Title: The Best Hotels in Uptown Greenville, Greenville - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Greenville](https://expedia.co.uk/Greenville-Holiday-Rentals.d2779.Travel-Guide-HolidayRentals)[Flights to Greenville](https://expedia.co.uk/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Uptown Greenville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Uptown-Greenville.d908648619872518144.Car-Hire-Guide)[Uptown Greenville Holidays](https://expedia.co.uk/Uptown-Greenville.d908648619872518144.Holidays-City-Breaks) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [18 Jan - 19 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=908648619872518144&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Jan - 20 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=908648619872518144&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=908648619872518144&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=908648619872518144&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Uptown Greenville hotels ![Exterior](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3840h2556x0y4-0c33f88e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w2557h3836x3y4-828357d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-c0bc68bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden INN Greenville University [](https://www.expedia.co.uk/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) Uptown Greenville 9.4/10 Exceptional (105 reviews) "Friendly staff and rooms were clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy £117 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (with Sofabed) | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/84eda7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Jetted Tub (Oversized Room;with Sofabed) | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/954e0edb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/40fca348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Jetted Tub (Oversized Room;with Sofabed) | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/1344ea6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Suites-Greenville [](https://www.expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Suites-Greenville.h296584.Hotel-Information) 2.4 mi from Uptown Greenville 9.0/10 Wonderful (1,002 reviews) "I missed breakfast but i have stayed here before and it was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy £92 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Suites-Greenville.h296584.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/504a2b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/7b52f8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/5f6c9580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/f36e4e0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn and Suites by Marriott Washington [](https://www.expedia.co.uk/Greenville-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Washington.h18068553.Hotel-Information) 17.1 mi from Uptown Greenville 9.4/10 Exceptional (632 reviews) "Great staff, room was perfect!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa G £94 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Washington.h18068553.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/dc0a972b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/ea4d109f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/1c40a9e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/9c141e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Washington [](https://www.expedia.co.uk/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information) 17.4 mi from Uptown Greenville 8.2/10 Very good (673 reviews) "The room was very clean,the staff was great,and a very nice quiet night.best ive stayed in for a long time.would recommend it 100 percent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colin £84 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/a65a8dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/16e45970.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/405bc154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 Queen Bed, Accessible, Non Smoking (Mobility) | In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/0cb75355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Greenville/University Medic [](https://www.expedia.co.uk/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-GreenvilleUniversity-Medic.h2009531.Hotel-Information) 1.6 mi from Uptown Greenville 7.2/10 Good (1,004 reviews) "Staff is nice and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tonya £57 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-GreenvilleUniversity-Medic.h2009531.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/5ca75dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/07e25140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/7121fc84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/92dee2af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Greenville Near East Carolina University [](https://www.expedia.co.uk/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information) 3 mi from Uptown Greenville 8.6/10 Excellent (412 reviews) "Clean big room, great staff, clean from area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasmine £97 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/10000/4800/4797/9ebcae39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/4800/4797/aa11a8d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/10000/4800/4797/1d2f7390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/4800/4797/b575667a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Washington NC [](https://www.expedia.co.uk/Greenville-Hotels-Quality-Inn-Washington.h4797.Hotel-Information) 17.7 mi from Uptown Greenville 7.6/10 Good (350 reviews) "Staff was excellent. Room was absolutely perfect. breakfast was very good. The only problem I had was they charged me more than I was quoted from Expedia. I was a little shocked by the upcharge." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah £54 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Quality-Inn-Washington.h4797.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/9a769a39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/1ffe3d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/055764d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/ce0cefde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Greenville Medical Center by IHG [](https://www.expedia.co.uk/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) 1.4 mi from Uptown Greenville 9.4/10 Exceptional (267 reviews) "I enjoyed my stay very clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LATONYA £94 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) ![Apartment 1 - Pet Friendly | Private kitchen | Mini-fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/92000000/91200000/91195700/91195670/26b8cb2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment 1 - Pet Friendly | Premium bedding, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/92000000/91200000/91195700/91195670/53854a05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91200000/91195700/91195670/af1c9783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91200000/91195700/91195670/fa60b9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Inn on Main [](https://www.expedia.co.uk/Washington-Hotels-Little-Inn-At-Washington.h91195670.Hotel-Information) 18.4 mi from Uptown Greenville 9.6/10 Exceptional (77 reviews) "Great location, cute place, clean and comfy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany [](https://www.expedia.co.uk/Washington-Hotels-Little-Inn-At-Washington.h91195670.