553248634983347772.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Worthington, MO from £55 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983347772&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Worthington hotels ![Room, 2 Double Beds, Non Smoking | Pillow-top beds, desk, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/4afe2a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/fd2e50c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/d203c711.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Kirksville-University Area [](https://www.expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) Kirksville 9.0/10 Wonderful (149) "The rooms were clean and the breakfast bar is outstanding staff was very friendly and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bill £55 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/8218b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/0822c1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator & Microwave | Hypo-allergenic bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/3ced37b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kirksville [](https://www.expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) Kirksville 9.2/10 Wonderful (574) "Clean and very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £102 includes taxes & fees 10 Jan - 11 Jan 2026 [](https://www.expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/35d9f717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/26642d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/781fda5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Kirksville - University Area by IHG [](https://www.expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) Kirksville 9.2/10 Wonderful (510) "Excellent service and stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Taylor £94 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/fa987a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, towels](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/cf6ce139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9b5928a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Desk, free cots/infant beds, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/b5263971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Kirksville [](https://www.expedia.co.uk/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information) Kirksville 7.2/10 Good (250) "Cozy and cool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lois £57 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f3c5f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/093bb3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/59d144bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Kirksville [](https://www.expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) Kirksville 6.6/10 (1000) "Breakfast was great enjoyed the pool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dara £55 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06®ionId=553248634983347772&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWorthington-Hotels.d553248634983347772.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWorthington-Hotels.d553248634983347772.Travel-Guide-Hotels) ## Top Worthington Hotel Reviews ![Country's Edge Retreat](https://images.trvl-media.com/lodging/121000000/120070000/120065000/120064921/58c67ab5_y.jpg) ### Country's Edge Retreat 10/10 Excellent "We love Country’s Edge Retreat. It is spotless, and so comfortably decorated. It has everything you need, including a beautiful yard, a grill and beautiful deck with plenty of seating and beautiful lights. We love sitting out there and visiting. The beds are super comfy and soft, with wonderful linens. The kitchen has all that you need, incuding an island for extra space. A wonderful place to stay." [](https://expedia.co.uk/Greentop-Hotels-Countrys-Edge-Retreat.h120064921.Hotel-Information) ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg) ### Super 8 by Wyndham Kirksville-University Area 10/10 Excellent "Good value. Quiet" [](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![New tiny home in an incredible private setting among all nature has to offer.](https://images.trvl-media.com/lodging/118000000/117030000/117029100/117029091/2899d4ac_y.jpg) ### New tiny home in an incredible private setting among all nature has to offer. 10/10 Excellent "The host was extremely welcoming and communicated well. They had a stocked kitchen for us with food and coffee. " [](https://expedia.co.uk/Kirksville-Hotels-New-Tiny-Home-In-An-Incredible-Private-Setting-Among-All-Nature-Has-To-Offer.h117029091.Hotel-Information) ![Rescued Wood Bunkhouse-Sleeps 8 hunters. Full kitchen and bath. Lots of parking.](https://images.trvl-media.com/lodging/111000000/110440000/110437900/110437864/69c801dd_y.jpg) ### Rescued Wood Bunkhouse-Sleeps 8 hunters. Full kitchen and bath. Lots of parking. 