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Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Uptown Greenville hotels

A modern hotel with a stone facade, large windows, and a well-lit entrance.

1. Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (175 reviews)
"Really nice and new hotel."
United States
Sharon
The price is £116
includes taxes & fees
25 Oct - 26 Oct
Hilton Garden INN Greenville University
A circular fire pit with seating around it, a covered patio area, and a brick building in the background.

2. Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
1.5 mi from Uptown Greenville
9.2 out of 10, Wonderful, (443 reviews)
"We love the amazing staff and this well maintained location!"
United States
Joy
The price is £98
includes taxes & fees
1 Nov - 2 Nov
Homewood Suites By Hilton Greenville, NC
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a wardrobe.

3. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
1.5 mi from Uptown Greenville
8.4 out of 10, Very good, (1,002 reviews)
"The staff was fantastic!!"
United States
Alicia
The price is £95
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Greenville by IHG
A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

4. Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
1.4 mi from Uptown Greenville
9.2 out of 10, Wonderful, (381 reviews)
"Pool at this property Will be great"
United States
Ashly
The price is £103
includes taxes & fees
1 Nov - 2 Nov
Staybridge Suites Greenville Medical Center by IHG
An outdoor patio area with a fire pit, seating, and umbrellas.

5. Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
1.5 mi from Uptown Greenville
8.8 out of 10, Excellent, (539 reviews)
"The facilities were clean and quiet and the breakfast was good."
United States
Steve
The price is £108
includes taxes & fees
1 Nov - 2 Nov
Residence Inn by Marriott Greenville
A multi-story hotel with a covered entrance, large windows, and a brick facade.

6. Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
2.0 star property
1.6 mi from Uptown Greenville
7.0 out of 10, Good, (1,001 reviews)
"Property was convenient and staff made the stay very enjoyable. Wasn't the cleaners place but room was very clean. Again staff was great!! Also parking and food very close and good"
United States
Samuel
The price is £54
includes taxes & fees
1 Nov - 2 Nov
Microtel Inn & Suites by Wyndham Greenville/University Medic
A Courtyard by Marriott hotel with a covered entrance, outdoor seating, and a landscaped area.

7. Courtyard Marriott Greenville

Courtyard Marriott Greenville
3.0 star property
Medical District, 1.7 mi from Uptown Greenville
8.8 out of 10, Excellent, (948 reviews)
"The rooms were clean, and the staff was outstanding. I enjoyed my stay and will visit again."
United States
Wanda
The price is £101
includes taxes & fees
1 Nov - 2 Nov
Courtyard Marriott Greenville
A table set with glassware, plates, and cutlery, and a person arranging the table settings.

8. Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 2.7 mi from Uptown Greenville
8.8 out of 10, Excellent, (1,001 reviews)
"Great place, comfortable rooms"
United States
Jonathan
The price is £82
includes taxes & fees
21 Oct - 22 Oct
Holiday Inn Greenville by IHG
A modern dining area with a large window, a chandelier, and a patterned sofa.

9. Quality Inn Greenville near University

Quality Inn Greenville near University
2.5 star property
1.3 mi from Uptown Greenville
7.4 out of 10, Good, (1,002 reviews)
"Execelente"
United States
Gerson
The price is £61
includes taxes & fees
8 Nov - 9 Nov
Quality Inn Greenville near University
An indoor swimming pool with clear markings, a "NO DIVING" sign, and a view of parked cars outside.

10. Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
3.0 star property
1.5 mi from Uptown Greenville
8.6 out of 10, Excellent, (511 reviews)
"Clean room and nice breakfast!"
United States
Frank
The price is £110
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Greenville
A hotel room with a desk, two beds, a sofa, a TV, and a coffee machine.

11. Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
2.4 mi from Uptown Greenville
9.0 out of 10, Wonderful, (1,000 reviews)
"Had a great stay of 4 days"
United States
Thomas
The price is £97
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Suites-Greenville
A hotel entrance with a sign reading 'Candlewood Suites.' There are potted plants and a mailbox in the foreground.

12. Candlewood Suites Greenville NC by IHG

Candlewood Suites Greenville NC by IHG
2.5 star property
2.9 mi from Uptown Greenville
8.4 out of 10, Very good, (675 reviews)
"Staff was excellent"
United States
scott
The price is £75
includes taxes & fees
1 Nov - 2 Nov
Candlewood Suites Greenville NC by IHG
A hotel entrance with a prominent 'Super 8' sign, brick facade, and potted plants.

13. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
1.4 mi from Uptown Greenville
6.6 out of 10, (613 reviews)
"Great location and friendly staff"
United States
Sharlene
The price is £56
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Greenville
An outdoor patio with seating, potted plants, and a brick fireplace.

14. Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 2.6 mi from Uptown Greenville
9.0 out of 10, Wonderful, (681 reviews)
"This is a great property. I use it on repeat for business trips."
United States
tina
The price is £113
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Greenville
A hotel room with two beds, each with patterned bedding, a bedside table with a lamp, and a framed picture on the wall.

15. Motel 6 Greenville, NC – ECU-Medical Center

Motel 6 Greenville, NC – ECU-Medical Center
2.0 star property
1.4 mi from Uptown Greenville
6.4 out of 10, (134 reviews)
"Immediately walking to the room, a roach was on the wall, a roach in the refrigerators and the bathroom was next t that clean and presentable. It was a last minute booking abs a game in the area so most hotels were already sold out. I won’t book there again."
United States
Tomeka
The price is £62
includes taxes & fees
18 Oct - 19 Oct
Motel 6 Greenville, NC – ECU-Medical Center
A spacious lobby with a blue sofa, yellow armchairs, a central coffee table, and a wooden balcony railing.

16. Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
3 mi from Uptown Greenville
8.6 out of 10, Excellent, (557 reviews)
"Location was comfortable and close to event"
United States
Raymond
The price is £94
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn & Suites Greenville Near East Carolina University
A spacious lobby with a high ceiling, a large window, a ceiling fan, a brown leather sofa, a glass coffee table with flowers, a patterned rug, and a red carpet.

17. Econo Lodge Greenville near University

Econo Lodge Greenville near University
2.0 star property
1.4 mi from Uptown Greenville
7.2 out of 10, Good, (477 reviews)
"Nice place, is great for a whole family, close to beaches."
United States
Gerardo
The price is £65
includes taxes & fees
20 Oct - 21 Oct
Econo Lodge Greenville near University
An outdoor patio with seating, a fire pit, and string lights.

18. Hilton Greenville

Hilton Greenville
4.0 star property
Convention District, 2.8 mi from Uptown Greenville
8.8 out of 10, Excellent, (580 reviews)
"Best hotel in Greenville when you can’t get the place downtown!"
United States
Sara
The price is £133
includes taxes & fees
25 Oct - 26 Oct
Hilton Greenville
A compact living space with a kitchenette, a dining area, and a seating area with a sofa and a coffee table.

19. Affordable Suites Greenville

Affordable Suites Greenville
2.0 star property
2.4 mi from Uptown Greenville
8.4 out of 10, Very good, (683 reviews)
"Not bad, no frills. A cheaper option near the university"
United States
John
The price is £60
includes taxes & fees
9 Nov - 10 Nov
Affordable Suites Greenville
A clean, well-lit room with a tiled floor, a counter with a cash register, and a sign detailing room rates and policies.

20. Economy Inn of Greenville, NC

Economy Inn of Greenville, NC
2.5 star property
1.3 mi from Uptown Greenville
4.4 out of 10, (119 reviews)
"I GOT NONE SMOKING ROOM.. SMELL BAD SO I WANTED MY MONEY HE SAID NO REFUND. COME FIND ITS DRUG MOTEL I WILL DO EVERYTHING N MY POWER GET THAT MOTEL CLOSE DOWN PLACE NEED BE BULL DOZIER OVER"
United States
Walter
The price is £48
includes taxes & fees
15 Nov - 16 Nov
Economy Inn of Greenville, NC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Uptown Greenville

Find the best Uptown Greenville areas for the activities you enjoy most.

University District

While University District isn't home to many top sights, Dowdy–Ficklen Stadium and Williams Arena at Minges Coliseum are some notable places to visit nearby.

Convention District

When in Convention District, you can plan a visit to University Commons and 11 Galleria, some noteworthy sights in the nearby area.

Medical District

If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and South Greenville Park.

Westhaven

Westhaven might not have many top sights, but 11 Galleria and University Commons are two attractions nearby that you can check out.

Greenville Heights

If you're looking for some top things to see and do in Greenville Heights and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium.

Top Uptown Greenville Hotel Reviews

Hampton Inn Greenville

Hampton Inn Greenville

10/10 Excellent
"This is a great property. I use it on repeat for business trips."
tina 1-night trip
Posted 10 hours ago
Hampton Inn Greenville

Frequently asked questions

What are the best family hotels in Uptown Greenville?
For an excellent family stay in Uptown Greenville, consider the Hilton Garden INN Greenville University.

The 3-star Hilton Garden Inn Greenville University, with an outstanding 9.4 rating, is a superb choice for families. This hotel offers complimentary cribs and connecting rooms, which are very convenient for larger families. It is located in a historical and shopping district, making it easy to explore. Guests will appreciate the on-site gift shops or newsstand and a grocery or convenience store for any family needs. The hotel is also very close to Town Common, just 0.5 km away, providing a pleasant area for families to relax.
What are the top pet-friendly hotels in Uptown Greenville?
For a highly-rated pet-friendly hotel in Uptown Greenville, consider the Hilton Garden INN Greenville University.

This 3-star hotel, with an impressive 9.4 rating, warmly welcomes pets, making it an excellent choice for travellers with animal companions. It is conveniently located in a historical district, close to a shopping district, and has a museum nearby. Guests will find a gift shop or newsstand on-site, as well as a grocery and convenience store for any necessities. The hotel is also just 0.5 km from Town Common, offering easy access to a pleasant green space.
What are the best budget hotels in Uptown Greenville?
For a budget-friendly and highly-rated hotel in Uptown Greenville, consider the Hilton Garden INN Greenville University.

The 3-star Hilton Garden Inn Greenville University, with an impressive 9.4 rating, offers a comfortable stay with excellent amenities. It is conveniently located in a historical and shopping district, with a museum nearby. Guests can enjoy complimentary WiFi and the convenience of a gift shop or newsstand, as well as a grocery or convenience store on-site. The hotel is also well-situated for exploring local attractions, being just 0.5 km from Town Common.
When is the best time to go to Uptown Greenville?
The best time to go to Uptown Greenville is during the spring (April to May) and autumn (September to October) months.

During these periods, the weather is pleasantly mild with comfortable temperatures, making it ideal for exploring the city's outdoor attractions and enjoying events. You'll find fewer humid days compared to summer, and the natural beauty of North Carolina is on full display, especially the autumn foliage.

For those interested in university activities, visiting in late spring or early autumn allows you to experience the buzz of East Carolina University without the peak summer heat.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Uptown Greenville.
How much is the nightly rate at a Uptown Greenville hotel?
Hotel prices in Uptown Greenville often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.