Title: Hotels in Santiago del Río - Best Santiago del Río Hotels from £66 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santiago del Río](https://expedia.co.uk/Santiago-Del-Rio-Holiday-Rentals.d553248635640665145.Travel-Guide-HolidayRentals)[Santiago del Río Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santiago-Del-Rio.d553248635640665145.Car-Hire-Guide)[Santiago del Río Holidays](https://expedia.co.uk/Santiago-Del-Rio.d553248635640665145.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santiago del Río from £66 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [27 Nov - 28 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640665145&startDate=2025-11-27&endDate=2025-11-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Nov - 29 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640665145&startDate=2025-11-28&endDate=2025-11-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640665145&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640665145&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santiago del Río hotels and places to stay ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248635640665145) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels) ## Top Santiago del Río Hotel Reviews ## More cheap stays in Santiago del Río ![HOTEL POSADA DON MATIAS](https://images.trvl-media.com/lodging/110000000/109630000/109623100/109623058/cd4c38fa_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL POSADA DON MATIAS 316 C. de Ignacio Aldama Centro Oaxaca OAX [Get rates](https://expedia.co.uk/Hotel-Search?startDate=11%2F12%2F2025&endDate=12%2F12%2F2025&selected=109623058&PinnedHotelID=109623058&HadPinnedHotel=true®ionId=553248635640665145) 9/10 Wonderful! (173 reviews) [](https://expedia.co.uk/Oaxaca-Hotels-HOTEL-POSADA-DON-MATIAS.h109623058.Hotel-Information) ![Casona Oaxaca Historia y Paz](https://images.trvl-media.com/lodging/108000000/107620000/107611700/107611619/49b3b44d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casona Oaxaca Historia y Paz Trujano 206 Oaxaca Oax. £72 11 Dec - 12 Dec includes taxes & fees 9.2/10 Wonderful! (158 reviews) [](https://expedia.co.uk/Oaxaca-Hotels-Casona-Oaxaca-Historia-Y-Paz.h107611619.Hotel-Information) ![Blater Hotel](https://images.trvl-media.com/lodging/16000000/15260000/15251800/15251774/a74d6916_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Blater Hotel Calle Del Morro S/N Col. Santa Maria Santa Maria Colotepec Oaxaca £106 6 Dec - 7 Dec includes taxes & fees 9.2/10 Wonderful! (49 reviews) [](https://expedia.co.uk/Santa-Maria-Colotepec-Hotels-Blater-Hotel.h15251774.Hotel-Information) ![HOTEL BIULÚ](https://images.trvl-media.com/lodging/91000000/90950000/90946300/90946251/7f6d4e14_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL BIULÚ BOULEVARD BENITO JUAREZ, 22 Santa María Huatulco OAX £66 29 Nov - 30 Nov includes taxes & fees 8.8/10 Excellent! (131 reviews) [](https://expedia.co.uk/Santa-Maria-Huatulco-Hotels-HOTEL-BIULU.h90946251.Hotel-Information) ![Happy Express Hotel](https://images.trvl-media.com/lodging/10000000/9590000/9587300/9587247/820d5b66_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Happy Express Hotel Diaz Ordaz 312 Oaxaca OAX [Get rates](https://expedia.co.uk/Hotel-Search?startDate=11%2F12%2F2025&endDate=12%2F12%2F2025&selected=9587247&PinnedHotelID=9587247&HadPinnedHotel=true®ionId=553248635640665145) 