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Search Hotels Near Tybee Island Marine Science Center, Tybee Island

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Check prices for these dates

Tonight
9 Nov - 10 Nov
Tomorrow
10 Nov - 11 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Tybee Island Marine Science Center hotels

A two-story house with a balcony, a garage, and a driveway.

1. Desoto Beach Bed & Breakfast

Desoto Beach Bed & Breakfast
3.5 star property
South Beach, 0.9 mi from Tybee Island Marine Science Center
9.4 out of 10, Exceptional, (311 reviews)
"My friend and I stayed for 2 nights and had an absolutely lovely experience. Our host, Rick, was very kind, hospitable, and an excellent cook. Would definitely stay again!"
United States
Jayla
The price is £121
includes taxes & fees
8 Dec - 9 Dec
Desoto Beach Bed & Breakfast
A pool area with yellow lounge chairs and striped umbrellas, surrounded by a white fence and palm trees.

2. Royal Palms Motel

Royal Palms Motel
2.0 star property
South Beach, 1.4 mi from Tybee Island Marine Science Center
8.8 out of 10, Excellent, (349 reviews)
"We love staying at royal palms when in tybee always clean and easy check in"
United States
Margaret
The price is £57
includes taxes & fees
7 Dec - 8 Dec
Royal Palms Motel
A balcony with two wooden chairs and a small table, overlooking a beach.

3. Desoto Beach Terraces

Desoto Beach Terraces
3.0 star property
South Beach, 0.9 mi from Tybee Island Marine Science Center
8.4 out of 10, Very good, (126 reviews)
"The property is unique but has the best views. The inside is dated and they do not provide housekeeping during your stay- was not aware of that."
United States
Karolyn Hanson
The price is £135
includes taxes & fees
10 Dec - 11 Dec
Desoto Beach Terraces
A rooftop terrace with a rectangular pool, surrounded by seating areas and palm trees.

4. Dunes Inn & Suites

Dunes Inn & Suites
2.0 star property
Downtown Tybee Island, 2 mi from Tybee Island Marine Science Center
8.0 out of 10, Very good, (1,002 reviews)
"Would book again"
United States
Joshua
The price is £63
includes taxes & fees
18 Nov - 19 Nov
Dunes Inn & Suites
A beachfront hotel with multiple floors, a central glass facade, and a beach access walkway.

5. Hotel Tybee

Hotel Tybee
2.5 star property
Downtown Tybee Island, 2 mi from Tybee Island Marine Science Center
7.8 out of 10, Good, (1,270 reviews)
"view was beautiful super peaceful"
United States
Montane
The price is £115
includes taxes & fees
2 Dec - 3 Dec
Hotel Tybee
A bedroom with a bed, two bedside tables with lamps, a dresser, a window with curtains, and a painting on the wall.

6. Sea And Breeze Hotel And Condo

Sea And Breeze Hotel And Condo
2.5 star property
South Beach, 1.6 mi from Tybee Island Marine Science Center
7.8 out of 10, Good, (1,003 reviews)
"Great location!"
United States
Wendy
The price is £79
includes taxes & fees
10 Nov - 11 Nov
Sea And Breeze Hotel And Condo
A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

7. Sandcastle Inn

Sandcastle Inn
2.5 star property
Downtown Tybee Island, 1.9 mi from Tybee Island Marine Science Center
7.4 out of 10, Good, (1,003 reviews)
"Great place to stay"
United States
Kenneth
The price is £76
includes taxes & fees
10 Nov - 11 Nov
Sandcastle Inn
A balcony with a view of the beach, featuring lounge chairs, a small table, and umbrellas.

8. DeSoto Beach Hotel

DeSoto Beach Hotel
3.0 star property
South Beach, 0.9 mi from Tybee Island Marine Science Center
8.4 out of 10, Very good, (1,006 reviews)
"Our room was clean, I had an issue with the WiFi and maintenance was there within minutes. Loved my stay here"
United States
Ashley
The price is £99
includes taxes & fees
6 Dec - 7 Dec
DeSoto Beach Hotel
A narrow courtyard with a palm tree, a chair, and a small table.

