Luxury Hotels in Southwest Oklahoma
United States of America
Luxury Hotels
Expedia.co.uk

Southwest Oklahoma Travel Guide Hotels in Southwest Oklahoma Flights to Southwest Oklahoma Car Hire in Southwest Oklahoma Southwest Oklahoma Holiday Packages Holiday Rentals in Southwest Oklahoma

A coastal resort with buildings, a lake, and red rock formations.

Find luxury hotels in Southwest Oklahoma, OK

Where to?

Dates

Travellers

Room 1

Adults

ChildrenAges 0 to 17

Need to book 9 or more rooms?

Change your mind
Book hotels with free cancellation
Treat yourself
Save instantly and earn perks with One Key
Learn about One Key
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Southwest Oklahoma luxury hotels

Wicker chairs with black cushions, a glass table, and a vase with flowers.

A modern restaurant with a wooden table and black chairs, a stone accent wall, and a fireplace.

A modern hotel room with two beds, a dark headboard, bedside lamps, and a large window.

A parking lot with a building labeled "IRISH INN" and a sign with American flag and five stars.

1. The Irish Inn Boutique Hotel

The Irish Inn Boutique Hotel

4.0 star property

Shamrock

9.8 out of 10, Exceptional, (65 reviews)

9.8/10

Exceptional

(65 reviews)

The price is £127

£127

includes taxes & fees

14 Nov - 15 Nov

The Irish Inn Boutique Hotel

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Top Southwest Oklahoma Hotel Reviews

An outdoor patio with stone walls, wicker furniture, and a built-in fire feature.

A hotel lobby with a reception desk, seating area, and a fireplace.

A multi-story hotel with a modern design, featuring a prominent entrance and a clear sky.

A modern bar area with a counter, seating, and a stone wall.

Residence Inn by Marriott Wichita Falls

Wichita Falls

10/10 Excellent

Clean room and great service

Paul

Reviewed March 16, 2026Reviewed March 16, 2026

Residence Inn by Marriott Wichita Falls

A building entrance with a covered walkway, columns, and a stone facade.

A hotel lobby with a reception desk, a waiting area with a sofa, and a large glass door leading outside.

A hotel room with two beds, a kitchenette, a flat-screen TV, and a large window.

A hotel reception desk with a modern design, a digital display, and a glass door entrance.

Holiday Inn Express Hotel & Suites Vernon College Area by IHG

Vernon

10/10 Excellent

Renee and Penny make this hotel for us .Been before and would go again.

William

Reviewed June 27, 2017Reviewed June 27, 2017

Holiday Inn Express Hotel & Suites Vernon College Area by IHG

A modern hotel entrance with a prominent sign reading "LA QUINTA".

A modern hotel kitchen with a long counter, food dispensers, and a coffee station.

A bar area with a long counter, multiple bar stools, and hanging crystal chandeliers.

A reception area with a blue ceiling, a wall with wind turbines and the text "rise up on the bright side," and a refrigerator stocked with beverages.

La Quinta Inn & Suites by Wyndham Clinton Historic Route 66

Clinton

10/10 Excellent

Can’t fault this hotel! We had a fantastic night’s sleep and woke up to the most beautiful sunrise. The perfect way to start the day. Would definitely stay here again!

Peta

Reviewed August 11, 2026Reviewed August 11, 2026

La Quinta Inn & Suites by Wyndham Clinton Historic Route 66

An indoor swimming pool with multiple water features, including a central fountain and water jets.

A spacious indoor area with large windows, a central red arch structure, and a tiled floor.

A Holiday Inn Express hotel with a central entrance, multiple floors, and a parking lot.

A buffet counter with labeled containers of turkey sausage and cookies.

Holiday Inn Express Hotel & Suites Elk City by IHG

Elk City

8/10 Good

Expected standard from this chain, everything we wanted

Martin

Reviewed September 9, 2023Reviewed September 9, 2023

Holiday Inn Express Hotel & Suites Elk City by IHG

A La Quinta Inn & Suites building with a flat roof, multiple windows, and a parking lot.

A hotel room with a kitchenette, a desk, a television, and a sofa.

A modern kitchen with grey cabinets, a tiled backsplash, and a long countertop with various appliances and food items.

A hotel lobby with a reception desk, purple chairs, a blue sofa, and a patterned rug.

