Ustupu Island Holidays from £548

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The Latest Ustupu Island Holiday Packages

Price found within the past 48 hours. Click for updated prices.
  • A pool area with lounge chairs, umbrellas, and a bridge over the water.
    27 Dec - 2 Jan

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen Airport
    6 nights
    4.0 star property
    8.6/10 - Excellent (1,823 reviews)
    Return • Georgetown (GEO) - Panama City (PTY)
    GEO - PTY • 1 stop PTY - GEO • 1 stop
    £952
    £548
    per traveller
    found 12 hours ago
    Riande Aeropuerto Hotel & Casino
  • A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
    27 Dec - 2 Jan

    Megapolis Hotel Panamá + Flight

    San Francisco
    6 nights
    4.5 star property
    8.6/10 - Excellent (1,835 reviews)
    "Asked for a pharmacy and they didn’t know or just didn’t want to give info. There were three just on the other side of the building and 24 hours"
    Reviewed November 3, 2026
    Return • Georgetown (GEO) - Panama City (PTY)
    GEO - PTY • 1 stop PTY - GEO • 1 stop
    £1,767
    £804
    per traveller
    found 12 hours ago
    Megapolis Hotel Panamá
  • A multi-story building with balconies, arched windows, and decorative railings.
    28 Dec - 30 Dec

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    2 nights
    4.0 star property
    9.2/10 - Wonderful (1,000 reviews)
    "Ac worked great."
    Reviewed November 2, 2026
    Return • Kingston (KIN) - Panama City (PTY)
    KIN - PTY • Direct PTY - KIN • Direct
    £1,219
    £631
    per traveller
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
    27 Dec - 2 Jan

    Hotel Riu Plaza Panama + Flight

    Bella Vista
    6 nights
    5.0 star property
    9.0/10 - Wonderful (6,177 reviews)
    Return • Georgetown (GEO) - Panama City (PTY)
    GEO - PTY • 1 stop PTY - GEO • 1 stop
    £1,099
    £687
    per traveller
    found 12 hours ago
    Hotel Riu Plaza Panama
  • A modern building with a glass facade, a curved structure, and a flat roof.
    27 Dec - 2 Jan

    Decapolis Hotel Panama City + Flight

    San Francisco
    6 nights
    4.0 star property
    8.6/10 - Excellent (1,725 reviews)
    "We always stay there and have a good experience, good breakfast and very nice staff"
    Reviewed November 2, 2026
    Return • Georgetown (GEO) - Panama City (PTY)
    GEO - PTY • 1 stop PTY - GEO • 1 stop
    £941
    £608
    per traveller
    found 12 hours ago
    Decapolis Hotel Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.