Santo Antonio Holidays from £261

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to £335 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Packages with flights are ATOL protected

Your Santo Antonio Holiday

Experience the best that Santo Antonio has to offer with a Santo Antonio holiday package. From its shopping and cafes to its culture, it's not hard to be charmed by this picturesque neighbourhood. Begin your trip to Santo Antonio with a visit to nearby attractions such as Castle of São Jorge, Rossio Square and Lisbon Cathedral. Stop daydreaming and start doing. When you're ready to lock in your next holiday to Santo Antonio, Expedia is here to help.

Top Santo Antonio Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Sitio dos Cavaleiros Apartments

Sitio dos Cavaleiros Apartments

4 out of 5
Lisbon Old Town
per person
13 Oct - 17 Oct
found 1 day ago
Return flight included
London (LON) to Lisbon (LIS)
9.6/10 Exceptional! (55 reviews)
A great stay! Great and helpful staff and they cleaned every day. My only comment is to replace dirty towels--used ones on the floor were hung up again on the racks.

Reviewed on 24 Apr 2025

Rossio Terrace

Rossio Terrace

2 out of 5
Lisbon City Center
per person
8 Oct - 12 Oct
found 1 day ago
Return direct flight included
Manchester (MAN) to Lisbon (LIS)
No reviews
Casa Rosário : Three Bedroom Villa with Private Pool;

Casa Rosário : Three Bedroom Villa with Private Pool;

4 out of 5
per person
14 Sept - 19 Sept
found 1 day ago
Return flight included
London (LTN) to Lisbon (LIS)
No reviews
Blue Tide - Two Bedroom Apartment

Blue Tide - Two Bedroom Apartment

3 out of 5
per person
8 Sept - 13 Sept
found 1 day ago
Return flight included
London (LON) to Lisbon (LIS)
No reviews
Sintra Marmoris Camelia

Sintra Marmoris Camelia

4 out of 5
Santa Maria e São Miguel
per person
14 Oct - 19 Oct
found 12 hours ago
Return flight included
London (LGW) to Lisbon (LIS)
10/10 Exceptional! (222 reviews)
Very clean! Great breakfast! Perfect location! Room and bathroom were great size!

Reviewed on 11 Jul 2025

Top hotels in Santo Antonio

Locke de Santa Joana

Locke de Santa Joana

4 out of 5
18 Rua Camilo Castelo Branco, Lisbon
Fully refundableReserve now, pay when you stay
The price is £105 per night from 10 Aug to 11 Aug
£105
10 Aug - 11 Aug
includes taxes & fees
9.4/10 Exceptional! (1,148 reviews)
"The property has great dining options.The dining staff is excellent.Didn't like their checkin policy. They were too exact. No room for kindness to their guests. Even if they have a room you have to wait until 4pm to get somewhere to rest after a long flight or you pay 30Euros extra. My week stay ..."

Reviewed on 27 Jul 2025

Locke de Santa Joana
EPIC SANA Marques Hotel

EPIC SANA Marques Hotel

5 out of 5
Avenida Fontes de Pereira de Melo, 8, Lisbon
Fully refundableReserve now, pay when you stay
The price is £284 per night from 8 Aug to 9 Aug
£284
8 Aug - 9 Aug
includes taxes & fees
9.6/10 Exceptional! (1,082 reviews)
"Nice hotel."

Reviewed on 29 Jul 2025

EPIC SANA Marques Hotel
easyHotel Lisbon

easyHotel Lisbon

2 out of 5
R. de Santa Marta 60, Lisbon
Fully refundableReserve now, pay when you stay
The price is £68 per night from 10 Aug to 11 Aug
£68
10 Aug - 11 Aug
includes taxes & fees
8.6/10 Excellent! (1,368 reviews)
Great Staff: Tight Quarters
"Staff was incredibly helpful and friendly. Rooms were very tight for two adults."

Reviewed on 28 Jul 2025

easyHotel Lisbon
See all 750 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Avenida da Liberdade

Avenida da Liberdade

You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the top-notch restaurants in this romantic area or seek out the local tours.

