Title: Hotels in Santa Rosa - Best Santa Rosa Hotels from £22 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Rosa](https://expedia.co.uk/Santa-Rosa-Holiday-Rentals.d829297946878021632.Travel-Guide-HolidayRentals)[Santa Rosa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Rosa.d829297946878021632.Car-Hire-Guide)[Santa Rosa Holidays](https://expedia.co.uk/Santa-Rosa.d829297946878021632.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Rosa Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&lodging=APARTMENT) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=OCEAN_VIEW) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-01-31&d1=2026-01-31&endDate=2026-02-02&d2=2026-02-02&lodging=CONDO) ## Check prices for these dates Tonight [17 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=829297946878021632&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [18 Jan - 19 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=829297946878021632&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=829297946878021632&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=829297946878021632&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Rosa hotels ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/f2fa3d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) Bella Vista 9.0/10 Wonderful (4,847 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Teresa £95 includes taxes & fees 18 Feb - 19 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/166e4001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (655 reviews) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £215 includes taxes & fees 6 Feb - 7 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Food and drink](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/c1dda5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/1cf4d9ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/f53158fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/afc6d0da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall [](https://www.expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) San Antonio 8.8/10 Excellent (1,004 reviews) "Room and staff were great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Akash £83 includes taxes & fees 6 Feb - 7 Feb [](https://www.expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/fe3d7092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/ae564df0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/7b45a441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador 8.6/10 Excellent (1,000 reviews) "Unbeatable location if your visit is all about the Panama Canal. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vitaliy £62 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/91ac7bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/05c7fc0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/3db8be94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/5b3a3c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Paitilla Inn Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) San Francisco 9.4/10 Exceptional (2,148 reviews) "Definitely a great place to stay. Staff was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £92 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/6fa9ba2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w2560h3836x0y4-b9b31746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/4edef1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) Bella Vista 9.8/10 Exceptional (171 reviews) "Very clean modern rooms, spacious hotel, delicious breakfast, very friendly staff!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sheldon £135 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/c826c327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/49d1f8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/94455d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Plaza by Wyndham Panama Punta Pacifica [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) San Francisco 9.6/10 Exceptional (1,145 reviews) "Great staff, breakfast and location " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Corinne £88 includes taxes & fees 3 Feb - 4 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (193 reviews) "Really loved this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandra £103 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/5b910cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/243f1471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 6:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Executive Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) Bella Vista 9.2/10 Wonderful (1,005 reviews) "A nice hotel to stay great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) angela £70 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/aee77a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/fd44364f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/9e0f8c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Principe Hotel and Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) Bella Vista 9.0/10 Wonderful (1,656 reviews) "Location, clean, good helpful staff" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Rocky £48 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (1,005 reviews) "Super friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Geoffrey £106 includes taxes & fees 23 Jan - 24 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/bfbd00a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/cd74829c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/e8a459e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Americas Golden Tower Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) San Francisco 9.0/10 Wonderful (1,002 reviews) "Great staff, great room, great time in Panama" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darius £96 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,004 reviews) "Great Hotel and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rudolph £229 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Daily buffet breakfast (PAB 10 per person)](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/b50bcacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/675171b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/7c4bef31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/14f91618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospedium Princess Hotel Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) Bella Vista 7.6/10 Good (740 reviews) "Very polite staff and great service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scot Da £42 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/a4c743af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/5668186f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/49b75ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/deeb0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Panama Centro Via Argentina [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) Bella Vista 7.4/10 Good (277 reviews) "Good room - clean and quiet, Hotel location is on a commercial street with many restaurants and bars nearby and within walking distance to a metro station. