Title: Uptown Greenville Travel Guide: Best of Uptown Greenville, Greenville Travel 2026 | Expedia.co.uk [Hotels in Uptown Greenville](https://expedia.co.uk/Uptown-Greenville-Hotels.d908648619872518144.Travel-Guide-Hotels)[Flights to Greenville](https://expedia.co.uk/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Uptown Greenville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Uptown-Greenville.d908648619872518144.Car-Hire-Guide)[Uptown Greenville Holidays](https://expedia.co.uk/Uptown-Greenville.d908648619872518144.Holidays-City-Breaks) # Uptown Greenville Travel Guide ## Greenville ![Aerial of Downtown Greenville SC South Carolina Skyline](https://images.trvl-media.com/place/908648619872518144/d19e8f2a-6aaf-40a2-a741-559f078407f5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Uptown Greenville Things to do Hotels Where to stay [Greenville travel guide](https://expedia.co.uk/Greenville.dx2779) --- ### Popular places to visit ![Park and Cupola (gazebo) on west end of campus of East Carolina University](https://images.trvl-media.com/place/6221225/835035ad-c4e4-44d6-ba53-31622dc2a4ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### East Carolina University Take a campus tour or just explore the area of East Carolina University during your travels in Greenville. Attend a sporting event in this family-friendly area. [](https://expedia.co.uk/East-Carolina-University-Greenville.d6221225.Attraction) #### Town Common Learn about the local history of Greenville when you spend time at Town Common. [](https://expedia.co.uk/Town-Common-Uptown-Greenville.d950929886174851072.Attraction) #### Greenville Museum of Art You can spend time exploring the galleries in Greenville Museum of Art in Greenville. [](https://expedia.co.uk/Greenville-Museum-Of-Art-Uptown-Greenville.d950930407864840192.Attraction) #### ECU Health Medical Center If ECU Health Medical Center is what brings you to town, hopefully you'll have a chance to explore more of Greenville. [](https://expedia.co.uk/Vidant-Medical-Center-Greenville.d6221234.Attraction) #### Greenville Convention Center Learn about the events happening in Greenville Convention Center during your trip to Greenville. [](https://expedia.co.uk/Greenville-Convention-Center-Greenville.d818566490237280256.Attraction) #### Greenville North Carolina Convention Center Learn about the events happening in Greenville North Carolina Convention Center during your trip to Greenville. [](https://expedia.co.uk/Greenville-North-Carolina-Convention-Center-Greenville.d811185100508377088.Attraction) --- ## Top hotels in Uptown Greenville ![Hilton Garden INN Greenville University](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden INN Greenville University 423 EVANS ST Greenville NC £113 3 May - 4 May includes taxes & fees Stay at this business-friendly hotel in Greenville. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Popular attractions Greenville Museum ... 9.4/10 Exceptional! (124 reviews) No pool, unfortunately. Newer hotel. Safe. Very clean. Kind staff. Great location. Reviewed on 27 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=03%2F05%2F2026&endDate=04%2F05%2F2026&selected=108395066&PinnedHotelID=108395066&HadPinnedHotel=true®ionId=908648619872518144) ![Microtel Inn & Suites by Wyndham Greenville/University Medic](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/a65a8dea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Microtel Inn & Suites by Wyndham Greenville/University Medic 450 Moye Blvd Greenville NC £59 12 Apr - 13 Apr includes taxes & fees Stay at this hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their reviews. ... 7/10 Good! (1,002 reviews) From the posted photos and exterior it looks great. Staff was friendly and welcoming, but when I got off the elevator on my floor, it completely smelled of cigarette smoke now all the doors have no smoking posted, but that still doesn’t stop them got into my first room and as soon as I open the door, ... Reviewed on 4 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F04%2F2026&endDate=13%2F04%2F2026&selected=2009531&PinnedHotelID=2009531&HadPinnedHotel=true®ionId=908648619872518144) ![Best Western Plus Suites-Greenville](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/84eda7b0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus Suites-Greenville 2310 Greenville Boulevard NE Greenville NC £104 14 Apr - 15 Apr includes taxes & fees Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ... 9/10 Wonderful! (1,004 reviews) Parking was easy. All areas of the hotel were clean. The staff was personable and courteous. Breakfast provided a good variety of both hot and cold items. Reviewed on 4 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=14%2F04%2F2026&endDate=15%2F04%2F2026&selected=296584&PinnedHotelID=296584&HadPinnedHotel=true®ionId=908648619872518144) ![Staybridge Suites Greenville Medical Center by IHG](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/9a769a39_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Staybridge Suites Greenville Medical Center by IHG 930 Crosswind Street Greenville NC £98 26 Apr - 27 Apr includes taxes & fees Stay at this hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Guy Smith Stadium and North Pines are located ... 