Search Hotels in Siesta Isle, Fort Myers Beach

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Apr - 13 Apr
Tomorrow
13 Apr - 14 Apr
Next weekend
17 Apr - 19 Apr
In two weeks
24 Apr - 26 Apr

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Siesta Isle hotels

Sun deck

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1,004 reviews)
"Lovely sunset views, fire pit table by the docks, hammocks"
United States
Debbie
The price is £94
includes taxes & fees
3 May - 4 May
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
3 restaurants, breakfast, lunch, dinner served; Italian cuisine

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
1.7 mi from Siesta Isle
9.0 out of 10, Wonderful, (1,374 reviews)
"This hotel exceeded my expectations literally right on the beach. Great food options and the staff was wonderful "
United States
Giovanna
The price is £141
includes taxes & fees
12 May - 13 May
Lani Kai Beachfront Resort
Lobby

MainStay Suites Fort Myers East I-75

MainStay Suites Fort Myers East I-75
2.5 star property
15.8 mi from Siesta Isle
9.6 out of 10, Exceptional, (340 reviews)
"Clean, quiet, good staff, well thought out rooms with plenty of storage."
United States
James
The price is £67
includes taxes & fees
12 May - 13 May
MainStay Suites Fort Myers East I-75
Lobby

Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
7.7 mi from Siesta Isle
8.8 out of 10, Excellent, (938 reviews)
"Easy parking breakfast is $15 a plate and clean rooms "
United States
Kayla
The price is £57
includes taxes & fees
19 Apr - 20 Apr
Extended Stay America Premier Suites - Fort Myers - Airport
Restaurant

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
1.6 mi from Siesta Isle
7.6 out of 10, Good, (382 reviews)
"So clean. Best view on the island. Staff was helpful. Check out the Bay Inn across the street. Sister hotel just as nice and a little more budget friendly. "
United States
Jan
The price is £122
includes taxes & fees
13 Apr - 14 Apr
The Bay Inn at Lani Kai
Interior

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
11.1 mi from Siesta Isle
9.6 out of 10, Exceptional, (1,024 reviews)
"Excellent stay, clean, friendly staff. Would stay again"
United States
Terri
The price is £87
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express & Suites Fort Myers Airport by IHG
View from room

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
South Island, 5.1 mi from Siesta Isle
9.2 out of 10, Wonderful, (1,007 reviews)
"Beautiful beach view, friendly staff and lots of beach space for our family to enjoy!"
United States
Daniel
The price is £383
includes taxes & fees
3 May - 4 May
Pointe Estero Beach Resort
Property amenity

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
9.9 mi from Siesta Isle
9.2 out of 10, Wonderful, (180 reviews)
"Great size room and the front desk staff was Great!"
United States
Karen
The price is £91
includes taxes & fees
10 May - 11 May
TownePlace Suites by Marriott Fort Myers Gulf Coast
Deluxe Single Room | Living area | 55-inch Smart TV with cable channels, streaming services

The Anchor Inn

The Anchor Inn
2.0 star property
6 mi from Siesta Isle
10.0 out of 10, Exceptional, (20 reviews)
"The property was beautiful, everything was in perfect condition, would definitely go back!!"
United States
Jennifer
The price is £207
includes taxes & fees
26 Apr - 27 Apr
The Anchor Inn
On the beach, sun-loungers, beach towels

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
6.3 mi from Siesta Isle
9.2 out of 10, Wonderful, (1,769 reviews)
"Hotel was clean and great access to walking, restaurants and stores"
United States
Lisa
The price is £219
includes taxes & fees
13 May - 14 May
Sanibel Island Beach Resort
2 outdoor pools, pool cabanas (surcharge), pool umbrellas

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
16.4 mi from Siesta Isle
9.4 out of 10, Exceptional, (744 reviews)
"Great property, will stay again. "
United States
Jamie
The price is £200
includes taxes & fees
3 May - 4 May
The Perry Hotel Naples
Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

Comfort Inn Fort Myers Northeast

Comfort Inn Fort Myers Northeast
2.5 star property
17.5 mi from Siesta Isle
7.8 out of 10, Good, (715 reviews)
"Friendly staff!"
United States
Tom
The price is £60
includes taxes & fees
19 Apr - 20 Apr
Comfort Inn Fort Myers Northeast
Lobby

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
15.9 mi from Siesta Isle
9.6 out of 10, Exceptional, (438 reviews)
"I had a wonderful stay, was surprised how clean and up to date it was"
United States
Chavanna
The price is £77
includes taxes & fees
10 May - 11 May
Comfort Suites Fort Myers East I-75
Exterior

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
1.1 mi from Siesta Isle
9.4 out of 10, Exceptional, (1,318 reviews)
"Incredible beach view, staff, and the facilities were extremely clean"
United States
Kelly
The price is £249
includes taxes & fees
26 Apr - 27 Apr
Pink Shell Beach Resort and Marina
Free daily buffet breakfast

Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75
3.5 star property
10.8 mi from Siesta Isle
9.0 out of 10, Wonderful, (1,005 reviews)
"The staff was very accommodating, made sure we got checked in early and helped us with everything we needed. "
United States
Matthew
The price is £88
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn Fort Myers-Airport & I-75
Lobby