9. DeSoto Beach Gardens

DeSoto Beach Gardens
2.5 star property
South Beach, 0.9 mi from Tybee Island Marine Science Center
8.4 out of 10, Very good, (246 reviews)
"The staff was very friendly! Breakfast was small but nice! The room was spacious but not clean. Mucky smell."
United States
Christine
The price is £105
includes taxes & fees
6 Dec - 7 Dec
DeSoto Beach Gardens
A hotel with a central courtyard featuring a fountain, outdoor seating, and palm trees.

10. The Inn & Club at Harbour Town

The Inn & Club at Harbour Town
5.0 star property
8.2 mi from Tybee Island Marine Science Center
9.6 out of 10, Exceptional, (253 reviews)
"Great stay"
United States
Lisa
The price is £298
includes taxes & fees
7 Dec - 8 Dec
The Inn & Club at Harbour Town
A pool area with lounge chairs and umbrellas, surrounded by palm trees.

11. Hilton Grand Vacations Club Ocean Oak Resort Hilton Head

Hilton Grand Vacations Club Ocean Oak Resort Hilton Head
4.0 star property
9.4 mi from Tybee Island Marine Science Center
9.6 out of 10, Exceptional, (387 reviews)
"Amazing"
United States
Sarah
The price is £194
includes taxes & fees
16 Nov - 17 Nov
Hilton Grand Vacations Club Ocean Oak Resort Hilton Head
A hotel room with a bed, a desk, a chair, a small table, a TV mounted on the wall, and a window with curtains.

12. Palmera Inn and Suites

Palmera Inn and Suites
3.0 star property
11.4 mi from Tybee Island Marine Science Center
9.0 out of 10, Wonderful, (1,535 reviews)
"The room was very spacious, bed was comfy— breakfast was very well maintained and great choices"
United States
Gail
The price is £76
includes taxes & fees
1 Dec - 2 Dec
Palmera Inn and Suites
A spacious living area with a high ceiling, large windows, and a central seating arrangement.

13. Marriott's Heritage Club

Marriott's Heritage Club
3.5 star property
8.2 mi from Tybee Island Marine Science Center
9.4 out of 10, Exceptional, (71 reviews)
"Great Villa! Very roomy and excellent location close to everything!"
United States
Christine
The price is £119
includes taxes & fees
2 Dec - 3 Dec
Marriott's Heritage Club
A Courtyard by Marriott hotel with a brick facade, multiple balconies, and a covered entrance area.

14. Courtyard by Marriott Hilton Head Island

Courtyard by Marriott Hilton Head Island
3.0 star property
10 mi from Tybee Island Marine Science Center
9.0 out of 10, Wonderful, (843 reviews)
"Great Place to stay. Excellent staff and property. Extra clean One drawback. The room refrigerator is too small."
United States
Daniel
The price is £104
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott Hilton Head Island
An aerial view of a resort with multiple buildings, a central swimming pool, and a beach in the background.

15. Marriott's Grande Ocean

Marriott's Grande Ocean
3.5 star property
9.3 mi from Tybee Island Marine Science Center
9.4 out of 10, Exceptional, (180 reviews)
"The property and room was very good. Marriott Service polite and friendly."
United States
Robert Alan
The price is £178
includes taxes & fees
30 Nov - 1 Dec
Marriott's Grande Ocean
A covered outdoor patio with seating, a fire pit, and a brick wall.

16. Home2 Suites by Hilton Hilton Head

Home2 Suites by Hilton Hilton Head
3.0 star property
12.4 mi from Tybee Island Marine Science Center
9.0 out of 10, Wonderful, (774 reviews)
"Great visit"
United States
Cheryl
The price is £91
includes taxes & fees
23 Nov - 24 Nov
Home2 Suites by Hilton Hilton Head
A resort with multiple swimming pools, sun loungers, and a view of the ocean.

17. Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort
4.0 star property
12 mi from Tybee Island Marine Science Center
9.0 out of 10, Wonderful, (1,003 reviews)
"Wonderful staff, great breakfast, clean room, and beach access!!"
United States
Miriam
The price is £200
includes taxes & fees
29 Nov - 30 Nov
Omni Hilton Head Oceanfront Resort
An outdoor seating area with a brick fire pit, a sofa, and a table.

