Title: Holiday Rentals Santa Isabel from £75: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk

[Hotels in Santa Isabel](https://expedia.co.uk/Santa-Isabel-Hotels.d6035096.Travel-Guide-Hotels)[Flights to Santa Isabel](https://expedia.co.uk/Cheap-Flights-To-Santa-Isabel.d6035096.Travel-Guide-Flights)[Santa Isabel Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Isabel.d6035096.Car-Hire-Guide)[Santa Isabel Holidays](https://expedia.co.uk/Santa-Isabel.d6035096.Holidays-City-Breaks)

![Aerial view of Wind Turbines in the windfarm of Santa Isabel, Puerto Rico](https://images.trvl-media.com/place/6035096/238893ac-cef3-4b2d-be5e-72d5a4c1868f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6035096/238893ac-cef3-4b2d-be5e-72d5a4c1868f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035096&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[17 Apr - 19 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6035096&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[15 May - 17 May](https://www.expedia.co.uk/Hotel-Search?regionId=6035096&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[12 Jun - 14 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=6035096&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Isabel holiday rentals

![On the beach](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/dee6afa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/d25698dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/d6db4151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/1191238b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stunning Luxury Caribbean Villa – Ocean Views, Infinity Pool & Amazing Sunsets

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Amazing-Caribbean-Boho-Paradise-For-Couples.h120598921.Hotel-Information)

Santa Isabel

£445

includes taxes & fees

5 Mar - 6 Mar

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Amazing-Caribbean-Boho-Paradise-For-Couples.h120598921.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/a475dadd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/a1d9b1f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/d3581209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/9f0e876a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Cultural-Oasis-Beachfront-Gem.h34325198.Hotel-Information)

Santa Isabel

8.8/10

Excellent

(45 reviews)

"It was amazing to be in the center of the culture. Friendly neighbors! Food amazing! Beach’s all around I would definitely stay there again!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Claudine N.

£262

includes taxes & fees

10 Mar - 11 Mar

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Cultural-Oasis-Beachfront-Gem.h34325198.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/65ec3908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/a3a647a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/bb78e3e8_edited_4425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/e6ff84e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Coming and enjoy panoramic views to mountains and sea in Santa Isabel

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Coming-And-Enjoy-Panoramic-Views-To-Mountains-And-Sea-In-Santa-Isabel.h118309772.Hotel-Information)

Santa Isabel

£248

includes taxes & fees

25 Feb - 26 Feb

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Coming-And-Enjoy-Panoramic-Views-To-Mountains-And-Sea-In-Santa-Isabel.h118309772.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/0c933972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/4c52eed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/ec25d784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/2756739a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Palma Serena - Garden Retreat • Tropical Stay

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Santa-Isabel.h123099733.Hotel-Information)

Santa Isabel

£255

includes taxes & fees

24 Feb - 25 Feb

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Santa-Isabel.h123099733.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/3e731efe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/9b169c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/03f05c8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/e1c1b42a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Home-In-Santa-Isabel.h115801590.Hotel-Information)

Santa Isabel

10/10

Exceptional

(2 reviews)

"Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to the property and coordinated a rental car delivery the next morning.The house is a gem in a safe, friendly neighborhood, steps from Walmart and close to dining options. Packed with kid-friendly amenities...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Henry S.

£418

includes taxes & fees

20 Feb - 21 Feb

[](https://www.expedia.co.uk/Santa-Isabel-Hotels-Home-In-Santa-Isabel.h115801590.Hotel-Information)

![Deluxe Mobile Home | Living area](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/2fc3f8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Mobile Home | Living area](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/3ffc6ff5_edited_0a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Mobile Home | Bathroom](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/3d609a94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Cabin | Private kitchen](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/b1ed52e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Gozadera Park

[](https://www.expedia.co.uk/Salinas-Hotels-La-Gozadera-Park.h118212583.Hotel-Information)

Salinas

£108

includes taxes & fees

24 Feb - 25 Feb

[](https://www.expedia.co.uk/Salinas-Hotels-La-Gozadera-Park.h118212583.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/97345936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | Private kitchen | Microwave, cookware/dishes/utensils, paper towels, dining tables](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/10c67684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/ce69cf0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | In-room dining](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/370312d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Place at the Sea

[](https://www.expedia.co.uk/Ponce-Hotels-The-Place-At-The-Sea.h83133987.Hotel-Information)

Ponce

9.4/10

Exceptional

(263 reviews)

"awesome place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

CHRISTOPHER A

[](https://www.expedia.co.uk/Ponce-Hotels-The-Place-At-The-Sea.h83133987.Hotel-Information)

