Title: Santa Fe Holidays 2025 from £828 | Expedia.co.uk [Hotels in Santa Fe](https://expedia.co.uk/Santa-Fe-Hotels.d6224616.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe](https://expedia.co.uk/Santa-Fe-Holiday-Rentals.d6224616.Travel-Guide-HolidayRentals)[Santa Fe Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe.d6224616.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6224616/d66c2c6e-894c-41bc-bf7b-56e1db50f42e.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Fe Holidays from £713 ## Book a Hotel + Flight or Car together to unlock savings Photo by Isa - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your Santa Fe Holiday Our holiday packages to Santa Fe let you customise your own adventure. Tailor your getaway to suit your interests and needs and make the most of your time in this interesting city. Want to explore your surroundings? [Alto de Piedra Waterfall](https://www.expedia.co.uk/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Attraction), [Town Square](https://www.expedia.co.uk/Town-Square-Santa-Fe.d6224711.Attraction) and [Cerro Tute](https://www.expedia.co.uk/Cerro-Tute-Santa-Fe.d553248621532965233.Attraction) are some of the most popular places to visit during your trip to Santa Fe. Stop daydreaming and start travelling. Browse the wide range of options on Expedia today and finally put your Santa Fe holiday plans into motion! ## Top Santa Fe Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![MARINN Tropical Vibes Hotel](https://images.trvl-media.com/lodging/91000000/90160000/90152300/90152211/85dc8880_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### MARINN Tropical Vibes Hotel Amador £713 per person 1 Feb - 8 Feb found 6 hours ago Return direct flight included London (LON) to Panama City (PTY) 8.2/10 Very Good! (143 reviews) Room clean and staff friendly Reviewed on 10 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-02-01/2026-02-08/?FromAirport=LON&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=90152211&paandie=true&dealMarker=mGzB9ZsE-1kk29sSPTJpxxdherpk4hFScp0araUb-RTGxwG4Xr5CZY1UfLCv34HW) ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight £1,286 per person 1 Feb - 8 Feb found 6 hours ago Return direct flight included London (LON) to Panama City (PTY) 9/10 Wonderful! (1,005 reviews) Staffs were wonderful. Reviewed on 28 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-02-01/2026-02-08/?FromAirport=LON&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=15683502&paandie=true&dealMarker=J0Y-jfEAGoCdHFgpHa5HlKrC2SMrHy59vMQ75OK0Ovu6gn2G0gYuRshEd6I3htJS) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Las Americas Golden Tower Panama San Francisco £894 per person 1 Feb - 8 Feb found 6 hours ago Return direct flight included London (LON) to Panama City (PTY) 9/10 Wonderful! (1,009 reviews) Wonderful experience and great customer service! Reviewed on 10 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-02-01/2026-02-08/?FromAirport=LON&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=9675263&paandie=true&dealMarker=P2oJBHaqqcX9SJa466RX5M3CWagjhPTZC8zQV0PzroowA1GtZHKfOgP6wjD4MhOP) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive £1,409 per person 1 Feb - 8 Feb found 6 hours ago Return direct flight included London (LON) to Panama City (PTY) 7.4/10 Good! (1,006 reviews) The breakfast was good, good selection, omelet station, great fresh fruit and juice availability. Wait staff were friendly and very service oriented. We will be back. Reviewed on 7 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-02-01/2026-02-08/?FromAirport=LON&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=12445554&paandie=true&dealMarker=41vhLE2ibCDGDjOLdogCsR4Qwh_lrR57FT_Wjami1z_gshIsuwNSQXbaGGdDJPA3) ![MARINN PLACE Financial District](https://images.trvl-media.com/lodging/91000000/90810000/90801900/90801879/c11e781a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### MARINN PLACE Financial District Bella Vista £907 per person 1 Feb - 8 Feb found 6 hours ago Return direct flight included London (LON) to Panama City (PTY) 9.2/10 Wonderful! (296 reviews) Second stay, very nice Reviewed on 7 Nov 