Title: Hotels in Santee, NE - Best Santee Hotels - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d553248634983588478.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d553248634983588478.Car-Hire-Guide)[Santee Holidays](https://expedia.co.uk/Santee.d553248634983588478.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santee, NE ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santee Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+Nebraska%2C+United+States+of+America®ionId=553248634983588478&latLong=42.84111%2C-97.850901&adults=2&startDate=2025-10-27&d1=2025-10-27&endDate=2025-10-29&d2=2025-10-29&amenities=PETS) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+Nebraska%2C+United+States+of+America®ionId=553248634983588478&latLong=42.84111%2C-97.850901&adults=2&startDate=2025-10-27&d1=2025-10-27&endDate=2025-10-29&d2=2025-10-29&lodging=CABIN) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+Nebraska%2C+United+States+of+America®ionId=553248634983588478&latLong=42.84111%2C-97.850901&adults=2&startDate=2025-10-27&d1=2025-10-27&endDate=2025-10-29&d2=2025-10-29&travelerType=family_friendly) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Santee%2C+Nebraska%2C+United+States+of+America®ionId=553248634983588478&latLong=42.84111%2C-97.850901&adults=2&startDate=2025-10-27&d1=2025-10-27&endDate=2025-10-29&d2=2025-10-29&amenities=WATER_PARK) ## Check prices for these dates Tonight [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983588478&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [14 Oct - 15 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983588478&startDate=2025-10-14&endDate=2025-10-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983588478&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983588478&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santee hotels and places to stay ![32-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/58d56b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/82dbed8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Lake View, Lakeside | Living area | 32-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/ca1ac849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lewis and Clark Resort Yankton 8.8/10 Excellent (268) "nice place" [](https://www.expedia.co.uk/Vermillion-Hotels-Lewis-And-Clark-Resort.h11267995.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=553248634983588478&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d553248634983588478.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d553248634983588478.Travel-Guide-Hotels) ## Top Santee Hotel Reviews ![1two bedroom cabins that can be rented for one night or not.](//images.trvl-media.com/lodging/115000000/114490000/114488800/114488772/w2048h1254x0y0-fb6eb671_y.jpg) ### 1two bedroom cabins that can be rented for one night or not. 10/10 Excellent "Stay was great. I would recommend staying there. Rooms are clean and we loved the amenities. If I’m in the area again i will seeing if they have openings " [](https://expedia.co.uk/Crofton-Hotels-1two-Bedroom-Cabins-That-Can-Be-Rented-For-One-Night-Or-Not.h114488772.Hotel-Information) ![Lewis and Clark Resort](//images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a_y.jpg) ### Lewis and Clark Resort 10/10 Excellent "Great accommodations" [](https://expedia.co.uk/Vermillion-Hotels-Lewis-And-Clark-Resort.h11267995.Hotel-Information) ![Brand new lake house with panoramic view overlooking Lewis and Clark Lake.](//images.trvl-media.com/lodging/102000000/101180000/101176100/101176031/0f8276bc_y.jpg) ### Brand new lake house with panoramic view overlooking Lewis and Clark Lake. 10/10 Excellent "Very comfortable, spacious. Great views." [](https://expedia.co.uk/Crofton-Hotels-Brand-New-Lake-House-With-Panoramic-View-Overlooking-Lewis-And-Clark-Lake.h101176031.Hotel-Information) ![Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton. ](//images.trvl-media.com/lodging/104000000/103440000/103430100/103430081/69c2489d_y.jpg) ### Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton. 10/10 Excellent "Awesome place! " [](https://expedia.co.uk/Yankton-Hotels-Lewis-Clark-Trail-Hideaway.h103430081.Hotel-Information) ![Beautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD](//images.trvl-media.com/lodging/117000000/116510000/116501100/116501093/dd2fade7_y.jpg) ### Beautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD 