Santa Maria Holidays

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Your Santa Maria Holiday

Discover all the amazing things this neighbourhood has to offer with a customized Santa Maria holiday package. However you imagine yourself spending your days here, you'll find endless opportunities for adventure, relaxation and fun. Start your trip to Santa Maria with a visit to nearby attractions such as Banco Pichincha Monumental Stadium, Mall del Sol Commercial Centre and City Mall. Expedia can put your travel plans into action. Book your ultimate Santa Maria holiday now.

Price found within the past 48 hours. Click for updated prices.
  • Executive Suite | Premium bedding, minibar, in-room safe, desk
    Jul 27 - Aug 14

    Hotel Air Suites + Flight

    Simón Bolívar
    18 nights
    2.5 star property
    7.0/10 - Good (224 reviews)
    "Very helpful staff"
    Reviewed April 28, 2026
    Return • London (LHR) - Guayaquil (GYE)
    LHR - GYE • 2 stops GYE - LHR • 2 stops
    £1,760
    £1,541
    per traveller
    found 7 hours ago
    Hotel Air Suites
  • Lobby
    Jul 27 - Aug 14

    Hilton Colon Guayaquil + Flight

    Kennedy
    18 nights
    4.5 star property
    8.6/10 - Excellent (912 reviews)
    "It was perfect the staff was bilingual...came for my niece's 13th birthday....it was unbelievable."
    Reviewed May 17, 2026
    Return • London (LHR) - Guayaquil (GYE)
    LHR - GYE • 2 stops GYE - LHR • 2 stops
    £2,351
    £2,063
    per traveller
    found 7 hours ago
    Hilton Colon Guayaquil
  • Terrace/patio
    Jul 27 - Aug 14

    Hotel Marcelius + Flight

    Kennedy
    18 nights
    3.5 star property
    8.2/10 - Very good (239 reviews)
    "Very nice!"
    Reviewed April 28, 2026
    Return • London (LHR) - Guayaquil (GYE)
    LHR - GYE • 2 stops GYE - LHR • 2 stops
    £1,792
    £1,585
    per traveller
    found 7 hours ago
    Hotel Marcelius
  • Lobby
    Jul 27 - Aug 14

    Doubletree By Hilton Guayaquil + Flight

    Downtown Guayaquil
    18 nights
    5.0 star property
    9.0/10 - Wonderful (92 reviews)
    "The river view is spectacular"
    Reviewed May 18, 2026
    Return • London (LHR) - Guayaquil (GYE)
    LHR - GYE • 2 stops GYE - LHR • 2 stops
    £2,025
    £1,804
    per traveller
    found 7 hours ago
    Doubletree By Hilton Guayaquil
  • Rooftop terrace
    Jul 27 - Aug 14

    River View suites Puerto Santa Ana gye + Flight

    Puerto Santa Ana
    18 nights
    3.0 star property
    8.8/10 - Excellent (53 reviews)
    "Beautiful apartment suite very safe close ally restaurant next a 24 pharmacy ac worked perfectly fine pool was beautiful and refreshing "
    Reviewed April 23, 2026
    Return • London (LHR) - Guayaquil (GYE)
    LHR - GYE • 2 stops GYE - LHR • 2 stops
    £1,860
    £1,668
    per traveller
    found 7 hours ago
    River View suites Puerto Santa Ana gye

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador

Top hotels in Santa Maria

Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is £63 per night from 31 May to 1 Jun
£63
31 May - 1 Jun
9.6/10 Exceptional! (1,003 reviews)
"This was not our best experience after numerous stays this was pretty much the worst. The room had a very strong musky smell that required deodorization, we were without hot water most of the time. In fairness, they wanted to move us to another room but after a long trip we had no energy to move ..."

Reviewed on 20 May 2026

Oro Verde Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
The price is £81 per night from 31 May to 1 Jun
£81
31 May - 1 Jun
9.4/10 Exceptional! (1,007 reviews)
"yes"

Reviewed on 20 May 2026

Holiday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is £96 per night from 22 May to 23 May
£96
22 May - 23 May
9.2/10 Wonderful! (1,003 reviews)
"After staying here several times, the food and service are great!"

Reviewed on 14 May 2026

Wyndham Guayaquil Puerto Santa Ana
See all 449 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Maria travel package cost?
Maybe less than you imagined — from a tempting , actually! By bundling hotels, flights and car rentals into your own customized package, your getaway to Santa Maria is only clicks away.
If I'm not able to travel, can I cancel my Santa Maria travel package?
Yes, it's possible to cancel your Santa Maria booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your hotel, airline or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Head to our Customer Service Portal to find out more.
How do I get a cheap travel package to Santa Maria?
Crafting your own Santa Maria travel package with Expedia is such a simple way to save. We have access to more than 550 airlines and 1,000,000 hotel options worldwide. With such a fantastic range to choose from, you'll have no hassles putting together your dream getaway.
Does Expedia offer Book Now, Pay Later Santa Maria holidays?
Your bank balance shouldn't prevent you from escaping on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a terrific getaway without draining your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your break. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's manageable monthly instalment plans. If paying a little each month sounds right for you, choose this option during the checkout process.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your trip across multiple transactions.
  • Low deposit holidays: When you spot an unbeatable deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you lock it in.

Where should I stay in Santa Maria?
A journey to Santa Maria isn't complete without seeing Malecon 2000 and Banco Pichincha Monumental Stadium. Book somewhere close by for quick access to these popular attractions.
What are the top hotels in Santa Maria?
Book a room at Wyndham Guayaquil, Puerto Santa Ana. It's one of this area's most sought-after properties. Another reputable option in Santa Maria is Oro Verde Guayaquil.
How far in advance should I book my Santa Maria holiday?
It's difficult to pick the ideal time for airfares, but we generally say the earlier, the better. Most international journeys on Expedia become available to compare up to a year in advance. If you can't book early, don't stress. Discounted prices appear from time to time just weeks before departure dates.
What does an Expedia Santa Maria travel package include?
It comes down to what you want. If you're travelling alone, you might decide to combine flights and hotels. Taking the entire family to Santa Maria? A travel package including hotels, rental cars and flights might be a better fit. Expedia gives you the flexibility to build your own travel package.
What should I know before booking a Santa Maria travel package?
You'll pick up excellent savings when you combine your flights, hotels and rental cars into a travel package. Not only that, booking everything together simply makes planning easier. So why waste your time or money? Whether you're organising a luxury city stay with your love or a budget solo adventure, take a look at our package deals today.
Can I choose my airline with a Santa Maria Expedia travel package?
Definitely. Expedia has more than 550 airline partners to choose from all over the world. With such a huge range of choice, finding the ideal carrier to whisk you off to Santa Maria will be a cinch.

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

£87
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

£47
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Stop at willow fruit market 9 - Guayaquil

City Tour Guayaquil - For Seniors

£110
per adult
City Tour Guayaquil - For Seniors
See all activities in Guayaquil

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.