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/a07b88e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/6d7fbebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/7d1b886f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville by IHG [](https://www.expedia.co.uk/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) Convention District, 2.7 mi from Uptown Greenville 8.8/10 Excellent (1,000 reviews) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mustafa £95 includes taxes & fees 30 Jan - 31 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/90561384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/9d6fbb0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/36cd8e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/c64ceef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites By Hilton Greenville, NC [](https://www.expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) 1.5 mi from Uptown Greenville 9.4/10 Exceptional (324 reviews) "The staff was friendly and courteous. The rooms were clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robbins £103 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/30d4a3d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/e3500d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/00222959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/faaccec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Greenville by IHG [](https://www.expedia.co.uk/Greenville-Hotels-Holiday-Inn-Express-Greenville.h102482.Hotel-Information) 1.5 mi from Uptown Greenville 8.4/10 Very good (978 reviews) "Excellent hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca £94 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Holiday-Inn-Express-Greenville.h102482.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/9a1f8379.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/c12cd9d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/d914847d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/e731fa2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Greenville [](https://www.expedia.co.uk/Greenville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville.h20392562.Hotel-Information) 1.5 mi from Uptown Greenville 8.6/10 Excellent (461 reviews) "Great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keith £100 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville.h20392562.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/709881a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Pillow-top beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/f46e0d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/c6374af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 Queen Bed | Pillow-top beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/913bc50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Greenville NC by IHG [](https://www.expedia.co.uk/Greenville-Hotels-Candlewood-Suites-Greenville-NC.h1916890.Hotel-Information) 2.9 mi from Uptown Greenville 8.6/10 Excellent (597 reviews) "Excellent service, clean rooms, love the location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candida £73 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Candlewood-Suites-Greenville-NC.h1916890.Hotel-Information) ![Superior Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/42700/42698/893ee2da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42700/42698/b3192c7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/42700/42698/27cddd33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42700/42698/1eeb0df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Washington, NC [](https://www.expedia.co.uk/Greenville-Hotels-Magnuson-Hotel-Washington.h42698.Hotel-Information) 18.1 mi from Uptown Greenville 6.4/10 (99 reviews) "Nice and clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juanita £61 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Magnuson-Hotel-Washington.h42698.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/56c242c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/d5915891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/c899b353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/6151ea55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greenville [](https://www.expedia.co.uk/Greenville-Hotels-Hampton-Inn-Greenville.h2593867.Hotel-Information) Convention District, 2.6 mi from Uptown Greenville 9.0/10 Wonderful (586 reviews) "Great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario £105 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Hampton-Inn-Greenville.h2593867.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/21195757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Individually decorated, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/0a14a6d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/e84053b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/dbd945d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Greenville near University [](https://www.expedia.co.uk/Greenville-Hotels-Quality-Inn-Greenville-Near-University.h13542.Hotel-Information) 1.3 mi from Uptown Greenville 7.4/10 Good (1,002 reviews) "Love the stay there peaceful and good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ishwann £64 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Quality-Inn-Greenville-Near-University.h13542.Hotel-Information) ![Suite | Premium bedding, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/d374b4d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/b99bfdac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/551230eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/b467b520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Greenville [](https://www.expedia.co.uk/Greenville-Hotels-Baymont-By-Wyndham-Greenville.h10685.Hotel-Information) 3.4 mi from Uptown Greenville 6.4/10 (1,002 reviews) "Daily breakfast is great. Staff checking in was super nice. Room very spacious and clean comfortable bed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Norman £48 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Baymont-By-Wyndham-Greenville.h10685.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/e05fe4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/d316ab0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/e37e6770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/99dff1f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Marriott Greenville [](https://www.expedia.co.uk/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) Medical District, 1.7 mi from Uptown Greenville 8.8/10 Excellent (883 reviews) "Room was clean, service was quick!