9/10 Wonderful! (314 reviews) [](https://expedia.co.uk/Oaxaca-Hotels-Happy-Express-Hotel.h9587247.Hotel-Information) ![Hotel Posada El Cid](https://images.trvl-media.com/lodging/12000000/11600000/11592000/11591984/05e73c87_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Posada El Cid Pino Suarez 903, Colonia Centro Oaxaca OAX [Get rates](https://expedia.co.uk/Hotel-Search?startDate=11%2F12%2F2025&endDate=12%2F12%2F2025&selected=11591984&PinnedHotelID=11591984&HadPinnedHotel=true®ionId=553248635640665145) 7.8/10 Good! (67 reviews) [](https://expedia.co.uk/Oaxaca-Hotels-Posada-Del-Cid.h11591984.Hotel-Information) ## Frequently asked questions ### If I need to cancel my hotel reservation in Santiago del Río, will I receive a refund? > Yes, most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640665145&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santiago del Río. ### What's the seasonal weather like in Santiago del Río? > The hottest months are usually April and May, with an average temperature of 20°C, while the coldest months are January and December, with an average of 16°C. The rainiest months in Santiago del Río are September, August, June and July, with each month seeing an average of 305 mm of rainfall. ## Explore a world of travel with Expedia - Accommodation - Packages - Cars - More ways to book - [Chalcatongo de Hidalgo Hotels](https://www.expedia.co.uk/Chalcatongo-De-Hidalgo-Hotels.d553248635640677829.Travel-Guide-Hotels) - [Huajuapan Hotels](https://www.expedia.co.uk/Huajuapan-Hotels.d6245105.Travel-Guide-Hotels) - [Mártires de Tacubaya Hotels](https://www.expedia.co.uk/Martires-De-Tacubaya-Hotels.d553248635640678277.Travel-Guide-Hotels) - [Pinotepa de Don Luis Hotels](https://www.expedia.co.uk/Pinotepa-De-Don-Luis-Hotels.d553248635640692183.Travel-Guide-Hotels) - [Pinotepa Nacional Hotels](https://www.expedia.co.uk/Pinotepa-Nacional-Hotels.d3000449713.Travel-Guide-Hotels) - [Putla Villa de Guerrero Hotels](https://www.expedia.co.uk/Putla-Villa-De-Guerrero-Hotels.d553248635640677765.Travel-Guide-Hotels) - [Reyes Etla Hotels](https://www.expedia.co.uk/Reyes-Etla-Hotels.d553248634245938425.Travel-Guide-Hotels) - [San Antonio Acutla Hotels](https://www.expedia.co.uk/San-Antonio-Acutla-Hotels.d553248635640662146.Travel-Guide-Hotels) - [San Jorge Nuchita Hotels](https://www.expedia.co.uk/San-Jorge-Nuchita-Hotels.d553248635640681158.Travel-Guide-Hotels) - [San Juan Bautista Lo de Soto Hotels](https://www.expedia.co.uk/San-Juan-Bautista-Lo-De-Soto-Hotels.d553248635640642903.Travel-Guide-Hotels) - [San Juan Cacahuatepec Hotels](https://www.expedia.co.uk/San-Juan-Cacahuatepec-Hotels.d553248635640656455.Travel-Guide-Hotels) - [San Miguel Ahuehuetitlán Hotels](https://www.expedia.co.uk/San-Miguel-Ahuehuetitlan-Hotels.d553248635640637554.Travel-Guide-Hotels) - [San Pedro y San Pablo Teposcolula Hotels](https://www.expedia.co.uk/San-Pedro-Y-San-Pablo-Teposcolula-Hotels.d553248635640657811.Travel-Guide-Hotels) - [Santa Cruz Tacache de Mina Hotels](https://www.expedia.co.uk/Santa-Cruz-Tacache-De-Mina-Hotels.d553248635640668519.Travel-Guide-Hotels) - [Santa María Tecomavaca Hotels](https://www.expedia.co.uk/Santa-Maria-Tecomavaca-Hotels.d553248635640676421.Travel-Guide-Hotels) - [Santiago Amoltepec Hotels](https://www.expedia.co.uk/Santiago-Amoltepec-Hotels.d553248635640631700.Travel-Guide-Hotels) - [Santiago Apoala