
Santa Rosa Holidays from £580
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to £335 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Packages with flights are ATOL protected
Top Santa Rosa Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.

Hotel Casa Panamá
Casco Viejo
Price was £808, price is now £580 per person
£580
per person
8 Nov - 15 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
7.4/10 Good! (562 reviews)
The hotel was average. The shower was never warm. It took some getting used to taking cold showers. But, otherwise it was in a very convenient location where you can walk to all attractions in Casco. There is a strong police presence so I always felt safe. Prices are expensive in this area.
Reviewed on 3 Aug 2025


Hotel Plaza Herrera
Casco Viejo
Price was £1,461, price is now £1,103 per person
£1,103
per person
8 Nov - 15 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
10/10 Exceptional! (9 reviews)
The property was beautiful done. The wood craft was amazing but most of all the staff and owner made it exceptional. I would highly recommend to anyone looking to stay in Panama city. Location is perfect as well!
Reviewed on 19 Aug 2025

Casa Mallet by Wynwood House
Casco Viejo
Price was £1,064, price is now £819 per person
£819
per person
8 Nov - 15 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
9.8/10 Exceptional! (21 reviews)
It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment.
Reviewed on 23 Jul 2025

Casa Contemporanea by Wynwood House
Casco Viejo
Price was £874, price is now £703 per person
£703
per person
8 Nov - 15 Nov
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very Good! (18 reviews)
Great experience, beautiful apartment. Minor maintenance issues that were addressed in a timely fashion. Would definitely recommend and stay there again!
Reviewed on 28 Mar 2025
Top hotels in Santa Rosa

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £82 per night from 30 Aug to 31 Aug
£82
30 Aug - 31 Aug
includes taxes & fees
9/10 Wonderful! (4,208 reviews)
"The location was amazing and hotel was amazing however I was very disappointed that the pool was closed for our entire trip."
Reviewed on 26 Aug 2025

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is £82 per night from 8 Sept to 9 Sept
£82
8 Sept - 9 Sept
includes taxes & fees
9/10 Wonderful! (441 reviews)
"Pool area was Amazing! The male bartender by the gym was OUTSTANDING!!"
Reviewed on 27 Aug 2025

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £109 per night from 12 Sept to 13 Sept
£109
12 Sept - 13 Sept
includes taxes & fees
8.4/10 Very Good! (936 reviews)
"Everyone was very nice and accommodating. The staff was primarily bilingual, offered to help with anything needed, and offered water bottles as part of the service."
Reviewed on 21 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.