Santa Luca Holidays from £263

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Your Santa Luca Holiday

Planning your next adventure is a cinch with a Santa Luca holiday package. The neighbourhood of Castel Santa Maria, which is great for views, makes a superb base to uncover the delights of this city. A trip to Santa Luca is a great opportunity to do a bit of sightseeing. Check out well-known attractions like Borgia Castle, Ducal Palace of Camerino and Basilica of San Venancio. Expedia will help you escape the everyday. Tailor your holiday to Santa Luca to suit your style of travel, whatever that may be!

Top Santa Luca Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
View Place & Spa

View Place & Spa

£263
per person
13 Nov - 15 Nov
found 1 hour ago
Return direct flight included
London (LCY) to Ancona (AOI)
9.6/10 Exceptional! (55 reviews)
Villa Lattanzi

Villa Lattanzi

£503
per person
28 Oct - 31 Oct
found 13 hours ago
Return flight included
London (LGW) to Ancona (AOI)
9.4/10 Exceptional! (35 reviews)
Beautiful property in the perfect setting overlooking the Adriatic

Reviewed on 12 Aug 2026

Grand Hotel Palace

Grand Hotel Palace

Port Area
£327
per person
18 Nov - 22 Nov
found 18 hours ago
Return flight included
Manchester (MAN) to Ancona (AOI)
9.6/10 Exceptional! (387 reviews)
Great hotel and nice city

Reviewed on 17 Sept 2026

Mariani

Mariani

£334
per person
24 Oct - 27 Oct
found 4 hours ago
Return direct flight included
Manchester (MAN) to Ancona (AOI)
7.8/10 Good! (45 reviews)
The Mariani is a town centre business style hotel, perfectly located for the amenities of Jesi. Perfectly ok for what we needed. Good position for a town walk, restaurants and the Cio&Pio Gelato shop over the road which is highly recommended.

Reviewed on 27 Apr 2024

Santa Luca Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Max Temp Winter
7ºC
Max Temp Summer
27ºC
Top Sights
Borgia Castle, Ducal Palace of Camerino and Museum of Science

Top hotels in Santa Luca

Villa Miliani

Villa Miliani

Viale XXIV Maggio Fabriano AN
Fully refundableReserve now, pay when you stay
£67
11 Oct - 12 Oct
includes taxes & fees
10/10 Exceptional! (12 reviews)
"Very clean, friendly staff"

Reviewed on 27 Aug 2026

Villa Miliani
Borgo Lanciano Resort & Spa

Borgo Lanciano Resort & Spa

Loc Lanciano 5 Castelraimondo MC
£111
27 Sept - 28 Sept
includes taxes & fees
9.2/10 Wonderful! (52 reviews)
Quiet retreat!
"Could NOT get room cooler. Adjusted AC on thermostat and also turned unit to lowest setting, but we roasted. Couldn’t open Windows because no screens against mosquitoes. Other than that, it was clean and spacious. Restaurant was quite nice for dinner, and breakfast buffet was generous and of good ..."

Reviewed on 8 Oct 2021

Borgo Lanciano Resort & Spa
Beautifully restored villa with stunning views with yoga studio and private pool

Beautifully restored villa with stunning views with yoga studio and private pool

San Severino Marche
Beautifully restored villa with stunning views with yoga studio and private pool
See all 491 properties in Santa Luca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Why should I book my Santa Luca holiday with Expedia?
Choose Expedia to arrange your next adventure with ease, all in one convenient place. Our top tip for landing a fabulous deal on a Santa Luca retreat? Bundle your hotel, flights and/or hire car into a package holiday. Then throw in some fun tours and activities. Most bookings also include flexible cancellation policies, so there's no need to stress if you have to change your travel plans. Round-the-clock help with amending and cancelling your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in Santa Luca?
Peak season falls in May, August and September and is an exciting time to visit — if you don't mind the crowds. November, December and January are usually quieter times of the year. Plan your visit to Santa Luca according to what style of adventure you want. January is the coolest month, when daytime temperatures average 3ºC. In July, the warmest month, expect averages of 23ºC during the day.
What is the top hotel for my holiday in Santa Luca?
Put your feet up and relax in comfort in Santa Luca by choosing Borgo Dé Varano as your home base and gateway to adventure and exploration.
How do I get a cheap holiday to Santa Luca?
Booking a Santa Luca holiday with Expedia is the easiest way to save. We have over 400 air carriers and 321,000 hotel options around the globe. With such a wonderful range to select from, you'll have no issues putting together your ideal trip. Learn more about how you can save money on your holiday when you combine your flight and hotel bookings with Expedia.
What should I do on my Santa Luca holiday?
Ensure your holiday in Santa Luca is a memorable one by taking in its top attractions. Borgia Castle, Cavour Square, Rocca dAjello and Ducal Palace of Camerino are just a few of the things you must see while you're in the city.
Do I need a visa for my Santa Luca holiday?
Visa requirements for Santa Luca vary based on your nationality and the reason for your visit. It's wise to check official government websites to determine if you need a visa for your trip. This is also a good place to find the most up-to-date information, including details about application procedures and any supporting documentation you may need. Enquire about your visa requirements in advance to ensure a smooth travel experience. Also double-check to see that your passport has a minimum of six months validity from your planned date of return.
What should I wear on my Santa Luca holiday?
Though everyone's style differs, it can be useful to have a few guidelines for what kind of clothes to wear during your holiday in Santa Luca. Think about looking up social media before you leave to get inspiration for local fashion trends. Be sure to check the weather forecast so you can pack your bags accordingly. The warmest month in Santa Luca is July, with average daytime temperatures of 23ºC. If you plan to visit during the coolest month of January, the mercury hovers around 3ºC during the day.
What does an Expedia Santa Luca holiday include?
It depends on what sort of getaway you're thinking about. Santa Luca holiday deals can include flights, car hires and hotels. You can mix and match to find the travel package that fits your needs. You can also add on experiences and activities after you've booked to pick up even bigger discounts. Design your holiday just the way you want it with Expedia's flexible options.
Does Expedia offer Book Now, Pay Later Santa Luca holidays?
We sure do. Expedia has teamed up with online lender Klarna to help you conveniently pay for your holiday in instalments. Simply pick the payment plan that works for you during the checkout process and take the stress out of budgeting for your next trip. Make sure you bundle your flights, accommodation and activities with Expedia to get the biggest bang for your travel buck. Take a look at our flexible payment options below:
  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's convenient monthly instalment plans. If paying across multiple instalments works for you, choose this option at checkout.
  • No-deposit holidays: If not paying upfront for your getaway makes hitting that "book now" button more stress-free, opt for a no-deposit holiday plan from Klarna so you can Book Now, Pay Later!
Can I choose my airline with a Santa Luca Expedia holiday?
Yes — and it's easy too. Expedia has access to more than 400 partner airlines globally. Our packages give you the freedom to pick from available flights, hotels and activities that suit you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.