Hotels](https://www.expedia.co.uk/Santiago-Apoala-Hotels.d553248635640634931.Travel-Guide-Hotels) - [Santiago Chazumba Hotels](https://www.expedia.co.uk/Santiago-Chazumba-Hotels.d553248635640665915.Travel-Guide-Hotels) - [Santiago Juxtlahuaca Hotels](https://www.expedia.co.uk/Santiago-Juxtlahuaca-Hotels.d553248635640672179.Travel-Guide-Hotels) - [Santiago Tamazola Hotels](https://www.expedia.co.uk/Santiago-Tamazola-Hotels.d553248635640637097.Travel-Guide-Hotels) - [Santo Domingo Tonala Hotels](https://www.expedia.co.uk/Santo-Domingo-Tonala-Hotels.d3000437018.Travel-Guide-Hotels) - [Tamazulapam Hotels](https://www.expedia.co.uk/Tamazulapam-Hotels.d6320679.Travel-Guide-Hotels) - [Tataltepec de Valdés Hotels](https://www.expedia.co.uk/Tataltepec-De-Valdes-Hotels.d553248635640660890.Travel-Guide-Hotels) - [Teotitlán de Flores Magón Hotels](https://www.expedia.co.uk/Teotitlan-De-Flores-Magon-Hotels.d553248635640632888.Travel-Guide-Hotels) - [Tlaxiaco Hotels](https://www.expedia.co.uk/Tlaxiaco-Hotels.d3000367158.Travel-Guide-Hotels) - [Villa Tejúpam de la Unión Hotels](https://www.expedia.co.uk/Villa-Tejupam-De-La-Union-Hotels.d553248635640642299.Travel-Guide-Hotels) - [Visit Huajuapan](https://www.expedia.co.uk/Huajuapan.dx6245105) - [Visit Magdalena Apasco](https://www.expedia.co.uk/Magdalena-Apasco.dx553248635640675660) - [Visit Magdalena Peñasco](https://www.expedia.co.uk/Magdalena-Penasco.dx553248635640700820) - [Visit Pinotepa Nacional](https://www.expedia.co.uk/Pinotepa-Nacional.dx3000449713) - [Visit Putla Villa de Guerrero](https://www.expedia.co.uk/Putla-Villa-De-Guerrero.dx553248635640677765) - [Visit San Agustín Atenango](https://www.expedia.co.uk/San-Agustin-Atenango.dx553248635640694617) - [Visit San Juan Bautista Cuicatlán](https://www.expedia.co.uk/San-Juan-Bautista-Cuicatlan.dx553248635640632624) - [Visit San Juan Bautista Jayacatlán](https://www.expedia.co.uk/San-Juan-Bautista-Jayacatlan.dx553248635640673670) - [Visit San Pablo Cuatro Venados](https://www.expedia.co.uk/San-Pablo-Cuatro-Venados.dx553248635640700437) - [Visit San Pablo Huitzo](https://www.expedia.co.uk/San-Pablo-Huitzo.dx553248635640633619) - [Visit San Pedro Mártir Yucuxaco](https://www.expedia.co.uk/San-Pedro-Martir-Yucuxaco.dx553248635640665187) - [Visit Santa Catarina Zapoquila](https://www.expedia.co.uk/Santa-Catarina-Zapoquila.dx553248635640704493) - [Visit Santa Magdalena Jicotlán](https://www.expedia.co.uk/Santa-Magdalena-Jicotlan.dx553248635640675874) - [Visit Santiago Yucuyachi](https://www.expedia.co.uk/Santiago-Yucuyachi.dx553248635640633085) - [Visit Santo Domingo Teojomulco](https://www.expedia.co.uk/Santo-Domingo-Teojomulco.dx553248635640678296) - [Visit Santo Tomás Mazaltepec](https://www.expedia.co.uk/Santo-Tomas-Mazaltepec.dx553248635640678564) - [Visit Tepelmeme Villa de Morelos](https://www.expedia.co.uk/Tepelmeme-Villa-De-Morelos.dx553248635640641962) - [Visit Tlaxiaco](https://www.expedia.co.uk/Tlaxiaco.dx3000367158) - [Visit Zapotitlán Lagunas](https://www.expedia.co.uk/Zapotitlan-Lagunas.dx553248635640678078) - [Car hire San Francisco Jaltepetongo](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Francisco-Jaltepetongo.d553248635640670981.Car-Hire-Guide) - [Book Hotels in Santiago del Río on Expedia.mx](https://www.expedia.mx/Santiago-Del-Rio-Hoteles.d553248635640665145.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)