Siesta Isle Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £335 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Siesta Isle Holiday

When it's time for your next escape, lock in a Siesta Isle holiday package. From its nature to a whole lot more, there are so many tempting reasons to pick this neighbourhood. When it's time to see the sights, you'll find lots of top attractions nearby including Fishing Pier Fort Myers Beach, Bunche Beach and Jungle Golf Ft. Myers. Visit one, two or all during your trip to Siesta Isle. Stop daydreaming and start doing. When you're ready to book your holiday to Siesta Isle, Expedia will help get you there.

Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most. Learn more about Siesta Isle
Sunset on the island of Sanibel.Florida.USA

Mid Island

1 out of top 10 points of interest in this area
4.5/5(2 area reviews)

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

Find hotels in Mid Island

Top hotels in Siesta Isle

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 out of 5
17990 San Carlos Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is £94 per night from 3 May to 4 May
£94
3 May - 4 May
includes taxes & fees
8.8/10 Excellent! (1,004 reviews)
Loved the garden and breakfast area! Definitely will stay here again!

Reviewed on 11 Apr 2026

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
The price is £87 per night from 19 Apr to 20 Apr
£87
19 Apr - 20 Apr
includes taxes & fees
9.2/10 Wonderful! (1,386 reviews)
Room was neat, clean and tidy. Staff was friendly, breakfast was good and filling. Able to park easily.

Reviewed on 11 Apr 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is £220 per night from 13 May to 14 May
£220
13 May - 14 May
includes taxes & fees
9/10 Wonderful! (2,006 reviews)
Awesome

Reviewed on 11 Apr 2026

Margaritaville Beach Resort Fort Myers
See all 17,721 properties in Siesta Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Siesta Isle travel package cost?
We make it easy to explore the world, with Siesta Isle travel packages starting from as low as . You'll have the flexibility to bundle your preferred hotels, airlines and car rental. For the ultimate getaway, why not add a couple of activities and tours to your itinerary?
If I'm not able to travel, can I cancel my Siesta Isle travel package?
Don't worry if you're rethinking your Siesta Isle travel package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We understand life can occasionally throw a spanner in the travel works, so head to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.
How do I get a cheap travel package to Siesta Isle?
Book everything in one place with our Siesta Isle travel packages. You'll discover bargains on flights, hotels, tours and more that'll keep your wallet happy and your adventurous side busy. And, with more than 550 partner airlines and 1,000,000 properties across the globe to select from, you have countless opportunities to mix and match your own way.
Does Expedia offer Book Now, Pay Later Siesta Isle holidays?
Your bank balance shouldn't stop you from escaping on holiday, so Expedia has worked out a solution to help. Thanks to our partnership with online lender Klarna, it's easier than ever to book your dream getaway without draining your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your trip. Check out these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month works for you, Klarna offers just that! Paying in convenient monthly instalments will make your holiday dreams come true.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your trip in multiple transactions.
  • Low deposit holidays: When you spot an amazing deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you lock in your getaway.

Where should I stay in Siesta Isle?
Close to the action. Many visitors book hotels in the vicinity of top sights, like Fishing Pier Fort Myers Beach, Jungle Golf Ft. Myers and Bunche Beach.
What are the top hotels in Siesta Isle?
Secure a room at Wyndham Garden Fort Myers Beach. It's one of the neighbourhood's most sought-after properties. Another top-rated option in Siesta Isle is Best Western Plus Beach Resort.
How far in advance should I book my Siesta Isle holiday?
Travellers are generally able to browse international flights on Expedia up to a year in advance of departure. Booking late? With a little bit of luck, it's still possible to score a cheaper ticket only weeks before your flight.
What does an Expedia Siesta Isle travel package include?
That depends entirely on you. You can choose from a variety of Siesta Isle bundles, such as a rental car, flight and hotel. You can also book a flight with a hotel, or a rental car and a flight. Once you've made your booking, you can add the fun stuff like experiences and activities. Whatever your dream Siesta Isle trip looks like, get ready to save!
What should I know before booking a Siesta Isle travel package?
So many places to wander around, so many things to see and do. With a package, you can check more of them off your list. Combine your flights, hotels and rental cars and land big savings.
Can I choose my airline with a Siesta Isle Expedia travel package?
You can, and with over 550 airlines to choose from worldwide, you have plenty of choice. Have a look through the available options and see which airline best suits your budget and needs.

Popular places to visit

Santini Marina Shopping Plaza

You can do some window-shopping at Santini Marina Shopping Plaza during your trip to Fort Myers Beach. Wander the beautiful beaches or discover the beautiful sunsets in this family-friendly area.

Santini Marina Shopping Plaza

Bay Oaks Recreation Center

After visiting Bay Oaks Recreation Center, make a plan to see the other sights and activities in Fort Myers Beach. Stroll along the beautiful beaches in this family-friendly area or visit its lively bars.

Bay Oaks Recreation Center

Things to do

Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

£52
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

£48
per adult
Dolphin Wildlife Cruise Fort Myers Beach
Copacetic Day Sail

Copacetic Day Sail

£52
per adult
100% of travellers recommend
Copacetic Day Sail
See all activities in Fort Myers Beach

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.