Avenida da Liberdade
Belem Tower which includes general coastal views, a bridge and a sunset

Belém Tower

4.5/5(779 reviews)

Belém Tower is a UNESCO World Heritage Site, located on the northern bank of the Tagus River in the Belém district of Lisbon.

Belém Tower
Marquis of Pombal Square

Marquis of Pombal Square

4/5(259 reviews)

Learn about the local history of Lisbon with a stop at Marquis of Pombal Square. Stroll along the riverfront or experience the acclaimed art galleries in this culturally rich area.

Marquis of Pombal Square

What to do in Santo Antonio

Tuk tuk tour in Lisbon historical center.

Lisbon: 5-Hour All Inclusive Tour on a Exclusive Tuk Tour

£43
per adult
Lisbon: 5-Hour All Inclusive Tour on a Exclusive Tuk Tour
Sintra, Pena Palace, Cabo da Roca Coast & Cascais Full Day Tour

Sintra, Pena Palace and Cascais Full Day Tour from Lisbon

£40
per adult
96% of travellers recommend
Sintra, Pena Palace and Cascais Full Day Tour from Lisbon
Óbidos is a medieval town with cobblestone streets and flower-bedecked, whitewashed houses

Full-day Fátima, Nazaré, and Óbidos Small-Group Tour from Lisbon

£69
per adult
98% of travellers recommend
Full-day Fátima, Nazaré, and Óbidos Small-Group Tour from Lisbon
See all activities in Santo Antonio

Frequently asked questions

How much does a Santo Antonio travel package cost?
Much less than you might think — from as low as £261, actually! By bundling flights, hotels and car rentals into your own custom-built travel package, your getaway to Santo Antonio is just clicks away.
If I'm not able to travel, can I cancel my Santo Antonio travel package?
If your holiday plans in Santo Antonio have been upended, it's good to know that you can amend or cancel your booking. If you made your booking in the last 24 hours, you may be able to get a refund. If your booking was made more than 24 hours ago, your hotel, airline or car rental company may charge a cancellation fee. For more information, visit our Customer Service Portal.
How do I get a cheap travel package to Santo Antonio?
It's easy. Just bundle everything together. Flights, rental cars and hotels — combine whatever you need into a Santo Antonio travel package to save a ton of cash. Score even bigger bargains when you add extras such as activities or tours to your booking. But that's not the only good part. You have the flexibility to customize your trip your way. We offer over 550 partner airlines and 1,000,000 hotels throughout the world, so that everyone has an opportunity to travel and live out those holiday fantasies.
Does Expedia offer Book Now, Pay Later Santo Antonio holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a fantastic getaway without exhausting your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Klarna offers manageable monthly payment plans that work for all budgets, so you can take that well-earned holiday now.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your holiday in multiple transactions.
  • Low deposit holidays: Hitting the "book now" button is easier with this payment plan. Just put down a small deposit on your holiday and then start packing your suitcase.

Where should I stay in Santo Antonio?
Urban explorers come from all over the world to experience Castle of São Jorge and Lisbon Oceanarium in Santo Antonio. Stay close to these awesome attractions to make sightseeing a breeze.
What are the top hotels in Santo Antonio?
Radisson Blu Hotel and Novotel Lisboa are two of the most popular properties in Santo Antonio. Why not look up the amenities and rates at each and then decide?
How far in advance should I book my Santo Antonio holiday?
Smart travellers will likely want to reserve their seats early. You can generally compare international airfares on Expedia up to a year before your intended flight. If you're late to book, don't worry. Low prices sometimes become available just weeks before departure dates.
What does an Expedia Santo Antonio travel package include?
With Expedia, you can choose a combination of car rentals, flights and hotels to build your perfect Santo Antonio travel package. Once you've made your booking, you can add on the fun stuff like activities and tours. Don't forget, the more you bundle, the more you'll save!
What should I know before booking a Santo Antonio travel package?
Booking all the parts of your trip together is a terrific way to save. Bundle your airfares, rental cars and hotels into a convenient little package. But you're not limited to hotels. Expedia features all sorts of properties, including holiday rentals like beachside villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Santo Antonio Expedia travel package?
Definitely. Expedia has more than 550 airline partners to select from globally. With such a big range of choice, finding the perfect carrier to get you to Santo Antonio shouldn't be hard.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.