Title: TOP Adults Only Resorts & Hotels in Southwest, MS for 2026 | Expedia.co.uk [Southwest Travel Guide](https://expedia.co.uk/Southwest.dx6058704)[Hotels in Southwest](https://expedia.co.uk/Southwest-Hotels.d6058704.Travel-Guide-Hotels)[Holiday Rentals in Southwest](https://expedia.co.uk/Southwest-Holiday-Rentals.d6058704.Travel-Guide-HolidayRentals)[Flights to Southwest](https://expedia.co.uk/Cheap-Flights-To-Southwest.d6058704.Travel-Guide-Flights)[Things to do in Southwest](https://expedia.co.uk/Things-To-Do-In-Southwest.d6058704.Travel-Guide-Activities)[Southwest Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest.d6058704.Car-Hire-Guide)[Southwest Holidays](https://expedia.co.uk/Southwest.d6058704.Holidays-City-Breaks) ![Not the most spectacular photo but a very spectacular building and story. This 150-year-old house was never completed. The exterior incredibly magnificent but step inside and the top four floors… Or still in the same condition as when the craftsman left in 1865. Well worth the stop!](https://images.trvl-media.com/place/7671/fef4ceb3-3748-46c9-b2f8-73d43339f6b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Quentin White ![](https://images.trvl-media.com/place/7671/fef4ceb3-3748-46c9-b2f8-73d43339f6b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Adults Only Resorts & Hotels Tonight [28 Jan - 29 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-01-28&endDate=2026-01-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [29 Jan - 30 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6058704&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Our top choices for Southwest adults-only hotels ![Premium bedding, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279011/d7393733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279011/a52c1035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279011/7a5dfd96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279011/b96f327d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WaterView Casino & Hotel, Trademark Collection by Wyndham [](https://www.expedia.co.uk/Vicksburg-Hotels-WaterView-Casino-And-Hotel.h13279011.Hotel-Information) Vicksburg 8.0/10 Very good (1,000 reviews) "I loved that hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia M. £64 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Vicksburg-Hotels-WaterView-Casino-And-Hotel.h13279011.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/20000000/19200000/19197500/19197423/365b3302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/20000000/19200000/19197500/19197423/b34cf8dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/20000000/19200000/19197500/19197423/abe727cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19200000/19197500/19197423/40840e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone House Musical B&B [](https://www.expedia.co.uk/Natchez-Hotels-Stone-House-Musical-BB.h19197423.Hotel-Information) Natchez 9.8/10 Exceptional (29 reviews) "We enjoyed the historical surroundings and the host was charming and gave us a wonderful tour of the B&B. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy £120 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Natchez-Hotels-Stone-House-Musical-BB.h19197423.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/24000000/23500000/23490500/23490498/6962a984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, Egyptian cotton sheets, premium bedding, memory-foam beds](https://images.trvl-media.com/lodging/24000000/23500000/23490500/23490498/3016c0df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/24000000/23500000/23490500/23490498/81aba14d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![48-inch Smart TV with digital channels, TV, books](https://images.trvl-media.com/lodging/24000000/23500000/23490500/23490498/dc8a290d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverboat Bed & Breakfast [](https://www.expedia.co.uk/Natchez-Hotels-Riverboat-Bed-Breakfast.h23490498.Hotel-Information) Natchez 9.8/10 Exceptional (17 reviews) "Awesome place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher £161 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Natchez-Hotels-Riverboat-Bed-Breakfast.h23490498.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-11&endDate=2026-02-12®ionId=6058704&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southwest ### Discover top Southwest attractions The Southwest region of the United States is a paradise of adventure and natural beauty that caters to those seeking memorable family experiences. Begin your journey at the majestic Grand Canyon, where you can hike the scenic trails or take a thrilling helicopter tour for breathtaking aerial views of this iconic landmark. Next, explore the enchanting landscapes of Sedona, famous for its stunning red rock formations and spiritual vortexes, perfect for families wanting to embrace nature through hiking, biking, or even jeep tours. For a taste of the Wild West, visit the historic town of Tombstone, where you can immerse yourselves in the rich history of gunfights and saloons, offering a thrilling yet educational experience for children and adults alike. Don't miss the otherworldly beauty of Monument Valley, where you can enjoy guided Navajo tours, learning about indigenous culture while surrounded by breathtaking vistas. When it comes to accommodation, consider staying in the vibrant city of Santa Fe, known for its adobe architecture and art scene. Here, you can enjoy luxurious hotels that provide exceptional service and an authentic Southwestern experience, with convenient access to local galleries and markets. With its unique blend of culture, history, and adventure, the Southwest invites families to create unforgettable memories. ## Top Southwest Hotel Reviews ## Frequently asked questions ### How much do adults-only hotels in Southwest cost? ### How can I find cheap adults-only hotels in Southwest? ### From what age can you stay in an adult-only hotel in Southwest? ### Are all adult-only resorts all-inclusive in Southwest? ### Why book your adults-only hotel in Southwest with Expedia? ### When is the best time to stay at an adult-only all-inclusive resort in Southwest? ### Can I cancel or change my adult-only resort booking? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [Bolton Hotels ](https://www.expedia.co.uk/Bolton-Hotels.d553248635975847266.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Brandon ](https://www.expedia.co.uk/Brandon-Hotels-Gay-Friendly-Hotel.0-0-d6754-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Brookhaven ](https://www.expedia.co.uk/Brookhaven-Hotels-Family-Friendly-Hotel.0-0-d7084-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - 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