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-02-01/2026-02-08/?FromAirport=LON&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=90801879&paandie=true&dealMarker=P2oJBHaqqcX9SJa466RX5M3CWagjhPTZC8zQV0Pzrop50TJC2BQ1IjW4gMltF0GE) ## Santa Fe Essential Information | Language | Spanish | | --- | --- | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Population | 970 | | Max Temp Winter | 32ºC | | Max Temp Summer | 29ºC | | Top Sights | [Alto de Piedra Waterfall](https://www.expedia.co.uk/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Attraction), [Cascada de Bermejo](https://www.expedia.co.uk/Cascada-De-Bermejo-Santa-Fe.d553248621532965237.Attraction) and [Town Square](https://www.expedia.co.uk/Town-Square-Santa-Fe.d6224711.Attraction) | ## Top hotels in Santa Fe ![La Qhia Eco Retreat](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/efe9a595_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Qhia Eco Retreat Barriada el Cerro A 100 Mts De, Santa Fe, Veraguas Fully refundableReserve now, pay when you stay 7.8/10 Good! (18 reviews) Nice stay in Santa Fe Our room had some drawbacks, like many gaps between the roof and walls that enable insects to go inside, but we used our own mosquito net and we were safe to sleep quietly. The second night ants invaded our room, we were offered to be moved to another room, but we were ok with the solution to spray ... Reviewed on 17 Mar 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=24%2F11%2F2025&endDate=25%2F11%2F2025&selected=29430099&PinnedHotelID=29430099&HadPinnedHotel=true®ionId=6224616) [](https://expedia.co.uk/Hotel-Search?startDate=24%2F11%2F2025&endDate=25%2F11%2F2025&selected=29430099&PinnedHotelID=29430099&HadPinnedHotel=true®ionId=6224616) ![Hotel Anachoreo](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Anachoreo Calle Chinita, Santa Fe, Veraguas Province Fully refundableReserve now, pay when you stay 9.4/10 Exceptional! (34 reviews) Exquisite Casita Excellent accommodation: Room, grounds, and common area are beautifully decorated and spotless clean. Staff were friendly & helpful. Only problem was issue with hot water heater the day of our stay. Reviewed on 1 Apr 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=24%2F11%2F2025&endDate=25%2F11%2F2025&selected=27775675&PinnedHotelID=27775675&HadPinnedHotel=true®ionId=6224616) [](https://expedia.co.uk/Hotel-Search?startDate=24%2F11%2F2025&endDate=25%2F11%2F2025&selected=27775675&PinnedHotelID=27775675&HadPinnedHotel=true®ionId=6224616) ![Cabana Vergara Santa Fe](https://images.trvl-media.com/lodging/109000000/108020000/108011300/108011213/w1440h1075x0y422-dda3f8cf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabana Vergara Santa Fe Provincia de Veraguas, Panama, Panama £125 11 Nov - 12 Nov includes taxes & fees [](https://expedia.co.uk/Hotel-Search?startDate=11%2F11%2F2025&endDate=12%2F11%2F2025&selected=108011213&PinnedHotelID=108011213&HadPinnedHotel=true®ionId=6224616) [See all 16 properties in Santa Fe](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=11%2F11%2F2025&endDate=12%2F11%2F2025®ionId=6224616) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit #### Quebrada Las Trancas Spa Commune with nature and explore the great outdoors at Quebrada Las Trancas Spa during your travels in Santa Fe. While you're in the area, wander around the natural setting. [](https://expedia.co.uk/Quebrada-Las-Trancas-Spa-Santa-Fe.d553248635976022318.Attraction) ## Explore a world of travel with Expedia - Accommodation - Packages ### Accommodation - [Calobre Hotels](https://www.expedia.co.uk/Calobre-Hotels.d553248635921599085.Travel-Guide-Hotels) - [San Fransisco District Hotels](https://www.expedia.co.uk/Destinations-In-San-Fransisco-District.d553248635975750662.Hotel-Destinations) - [La Tetilla Hotels](https://www.expedia.co.uk/La-Tetilla-Hotels.d829297219661209600.Travel-Guide-Hotels) - [Remance Hotels](https://www.expedia.co.uk/Remance-Hotels.d829297107396464640.Travel-Guide-Hotels) ### Packages - [Visit Calobre](https://www.expedia.co.uk/Calobre.dx553248635921599085) - [Quebrada Las Trancas Spa](https://www.expedia.co.uk/Quebrada-Las-Trancas-Spa-Santa-Fe.d553248635976022318.Attraction) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)