Santa Fe Holidays from £533

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Your Santa Fe Holiday

Our holiday packages to Santa Fe let you customise your own adventure. Tailor your getaway to suit your interests and needs and make the most of your time in this interesting city. Want to explore your surroundings? Alto de Piedra Waterfall, Town Square and Cerro Tute are some of the most popular places to visit during your trip to Santa Fe. Stop daydreaming and start travelling. Browse the wide range of options on Expedia today and finally put your Santa Fe holiday plans into motion!

Top Santa Fe Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Mahogany Suites
Central Hotel Panama Casco Viejo
Villa Marina Lodge & Condos
Dreams Playa Bonita Panama - All Inclusive

Things to do in and around Santa Fe

Santa Fe, Veraguas, is a haven for outdoor enthusiasts, offering stunning scenery and adventure-filled activities. Visitors can indulge in luxurious resorts and rejuvenating spa treatments. Key attractions include sightseeing opportunities, engaging live music, and a vibrant atmosphere perfect for exploring the town. Whether hiking through lush landscapes or enjoying local festivities, Santa Fe promises a memorable experience for all types of travellers.

Shopping

In Santa Fe, you can enjoy shopping at the local Mercado, a vibrant public market. If you're up for a drive, visit Cerámica La Peña and the Artisan Market, both located 46.7km away, offering unique crafts and local goods amidst a lively atmosphere.

Recreation

Experience rejuvenation at Los Pozos Termales, a serene retreat 43.5km from Santa Fe, where soothing thermal waters will melt your stress away. For sports enthusiasts, the Omar Torrijos Herrera Stadium, located 46.7km away, offers a vibrant atmosphere to enjoy local sporting events and activities.

Adventure

Parque Acuatico Italia Guadalupe Panama is a thrilling waterpark located 45.1km from Santa Fe. Enjoy a fun-filled day with family and friends, featuring exciting water slides, pools, and various attractions that guarantee an exhilarating experience for all ages.

Nightlife

Santa Fe boasts a vibrant nightlife with charming venues like the lively Café Santa Fe, perfect for mingling over cocktails. For a more laid-back vibe, visit La Casa de la Cultura, where local music and dance create an enchanting atmosphere, making for a memorable evening.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Santa Fe

Santa Fe, Veraguas, offers an idyllic setting for outdoor enthusiasts and adventure seekers. Explore stunning waterfalls, charming piazzas, and historic churches that provide a perfect backdrop for romance and adventure. Whether you're hiking the scenic trails or enjoying the local culture, Santa Fe's attractions promise a memorable experience. Don't miss out on the delightful activities available to fully appreciate this remarkable destination.

  • Quebrada Las Trancas Spa: Experience a rejuvenating retreat at this natural spa, where adventure meets tranquillity. Nestled in lush surroundings, it offers a unique blend of relaxation and outdoor exploration, allowing you to unwind and connect with nature.
  • Alto de Piedra Waterfall: This stunning waterfall is perfect for outdoor enthusiasts and romantics alike. Surrounded by vibrant flora, it provides a picturesque setting for hiking, swimming, or simply soaking in the beauty of the cascading waters.
  • Town Square: Immerse yourself in the local culture at the Town Square, a lively hub filled with charming shops, cafes, and vibrant street life. It’s the ideal place to experience the essence of Santa Fe and engage with the friendly locals.

Best time to go to Santa Fe

The best time to visit Santa Fe can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Fe falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Santa Fe falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January77.9°F (25.5°C)No RainSunnySlightly HighSlightly Low
February79.7°F (26.5°C)No RainSunnySlightly HighSlightly High
March81.1°F (27.3°C)No RainSunnySlightly HighAverage
April81.5°F (27.5°C)Light RainMostly SunnyAverageAverage
May79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
June78.1°F (25.6°C)Frequent RainMostly CloudySlightly LowSlightly Low
July77.7°F (25.4°C)Frequent RainMostly CloudyAverageAverage
August77.5°F (25.3°C)Frequent RainMostly CloudyAverageAverage
September77.2°F (25.1°C)Frequent RainMostly CloudyAverageAverage
October76.5°F (24.7°C)Frequent RainMostly CloudySlightly LowAverage
November75.9°F (24.4°C)Frequent RainMostly CloudyAverageSlightly High
December76.5°F (24.7°C)Light RainMostly SunnyAverageSlightly High

Tips to save on your trip to Santa Fe

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling to Santa Fe during the low season (January and May to June) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Santa Fe Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
970
Max Temp Winter
32ºC
Max Temp Summer
29ºC
Top Sights
Alto de Piedra Waterfall, Cascada de Bermejo and Town Square

Top hotels in Santa Fe

La Qhia Eco Retreat

La Qhia Eco Retreat

2.5 out of 5
Barriada el Cerro A 100 Mts De Santa Fe Veraguas
8/10 Very Good! (19 reviews)
Nice stay in Santa Fe
Our room had some drawbacks, like many gaps between the roof and walls that enable insects to go inside, but we used our own mosquito net and we were safe to sleep quietly. The second night ants invaded our room, we were offered to be moved to another room, but we were ok with the solution to spray ...

Reviewed on 17 Mar 2025

La Qhia Eco Retreat
Hotel Anachoreo

Hotel Anachoreo

3 out of 5
Calle Chinita Santa Fe Veraguas Province
Fully refundableReserve now, pay when you stay
9.4/10 Exceptional! (38 reviews)
Great stay

Reviewed on 12 Jan 2026

Hotel Anachoreo
Cabana Vergara Santa Fe

Cabana Vergara Santa Fe

2 out of 5
Provincia de Veraguas, Panama Panama
The price is £120 per night from 12 Feb to 13 Feb
£120
12 Feb - 13 Feb
includes taxes & fees
Cabana Vergara Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.