La Quinta Inn & Suites by Wyndham Weatherford OK

Weatherford

8/10 Good

Would have liked to have been within walking distance to restaurants after a long day’s drive. Didn’t really want to get back in the car again. The hotel was very nice though and the staff helpful and friendly

Peni

Reviewed September 19, 2025Reviewed September 19, 2025

La Quinta Inn & Suites by Wyndham Weatherford OK

A modern living room with leather sofas, armchairs, and a TV mounted on a brick wall.

A buffet area with various food options, including bread, fruits, and a coffee machine.

A hotel with a red-tiled roof, a covered parking area, and a sign indicating it is a hotel.

A hotel room with a large bed, bedside tables, a lamp, a framed picture on the wall, and a desk with a mirror.

Lucille's Hotel, Restaurant, & Bar

Weatherford

10/10 Excellent

Great facility and very helpful staff.

Peter

Reviewed October 9, 2026Reviewed October 9, 2026

Lucille's Hotel, Restaurant, & Bar

A modern hotel with a prominent 'MYSUITES' sign, featuring a clean, contemporary design with multiple units and a well-maintained exterior.

A modern kitchen with wooden cabinets, a microwave, toaster, and a refrigerator.

A hotel room with a sofa, a small wooden table, a desk with chairs, a flat-screen TV, a ceiling fan, and a bed with a window.

An outdoor patio area with a round table and chairs, string lights, and a white fence.

MySuites Lawton

Lawton

10/10 Excellent

Stayed one night as travelling through the area, very helpful front desk staff who went above and beyond expectations. Very spacious room and comfortable beds, lovely powerful shower, highly recommended

Vanessa

Reviewed April 10, 2024Reviewed April 10, 2024

MySuites Lawton

A modern hotel with a covered entrance, multiple windows, and a flagpole with the American flag.

A modern hotel lobby with a central bar area, seating arrangements, and decorative elements.

An indoor swimming pool with clear water, surrounded by a tiled floor and walls, with windows on one side and a seating area with chairs on the other.

A hotel reception area with a reception desk, a large framed picture on the wall, a refrigerator, and a patterned rug on the floor.

Hampton Inn El Reno

El Reno

10/10 Excellent

Really nice hotel and quiet place ( plush)

Dominic R

Reviewed March 8, 2024Reviewed March 8, 2024

Hampton Inn El Reno

Explore a world of travel with Expedia

Lodging
Flights
Packages
Cars
Holiday Rentals

Gay-Friendly Hotels in Altus
Standard Link for Gay-Friendly Hotels in Altus
Buffalo Wallow Cabin at The Lazy Buffalo Hunting Pet Friendly Wichita Mountains
Standard Link for Buffalo Wallow Cabin at The Lazy Buffalo Hunting Pet Friendly Wichita Mountains
Hey
Standard Link for Hey
Cache Hotels
Standard Link for Cache Hotels
Calumet Hotels
Standard Link for Calumet Hotels
Family friendly Countryside stay! Easy access to Route 66 and I
Standard Link for Family friendly Countryside stay! Easy access to Route 66 and I
Comanche Hotels
Standard Link for Comanche Hotels
Cooperton Hotels
Standard Link for Cooperton Hotels
Dill City Hotels
Standard Link for Dill City Hotels
Holiday Inn Express & Suites Duncan by IHG
Standard Link for Holiday Inn Express & Suites Duncan by IHG
Charming country home with WiFi
Standard Link for Charming country home with WiFi
Bedford Inn
Standard Link for Bedford Inn
Bluebird Place Rachel Room
Standard Link for Bluebird Place Rachel Room
Executive Plus Inn & Suites
Standard Link for Executive Plus Inn & Suites
Holiday Inn Express & Suites Clinton by IHG
Standard Link for Holiday Inn Express & Suites Clinton by IHG
Oyo Hotel Elk City OK Route 66
Standard Link for Oyo Hotel Elk City OK Route 66
La Quinta Inn & Suites by Wyndham Elk City
Standard Link for La Quinta Inn & Suites by Wyndham Elk City
Super 8 by Wyndham Elk City
Standard Link for Super 8 by Wyndham Elk City
Trade Winds Inn Clinton
Standard Link for Trade Winds Inn Clinton
1 mile to Fort Sill! The CaroleBelle Cottage sleeps 8 with hottub/grills/firepit
Standard Link for 1 mile to Fort Sill! The CaroleBelle Cottage sleeps 8 with hottub/grills/firepit
Capital O Travelers Inn Lawton Fort Sill
Standard Link for Capital O Travelers Inn Lawton Fort Sill
Lawton/Fort Sill Home near Airport
Standard Link for Lawton/Fort Sill Home near Airport
Little Cabin at the DonkeyRanch
Standard Link for Little Cabin at the DonkeyRanch
Newly renovated cozy cottage
Standard Link for Newly renovated cozy cottage
Stylish cabin near Medicine Park
Standard Link for Stylish cabin near Medicine Park
Lawton Hotels
Standard Link for Lawton Hotels
Marlow Hotels
Standard Link for Marlow Hotels
Easy Rider Cabin
Standard Link for Easy Rider Cabin
Senator Elmer Thomas Historic Home on Medicine Creek in Medicine Park
Standard Link for Senator Elmer Thomas Historic Home on Medicine Creek in Medicine Park
In the Heart of Medicine Park
Standard Link for In the Heart of Medicine Park
Surf Shack at Triple Z
Standard Link for Surf Shack at Triple Z
Meers Hotels
Standard Link for Meers Hotels
Sentinel Hotels
Standard Link for Sentinel Hotels
Best Western Plus Weatherford
Standard Link for Best Western Plus Weatherford
Hotels near Wichita Mountains Wildlife Refuge
Standard Link for Hotels near Wichita Mountains Wildlife Refuge
Hotels near Winter Creek Golf Club
Standard Link for Hotels near Winter Creek Golf Club

