A valley with a town nestled between hills, a winding road, and distant mountains.

Search Holiday Homes in Santee

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
16 Oct - 18 Oct
In two months
27 Nov - 29 Nov
In three months
25 Dec - 27 Dec
In four months
22 Jan - 24 Jan

Our top choices for Santee holiday homes

A hotel with a large building, a pond with rocks and plants, and a bridge.

1. Private Casita located near San Diego attractions with free onsite laundry

Private Casita located near San Diego attractions with free onsite laundry
Lakeside
9.8 out of 10, Exceptional, (7 reviews)
"We had an amazing stay! Beautiful home with a beautiful view. Brent and Carla were very responsive to any questions. My wife and 12 month old stayed for 3 nights and we had everything we needed. The house is also very baby friendly!"
United States
Daniel C.
The price is £245
includes taxes & fees
7 Oct - 8 Oct
Private Casita located near San Diego attractions with free onsite laundry
Private kitchen

2. Spacious 4-bedroom house with AC, fitness equipment in wonderful Lakeside

Spacious 4-bedroom house with AC, fitness equipment in wonderful Lakeside
Lakeside
9.6 out of 10, Exceptional, (7 reviews)
"From the check in process to the stay it was a great experience . The house was clean and well stocked with everything needed to enjoy our stay"
United States
Timothy C.
The price is £475
includes taxes & fees
4 Oct - 5 Oct
Spacious 4-bedroom house with AC, fitness equipment in wonderful Lakeside
A gravel pathway with red bricks leading to a gate.

3. La Casita Guest House, private fenced yard & with heat and AC, pet friendly

La Casita Guest House, private fenced yard & with heat and AC, pet friendly
Mount Helix
9.8 out of 10, Exceptional, (13 reviews)
"Thank you so much for the hospitality and your kindness"
United States
Lisa D.
The price is £246
includes taxes & fees
5 Oct - 6 Oct
La Casita Guest House, private fenced yard & with heat and AC, pet friendly
A modern hotel room with a large bed, a TV, a desk, and a bathroom visible through an open door.

4. Family Haven: Sports Court, Game Room, King Beds

Family Haven: Sports Court, Game Room, King Beds
Fletcher Hills
10.0 out of 10, Exceptional, (6 reviews)
"Wonderful stay - kids had an amazing time in the game room/garage."
United States
Calvin C.
The price is £579
includes taxes & fees
7 Oct - 8 Oct
Family Haven: Sports Court, Game Room, King Beds
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table with upholstered chairs.

5. La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.0 out of 10, Wonderful, (11 reviews)
"The property was well located for us. "
United States
Ann D.
The price is £405
includes taxes & fees
7 Oct - 8 Oct
La Mesa Family Retreat - 20 minutes to Beaches & More!
A poolside area with wicker chairs, a table with a bottle and glasses, and a view of a building and pool at dusk.

6. Ultimate Group Getaway—Pool, Spa, Views, Games!

Ultimate Group Getaway—Pool, Spa, Views, Games!
San Carlos
9.6 out of 10, Exceptional, (33 reviews)
"Wonderful little oasis - so great for our family gathering with young children"
United States
Steven N.
The price is £651
includes taxes & fees
18 Oct - 19 Oct
Ultimate Group Getaway—Pool, Spa, Views, Games!
A pool with a waterfall feature, surrounded by lounge chairs and a patio area.

7. The Outside Inn at The Tipsy Goat Ranch

The Outside Inn at The Tipsy Goat Ranch
Lakeside
10.0 out of 10, Exceptional, (29 reviews)
"Wonderful stay! Beautiful property and awesome staff! We would love to come back!"
United States
Angela
The price is £225
includes taxes & fees
7 Oct - 8 Oct
The Outside Inn at The Tipsy Goat Ranch
A living room with a beige sofa, two armchairs, a coffee table, and a rug. There are two lamps, a painting on the wall, and a window with a view of greenery and a blue car outside.

8. 'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
Encanto
8.8 out of 10, Excellent, (40 reviews)
"Beds were very comfortable."
United States
Paula
The price is £194
includes taxes & fees
12 Oct - 13 Oct
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
A deck with two wicker chairs and a small table, overlooking a mountainous landscape and a body of water.

9. Luxury Studio with Lake Views and Spacious Balcony

Luxury Studio with Lake Views and Spacious Balcony
Spring Valley
7.8 out of 10, Good, (7 reviews)
"It was beautiful and very modern. We loved it and hope to come back again!! "
United States
Ronette B.
The price is £158
includes taxes & fees
2 Nov - 3 Nov
Luxury Studio with Lake Views and Spacious Balcony
A living room with a blue sofa, a round coffee table, and a world map on the wall.

10. Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very good, (4 reviews)
"We thoroughly appreciated the communications provided by the host. Initially had a few teething issues, with the keylock code not working, and a smell in the bedroom and the living area, but this was rectified and a cleaning crew came in twice for it. Place is perfectly situated (with car use) but a bit less so if on foot, or public transportation. The laundry in the shed and the kitchen are always welcome especially as our booking was over 2 weeks long! Thanks again for a suitable stay for us!"
United States
Carlo Luis
The price is £341
includes taxes & fees
12 Oct - 13 Oct
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
A spacious kitchen with a central island, pendant lighting, and a dining area with a bench.