8/10 Good "Honestly could not have asked for a better host. He's a really nice guy and was very helpful and responsive when i had questions. All amenities were prepared for the stay. House is older and could be cleaner, but is in the process of being remodeled but was not expecting much more as the house served its purpose for my stay. Will be returning in the future." [](https://expedia.co.uk/Rescued-Wood-Bunkhouse-Sleeps-8-Hunters-Full-Kitchen-And-Bath.h110437864.Hotel-Information) ![Home in the Heart of Kirksville](https://images.trvl-media.com/lodging/104000000/103100000/103097400/103097370/1c70daa1_y.jpg) ### Home in the Heart of Kirksville 10/10 Excellent "The house was very clean and the owner very responsive to any questions we had. They thought of everything in the home, from snacks, coffee, creamer, etc. We were in town for our son’s wedding and were in and out of the house for a couple days. We enjoyed our stay!" [](https://expedia.co.uk/Kirksville-Hotels-Home-In-The-Heart-Of-Kirksville.h103097370.Hotel-Information) ![Thousand Hills](https://images.trvl-media.com/lodging/107000000/106800000/106792500/106792431/855824fb_y.jpg) ### Thousand Hills 10/10 Excellent "Room was in great shape and close to actities I did" [](https://expedia.co.uk/Kirksville-Hotels-Thousand-Hills.h106792431.Hotel-Information) ![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](https://images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/acd401ea_y.jpg) ### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville 10/10 Excellent "A lot of old homes that are not well taken care of. " [](https://expedia.co.uk/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information) ![Base Camp Cottage](https://images.trvl-media.com/lodging/112000000/111840000/111833600/111833563/aa1f0009_y.jpg) ### Base Camp Cottage 10/10 Excellent "This house was perfect for my family to stay in. Our family was having a reunion in Thousand Hills State Park and this was just a short drive away. I SO appreciated that there were a few little toys for my kids to play with. The house had everything we needed and was very clean. Would definitely recommend! " [](https://expedia.co.uk/Kirksville-Hotels-Base-Camp-Cottage.h111833563.Hotel-Information) ![Country Cabin In The Woods](https://images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg) ### Country Cabin In The Woods 10/10 Excellent "The cabin was a great get away from the town. Very remote and peaceful cabin. Very clean. Could have used some brighter lighting. It was difficult to play games at the kitchen table after sunset. Thank you!!!" [](https://expedia.co.uk/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information) ## More cheap stays in Worthington ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Kirksville-University Area 1101 Country Club Dr Kirksville MO £55 1 Jan - 2 Jan 2026 includes taxes & fees 9/10 Wonderful! (148 reviews) [](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Kirksville 3805 S Baltimore St Kirksville MO £55 25 Dec - 26 Dec includes taxes & fees 6.6/10 (999 reviews) [](https://expedia.co.uk/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 2523 South Franklin St. Kirksville MO £94 11 Jan - 12 Jan 2026 includes taxes & fees 9.2/10 Wonderful! (510 reviews) [](https://expedia.co.uk/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Kirksville 2604 N. Baltimore Street Kirksville MO £102 10 Jan - 11 Jan 2026 includes taxes & fees 9/10 Wonderful! (571 reviews) [](https://expedia.co.uk/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Baymont by Wyndham Kirksville University Area](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Kirksville University Area 2702 South Franklin Kirksville MO [Get rates](https://expedia.co.uk/Hotel-Search?startDate=05%2F01%2F2026&endDate=06%2F01%2F2026&selected=125458&PinnedHotelID=125458&HadPinnedHotel=true®ionId=553248634983347772) 7.6/10 Good! (900 reviews) [](https://expedia.co.uk/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Kirksville 2209 N Baltimore St Kirksville MO [Get rates](https://expedia.co.uk/Hotel-Search?startDate=05%2F01%2F2026&endDate=06%2F01%2F2026&selected=20482&PinnedHotelID=20482&HadPinnedHotel=true®ionId=553248634983347772) 7.4/10 Good! (394 reviews) [](https://expedia.co.uk/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Worthington? ### What are some of the best holiday rentals that Worthington has to offer? ### If I need to cancel my hotel reservation in Worthington, will I receive a refund? ### What is staying in Worthington like? ### What should I do while I'm visiting Worthington? ### What's the seasonal weather in Worthington? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Spa Hotels in Bethany ](https://www.expedia.co.uk/Bethany-Hotels-Spa-Hotels.0-0-d6897-tSpaHotels.Travel-Guide-Filter-Hotels) - [Brookfield Hotels ](https://www.expedia.co.uk/Brookfield-Hotels.d55605.Travel-Guide-Hotels) - [Callao Hotels ](https://www.expedia.co.uk/Callao-Hotels.d3000444667.Travel-Guide-Hotels) - [Hotels near Crowder State Park ](https://www.expedia.co.uk/Crowder-State-Park-Hotels.0-l553248622800802661-0.Travel-Guide-Filter-Hotels) - 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