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Check prices for these dates

This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

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Our top choices for Uptown Greenville hotels

Exterior

1. Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (161 reviews)
"Best hotel in Greenville with a good restaurant in a great bar."
United States
Mark
The price is £101
includes taxes & fees
20 Sept - 21 Sept
Hilton Garden INN Greenville University
Exterior

2. Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
2.0 star property
1.6 mi from Uptown Greenville
7.0 out of 10, Good, (1,018 reviews)
"Wonderful staff"
United States
Hipolito
The price is £56
includes taxes & fees
13 Sept - 14 Sept
Microtel Inn & Suites by Wyndham Greenville/University Medic
Exterior

3. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
1.5 mi from Uptown Greenville
8.4 out of 10, Very good, (1,000 reviews)
"Breakfast was top class...Probably the best place we ate on the whole vacation. Nice rooms, nice staff...excellent place to stay"
United States
Tim
The price is £91
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express Greenville by IHG
Terrace/patio

4. Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
1.5 mi from Uptown Greenville
9.2 out of 10, Wonderful, (407 reviews)
"It's the next best thing to your comfy home."
United States
William-Karla
The price is £94
includes taxes & fees
3 Sept - 4 Sept
Homewood Suites By Hilton Greenville, NC
Lobby

5. Quality Inn Greenville near University

Quality Inn Greenville near University
2.5 star property
1.3 mi from Uptown Greenville
7.4 out of 10, Good, (1,010 reviews)
"Nice place 👍"
United States
Dereck
The price is £63
includes taxes & fees
14 Sept - 15 Sept
Quality Inn Greenville near University
Terrace/patio

6. Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
1.5 mi from Uptown Greenville
8.8 out of 10, Excellent, (527 reviews)
"The facilities were clean and quiet and the breakfast was good."
United States
Steve
The price is £95
includes taxes & fees
27 Aug - 28 Aug
Residence Inn by Marriott Greenville
Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (with Sofabed) | In-room safe, desk, blackout curtains, iron/ironing board

7. Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
2.4 mi from Uptown Greenville
9.0 out of 10, Wonderful, (1,015 reviews)
"Great stay"
United States
Ezekiel
The price is £93
includes taxes & fees
31 Aug - 1 Sept
Best Western Plus Suites-Greenville
Indoor pool

8. Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
3.0 star property
1.5 mi from Uptown Greenville
8.6 out of 10, Excellent, (504 reviews)
"Clean room and nice breakfast!"
United States
Frank
The price is £108
includes taxes & fees
29 Aug - 30 Aug
Fairfield Inn & Suites by Marriott Greenville
Exterior

9. Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
1.4 mi from Uptown Greenville
9.2 out of 10, Wonderful, (356 reviews)
"Awesome Stay !!"
United States
Levi
The price is £94
includes taxes & fees
30 Aug - 31 Aug
Staybridge Suites Greenville Medical Center by IHG
Lobby

10. Econo Lodge Greenville near University

Econo Lodge Greenville near University
2.0 star property
1.4 mi from Uptown Greenville
7.2 out of 10, Good, (462 reviews)
"Nice place, is great for a whole family, close to beaches."
United States
Gerardo
The price is £60
includes taxes & fees
30 Aug - 31 Aug
Econo Lodge Greenville near University
View from property

11. Courtyard Marriott Greenville

Courtyard Marriott Greenville
3.0 star property
Medical District, 1.7 mi from Uptown Greenville
8.8 out of 10, Excellent, (932 reviews)
"Great hospitality"
United States
Quentin
The price is £105
includes taxes & fees
30 Aug - 31 Aug
Courtyard Marriott Greenville
Exterior

12. Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 2.7 mi from Uptown Greenville
8.8 out of 10, Excellent, (1,011 reviews)
"great place to stay"
United States
Bridget
The price is £75
includes taxes & fees
23 Sept - 24 Sept
Holiday Inn Greenville by IHG
Free WiFi, bed sheets

13. Motel 6 Greenville, NC – ECU-Medical Center

Motel 6 Greenville, NC – ECU-Medical Center
2.0 star property
1.4 mi from Uptown Greenville
6.6 out of 10, (130 reviews)
"I like that the bed had good covering. Not just a thin sheet and AC worked wonderfully."
United States
Renee
The price is £60
includes taxes & fees
2 Sept - 3 Sept
Motel 6 Greenville, NC – ECU-Medical Center
Lobby

14. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
1.4 mi from Uptown Greenville
6.6 out of 10, (604 reviews)
"Great place to stay"
United States
ShaQuita
The price is £68
includes taxes & fees
13 Sept - 14 Sept
Super 8 by Wyndham Greenville
Terrace/patio

15. Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 2.6 mi from Uptown Greenville
9.0 out of 10, Wonderful, (660 reviews)
"The rooms were very clean and spacious. The hot breakfast was delicious and plentiful. Nice hotel."
United States
Judy
The price is £99
includes taxes & fees
6 Sept - 7 Sept
Hampton Inn Greenville
Lobby

16. Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
3 mi from Uptown Greenville
8.8 out of 10, Excellent, (530 reviews)
"Clean property, helpful and friendly staff, and wonderful breakfast."
United States
Kendall
The price is £91
includes taxes & fees
6 Sept - 7 Sept
Comfort Inn & Suites Greenville Near East Carolina University
Basic Double Room | Free WiFi, bed sheets

17. Affordable Suites Greenville

Affordable Suites Greenville
2.0 star property
2.4 mi from Uptown Greenville
8.4 out of 10, Very good, (667 reviews)
"Staff is very helpful and courteous."
United States
Noman
The price is £57
includes taxes & fees
14 Sept - 15 Sept
Affordable Suites Greenville
Exterior

18. Candlewood Suites Greenville NC by IHG

Candlewood Suites Greenville NC by IHG
2.5 star property
2.9 mi from Uptown Greenville
8.4 out of 10, Very good, (659 reviews)
"Nice accommodations, staff was very friendly, could use a little updating."
United States
Amanda
The price is £81
includes taxes & fees
13 Sept - 14 Sept
Candlewood Suites Greenville NC by IHG
Lobby

19. Economy Inn of Greenville, NC

Economy Inn of Greenville, NC
2.5 star property
1.3 mi from Uptown Greenville
4.4 out of 10, (116 reviews)
"That's the worst place I've ever stayed"
United States
David
The price is £47
includes taxes & fees
26 Aug - 27 Aug
Economy Inn of Greenville, NC
Lobby

20. Red Roof Inn Greenville, NC

Red Roof Inn Greenville, NC
2.0 star property
2.1 mi from Uptown Greenville
4.8 out of 10, (286 reviews)
"N/A"
United States
Orlando
The price is £53
includes taxes & fees
30 Aug - 31 Aug
Red Roof Inn Greenville, NC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Uptown Greenville

Find the best Uptown Greenville areas for the activities you enjoy most.

University District

While University District isn't home to many top sights, Dowdy–Ficklen Stadium and Williams Arena at Minges Coliseum are some notable places to visit nearby.

Convention District

When in Convention District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area.

Medical District

If you're looking for some top things to see and do in Medical District and surrounding area, you can visit North Pines and Arlington Crossing.

Westhaven

Westhaven might not have many top sights, but 11 Galleria and Williams Arena at Minges Coliseum are two attractions nearby that you can check out.

A cityscape with a dense forest in the foreground and a clear blue sky.

College View Historic District

If you're looking for some top things to see and do in College View Historic District and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium.

Top Uptown Greenville Hotel Reviews

Hampton Inn Greenville

Hampton Inn Greenville

10/10 Excellent
"The rooms were very clean and spacious. The hot breakfast was delicious and plentiful. Nice hotel."
Judy 1-night trip
Posted 11 hours ago
Hampton Inn Greenville

Frequently asked questions

What are the best family hotels in Uptown Greenville?
For an excellent family stay in Uptown Greenville, consider the Hilton Garden INN Greenville University.

The 3-star Hilton Garden Inn Greenville University, with an outstanding 9.4 rating, is a superb choice for families. This hotel offers complimentary cribs and connecting rooms, which are very convenient for larger families. It is located in a historical and shopping district, making it easy to explore. Guests will appreciate the on-site gift shops or newsstand and a grocery or convenience store for any family needs. The hotel is also very close to Town Common, just 0.5 km away, providing a pleasant area for families to relax.
What are the top pet-friendly hotels in Uptown Greenville?
For a highly-rated pet-friendly hotel in Uptown Greenville, consider the Hilton Garden INN Greenville University.

This 3-star hotel, with an impressive 9.4 rating, warmly welcomes pets, making it an excellent choice for travellers with animal companions. It is conveniently located in a historical district, close to a shopping district, and has a museum nearby. Guests will find a gift shop or newsstand on-site, as well as a grocery and convenience store for any necessities. The hotel is also just 0.5 km from Town Common, offering easy access to a pleasant green space.
What are the best budget hotels in Uptown Greenville?
For a budget-friendly and highly-rated hotel in Uptown Greenville, consider the Hilton Garden INN Greenville University.

The 3-star Hilton Garden Inn Greenville University, with an impressive 9.4 rating, offers a comfortable stay with excellent amenities. It is conveniently located in a historical and shopping district, with a museum nearby. Guests can enjoy complimentary WiFi and the convenience of a gift shop or newsstand, as well as a grocery or convenience store on-site. The hotel is also well-situated for exploring local attractions, being just 0.5 km from Town Common.
When is the best time to go to Uptown Greenville?
The best time to go to Uptown Greenville is during the spring (April to May) and autumn (September to October) months.

During these periods, the weather is pleasantly mild with comfortable temperatures, making it ideal for exploring the city's outdoor attractions and enjoying events. You'll find fewer humid days compared to summer, and the natural beauty of North Carolina is on full display, especially the autumn foliage.

For those interested in university activities, visiting in late spring or early autumn allows you to experience the buzz of East Carolina University without the peak summer heat.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Uptown Greenville.
How much is the nightly rate at a Uptown Greenville hotel?
Hotel prices in Uptown Greenville often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.