![Deluxe Studio, Multiple Beds | Individually decorated, individually furnished, bed sheets](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/44d9afe0_edited_9568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/8ed8e139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Private kitchen | Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/76820cb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Quadruple Room | Private kitchen | Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/344e0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Playa Apartments

[](https://www.expedia.co.uk/Salinas-Hotels-Playa-Apartments.h7018767.Hotel-Information)

Salinas

7.6/10

Good

(39 reviews)

"Definitely clean, safe, user friendly place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JULIO

£113

includes taxes & fees

24 Feb - 25 Feb

[](https://www.expedia.co.uk/Salinas-Hotels-Playa-Apartments.h7018767.Hotel-Information)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377270/32ec7596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377270/3e47bfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377270/a97ed907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room | Bathroom | Shower, free toiletries, towels](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377270/af6b01e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aibonito Hotel 204

[](https://www.expedia.co.uk/Aibonito-Hotels-Aibonito-Hotel-204.h29377270.Hotel-Information)

Aibonito

7.0/10

Good

(4 reviews)

"At first sight I thought the room was nice and as advertised. Nonetheless, we found two cockroaches in the room, our pillows were old and formless, the bathroom sink's handle came out of its hinges, the showerhead was defective and did not offer a comfortable spread of water and finally they had a scheduled construction right next to our room window and while having other rooms available, failed to inform us and give us a chance to move. The workers woke us up at 8am and they called us at 9:30...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Josue

£75

includes taxes & fees

25 Feb - 26 Feb

[](https://www.expedia.co.uk/Aibonito-Hotels-Aibonito-Hotel-204.h29377270.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/d8c8add6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/90054a0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/a07c2636.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/b6162ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grandpa's lake house lake private access mountain view museum 1950's experience

[](https://www.expedia.co.uk/Cidra-Hotels-Private-Grandpa-House-Lake-Access-And-View-Museum.h92024256.Hotel-Information)

Cidra

9.4/10

Exceptional

(6 reviews)

"We had a great peaceful visit!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelly N.

£89

includes taxes & fees

25 Feb - 26 Feb

[](https://www.expedia.co.uk/Cidra-Hotels-Private-Grandpa-House-Lake-Access-And-View-Museum.h92024256.Hotel-Information)

![Outdoor spa tub](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/0dd88a14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/e8b56baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/ac57be0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/30034394_edited_4c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HW Tiny Home Cidra

[](https://www.expedia.co.uk/Cidra-Hotels-HW-Tiny-Home-Cidra.h105136565.Hotel-Information)

Cidra

10/10

Exceptional

(2 reviews)

"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth C.

£142

includes taxes & fees

24 Feb - 25 Feb

[](https://www.expedia.co.uk/Cidra-Hotels-HW-Tiny-Home-Cidra.h105136565.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/e1240d9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/b12773ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/294858a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/d2e327ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

[](https://www.expedia.co.uk/Cidra-Hotels-Cozy-Studio-With-Private-Pool-And-Bar-Modern-Amentities-Perfect-For-Relaxation.h105454430.Hotel-Information)

Cidra

9.6/10

Exceptional

(4 reviews)

"We have a wonderful time! The pool and bar were perfect!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anna D.

£192

includes taxes & fees

26 Feb - 27 Feb

[](https://www.expedia.co.uk/Cidra-Hotels-Cozy-Studio-With-Private-Pool-And-Bar-Modern-Amentities-Perfect-For-Relaxation.h105454430.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/7172bbbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/cd2da947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/b68c7819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/c647e3ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### RED LOFT VIBE WALKING DISTANCE TO THE CITY

[](https://www.expedia.co.uk/Guayama-Hotels-RED-LOFT-VIBE-WALKING-DISTANCE-TO-THE-CITY.h95987315.Hotel-Information)

Guayama

9.6/10

Exceptional

(5 reviews)

"The best place to spend your days if you visit the city of Guayama, easy access to all the sites of interest in the area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hector

£84

includes taxes & fees

20 Feb - 21 Feb

[](https://www.expedia.co.uk/Guayama-Hotels-RED-LOFT-VIBE-WALKING-DISTANCE-TO-THE-CITY.h95987315.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/3d9cee92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/f5084cc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/c7e903af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/77d0048f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Oasis Salinas 

[](https://www.expedia.co.uk/Salinas-Hotels-Oasis-Salinas.h100431141.Hotel-Information)

Salinas

7.8/10

Good

(13 reviews)

"Excellent place to stay near everything in town "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mayra

£104

includes taxes & fees

22 Feb - 23 Feb

[](https://www.expedia.co.uk/Salinas-Hotels-Oasis-Salinas.h100431141.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/9be3e235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/cab1ca88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/w1177h1400x1y0-4ad24703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/w1176h880x1y0-114edddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

