Title: Santiago Holidays 2026 from £1,038 | Expedia.co.uk [Hotels in Santiago](https://expedia.co.uk/Santiago-Hotels.d6191486.Travel-Guide-Hotels)[Holiday Rentals in Santiago](https://expedia.co.uk/Santiago-Holiday-Rentals.d6191486.Travel-Guide-HolidayRentals)[Santiago Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santiago.d6191486.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santiago Holidays from £1,038 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your Santiago Holiday Enjoy the urban city of Santiago with a tailor-made Santiago holiday package and immerse yourself in all it can offer. From its rich history and cultural experiences to its lively atmosphere, prepare to fall for the unique charms of this vibrant destination. [Parque Acuatico Italia Guadalupe Panama](https://www.expedia.co.uk/Parque-Acuatico-Italia-Guadalupe-Panama-Santiago.d553248621555803053.Attraction), [Catedral of Santiago Apostol](https://www.expedia.co.uk/Catedral-Of-Santiago-Apostol-Santiago.d553248621562854386.Attraction) and [Plaza Banconal](https://www.expedia.co.uk/Plaza-Banconal-Santiago.d553248621562854384.Attraction) are just some of the sights you'll want to see during your trip to Santiago. A few quick clicks is all it takes to put together the perfect Santiago holiday on Expedia. ## Top Santiago Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Casa Panamá](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/6488c648_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Casa Panamá Casco Viejo £1,038 per person 3 Apr - 10 Apr found 1 day ago Return flight included Manchester (MAN) to Panama City (PTY) 7.4/10 Good! (577 reviews) Very dark and small room. Reviewed on 14 Jan 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo £1,418 per person 3 Apr - 10 Apr found 1 day ago Return flight included Manchester (MAN) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Beautiful location, lovely facility, v friendly and helpful staff Reviewed on 19 Jan 2026 ![La Concordia Boutique Hotel](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Concordia Boutique Hotel Casco Viejo £1,638 per person 3 Apr - 10 Apr found 1 day ago Return flight included Manchester (MAN) to Panama City (PTY) 9.6/10 Exceptional! (191 reviews) Great staff. Awesome rooms. The rooftop bar was INCREDIBLE! Highly recommend. Reviewed on 13 Jan 2026 ![Hotel La Compañía Casco Antiguo](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/02cb9f51_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Compañía Casco Antiguo Casco Viejo £1,785 per person 3 Apr - 10 Apr found 1 day ago Return flight included Manchester (MAN) to Panama City (PTY) 9.8/10 Exceptional! (245 reviews) Recommend that all tours and events be booked a month in advance. It was a little hard to connect with someone to book the culinary and Neri Market tour with the chef. The rooms are exquisite and high end and the decor all the way through the hotel was well appointed. I recommend the king suite in the Spanish section facing the courtyard. The 1739 wine and dinner pairing was exceptional. Highly recommend. Make sure you spend time at the pool during midday and the drinks at night on the roof top with DJ. Thanks to Brian at the front desk for setting us up with right room and thanks to Isabely’s and Ericka for the wine and pairing suggestions. The front desk was awesome with accommodations. This was a very pleasant stay can’t wait to go back. Reviewed on 29 Nov 2025 ## Santiago Essential Information | Language | Spanish | | --------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Population | 45,400 | | Max Temp Winter | 32ºC | | Max Temp Summer | 29ºC | | Top Sights | [Catedral of Santiago Apostol](https://www.expedia.co.uk/Catedral-Of-Santiago-Apostol-Santiago.d553248621562854386.Attraction), [Omar Torrijos Herrera Stadium](https://www.expedia.co.uk/Omar-Torrijos-Herrera-Stadium-Santiago.d553248621562854385.Attraction) and [Plaza Banconal](https://www.expedia.co.uk/Plaza-Banconal-Santiago.d553248621562854384.Attraction) | ## Top hotels in Santiago ![Hotel Gran David](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/5966cf9c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Gran David Vía Interamericana Santiago Veraguas Fully refundableReserve now, pay when you stay £64 27 Jan - 28 Jan includes taxes & fees 8.4/10 Very Good! (366 reviews) clean spotless and so comfortable. Reviewed on 15 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=27%2F01%2F2026&endDate=28%2F01%2F2026&selected=12003378&PinnedHotelID=12003378&HadPinnedHotel=true®ionId=6191486) ![The Spring Loft | Santiago](https://images.trvl-media.com/lodging/91000000/90300000/90295100/90295096/84988aa6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Spring Loft | Santiago Santiago Provincia de Veraguas Overnight stay, fine for being overnight, not any longer. Using toilette cannot sit down knees knock wall if you are taller than 5 foot!! Not comfortable sitting sideways on it. Making coffee… powdered substance in jar on shelf with coffee and sugar is Not!! Creamer as thought…. Rude awakening for ... Reviewed on 10 Aug 2024 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F02%2F2026&endDate=03%2F02%2F2026&selected=90295096&PinnedHotelID=90295096&HadPinnedHotel=true®ionId=6191486) [](https://expedia.co.uk/Hotel-Search?startDate=02%2F02%2F2026&endDate=03%2F02%2F2026&selected=90295096&PinnedHotelID=90295096&HadPinnedHotel=true®ionId=6191486) ![Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone](https://images.trvl-media.com/lodging/110000000/109330000/109329300/109329235/ec2faad8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone Santiago Provincia de Veraguas [Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F02%2F2026&endDate=03%2F02%2F2026&selected=109329235&PinnedHotelID=109329235&HadPinnedHotel=true®ionId=6191486) [](https://expedia.co.uk/Hotel-Search?startDate=02%2F02%2F2026&endDate=03%2F02%2F2026&selected=109329235&PinnedHotelID=109329235&HadPinnedHotel=true®ionId=6191486) [See all 14 properties in Santiago](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=20%2F01%2F2026&endDate=21%2F01%2F2026®ionId=6191486) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit #### Escuela Normal Juan Demostenes Arosemena Take a campus tour or just explore the area of Escuela Normal Juan Demostenes Arosemena during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area. [](https://expedia.co.uk/Escuela-Normal-Juan-Demostenes-Arosemena-Santiago.d553248621562854387.Attraction) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app