Title: TOP Luxury Hotels in Vendicari Natural Reserve for 2025 - Vendicari Natural Reserve Upscale Hotels | Expedia.co.uk [Vendicari Natural Reserve Travel Guide](https://expedia.co.uk/Vendicari-Natural-Reserve.dx6182494)[Hotels in Vendicari Natural Reserve](https://expedia.co.uk/Vendicari-Natural-Reserve-Hotels.d6182494.Travel-Guide-Hotels)[Holiday Rentals in Vendicari Natural Reserve](https://expedia.co.uk/Vendicari-Natural-Reserve-Holiday-Rentals.d6182494.Travel-Guide-HolidayRentals)[Flights to Vendicari Natural Reserve](https://expedia.co.uk/Cheap-Flights-To-Vendicari-Natural-Reserve.d6182494.Travel-Guide-Flights)[Vendicari Natural Reserve Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Vendicari-Natural-Reserve.d6182494.Car-Hire-Guide)[Vendicari Natural Reserve Holidays](https://expedia.co.uk/Vendicari-Natural-Reserve.d6182494.Holidays-City-Breaks) ![Spiaggia di Cala Mosche. One of the many slightly hidden beaches of south-eastern Sicily](https://images.trvl-media.com/place/6034839/b859b779-e22e-4f36-91ce-29a600d3857b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Matthew Thode # Find luxury hotels in Vendicari Natural Reserve - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Vendicari Natural Reserve Luxury Hotels Tonight [9 Nov - 10 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2025-11-09&endDate=2025-11-10&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [10 Nov - 11 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2025-11-10&endDate=2025-11-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2025-11-21&endDate=2025-11-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Vendicari Natural Reserve Luxury Hotels ## Top Vendicari Natural Reserve Hotel Reviews ![Algila' Ortigia Charme Hotel](//images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "Can't say enough great things about Algila! The staff was so helpful & accommodating, awesome location, nice rooms and large common areas to gather aft" [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Grand Hotel Ortigia Siracusa](//images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f_y.jpg) ### Grand Hotel Ortigia Siracusa 10/10 Excellent "breakfast was good" [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Palazzo Artemide - VRetreats](//images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg) ### Palazzo Artemide - VRetreats 10/10 Excellent "Very courteous staff. Excellent location close to everything. Room was modern and clean. Highly recommend." [](https://expedia.co.uk/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Grand Hotel Des Ètrangers - The Leading Hotels of the World](//images.trvl-media.com/lodging/1000000/980000/976400/976389/c9e03ff2_y.jpg) ### Grand Hotel Des Ètrangers - The Leading Hotels of the World 10/10 Excellent "Great hotel and saff" [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information) ![Eureka Palace Hotel Spa Resort](//images.trvl-media.com/lodging/4000000/3820000/3814900/3814820/af67d93f_y.jpg) ### Eureka Palace Hotel Spa Resort 10/10 Excellent "OK" [](https://expedia.co.uk/Syracuse-Hotels-Eureka-Palace-Hotel-Spa-Resort.h3814820.Hotel-Information) ![Grande Albergo Alfeo](//images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/2465bcdb_y.jpg) ### Grande Albergo Alfeo 10/10 Excellent "Great location very walkable. Staff was pleasant and breakfast was plentiful and tasty. Stay here again." 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