[](https://www.expedia.co.uk/Guayama-Hotels-Cozy-Cabin-With-Hot-Water-Jacuzzi-And-AC-In-The-Mountains-Of-Guayama.h110146312.Hotel-Information)

Guayama

10/10

Exceptional

(2 reviews)

"Property was so beautiful didn’t have any complains. Everything you need in one spot you’d never want to leave."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jonathan

£149

includes taxes & fees

1 Mar - 2 Mar

[](https://www.expedia.co.uk/Guayama-Hotels-Cozy-Cabin-With-Hot-Water-Jacuzzi-And-AC-In-The-Mountains-Of-Guayama.h110146312.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/9f98081f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/5b4d65ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/4c9dfd88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/28313f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nostra Casa Vagón

[](https://www.expedia.co.uk/Villalba-Hotels-Nostra-Casa-Vagon.h121880267.Hotel-Information)

Coamo

10/10

Exceptional

(1 review)

"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos Reyes

£106

includes taxes & fees

22 Feb - 23 Feb

[](https://www.expedia.co.uk/Villalba-Hotels-Nostra-Casa-Vagon.h121880267.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/b969b0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/d8bdd3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/476e3102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/b075f8cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Trinitarias Guest's House's pool/bar/karaoke/wifi

[](https://www.expedia.co.uk/Salinas-Hotels-Vrbo-Property.h109414598.Hotel-Information)

Salinas

10/10

Exceptional

(2 reviews)

"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

julio

£137

includes taxes & fees

10 Mar - 11 Mar

[](https://www.expedia.co.uk/Salinas-Hotels-Vrbo-Property.h109414598.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/91000000/90140000/90134800/90134765/d57b6dc9_edited_1568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/91000000/90140000/90134800/90134765/w448h683x288y0-c585ec5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90140000/90134800/90134765/0eb5e2d1_edited_7281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/91000000/90140000/90134800/90134765/w450h683x287y0-315e683f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### A cozy place to stay walking distance from the beach and Restaurants.

[](https://www.expedia.co.uk/Salinas-Hotels-John-Marinas-Place.h90134765.Hotel-Information)

Salinas

9.4/10

Exceptional

(25 reviews)

"The description of the house is accurate and the cleanliness of the rental was perfect. The neighborhood was amazing with restaurants and access to the water within walking distance. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melanie D.

£115

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Salinas-Hotels-John-Marinas-Place.h90134765.Hotel-Information)

![Comfort Studio | Living area | Smart TV](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/e2e46050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Studio | Living area | Smart TV](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/eab5838c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Studio | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/81e5fad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Studio | Private kitchen | Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/627fd90b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chandelier 301

[](https://www.expedia.co.uk/Ponce-Hotels-Chandelier-301.h29377164.Hotel-Information)

Ponce Centro

7.0/10

Good

(8 reviews)

"Great stay if you are touring the area. Very secured spot and close to a lot of places. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

£116

includes taxes & fees

3 Mar - 4 Mar

[](https://www.expedia.co.uk/Ponce-Hotels-Chandelier-301.h29377164.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/90000000/89510000/89506200/89506180/ac409b44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/90000000/89510000/89506200/89506180/1af39f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi](https://images.trvl-media.com/lodging/90000000/89510000/89506200/89506180/af5f4f35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89506200/89506180/b16674d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Apartment in town - City Dreams Guayama - Great Location

[](https://www.expedia.co.uk/Guayama-Hotels-Cozy-Apartement-In-Town-City-Dreams-Guayama-Great-Location.h89506180.Hotel-Information)

Guayama

8.0/10

Very good

(5 reviews)

"Good "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jose a f.

£97

includes taxes & fees

24 Feb - 25 Feb

[](https://www.expedia.co.uk/Guayama-Hotels-Cozy-Apartement-In-Town-City-Dreams-Guayama-Great-Location.h89506180.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-05&endDate=2026-03-06&regionId=6035096&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Holiday Sale

Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save.

[Book now](https://expedia.co.uk/cheap-deals?rfrr=VR_SPRING_PROMO_6035096)

## Find holiday rentals that suit your style

Private holiday homes

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=VACATION_HOME)

Aparthotels

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=APARTMENT)

Villas

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=VILLA)

Cabins

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=CABIN)

Condos

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=CONDO)

Cottages

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=COTTAGE)

Chalets

[](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=CHALET)

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## Top Santa Isabel Hotel Reviews

![Caribe Hotel Ponce](https://images.trvl-media.com/lodging/1000000/970000/969600/969532/726a9194_y.jpg)

### Caribe Hotel Ponce

10/10 Excellent

"Yes "

[](https://expedia.co.uk/Ponce-Hotels-Spark-By-Hilton-Ponce.h969532.Hotel-Information)

![Hotel Vista Bahia & Marina](https://images.trvl-media.com/lodging/120000000/119570000/119561200/119561199/f4949836_y.jpg)

### Hotel Vista Bahia & Marina

10/10 Excellent

"Clean room, good amenities. Great stay!"

