Santa Maria Holidays from £224

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Your Santa Maria Holiday

Come and experience this captivating city for yourself with a Santa Maria holiday package. Think about staying in the neighbourhood of Marciano della Chiana, which is good for views and nature, and your time here is sure to be unforgettable. Church of S. Francesco is just one of the famous attractions to add to your itinerary during a trip to Santa Maria. Check out Expedia's extensive range of travel options and start planning your perfect holiday to Santa Maria now.

Top Santa Maria Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Villa Liana

Hotel Villa Liana

3 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £359, price is now £224 per person
£224
per person
30 Dec - 1 Jan
just found
Return flight included
Birmingham (BHX) to Florence (FLR)
8.8/10 Excellent! (373 reviews)

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Price was £1,046, price is now £547 per person
£547
per person
29 Dec - 2 Jan
found 3 hours ago
Return flight included
London (LGW) to Florence (FLR)
7.6/10 Good! (1,003 reviews)
Perfect location

Reviewed on 2 Nov 2026

Alfieri9

Alfieri9

3 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £376, price is now £231 per person
£231
per person
30 Dec - 1 Jan
just found
Return flight included
Birmingham (BHX) to Florence (FLR)
9.6/10 Exceptional! (175 reviews)

Villa Tolomei Hotel & Resort

Villa Tolomei Hotel & Resort

5 out of 5
Oltrarno
Save 100% on your flight
Price was £1,021, price is now £647 per person
£647
per person
13 Jan - 20 Jan
found 20 hours ago
Return flight included
London (LHR) to Florence (FLR)
8.8/10 Excellent! (445 reviews)

The Hoxton, Florence

The Hoxton, Florence

4 out of 5
Historic Centre of Florence
Price was £636, price is now £408 per person
£408
per person
13 Dec - 20 Dec
found 1 day ago
Return flight included
Birmingham (BHX) to Florence (FLR)
9.4/10 Exceptional! (370 reviews)

Santa Maria Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Max Temp Winter
7ºC
Max Temp Summer
27ºC

Top hotels in Santa Maria

Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6 Cortona AR
Get rates
Villa di Piazzano - Small Luxury Hotel of the World
Precise Tale Poggio Alla Sala

Precise Tale Poggio Alla Sala

5 out of 5
Via Di Poggio Alla Sala, 10 Montepulciano SI
Get rates
Precise Tale Poggio Alla Sala
Nuovo Etruria Resort

Nuovo Etruria Resort

4 out of 5
Via di S. Martino snc Montepulciano SI
The price is £84 per night from 13 Nov to 14 Nov
£84
13 Nov - 14 Nov
includes taxes & fees
Nuovo Etruria Resort
See all 5,063 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Maria

Montepulciano Wine Tasting in the Tuscan Countryside

Montepulciano Wine Tasting in the Tuscan Countryside

£21
per adult
Montepulciano Wine Tasting in the Tuscan Countryside
Farming experience with an extra virgin olive oil producer in Arezzo

Farming experience with an extra virgin olive oil producer in Arezzo

£55
per adult
Farming experience with an extra virgin olive oil producer in Arezzo
Montepulciano: Wine Tour and tasting

Montepulciano: Wine Tour and tasting

£44
per traveller
Montepulciano: Wine Tour and tasting
See all activities in Santa Maria

Frequently asked questions

How much does a Santa Maria travel package cost?
Our Santa Maria travel packages, which start at just £224, are an ideal way to save big bucks. All you have to do is choose your favourite hotels, flights and rental car to create your dream getaway.
If I'm not able to travel, can I cancel my Santa Maria travel package?
Whether it's your hotel or flight, you can cancel or alter it. Booked your Santa Maria travel package in the last 24 hours? You may be able to make changes for free. If it's been longer than that, you may be charged a fee by your hotel, airline or car rental company. For further information, head to our Customer Service Portal. We'll help you each step of the way.
How do I get a cheap travel package to Santa Maria?
Our Santa Maria holiday packages promise plenty of savings for the savvy explorer. For the best deals, simply combine your flights, hotels and extras (including activities) into a convenient package. But cheap prices are just the beginning of your next unforgettable adventure. When you book with Expedia, you'll have more than 550 airlines and 1,000,000 hotel options throughout the world to pick from. No matter your budget, there's a holiday package here just for you.
Does Expedia offer Book Now, Pay Later Santa Maria holidays?
Expedia has joined forces with online lender Klarna to make your next getaway easier on the purse strings. Paying by instalment means you can spread the costs of your next big holiday, leaving you with more money to spend while you're away. Klarna has several payment plans to choose from, so you're sure to find something that falls within your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your holiday over multiple transactions.
  • Low deposit holidays: Clicking on the "book now" button is much easier with this payment plan. Simply put down a small deposit on your booking and then start packing your bags.

Where should I stay in Santa Maria?
We recommend staying near the action. Many people like to book hotels around popular attractions, like Church of S. Francesco, Piazza del Tribunal and Museum of Lucignano.
What are the top hotels in Santa Maria?
B&B Il Gianduia and Casa Clementina are two of the most popular hotels in Santa Maria. Why not take a look at the amenities and rates at each and then make a decision?
How far in advance should I book my Santa Maria holiday?
Browse Expedia to compare international airfares as soon as you've got your travel dates. In many cases, you can purchase a seat up to 12 months before departure. If it's too early for your preferred carrier, or you're booking late, don't stress. The lowest prices to Santa Maria occasionally appear a few weeks before the date of departure.
What does an Expedia Santa Maria travel package include?
Flights, car rentals and hotels — we bring you the best deals. All you'll have to do is select your ideal combination. Once you've made your booking, you can add on the fun stuff like experiences and tours. Our travel packages make it simple to craft an amazing Santa Maria holiday.
What should I know before booking a Santa Maria travel package?
When you book your flights, hotels and car rentals together, you'll enjoy incredible discounts. Whether you're planning a wilderness getaway in a cabin or would rather stay in a convenient hotel in the city, Expedia will make it happen for less.
Can I choose my airline with a Santa Maria Expedia travel package?
Yes — that's one of the best things about an Expedia travel package. You're in control. We have access to more than 550 partner airlines across the globe, so you have lots of choice when arranging your Santa Maria escape.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.