Santa María Holidays from £1,313

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £250 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your Santa María Holiday

With plenty of highlights as well as some hidden gems, this city is best explored with a Santa María holiday package. Find a place to stay in El Arenal, which is good for walking, watersports and coastal beaches. If some sightseeing is on the agenda during your trip to Santa María, swing by leading attractions such as General Villamil Beach. No matter your travel plans or budget, putting together the ultimate tailored Santa María holiday is a cinch with Expedia.

Top Santa María Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Presidente Internacional
Hotel Río Guayas by Art Hotels Ecuador
Luxury Suites Riverfront GYE
Hotel Marcelius
Radisson Hotel Guayaquil

Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Max Temp Winter
24ºC
Max Temp Summer
24ºC

Top hotels in Santa María

Hotel La Ría Playas

Hotel La Ría Playas

3 out of 5
Km 1.5 Vía a Data Playas Guayas
The price is £43 per night from 3 May to 4 May
£43
3 May - 4 May
Hotel La Ría Playas
Karibao Resort Town

Karibao Resort Town

4 out of 5
Km 7.5 Via a Playas Engabao Playas Guayas
Fully refundableReserve now, pay when you stay
The price is £132 per night from 4 May to 5 May
£132
4 May - 5 May
9/10 Wonderful! (17 reviews)
Construction area

Reviewed on 2 Apr 2026

Karibao Resort Town
Hotel Presidente Beach Playas

Hotel Presidente Beach Playas

3 out of 5
C. 1 Playas Guayas
Fully refundableReserve now, pay when you stay
The price is £72 per night from 19 May to 20 May
£72
19 May - 20 May
8.8/10 Excellent! (38 reviews)
The place was clean, the services of the staff were excellent, great breakfast and clean & warm pool. I had very good time

Reviewed on 28 Mar 2026

Hotel Presidente Beach Playas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.