9.4/10 Exceptional! (304 reviews) Great staff and hotel! Reviewed on 31 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=26%2F04%2F2026&endDate=27%2F04%2F2026&selected=104466390&PinnedHotelID=104466390&HadPinnedHotel=true®ionId=908648619872518144) ![Holiday Inn Express Greenville by IHG](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/30d4a3d9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express Greenville by IHG 909 Moye Blvd Greenville NC £109 19 Apr - 20 Apr includes taxes & fees Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the breakfast and the helpful staff ... 8.4/10 Very Good! (1,002 reviews) The room was clean but the toilet tank didn’t refill after flushing, the bathroom door was hard to unlock, the refrigerator wasn’t cold and the phone didn’t work. We were placed in another room which was fine. At breakfast they ran out of certain items by 8:15 and didn’t have anymore to refill it ... Reviewed on 5 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=102482&PinnedHotelID=102482&HadPinnedHotel=true®ionId=908648619872518144) ![Comfort Inn & Suites Greenville Near East Carolina University](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/5ca75dae_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn & Suites Greenville Near East Carolina University 3212 S Memorial Dr Greenville NC £101 19 Apr - 20 Apr includes taxes & fees Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ... 8.6/10 Excellent! (442 reviews) In general it was okay considering the rental price, however, i had some issues with the shower as it was not working, and had to just deal with it. Reviewed on 5 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=217352&PinnedHotelID=217352&HadPinnedHotel=true®ionId=908648619872518144) [See all 204 properties in Uptown Greenville](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=07%2F04%2F2026&endDate=08%2F04%2F2026®ionId=908648619872518144) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Uptown Greenville hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=2026-04-06&endDate=2026-04-07)[6 Apr - 7 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=2026-04-06&endDate=2026-04-07) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=2026-04-07&endDate=2026-04-08)[7 Apr - 8 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=2026-04-07&endDate=2026-04-08) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026)[10 Apr - 12 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=17%2F04%2F2026&endDate=19%2F04%2F2026)[17 Apr - 19 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=908648619872518144&startDate=17%2F04%2F2026&endDate=19%2F04%2F2026) --- ### Other neighbourhoods around Uptown Greenville ![durham north carolina](https://images.trvl-media.com/place/944331318232260608/4c34fdbc-0390-4fc3-95ea-8a2c57992e8f.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### College View Historic District If you're looking for some top things to see and do in College View Historic District and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium. [](https://expedia.co.uk/Greenville-College-View-Historic-District.dx944331318232260608) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Greenville Heights If you're looking for some top things to see and do in Greenville Heights and surrounding area, you can visit North Pines and Town Common. [](https://expedia.co.uk/Greenville-Greenville-Heights.dx553248635976482373) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Grid While The Grid may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Town Common and Williams Arena at Minges Coliseum. [](https://expedia.co.uk/Greenville-The-Grid.dx988738663997489152) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### University District While University District isn't home to many top sights, Town Common and Dowdy–Ficklen Stadium are some notable places to visit nearby. [](https://expedia.co.uk/Greenville-University-District.dx988738433845506048) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Medical District If you're looking for some top things to see and do in Medical District and surrounding area, you can visit North Pines and Arlington Crossing. [](https://expedia.co.uk/Greenville-Medical-District.dx908649044914896896) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Convention District When in Convention District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area. [](https://expedia.co.uk/Greenville-Convention-District.dx988732362615603200) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Uptown Greenville Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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