Santo Antonio Holidays

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Your Santo Antonio Holiday

Experience the best that Santo Antonio has to offer with a Santo Antonio holiday package. From its shopping and cafes to its culture, it's not hard to be charmed by this picturesque neighbourhood. Begin your trip to Santo Antonio with a visit to nearby attractions such as Castle of São Jorge, Rossio Square and Lisbon Cathedral. Stop daydreaming and start doing. When you're ready to lock in your next holiday to Santo Antonio, Expedia is here to help.

Top hotels in Santo Antonio

Locke de Santa Joana

Locke de Santa Joana

4 out of 5
18 Rua Camilo Castelo Branco Lisbon
Fully refundableReserve now, pay when you stay
The price is £116 per night from 29 Apr to 30 Apr
£116
29 Apr - 30 Apr
includes taxes & fees
9.4/10 Exceptional! (1,711 reviews)
Very nice vibe

Reviewed on 14 Apr 2026

Locke de Santa Joana
HF Fénix Lisboa

HF Fénix Lisboa

4 out of 5
Praca Marques de Pombal, 8 Lisbon
The price is £128 per night from 26 Apr to 27 Apr
£128
26 Apr - 27 Apr
includes taxes & fees
9.2/10 Wonderful! (1,015 reviews)
This has been the best experience ! I can’t thank enough the staff ! The breakfast was incredible ! Location close to it all !! We are coming back

Reviewed on 10 Apr 2026

HF Fénix Lisboa
EXE Liberdade

EXE Liberdade

3 out of 5
Avenida Duque de Loule 124 Lisbon
Fully refundableReserve now, pay when you stay
The price is £111 per night from 18 Apr to 19 Apr
£111
18 Apr - 19 Apr
includes taxes & fees
9/10 Wonderful! (1,165 reviews)
Good hotel

Reviewed on 12 Apr 2026

EXE Liberdade
See all 683 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Beach Holidays
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Family Friendly Holidays

Popular places to visit

Avenida da Liberdade

Avenida da Liberdade

You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the charming cafes in this family-friendly area or seek out the local tours.

Avenida da Liberdade
Marquis of Pombal Square

Marquis of Pombal Square

4/5(264 reviews)

Learn about the local history of Lisbon with a stop at Marquis of Pombal Square. Stroll along the riverfront or experience the fascinating museums in this vibrant area.

Marquis of Pombal Square
Belém Tower

Belém Tower

4.5/5(786 reviews)

Belém Tower is a UNESCO World Heritage Site, located on the northern bank of the Tagus River in the Belém district of Lisbon.

Belém Tower

What to do in Santo Antonio

Almendres Cromlech circle of stones in Evora

Small-Group Day Trip to Évora & Almendres Cromlech

£62
per adult
94% of travellers recommend
Small-Group Day Trip to Évora & Almendres Cromlech
Small Group Tour to Sintra, Pena Palace, Cabo Roca and Cascais

Small Group Tour to Sintra, Pena Palace, Cabo Roca and Cascais

£57
per adult
98% of travellers recommend
Small Group Tour to Sintra, Pena Palace, Cabo Roca and Cascais
Tastes & Traditions of Lisbon Food Tour

Tastes & Traditions of Lisbon Food Tour

£69
per adult
100% of travellers recommend
Tastes & Traditions of Lisbon Food Tour
See all activities in Santo Antonio

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.