10/10 Excellent "It was a wonderful property about a 5 minute drive to marina. Lots of wildlife. Property was well stocked and clean. Plenty of room for everyone. The one negative was that there is no television in the living room. So if you want to watch a game or movie as a group, there is no larger space with a tv to do so. Other than that, we enjoyed our stay." [](https://expedia.co.uk/Yankton-Hotels-Beautiful-Log-Cabin.h116501093.Hotel-Information) ![Gavins Point Lakehouse](//images.trvl-media.com/lodging/117000000/116490000/116488100/116488080/0ef95485_y.jpg) ### Gavins Point Lakehouse 10/10 Excellent "Property was stunning. Views from the home are stunning and the memories we made were u forgettable. Beds and pillows were all comfortable and the kitchen was stocked with the tools to allow you to prepare whatever upur heart desired. Communication was simple and responses were quick. Definitely a 5 star in Yankton - we have stayed in countless Vrbos in Yankton and this just raised the bar. She’s stunning!" [](https://expedia.co.uk/Yankton-Hotels-Gavins-Point-Lakeshore-Home-Inside-Lewis-Clark-State-Park-Yankton.h116488080.Hotel-Information) ![The Copper Lodge in Springfield](//images.trvl-media.com/lodging/50000000/49320000/49314600/49314574/034660c2_y.jpg) ### The Copper Lodge in Springfield 10/10 Excellent "great place to stay nice and clean great location to fishing ponds and other attractions." [](https://expedia.co.uk/The-Copper-Lodge-In-Springfield.h49314574.Hotel-Information) ![Spacious Lakeview Cabin Minutes from Private Beach](//images.trvl-media.com/lodging/105000000/104180000/104179200/104179194/w902h683x61y0-0a0c6d21_y.jpg) ### Spacious Lakeview Cabin Minutes from Private Beach 10/10 Excellent "Great location. Plenty of room for 10 adults to relax inside and outside on the deck. Owner very responsive with questions submitted. " [](https://expedia.co.uk/Crofton-Hotels-Spacious-Lakeview-Cabin-Minutes-From-Private-Beach.h104179194.Hotel-Information) ## More cheap stays in Santee ![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lewis and Clark Resort 43496 Shore Drive, Yankton, SD [Get rates](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=11267995&PinnedHotelID=11267995&HadPinnedHotel=true®ionId=553248634983588478) 8.6/10 Excellent! (264 reviews) [](https://expedia.co.uk/Vermillion-Hotels-Lewis-And-Clark-Resort.h11267995.Hotel-Information) ## Frequently asked questions ### What are some of the best holiday rentals that Santee has to offer? > [Gavins Point Lakehouse](https://www.expedia.co.uk/Yankton-Hotels-Gavins-Point-Lakeshore-Home-Inside-Lewis-Clark-State-Park-Yankton.h116488080.Hotel-Information): This holiday home rental outside of Santee offers a fireplace, a balcony and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all [vacation rentals in Santee](https://www.expedia.co.uk/Santee-Holiday-Rentals.d553248634983588478.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Santee, will I receive a refund? > Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983588478&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santee. ### What is staying in Santee like? > Those travelling to Santee will definitely enjoy the sights to see and things to do. There are 61 hotels and other accommodation options in the surrounding area. Find out more about [Santee](https://www.expedia.co.uk/Santee.dx553248634983588478). ### What is there to see in Santee? > A favourite place to visit is [Lewis and Clark Lake](https://www.expedia.co.uk/Lewis-And-Clark-Lake-United-States-of-America.d553248635976196329.Attraction). You'll also find [Niobrara State Park](https://www.expedia.co.uk/Niobrara-State-Park-Nebraska.d553248621532648826.Attraction) and [Lewis and Clark Recreation Area](https://www.expedia.co.uk/Lewis-And-Clark-Recreation-Area-South-Dakota.d553248621593151470.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Santee guide](https://www.expedia.co.uk/Santee.dx553248634983588478). ### What's the seasonal weather in Santee? > The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -3°C. 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