Santa Maria Holidays from £280

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Santa Maria Holiday

Come and experience this captivating city for yourself with a Santa Maria holiday package. Think about staying in the neighbourhood of Marciano della Chiana, which is good for views and nature, and your time here is sure to be unforgettable. Church of S. Francesco is just one of the famous attractions to add to your itinerary during a trip to Santa Maria. Check out Expedia's extensive range of travel options and start planning your perfect holiday to Santa Maria now.

Top Santa Maria Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Via Del Santo

Via Del Santo

1 out of 5
Save 100% on your flight
Price was £496, price is now £280 per person
£280
per person
6 Sept - 9 Sept
found 1 day ago
Return flight included
London (LON) to Pisa (PSA)
8.8/10 Excellent! (45 reviews)
Excellent location. Great property

Reviewed on 18 Jul 2026

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Price was £1,137, price is now £534 per person
£534
per person
14 Oct - 19 Oct
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
7.6/10 Good! (1,004 reviews)
The room was clean and air conditioning worked well for the size of room. However, the room was a little small for a family of four. The location was one of the best aspects of the hotel: it was right in the historic centre and near all the attractions. Staff were also very helpful, promptly responding to our requests.

Reviewed on 2 Aug 2026

Villa Cora

Villa Cora

5 out of 5
Oltrarno
Price was £3,174, price is now £1,746 per person
£1,746
per person
14 Sept - 19 Sept
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
9.8/10 Exceptional! (479 reviews)

Precise Tale Poggio Alla Sala

Precise Tale Poggio Alla Sala

5 out of 5
Price was £3,963, price is now £2,229 per person
£2,229
per person
22 Sept - 29 Sept
found 1 day ago
Return flight included
London (LGW) to Florence (FLR)
9.6/10 Exceptional! (154 reviews)
The place it’s an Amazing. Very clean. Is more beautiful than the pictures.

Reviewed on 2 Aug 2026

Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £489, price is now £289 per person
£289
per person
4 Oct - 6 Oct
found 1 day ago
Return flight included
London (LGW) to Florence (FLR)
7.4/10 Good! (1,011 reviews)

Santa Maria Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Max Temp Winter
7ºC
Max Temp Summer
27ºC

Top hotels in Santa Maria

Precise Tale Poggio Alla Sala

Precise Tale Poggio Alla Sala

5 out of 5
Via Poggio alla Sala 10 Montepulciano SI
Fully refundableReserve now, pay when you stay
The price is £455 per night from 17 Aug to 18 Aug
£455
17 Aug - 18 Aug
includes taxes & fees
9.6/10 Exceptional! (156 reviews)
"The place it’s an Amazing. Very clean. Is more beautiful than the pictures."

Reviewed on 2 Aug 2026

Precise Tale Poggio Alla Sala
Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6 Cortona AR
The price is £528 per night from 18 Aug to 19 Aug
£528
18 Aug - 19 Aug
includes taxes & fees
9.8/10 Exceptional! (241 reviews)
"Very clean and very quiet"

Reviewed on 15 Jul 2026

Villa di Piazzano - Small Luxury Hotel of the World
Monastero di Cortona Hotel & Spa

Monastero di Cortona Hotel & Spa

5 out of 5
Via del Salvatore Cortona AR
Fully refundableReserve now, pay when you stay
The price is £270 per night from 18 Aug to 19 Aug
£270
18 Aug - 19 Aug
includes taxes & fees
10/10 Exceptional! (302 reviews)
"Unbelievable hotel. Staff were so fantastic and nice. 10/10 stay!"

Reviewed on 2 Aug 2026

Monastero di Cortona Hotel & Spa
See all 5,188 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Maria

Wine & Music on the Terrace

Wine & Music on the Terrace

£17
per adult
Wine & Music on the Terrace
Oil museum and oil mill in Tuscany: tour and tasting

Oil museum and oil mill in Tuscany: tour and tasting

£17
per adult
Oil museum and oil mill in Tuscany: tour and tasting
Arezzo: Val di Chiana Wine Tasting Experience

Arezzo: Val di Chiana Wine Tasting Experience

£34
per adult
Arezzo: Val di Chiana Wine Tasting Experience
See all activities in Santa Maria

Frequently asked questions

How much does a Santa Maria travel package cost?
Our Santa Maria travel packages, which start at just £280, are an ideal way to save big bucks. All you have to do is choose your favourite hotels, flights and rental car to create your dream getaway.
If I'm not able to travel, can I cancel my Santa Maria travel package?
Whether it's your hotel or flight, you can cancel or alter it. Booked your Santa Maria travel package in the last 24 hours? You may be able to make changes for free. If it's been longer than that, you may be charged a fee by your hotel, airline or car rental company. For further information, head to our Customer Service Portal. We'll help you each step of the way.
How do I get a cheap travel package to Santa Maria?
Our Santa Maria holiday packages promise plenty of savings for the savvy explorer. For the best deals, simply combine your flights, hotels and extras (including activities) into a convenient package. But cheap prices are just the beginning of your next unforgettable adventure. When you book with Expedia, you'll have more than 550 airlines and 1,000,000 hotel options throughout the world to pick from. No matter your budget, there's a holiday package here just for you.
Does Expedia offer Book Now, Pay Later Santa Maria holidays?
Expedia has joined forces with online lender Klarna to make your next getaway easier on the purse strings. Paying by instalment means you can spread the costs of your next big holiday, leaving you with more money to spend while you're away. Klarna has several payment plans to choose from, so you're sure to find something that falls within your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your holiday over multiple transactions.
  • Low deposit holidays: Clicking on the "book now" button is much easier with this payment plan. Simply put down a small deposit on your booking and then start packing your bags.

Where should I stay in Santa Maria?
We recommend staying near the action. Many people like to book hotels around popular attractions, like Church of S. Francesco, Piazza del Tribunal and Museum of Lucignano.
What are the top hotels in Santa Maria?
B&B Il Gianduia and Casa Clementina are two of the most popular hotels in Santa Maria. Why not take a look at the amenities and rates at each and then make a decision?
How far in advance should I book my Santa Maria holiday?
Browse Expedia to compare international airfares as soon as you've got your travel dates. In many cases, you can purchase a seat up to 12 months before departure. If it's too early for your preferred carrier, or you're booking late, don't stress. The lowest prices to Santa Maria occasionally appear a few weeks before the date of departure.
What does an Expedia Santa Maria travel package include?
Flights, car rentals and hotels — we bring you the best deals. All you'll have to do is select your ideal combination. Once you've made your booking, you can add on the fun stuff like experiences and tours. Our travel packages make it simple to craft an amazing Santa Maria holiday.
What should I know before booking a Santa Maria travel package?
When you book your flights, hotels and car rentals together, you'll enjoy incredible discounts. Whether you're planning a wilderness getaway in a cabin or would rather stay in a convenient hotel in the city, Expedia will make it happen for less.
Can I choose my airline with a Santa Maria Expedia travel package?
Yes — that's one of the best things about an Expedia travel package. You're in control. We have access to more than 550 partner airlines across the globe, so you have lots of choice when arranging your Santa Maria escape.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.