[](https://expedia.co.uk/Salinas-Hotels-Hotel-Vista-Verde-And-Marina.h119561199.Hotel-Information)

![1912 Boutique Hotel](https://images.trvl-media.com/lodging/120000000/119160000/119157000/119156926/35a18024_y.jpg)

### 1912 Boutique Hotel

10/10 Excellent

"The room was spotless and the hotel is beautiful."

[](https://expedia.co.uk/Cayey-Hotels-1912-Boutique-Hotel.h119156926.Hotel-Information)

![Aloft Ponce Hotel & Casino](https://images.trvl-media.com/lodging/58000000/57920000/57918000/57917934/f7ab6c37_y.jpg)

### Aloft Ponce Hotel & Casino

10/10 Excellent

"Staff was awesome Room was clean The restaurants were all excellent. We stayed 5 nights and ate most of our meals there. Having three options was great. Drinks were great! Only issue was parking,,, will be better when the parking deck is finished. Also the music was way too loud at the HRCafe. Couldn’t have a conversation. "

[](https://expedia.co.uk/Ponce-Hotels-Aloft-Ponce.h57917934.Hotel-Information)

![The Place at the Sea](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/97345936_y.jpg)

### The Place at the Sea

10/10 Excellent

"Great location, close to restaurants, bars, and the water. Not beachfront, but not too far of drive from nice beaches. The Delfin room was more than spacious and comfortable for two people. "

[](https://expedia.co.uk/Ponce-Hotels-The-Place-At-The-Sea.h83133987.Hotel-Information)

![Hotel Las Vegas](https://images.trvl-media.com/lodging/29000000/28800000/28799500/28799456/abeca2f0_y.jpg)

### Hotel Las Vegas

10/10 Excellent

"Great experience. "

[](https://expedia.co.uk/Santa-Isabel-Hotels-Motel-Las-Vegas.h28799456.Hotel-Information)

![Holiday Inn Ponce & Tropical Casino by IHG](https://images.trvl-media.com/lodging/1000000/30000/21700/21613/45986a24_y.jpg)

### Holiday Inn Ponce & Tropical Casino by IHG

10/10 Excellent

"Enjoyed the area, we were there for a Family Reunion. "

[](https://expedia.co.uk/Ponce-Hotels-Holiday-Inn-Ponce-Tropical-Casino.h21613.Hotel-Information)

![Hilton Ponce Golf & Casino Resort](https://images.trvl-media.com/lodging/1000000/10000/6400/6322/456e16ff_y.jpg)

### Hilton Ponce Golf & Casino Resort

10/10 Excellent

"Great stay, very clean ! Staff was very friendly and helpful with lots to do on site. Food was good as well !"

[](https://expedia.co.uk/Ponce-Hotels-Hilton-Ponce-Golf-Casino-Resort.h6322.Hotel-Information)

![Hotel Nuevo Mejico](https://images.trvl-media.com/lodging/28000000/27660000/27656400/27656340/42430f9d_y.jpg)

### Hotel Nuevo Mejico

10/10 Excellent

"Great customer service "

[](https://expedia.co.uk/Ponce-Hotels-Motel-Nuevo-Mejico.h27656340.Hotel-Information)

## Find out more about Santa Isabel

**Everything you need to know about** **Santa Isabel** **holiday rentals**

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Santa Isabel holiday rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Isabel holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Santa Isabel holiday rentals we have selected for you start as low as £75 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Santa Isabel rentals**

At Expedia, we put the best Santa Isabel holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

## Explore a world of travel with Expedia

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- [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals)
- [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals)
- [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals)
- [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals)
- [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals)
- [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals)
- [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations)
- [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals)
- [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals)
- [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals)
- [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals)
- [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations)
- [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations)
- [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations)
- [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations)
- [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations)

## Frequently asked questions

### Are there holiday rentals in Santa Isabel?

### What are some of the best holiday rentals that Santa Isabel has to offer?

### How many holiday rentals will I find in Santa Isabel?

### What can I see and do in Santa Isabel?

### What are holiday rentals like in Santa Isabel?

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

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