Days Inn & Suites by Wyndham Bonita Springs North Naples

Days Inn & Suites by Wyndham Bonita Springs North Naples
2.5 star property
15.9 mi from Siesta Isle
7.8 out of 10, Good, (1,017 reviews)
"Great location."
United States
Franz
The price is £66
includes taxes & fees
19 Apr - 20 Apr
Days Inn & Suites by Wyndham Bonita Springs North Naples
Reception

Shangri-La Springs

Shangri-La Springs
2.5 star property
14.5 mi from Siesta Isle
9.2 out of 10, Wonderful, (207 reviews)
"Rooms were clean, Nicely redone. The grounds were beautiful and the service was fantastic! Will definitely stay again. "
United States
Matthew
The price is £95
includes taxes & fees
3 May - 4 May
Shangri-La Springs
Exterior

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
1.7 mi from Siesta Isle
9.2 out of 10, Wonderful, (1,015 reviews)
"Amazing property! Ernesto was an absolute gem helping has throughout our stay"
Canada
Carlton
The price is £77
includes taxes & fees
23 Apr - 24 Apr
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Garden

Fairways Inn of Naples

Fairways Inn of Naples
3.0 star property
17.7 mi from Siesta Isle
9.4 out of 10, Exceptional, (1,267 reviews)
"Great room, Great breakfast too "
United States
Dirk
The price is £73
includes taxes & fees
22 Apr - 23 Apr
Fairways Inn of Naples
1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
9.5 mi from Siesta Isle
7.4 out of 10, Good, (293 reviews)
"Breakfast fine, parking ok , all good"
United Kingdom
Martin
The price is £67
includes taxes & fees
19 Apr - 20 Apr
Quality Inn Fort Myers Cape Coral
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.
Sunset on the island of Sanibel.Florida.USA

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

Seashells shelling activity on shell beach in Sanibel, Fort Myers , South Florida banner panorama background, USA travel.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

fort myers beach before hurricane Ian

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

einsamer Strand in einer Lagune in Fort Myers

Laguna Shores

While Laguna Shores may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lover's Key Beach and Santini Marina Shopping Plaza.

Top Siesta Isle Hotel Reviews

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

10/10 Excellent
"Loved the garden and breakfast area! Definitely will stay here again!"
Jeffrey 1-night trip
Posted 10 hours ago
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Frequently asked questions

What are the best hotels in Siesta Isle that travellers recommend?
For a highly recommended hotel in Siesta Isle, consider the Latitude 26 Waterfront Boutique Resort - Fort Myers Beach.

This resort has an 8.8 rating and offers a range of positive features. Guests frequently highlight the convenient location, the friendly staff, and the amazing pool. The rooms are often described as spacious and beautiful, and the complimentary breakfast receives good reviews. The resort also offers amenities such as air conditioning and sailing on-site, with the option for early check-in. It is conveniently located near attractions like Smugglers Cove Adventure Golf and Jungle Golf Ft. Myers.

Overall, it is an excellent choice for a pleasant stay in Siesta Isle.
What are the best family hotels in Siesta Isle?
For a family-friendly accommodation in Siesta Isle, consider the Latitude 26 Waterfront Boutique Resort - Fort Myers Beach.

This resort, with a strong rating of 8.8, is popular by guests for its convenient location and friendly staff. Families will appreciate the availability of free cribs, sofa beds, and pool toys, making it easy to travel with children. The resort also features a nice pool that guests describe as amazing, superb for relaxation and fun. The rooms are spacious and beautiful, providing ample space for families, and the breakfast receives positive feedback. For entertainment, Smugglers Cove Adventure Golf and Beach Bowl are both within a short distance, at 1.2 km and 1.0 km respectively.
What hotels in Siesta Isle offer free breakfast?
For a hotel in Siesta Isle offering complimentary breakfast, the Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is an excellent choice.

This resort, rated 8.8, provides free continental breakfast daily, a feature highly appreciated by guests. It is conveniently located near various attractions such as Smugglers Cove Adventure Golf, just 1.2 km away, and Beach Bowl, 1.0 km away. Guests consistently praise the friendly staff, spacious rooms, and the nice pool.
What are the best budget hotels in Siesta Isle?
For a highly-rated budget option in Siesta Isle, consider the Latitude 26 Waterfront Boutique Resort - Fort Myers Beach.

This resort has an 8.8 rating and offers several complimentary amenities, including free continental breakfast, free self-parking, and free WiFi. Guests appreciate the spacious and beautiful rooms, as well as the friendly staff and nice pool. It is conveniently located near attractions such as Smugglers Cove Adventure Golf and Beach Bowl.
What are the most romantic hotels in Siesta Isle for couples?
For a romantic stay in Siesta Isle, consider Latitude 26 Waterfront Boutique Resort - Fort Myers Beach.

This 3-star resort, with an 8.8 rating, is often praised by guests for its convenient location and friendly staff. Couples will appreciate the spacious and beautiful rooms, and the amazing pool. A complimentary continental breakfast is provided, and the resort is located near Bunche Beach and San Carlos Bay - Bunche Beach Preserve, offering lovely views and opportunities for seaside strolls.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Siesta Isle.
How can I save on a Siesta Isle hotel booking with Expedia?
Members always get our best prices. Find our best Siesta Isle hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Siesta Isle hotel?
Hotel prices in Siesta Isle often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.