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) P £59 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34300000/34297500/34297431/48461ff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34300000/34297500/34297431/f7449602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/35000000/34300000/34297500/34297431/d4606e4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34300000/34297500/34297431/3a32abb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Milan [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Milan.h34297431.Hotel-Information) Bella Vista 9.0/10 Wonderful (446 reviews) "Great place for a short stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £33 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Milan.h34297431.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/2e6f2507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/5a0a24e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) Casco Viejo 9.4/10 Exceptional (268 reviews) "Clean, lovely staff and a fun area outside your door for drinks and food" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Angela £91 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/f6840e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Bella Vista 8.8/10 Excellent (1,000 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hugh £111 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![Presidential Studio Suite | Premium bedding, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/dddd2643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/4e16d91f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/958b7b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/54450a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Ojos del Rio [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) Calidonia 8.2/10 Very good (935 reviews) "Nice budget hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Turnell £37 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3b8e5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/96fd75ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/d27e0b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/6db7ada6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Urban Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) Bella Vista 8.8/10 Excellent (1,055 reviews) "good location most staff very friendly " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Ron £69 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=829297946878021632&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels) ## Top Santa Rosa Hotel Reviews ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg) ### Hyatt Regency Panama City 10/10 Excellent "The rooms had a great layout, very clean, very beautiful hotel. Love..love the breakfast options. Very safe location." [](https://expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "I really loved the service and friendliness of staff. Had 1 bad experience at Ibiza but Arturo made it better. I really loved the resort and will be returning." [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Courtyard by Marriott Panama Metromall](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/w3989h2656x0y8-13f5112b_y.jpg) ### Courtyard by Marriott Panama Metromall 10/10 Excellent "Food was great Everything was wonderful" [](https://expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "T" [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Nice comfortable hotel and very friendly staff." [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Execellent ad aiesys" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "All very good and great value! Great location too." [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Great staff in the location very helpful " [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "awesome location, great staff" [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ## More cheap stays in Santa Rosa ![La Cubana Hotel & Residencial](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/5cf5cc1f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Cubana Hotel & Residencial Calle 11 y Avenida Bolivar Colon Panama £28 1 Feb - 2 Feb includes taxes & fees 8.2/10 Very Good! (114 reviews) [](https://expedia.co.uk/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) ![Panama House Bed & Breakfast](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/0f765b96_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Panama House Bed & Breakfast Calle 1era El Carmen- Casa # 32 Panama City £34 21 Jan - 22 Jan includes taxes & fees 8.8/10 Excellent! (188 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Viajero Casco Viejo Hostel](https://images.trvl-media.com/lodging/119000000/118800000/118790900/118790803/2c436ca6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Viajero Casco Viejo Hostel Avenida B, Calle 12 Este, Casco Viejo Panama City £45 1 Feb - 2 Feb includes taxes & fees 7.2/10 Good! (13 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Viajero-Casco-Viejo-Hostel.h118790803.Hotel-Information) ![Magnolia Inn](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Magnolia Inn 8-18 Calle 8 y Calle Boquete Panama City Panama £62 21 Jan - 22 Jan includes taxes & fees 8.8/10 Excellent! (425 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province £103 20 Jan - 21 Jan includes taxes & fees 9.2/10 Wonderful! (191 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Hotel República](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel República Plaza 5 De Mayo Final Ave Panama City Panama [Get