18. SpringHill Suites by Marriott Hilton Head Island

SpringHill Suites by Marriott Hilton Head Island
2.5 star property
12.4 mi from Tybee Island Marine Science Center
8.8 out of 10, Excellent, (647 reviews)
"Breakfast"
United States
Keith
The price is £81
includes taxes & fees
15 Nov - 16 Nov
SpringHill Suites by Marriott Hilton Head Island
A resort with a large pool, palm trees, and a view of the ocean.

19. Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island
4.0 star property
11.2 mi from Tybee Island Marine Science Center
8.8 out of 10, Excellent, (1,573 reviews)
"Courteous and helpful staff made our stay pleasant and enjoyable."
United States
Everette
The price is £160
includes taxes & fees
29 Nov - 30 Nov
Sonesta Resort Hilton Head Island
A resort pool with clear water, surrounded by lounge chairs and umbrellas, with a beach and ocean view in the background.

20. Beach House Resort Hilton Head

Beach House Resort Hilton Head
4.0 star property
9.8 mi from Tybee Island Marine Science Center
8.6 out of 10, Excellent, (1,595 reviews)
"Right on the beach, resort feel. Great pool and food"
United States
Charlotte
The price is £147
includes taxes & fees
20 Nov - 21 Nov
Beach House Resort Hilton Head
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Tybee Island Marine Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A two-story house with a balcony, a garage, and a driveway.
Desoto Beach Bed & Breakfast
3.5 star property
9.4
Exceptional
311 reviews
View
A pool area with yellow lounge chairs and striped umbrellas, surrounded by a white fence and palm trees.
Royal Palms Motel
2.0 star property
8.8
Excellent
349 reviews
View
A balcony with two wooden chairs and a small table, overlooking a beach.
Desoto Beach Terraces
3.0 star property
8.4
Very good
126 reviews
View
A rooftop terrace with a rectangular pool, surrounded by seating areas and palm trees.
Dunes Inn & Suites
2.0 star property
8.0
Very good
1,002 reviews
View
A beachfront hotel with multiple floors, a central glass facade, and a beach access walkway.
Hotel Tybee
2.5 star property
7.8
Good
1,270 reviews
View

Other attractions near Tybee Island Marine Science Center

An old, weathered building with a sign reading "Battery Brauery 1899".

Battery Brumby

8.0/10 (5 reviews)
You can learn about the history of Tybee Island with a trip to Battery Brumby. Wander through the beautiful beaches and seaside in this family-friendly area.
See properties

Top Tybee Island Marine Science Center Hotel Reviews

A hotel with a central courtyard featuring a fountain, outdoor seating, and palm trees.
The Inn & Club at Harbour Town

The Inn & Club at Harbour Town

The Inn & Club at Harbour Town
Sea Pines

10/10 Excellent

Beautiful hotel with emphasis on quality and service. Ideal location convenient to harbour and beach. Immaculate throughout.
United Kingdom
Alwyn
Reviewed June 2, 2026
The Inn & Club at Harbour Town

Frequently Asked Questions

What's the area like around Tybee Island Marine Science Center?

Tybee Island Marine Science Center is located in a walkable area of Tybee Island known for its beautiful beaches and dolphin watching opportunities. If you're looking for a convenient place to stay, take a look at the 602 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Tybee Island Marine Science Center?

DeSoto Beach Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.9 mi (1.4 km) from Tybee Island Marine Science Center. Another good choice is Lighthouse Point 1 by Tybee Vacation Rentals, located just 0.4 mi (0.7 km) away.

How many hotels will I find close to Tybee Island Marine Science Center?

Expedia has 602 hotels and other accommodation options within a mile from Tybee Island Marine Science Center.

If I need to cancel the hotel reservation for my stay near Tybee Island Marine Science Center, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer near Tybee Island Marine Science Center.

What can I see and do near Tybee Island Marine Science Center?

You'll want to browse the exhibits at Tybee Island Light Station and Museum and Battery Garland. Fort Screven, Fort Pulaski National Monument and Battery Brumby are some of the local landmarks to explore. You might spend a leisurely day outdoors at Tybee Island Memorial Park and Jaycee Park.