Santee Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Santee Essential Information

Language
English
Currency
U.S dollars
Max Temp Winter
-1.11ºC
Max Temp Summer
29ºC

Top hotels in Santee

Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive Yankton SD
The price is £90 per night from 1 Nov to 2 Nov
£90
1 Nov - 2 Nov
includes taxes & fees
Lewis and Clark Resort
Charming Lake House within Walking Distance from Lake

Charming Lake House within Walking Distance from Lake

Yankton SD
9.6/10 Exceptional! (47 reviews)
"It was a great place to stay , it was nice the kids had their own area to hang out"

Reviewed on 9 Sept 2026

Get rates
Charming Lake House within Walking Distance from Lake
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Crofton NE
The price is £903 per night from 3 Nov to 4 Nov
£903
3 Nov - 4 Nov
includes taxes & fees
10/10 Exceptional! (11 reviews)
"Family friendly"

Reviewed on 25 Oct 2026

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
See all 67 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santee travel package cost?
Our Santee travel packages, which start at just , are the perfect way to save big. Pick your preferred hotels, flights and more to create a custom-built itinerary.
If I'm not able to travel, can I cancel my Santee travel package?
Yes, you can. We get that things don't always go to plan, so we're happy to help if you need to make changes to your Santee travel package. You may be able to amend or cancel your itinerary at no cost if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Look up our Customer Service Portal for more information. Also, be sure to check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to Santee?
You'll save piles of cash if you combine your hotels, car rentals and flights into a Santee holiday package. Sometimes cheap packages mean fewer choices. But that's not the case with Expedia. We offer more than 550 air carriers and 1,000,000 hotels throughout the world, so you'll always have plenty of variety to choose from. Eager to save even more? Add some popular activities to your package deal and unlock even bigger bargains! After all, travel is about more than just getting to your destination.
Does Expedia offer Book Now, Pay Later Santee holidays?
Expedia has partnered with online lender Klarna to make your next break easier on your wallet. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that suits your budget. Take a look at these flexible payment options:

  • Pay monthly holidays: Klarna offers easy monthly payment plans that work for all budget sizes, so you can book that well-earned holiday now.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Then go for this Book Now, Pay Later option from Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, go for a low deposit holiday payment plan from Klarna.

How far in advance should I book my Santee holiday?
Be rewarded with the widest variety at the lowest prices by booking your adventure to Santee nice and early. Air carriers typically release flight tickets around a year in advance, so secure your spot as soon as possible. That said, Expedia is dedicated to giving you the best bargains around, so it's always a good time to book your dream holiday!
What does an Expedia Santee travel package include?
It's up to you! You can select from a range of Santee packages, such as a flight, hotel and rental car. You can also book a flight and a hotel, or a rental car with a flight. Once you've made your booking, you can add on the fun stuff like experiences and tours. Whatever your dream Santee getaway looks like, you're sure to save!
What should I know before booking a Santee travel package?
When you book your hotels, flights and car rentals together, you'll walk away with incredible discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a fancy hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Santee Expedia travel package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines throughout the world. Our travel packages give you the flexibility to pick from available flight, hotel or activity options that fit your needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.