11. Welcoming 1-bedroom hilltop guest house with views in charming Ramona

Welcoming 1-bedroom hilltop guest house with views in charming Ramona
Ramona
10.0 out of 10, Exceptional, (2 reviews)
"Very nice place to stay in Ramona!!"
United States
Tracey L.
The price is £180
includes taxes & fees
5 Oct - 6 Oct
Welcoming 1-bedroom hilltop guest house with views in charming Ramona
A modern living room with a fireplace, a ceiling fan, and a large sliding glass door leading to an outdoor area.

12. Palm & Peace Retreat

Palm & Peace Retreat
La Mesa
9.8 out of 10, Exceptional, (20 reviews)
"The host is very responsive and the house is nice in a great location! "
United States
Demi B.
The price is £504
includes taxes & fees
4 Oct - 5 Oct
Palm & Peace Retreat
A pool with a waterfall feature, surrounded by palm trees and a thatched-roof structure.

13. Villa Paradiso

Villa Paradiso
El Cajon
9.6 out of 10, Exceptional, (25 reviews)
"Beautiful home, spacious, clean and everything we needed was right there. Swimming pool, hot tub,slide and BBQ area were off the hook. We had a great time and will definitely look into getting this place again next time we comeback down here."
United States
Todd U.
The price is £798
includes taxes & fees
18 Oct - 19 Oct
Villa Paradiso
A modern living room with a sofa, a small table, a baby playpen, and a wall-mounted TV.

14. Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!

Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!
Spring Valley
9.2 out of 10, Wonderful, (9 reviews)
"Location was perfect for our needs. Great space for the dogs too. "
United States
Hayley G.
The price is £298
includes taxes & fees
13 Oct - 14 Oct
Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!
A modern living room with a grey sofa, a small round coffee table, and a ceiling fan.

15. Charming 1-bedroom house in Beautiful San Diego with WiFi, AC

Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
Mid-City
10.0 out of 10, Exceptional, (2 reviews)
"Our stay was excellent. We enjoyed the space. Used TV, sofa and bed… nothing else. Quiet and easy access to property. "
United States
Socorro C.
The price is £234
includes taxes & fees
12 Oct - 13 Oct
Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
An outdoor patio with a table and chairs, string lights, and a grill.

16. 3 Bedroom House - Fire Pit Table, BBQ - 10 Guests

3 Bedroom House - Fire Pit Table, BBQ - 10 Guests
La Mesa
9.2 out of 10, Wonderful, (15 reviews)
"Adam was great! Communicated regularly and ensured I was good to go from the start. "
United States
Beth H.
The price is £375
includes taxes & fees
7 Oct - 8 Oct
3 Bedroom House - Fire Pit Table, BBQ - 10 Guests
A living room with a flat-screen TV on a wooden wall, a sofa, a coffee table with a tray, and a door leading to another room.

17. SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.

SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.
Mid-City
9.4 out of 10, Exceptional, (19 reviews)
"The location was great for getting to all the top attractions in San Diego. The back yard and garden was very peaceful and great for kids to explore!"
United States
Jenna T.
The price is £285
includes taxes & fees
27 Oct - 28 Oct
SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.
living room area

18. Bike to the Beach from Contemporary Studio Guesthouse

Bike to the Beach from Contemporary Studio Guesthouse
Pacific Beach
10.0 out of 10, Exceptional, (3 reviews)
"Great communication with the host throughout our stay. Rental was clean and in a very safe area. Beautiful ocean views from the park. Would stay here again."
United States
Kaleialoha S.
The price is £169
includes taxes & fees
12 Oct - 13 Oct
Bike to the Beach from Contemporary Studio Guesthouse
A dining area with a large table, blue chairs, and a view of palm trees and mountains.

19. Luxury Hilltop Estate I Resort Pool I Sunset Views

Luxury Hilltop Estate I Resort Pool I Sunset Views
Rancho San Diego
9.8 out of 10, Exceptional, (21 reviews)
"We had a fantastic time, highly recommend staying that this property! "
United States
Alex E.
The price is £925
includes taxes & fees
4 Oct - 5 Oct
Luxury Hilltop Estate I Resort Pool I Sunset Views
Living area

20. 2-bedroom townhome in marvelous San Die

2-bedroom townhome in marvelous San Die
Mid-City
9.2 out of 10, Wonderful, (9 reviews)
"This is my second time staying in this spot and it’s perfect! Everything went as planned and was a great, will definitely book again."
United States
SEBASTIAN V.
The price is £237
includes taxes & fees
13 Oct - 14 Oct
2-bedroom townhome in marvelous San Die
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"My favorite place to stay for a quick trip to San Diego. Very comfortable and clean rooms. The pool and hot tub add a special touch to your stay. Front desk customer service is superb. Very friendly and helpful. Breakfast is also delicious with hot coffee station."
JoHanna 2-night trip
Posted less than an hour ago
The Alcala Hotel Mission Valley/Seaworld

Find out more about Santee

Santee Holiday Homes information

Number of reviews
231
Accommodation
3680 Holiday Homes
Lowest Price
£158
Highest Price
£925