rates](https://expedia.co.uk/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=3257592&PinnedHotelID=3257592&HadPinnedHotel=true®ionId=829297946878021632) 6.4/10 (181 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa Rosa? > This central district is the heart of Santa Rosa, offering easy access to local amenities and a pleasant environment for visitors. You'll find a selection of boutique hotels and guesthouses here, often housed in charming historic-style buildings. The streets are generally well-maintained and offer a relaxed pace, great for exploring on foot. The square itself is a lovely spot for an evening stroll, often bustling with local life. > > > For couples looking for a relaxed yet engaging experience, staying near Parque Central is ideal. You'll be within walking distance of the town's best restaurants, artisanal shops, and cultural points of interest like the historic church. It's a great base for enjoying local cuisine and the town's character without needing to travel far. > > > Solo travellers will also appreciate the convenience and welcoming feel of this central area. It's easy to meet other travellers or locals in the cafes around the square, and having everything within a short walk makes exploring simple and stress-free. ### When is the best time to go to Santa Rosa? > During these months, you'll experience consistently sunny weather and lower humidity, making it ideal for exploring the region's natural beauty and outdoor activities. The calmer seas during this period are also superb for boat trips, snorkelling, or simply relaxing on the beaches. > > > For travellers looking to combine their visit with local festivities, late February or early March can be a good option as it often coincides with Carnival, a lively and colourful celebration across Panama. However, do be aware that accommodation might be more booked up and prices slightly higher during this peak time. > > > If your priority is to avoid the largest crowds and potentially find better value on flights and hotels, consider visiting in late November or early December, just as the dry season begins, or in late May, at the very start of the rainy season. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Rosa hotel booking with Expedia? ### How much is the nightly rate at a Santa Rosa hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [Buena Vista Hotels ](https://www.expedia.co.uk/Buena-Vista-Hotels.d829297953834291200.Travel-Guide-Hotels) - [Buenaventura Hotels ](https://www.expedia.co.uk/Buenaventura-Hotels.d3000409855.Travel-Guide-Hotels) - [Cativa Hotels ](https://www.expedia.co.uk/Cativa-Hotels.d553248623142874455.Travel-Guide-Hotels) - [Colon Hotels ](https://www.expedia.co.uk/Colon-Hotels.d601867.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Cristobal ](https://www.expedia.co.uk/Cristobal-Hotels-Gay-Friendly-Hotel.0-0-d6024083-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Colón Hotels ](https://www.expedia.co.uk/Destinations-In-Colon.d6246274.Hotel-Destinations) - [Escobal Hotels ](https://www.expedia.co.uk/Escobal-Hotels.d829297897546739712.Travel-Guide-Hotels) - [Fort Sherman Hotels ](https://www.expedia.co.uk/Fort-Sherman-Hotels.d6223313.Travel-Guide-Hotels) - [Gamboa Hotels ](https://www.expedia.co.uk/Gamboa-Hotels.d6025059.Travel-Guide-Hotels) - [Hotels near Gamboa Rainforest Resort ](https://www.expedia.co.uk/Gamboa-Rainforest-Resort-Hotels.0-l6078513-0.Travel-Guide-Filter-Hotels) - [Limón Hotels ](https://www.expedia.co.uk/Limon-Hotels.d829297944220938240.Travel-Guide-Hotels) - [Maria Chiquita Hotels ](https://www.expedia.co.uk/Maria-Chiquita-Hotels.d6344217.Travel-Guide-Hotels) - [Mechi Hotels ](https://www.expedia.co.uk/Mechi-Hotels.d6341639.Travel-Guide-Hotels) - [Portobelo Hotels ](https://www.expedia.co.uk/Portobelo-Hotels.d6145607.Travel-Guide-Hotels) - [Puerto Pilón Hotels ](https://www.expedia.co.uk/Puerto-Pilon-Hotels.d829297941343653888.Travel-Guide-Hotels) - [Rio Gatun Hotels ](https://www.expedia.co.uk/Rio-Gatun-Hotels.d3000404866.Travel-Guide-Hotels) - [Sabanitas Hotels ](https://www.expedia.co.uk/Sabanitas-Hotels.d3000437347.Travel-Guide-Hotels) - [Salamanca Hotels ](https://www.expedia.co.uk/Salamanca-Hotels.d829297957902774272.Travel-Guide-Hotels) - [Flights to Colon ](https://www.expedia.co.uk/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights) - [Flights to Enrique Adolfo Jimenez ](https://www.expedia.co.uk/Cheap-Flights-To-Enrique-Adolfo-Jimenez.d3000676041.Travel-Guide-Flights) - [Flights to Gamboa ](https://www.expedia.co.uk/Cheap-Flights-To-Gamboa.d6025059.Travel-Guide-Flights) - [Flights to Portobelo ](https://www.expedia.co.uk/Cheap-Flights-To-Portobelo.d6145607.Travel-Guide-Flights) - [Flights from Enrique Adolfo Jimenez ](https://www.expedia.co.uk/lp/airports/onx/flights-from-enrique-adolfo-jimenez-airport) - [Flights from Miami (MIA) to Colon (ONX) ](https://www.expedia.co.uk/lp/flights/mia/onx/miami-to-colon) - [Flights from Milan (MIL) to Colon (ONX) ](https://www.expedia.co.uk/lp/flights/mil/onx/milan-to-colon) - [Visit Cativa ](https://www.expedia.co.uk/Cativa.dx553248623142874455) - [Visit Coco Solo ](https://www.expedia.co.uk/Colon-Coco-Solo.dx553248635974899440) - [Colon Free Zone ](https://www.expedia.co.uk/Colon-Free-Zone-Barrio-Sur.d6078503.Attraction) - [Colon Holidays ](https://www.expedia.co.uk/Colon.d601867.Holidays-City-Breaks) - [Cristobal Holidays ](https://www.expedia.co.uk/Cristobal.d6024083.Holidays-City-Breaks) - [Visit Cristobal ](https://www.expedia.co.uk/Cristobal.dx6024083) - [Gamboa Rainforest Resort ](https://www.expedia.co.uk/Gamboa-Rainforest-Resort-Colon.d6078513.Attraction) - [Gamboa Holidays ](https://www.expedia.co.uk/Gamboa.d6025059.Holidays-City-Breaks) - [Limon Bay ](https://www.expedia.co.uk/Limon-Bay-Colon.d6035251.Attraction) - [Car hire Colon ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Colon.d601867.Car-Hire-Guide) - [Car hire near Colón ](https://www.expedia.co.uk/Destinations-In-Colon.d6246274.Car-Hire-Destinations) - [Dirent Rental Cars in Mechi ](https://www.expedia.co.uk/Dirent-Car-Rentals-In-Mechi.d6341639-c1110.Car-Rental-Guide-Suppliers) - [Buenaventura Holiday Rentals ](https://www.expedia.co.uk/Buenaventura-Holiday-Rentals.d3000409855.Travel-Guide-HolidayRentals) - [Things to do in Colon ](https://www.expedia.co.uk/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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