Flights to Amber
Standard Link for Flights to Amber
Flights to Cache
Standard Link for Flights to Cache
Flights to Clinton
Standard Link for Flights to Clinton
Flights to Fort Sill
Standard Link for Flights to Fort Sill
Flights to Hydro
Standard Link for Flights to Hydro
Flights to Lawton
Standard Link for Flights to Lawton
Flights to Marlow
Standard Link for Flights to Marlow
Flights to Sentinel
Standard Link for Flights to Sentinel
Flights to Verden
Standard Link for Flights to Verden
Flights from Mangum
Standard Link for Flights from Mangum
Flights from Birmingham (BHM) to Lawton (LAW)
Standard Link for Flights from Birmingham (BHM) to Lawton (LAW)
Flights from New York (JFK) to Clinton (CLK)
Standard Link for Flights from New York (JFK) to Clinton (CLK)
Flights from Kankan (KNN) to Duncan (DUC)
Standard Link for Flights from Kankan (KNN) to Duncan (DUC)
Flights from London (LHR) to Lawton (LAW)
Standard Link for Flights from London (LHR) to Lawton (LAW)

Cache Holidays
Standard Link for Cache Holidays
Comanche Holidays
Standard Link for Comanche Holidays
Visit Devol
Standard Link for Visit Devol
Visit Geronimo
Standard Link for Visit Geronimo
Hydro Holidays
Standard Link for Hydro Holidays
Visit Lawton
Standard Link for Visit Lawton
Lone Wolf Holidays
Standard Link for Lone Wolf Holidays
Waterpark Holiday Packages Southwest Oklahoma
Standard Link for Waterpark Holiday Packages Southwest Oklahoma
Sentinel Holidays
Standard Link for Sentinel Holidays
Visit Southwest Oklahoma
Standard Link for Visit Southwest Oklahoma
Walters Holidays
Standard Link for Walters Holidays
Water-Zoo Indoor Water Park
Standard Link for Water-Zoo Indoor Water Park

Firefly Cyprus Rental Cars in Duke
Standard Link for Firefly Cyprus Rental Cars in Duke

Custer County Holiday Rentals
Standard Link for Custer County Holiday Rentals
Lone Wolf Holiday Rentals
Standard Link for Lone Wolf Holiday Rentals

Find luxury hotels in Southwest Oklahoma, OK

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southwest Oklahoma luxury hotels

1. The Irish Inn Boutique Hotel

Top Southwest Oklahoma Hotel Reviews

Residence Inn by Marriott Wichita Falls

10/10 Excellent

Explore a world of travel with Expedia