Title: Santee Holidays 2026 | Expedia.co.uk [Hotels in Santee](https://expedia.co.uk/Santee-Hotels.d553248634983588478.Travel-Guide-Hotels)[Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d553248634983588478.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d553248634983588478.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Santee Holidays ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=PKG_SPRING_PROMO_553248634983588478) ## Santee Essential Information | Language | English | | --------------- | ----------- | | Currency | U.S dollars | | Max Temp Winter | \-1.11ºC | | Max Temp Summer | 29ºC | ## Top hotels in Santee ![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lewis and Clark Resort 43496 Shore Drive Yankton SD £66 3 Mar - 4 Mar includes taxes & fees 8.8/10 Excellent! (292 reviews) Clean room. Beautiful location. Comfortable stay Reviewed on 21 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=11267995&PinnedHotelID=11267995&HadPinnedHotel=true®ionId=553248634983588478) ![Charming Lake House within Walking Distance from Lake](https://images.trvl-media.com/lodging/28000000/27120000/27116700/27116625/d37f9a63_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Charming Lake House within Walking Distance from Lake Yankton SD 9.6/10 Exceptional! (37 reviews) Nice place, lots of space. Different areas to hang out, play games, watch TV. Nice outdoor patio area. Good location, easy access to Lewis & Clark recreation area. Reviewed on 30 Oct 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=27116625&PinnedHotelID=27116625&HadPinnedHotel=true®ionId=553248634983588478) [](https://expedia.co.uk/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=27116625&PinnedHotelID=27116625&HadPinnedHotel=true®ionId=553248634983588478) ![Haven by the Lake](https://images.trvl-media.com/lodging/83000000/82960000/82951700/82951676/77c0b851_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Haven by the Lake Yankton SD 10/10 Exceptional! (22 reviews) GREAT HOST! Reviewed on 24 Nov 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=82951676&PinnedHotelID=82951676&HadPinnedHotel=true®ionId=553248634983588478) [](https://expedia.co.uk/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=82951676&PinnedHotelID=82951676&HadPinnedHotel=true®ionId=553248634983588478) [See all 59 properties in Santee](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=01%2F03%2F2026&endDate=02%2F03%2F2026®ionId=553248634983588478) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app