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen £100 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Jetted Tub | Down duvets, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/d55c4c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/82313f86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/74837550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/08b0695e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Greenville, NC [](https://www.expedia.co.uk/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) 4.2 mi from Uptown Greenville 7.6/10 Good (827 reviews) "Very clean room, and amazing kind attentive staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia £79 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=908648619872518144&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Uptown Greenville Find the best Uptown Greenville areas for the activities you enjoy most. - University District - Medical District - Convention District - College View Historic District - The Grid [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=988738433845506048) ![University District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:q%7EixEpwfwMaBkFm%5DkFtCgSkIpA%3Fi%5CkAyYtBwMhA%7B%5Dr%5D%7DbAb%5BjJmAla%40pHhI%5Cz%5DzJw%40%7DGbw%40yHvw%40iBe%40aA%7DAoK%7DB_CtIoAj%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=7ZMdeEUNFJC_bhtSRjJGhG6Yn58=) ### University District While University District isn't home to many top sights, Town Common and Dowdy–Ficklen Stadium are some notable places to visit nearby. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=988738433845506048) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=908649044914896896) ![Medical District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:m%7DhxEjpnwMg%5BmHa%40bEqG_Ab%40mEi%40GuFP%7BFnBkEh%40mBa%40sAcA%7DD%7BGdHcSnFq%5DD%7Dp%40h_%40%60MrJdXl%40%60ItHg%40xB%7CGzBvUo%40xJhBrEvGtJuHlGoG%5E&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=CqxUUl7Kw7wh3RKAYl1Goe92Yh0=) ### Medical District If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and South Greenville Park. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=908649044914896896) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=988732362615603200) ![Convention District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DtcxE%7E%7DjwMb%40qJ%7BHFSwKpAy_%40c%5C_C%60BiV%60bAbLBdo%40YpQgF%3FObCuNEaIJ&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=-ettVbAkgNluGu_90gCMwBxcKTY=) ### Convention District When in Convention District, you can plan a visit to 11 Galleria and Clark-LeClair Stadium, some noteworthy sights in the nearby area. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=988732362615603200) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=944331318232260608) ![College View Historic District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7BbjxEzcfwMyEmCbAaDeKqFPu%40lHnClDwJyC%7DAmA%7CC%7D%40q%40%7CB%7BIgF%7BCXcAbDpAt%40mD%3FgA%5CeAXsAbFtAToBjGlB_%40pA%60FdDuP%7Ei%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=0BESo8X4PcRQsIcIShCSIIeOH3k=) ### College View Historic District If you're looking for some top things to see and do in College View Historic District and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=944331318232260608) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=988738663997489152) ![The Grid map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:c%7DixEl%60ewMye%40qN%7BAiNjA%7DGvn%40dSmGrR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=j4wMA0q34XrOMWTJB0uVAfAkFqc=) ### The Grid While The Grid may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Town Common and Williams Arena at Minges Coliseum. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=988738663997489152) ## Top Uptown Greenville Hotel Reviews ![Fairfield Inn and Suites by Marriott Washington](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/5f6c9580_y.jpg) ### Fairfield Inn and Suites by Marriott Washington 10/10 Excellent "Room was very clean and well kept. The breakfast was good." [](https://expedia.co.uk/Greenville-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Washington.h18068553.Hotel-Information) ![Homewood Suites By Hilton Greenville, NC](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/36cd8e9e_y.jpg) ### Homewood Suites By Hilton Greenville, NC 10/10 Excellent "Rooms were exceptionally clean with lots of amenities. " [](https://expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) ![Best Western Plus Suites-Greenville](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/d19b7bd8_y.jpg) ### Best Western Plus Suites-Greenville 10/10 Excellent "I would definitely stay at this hotel again. The staff was professional and friendly, there was a good variety of food at breakfast and the room was clean and spacious." [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Suites-Greenville.h296584.Hotel-Information) ![ Comfort Inn & Suites Greenville near East Carolina University](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/5ca75dae_y.jpg) ### Comfort Inn & Suites Greenville near East Carolina University 10/10 Excellent "It was a great stay! " [](https://expedia.co.uk/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information) ![Hilton Garden INN Greenville University](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37_y.jpg) ### Hilton Garden INN Greenville University 10/10 Excellent "Every thing about the hotel is excellent including the breakfast " [](https://expedia.co.uk/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) ![Fairfield Inn & Suites by Marriott Greenville](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/03136946_y.jpg) ### Fairfield Inn & Suites by Marriott Greenville 10/10 Excellent "Great!" [](https://expedia.co.uk/Greenville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville.h20392562.Hotel-Information) ![Hampton Inn Washington](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/e3b75742_y.jpg) ### Hampton Inn Washington 10/10 Excellent "We stayed at the Hampton while visiting family for the weekend. My husband and I used to stay here years ago and we decided to stay here because they are pet friendly. I have to say it was a wonderful experience. We were greeted by the hotel staff with smiles and a helpful demeanor. Not just the reservation staff but ALL the staff. I don’t think I have ever been to a hotel where the staff was as friendly as here. The hotel has undergone some upgrades and felt clean even in the hallways. Our room was comfortable, clean and quiet. We were offered fresh coffee when we arrived and for breakfast. I would most certainly recommend this hotel. We will return for another stay the next time we are in Washington. " [](https://expedia.co.uk/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information) ![Staybridge Suites Greenville Medical Center by IHG](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/356f6fc4_y.jpg) ### Staybridge Suites Greenville Medical Center by IHG 10/10 Excellent "When we got there the room wasn't ready, and the lady was still cleaning, BUT, she and the front desk staff was so nice, I can't even complain. The room was spotless and so big... Only negative was that the hot water was not hot enough...I will be back soon! " [](https://expedia.co.uk/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) ## Frequently asked questions ### What is Uptown Greenville like? ### What's a favourite place to stay in Uptown Greenville? ### If I need to cancel my hotel reservation in Uptown Greenville, will I receive a refund? ### What is there to do around this Greenville neighbourhood? ## Explore a world of travel with Expedia - More ways to book - [Book Hotels in Uptown Greenville on Expedia.com ](https://www.expedia.com/Uptown-Greenville-Greenville-Hotels.0-n908648619872518144-0.Travel-Guide-Filter-Hotels)