Title: TOP Business Hotels in São Tomé Island for 2025 | Expedia.co.uk [São Tomé Island Travel Guide](https://expedia.co.uk/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.co.uk/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Holiday Rentals in São Tomé Island](https://expedia.co.uk/Sao-Tome-Island-Holiday-Rentals.d3486.Travel-Guide-HolidayRentals)[Flights to São Tomé Island](https://expedia.co.uk/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[Things to do in São Tomé Island](https://expedia.co.uk/Things-To-Do-In-Sao-Tome-Island.d3486.Travel-Guide-Activities)[São Tomé Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sao-Tome-Island.d3486.Car-Hire-Guide)[São Tomé Island Holidays](https://expedia.co.uk/Sao-Tome-Island.d3486.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/6bd54b7b17061af058501372a92d6b86.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in São Tomé Island ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on São Tomé Island Business Hotels Tonight [14 Oct - 15 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-14&endDate=2025-10-15&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [15 Oct - 16 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-15&endDate=2025-10-16&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=3486&startDate=2025-10-24&endDate=2025-10-26&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top São Tomé Island Business Hotels ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/3031ec18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/29be8553.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/74d1540a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/5242c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Praia São Tomé 7.6/10 Good (17) "This place is way over priced for no wifi and linens that seemed like they were done in the River and dried on the rocks as most São Toméans must do Not for over $150 I’ve had better everything for $15 a night in west and central Africa And no matter how much you ask for help they just smile. D DO NOTHING" [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6e33456d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/bf678cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/5dc4d7b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sweet Guest House São Tomé 8.8/10 Excellent (45) "Very clean and very well-maintained property" £43 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Sweet-Guest-House.h12336226.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/bab20d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e6d4a2d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/68d94f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/42171940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SH Boutique Hotel São Tomé 8.6/10 Excellent (10) "Staff were very accommodating " £68 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/741e11cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/fca34520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omali São Tomé – Principe Collection São Tomé 9.4/10 Exceptional (59) "The employees really make the property a superstar. " £172 includes taxes & fees 6 Nov - 7 Nov [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/0767273b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Single Beds | Desk, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/ed868ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, towels](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/184b1734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Praia Accommodation São Tomé 7.2/10 Good (17) "Great place to stay " [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5c6a7fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/709afd60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, City View | Minibar, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/03eea49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central São Tomé 8.2/10 Very good (24) "This is an excellent centrally located well-kept hotel. Close to supermarket, restaurant and sites of interest in town, Friendly staff but language can be a bit of an issue" £48 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/10340e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/4d41d0ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, Partial Sea View | Individually decorated, desk, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/2db5e3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/a0b55f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Kriola São Tomé 8.8/10 Excellent (3) "Loved the mermaids in the pool" £68 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Sao-Tome-Hotels-Hotel-Kriola.h106989405.Hotel-Information) ![Bungalow | 2 bedrooms, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/e4d8c6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow | 2 bedrooms, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/b8ac8133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/2d9f01d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic House | In-room dining](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/4670fd80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Quinta Natural Trindade 10/10 Exceptional (1) £59 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29®ionId=3486&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top São Tomé Island Hotel Reviews ![Omali São Tomé – Principe Collection](//images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg) ### Omali São Tomé – Principe Collection 8/10 Good "It’s a great resort, with friendly staff who " [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Pestana São Tomé](//images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg) ### Pestana São Tomé 8/10 Good "Good choice in São Tomé city." [](https://expedia.co.uk/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ## Frequently asked questions ### Are there any family-friendly hotels in São Tomé Island that are also business friendly? > [Mucumbli Hotel](https://www.expedia.co.uk/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information) is a great choice for families and business travellers. A nearby beach and front desk services are among the many amenities at this 3-star São Tomé Island property. Once you've wrapped up work, take the kids to São Tomé Island's top family attractions. [Pico São Tomé](https://www.expedia.co.uk/Pico-Sao-Tome-Sao-Tome-Island.d553248621532481757.Attraction) is a good place to start. ### Why book your business hotel in São Tomé Island with Expedia? > Here at Expedia, it's our job to help you locate a suitable stay at the right price. From 5-star corporate-friendly properties to affordable motor inns filled with handy amenities, you'll have your next work trip arranged in a couple of clicks. ### How can I find cheap business hotels in São Tomé Island? > Expedia can help you easily locate cheap business hotels in São Tomé Island. Simply go to our "traveller experience" filter and click on "business friendly." This will show you accommodation with amenities designed to help you work effectively and comfortably, like included breakfast and free WiFi. You can also choose your hotel star rating and budget to keep costs under control. ### What is there to do in São Tomé Island near my business hotel? > Once you've settled into your hotel, venture out and explore the awesome things São Tomé Island has for you to experience. 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