Title: Cheap Car Hire in Santa Isabel, PRI - Expedia.co.uk [Santa Isabel Travel Guide](https://expedia.co.uk/Santa-Isabel.dx6035096)[Hotels in Santa Isabel](https://expedia.co.uk/Santa-Isabel-Hotels.d6035096.Travel-Guide-Hotels)[Flights to Santa Isabel](https://expedia.co.uk/Cheap-Flights-To-Santa-Isabel.d6035096.Travel-Guide-Flights)[Things to do in Santa Isabel](https://expedia.co.uk/Things-To-Do-In-Santa-Isabel.d6035096.Travel-Guide-Activities)[Santa Isabel Holidays](https://expedia.co.uk/Santa-Isabel.d6035096.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6035096/9acf998c-758c-4442-906a-abe4784b9ebb.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Santa Isabel, PRI ## Search and Compare from Car Companies in Santa Isabel ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Santa Isabel \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Santa Isabel, PRI ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Isabel,%20Puerto%20Rico&dpln=6035096&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Santa Isabel, PRI ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Isabel,%20Puerto%20Rico&dpln=6035096&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Santa Isabel, PRI ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Isabel,%20Puerto%20Rico&dpln=6035096&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Santa Isabel, PRI ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Isabel,%20Puerto%20Rico&dpln=6035096&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Santa Isabel [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Isabel,%20Puerto%20Rico&dpln=6035096&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day in Santa Isabel? ### Can I hire a car from Mercedita Airport (PSE)? ### What happens if I need to cancel my Santa Isabel car reservation? ### What types of cars can I rent in Santa Isabel? ### Where can I go on a road trip from Santa Isabel? > - Jump in the driver's seat and head for San Juan. This thriving city is around 40 miles away and features some memorable attractions, such as San Juan Gate. > - Culebra is another destination that attracts many wanderers. It's about 80 miles from Santa Isabel. Wander around Culebrita Beach first before checking out the city's other sights. ### How do I find the best car hire deals in Santa Isabel with Expedia? ### What do you need to hire a car in Santa Isabel? ### What is the cheapest car hire in Santa Isabel? ### Can I hire a car for a month or longer in Santa Isabel? ### Where can I find a Santa Isabel hire car if I am younger than 25? ### Why should I rent a Santa Isabel car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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