Santana Holidays from £625

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Your Santana Holiday

When a getaway to the city is calling, answer it with a holiday package to Santana. The neighbourhood of Barrio Pueblo, which is good for dining, families and fishing, makes an awesome base for your adventures. Church of Porta Coeli, Universidad Interamericana and Casa Morales are just a few of the sights worth exploring during your trip to Santana. Whatever your travel plans or the size of your budget, putting together a tailored Santana holiday is easy with Expedia.

Top Santana Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Villas De Playa 2
Signature Collection at Rio Mar
Hotel Puerto Valdes
Ocean Breeze Villa
Decanter Hotel

Santana Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Rafael Hernandez Airport (BQN)
Max Temp Winter
27ºC
Max Temp Summer
29ºC

Top hotels in Santana

Nature's Lodge Escape

Nature's Lodge Escape

Sabana Grande Sabana Grande
The price is £115 per night from 30 Jun to 1 Jul
£115
30 Jun - 1 Jul
includes taxes & fees
8.8/10 Excellent! (5 reviews)
"Clean and organized, love the mountain view."

Reviewed on 28 May 2026

Nature's Lodge Escape
Aquarius Vacation Club at Boqueron Beach Resort

Aquarius Vacation Club at Boqueron Beach Resort

3.5 out of 5
Carretera 101 Km 18.1 Cabo Rojo
The price is £139 per night from 21 Jun to 22 Jun
£139
21 Jun - 22 Jun
includes taxes & fees
9.2/10 Wonderful! (2,551 reviews)
"Excelente servicio muy buena localización acceso a la playa y el poblado boquerón"

Reviewed on 16 Jun 2026

Aquarius Vacation Club at Boqueron Beach Resort
Holiday Inn Mayaguez and Tropical Casino by IHG

Holiday Inn Mayaguez and Tropical Casino by IHG

3.5 out of 5
2701 Highway #2 Hostos Avenue Mayagüez
Fully refundable
The price is £126 per night from 24 Jun to 25 Jun
£126
24 Jun - 25 Jun
includes taxes & fees
9.4/10 Exceptional! (1,198 reviews)
"Room chair was stained lamp was broken but they replaced it"

Reviewed on 17 Jun 2026

Holiday Inn Mayaguez and Tropical Casino by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.