The Best Hotels in Santa Maria, Guayaquil - 2026 Updated Prices

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Where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

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Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

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Vista panorámica de las favelas de cerro santa ana, guayaquil, ecuador

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

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Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

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Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or World Trade Center.

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Top Santa Maria Hotel Reviews

Courtyard by Marriott Guayaquil

10/10 Excellent

"The staff members were respectful and assured that my stay met my expectation. Highly recommended."

Oro Verde Guayaquil

4/10 Poor

"This was not our best experience after numerous stays this was pretty much the worst. The room had a very strong musky smell that required deodorization, we were without hot water most of the time. In fairness, they wanted to move us to another room but after a long trip we had no energy to move again. The staff is always great and accommodating , yet the last few stays have disappointed us somewhat. Rooms are starting to show some real wear and tear, repairs would be appreciated."

DC Suites Aeropuerto

8/10 Good

"Very good location for arriving to or departing from the airport or bus terminal. You could technically walk to the airport, but if you’re carrying large luggage or arriving during the hotter parts of the day — which is common in Guayaquil — the walk can be difficult. The units have been nicely remodeled with modern finishes, especially the bathroom and room details. The area felt safe and quiet. One thing to keep in mind is that there is no elevator, and there are two large sets of stairs, which can be challenging with heavy luggage. The entrance is also a bit tricky to find at first since it is tucked inside an alley. Overall, a good stay for a quick stop in or out of Guayaquil. "

Unipark by Oro Verde Hotels

10/10 Excellent

"The room was clean and the view from the seventh floor was amazing facing the park and the cathedral. The buffet breakfast was hearty and with a good variety of local and general cuisine. The staff was very helpful and courteous. It was easy to reserve taxis directly from the hotel and the airport shuttle was large and air conditioned. It is walkable to the boardwalk and many other site seeing places in this historic section of the city. I would definitely book again if i return to this area of Guayaquil and highly recommend to others."

Frequently asked questions

When is the best time to go to Santa Maria?

The best time to visit Santa Maria is during the dry season, which runs from May to December, offering pleasant weather for exploring.

During these months, you'll experience less humidity and more sunshine, making it ideal for enjoying outdoor activities and sightseeing. The temperatures are consistently warm but not overly hot, typically ranging from 25°C to 30°C. This period is great for travellers who prefer clear skies and comfortable conditions for their adventures.

For those interested in wildlife, particularly birdwatching, the dry season is especially rewarding as many species are more active and visible.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Maria.

How can I save on a Santa Maria hotel booking with Expedia?

Members always get our best prices. Find our best Santa Maria hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

How much is the nightly rate at a Santa Maria hotel?

Hotel prices in Santa Maria often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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Our top choices for Santa Maria hotels

Holiday Inn Guayaquil Airport by IHG

Iguanazu Bed & Breakfast

DC Suites Aeropuerto

Oro Verde Guayaquil

Hilton Colon Guayaquil

Doubletree By Hilton Guayaquil

Hotel Puerto Pacifico Guayaquil Airport

Harmonie

Sheraton Guayaquil Hotel

Casa Serena

Courtyard by Marriott Guayaquil

Wyndham Guayaquil Puerto Santa Ana

Wyndham Garden Guayaquil

Unipark by Oro Verde Hotels

Hostal Macaw

NP Hotel & Suites

Grand Hotel Guayaquil, an Ascend Collection Hotel

MundialCity Hotel Guayaquil

Tropical Inn

NCG Suite 5

Where to stay in Santa Maria

Ecuador

Downtown Guayaquil

Puerto Santa Ana

Kennedy

Urdesa

Top Santa Maria Hotel Reviews

Courtyard by Marriott Guayaquil

Frequently asked questions