Title: Santa Fe de Antioquia Travel Guide: Best of Santa Fe de Antioquia, Antioquia Travel 2026 | Expedia.co.uk [Hotels in Santa Fe de Antioquia](https://expedia.co.uk/Santa-Fe-De-Antioquia-Hotels.d6143343.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe de Antioquia](https://expedia.co.uk/Santa-Fe-De-Antioquia-Holiday-Rentals.d6143343.Travel-Guide-HolidayRentals)[Things to do in Santa Fe de Antioquia](https://expedia.co.uk/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities)[Santa Fe de Antioquia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-De-Antioquia.d6143343.Car-Hire-Guide)[Santa Fe de Antioquia Holidays](https://expedia.co.uk/Santa-Fe-De-Antioquia.d6143343.Holidays-City-Breaks) # Santa Fe de Antioquia Travel Guide ## Tourist Guide ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Nice short getaway from Medellín ](https://images.trvl-media.com/place/6143343/01ea9c79-dbb2-489f-a472-444d0cc1b37c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Nice hotel here ](https://images.trvl-media.com/place/6143343/86f5167c-8e76-408a-a433-172b140dfffd.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Fe](https://images.trvl-media.com/place/6143343/027e25da-55d7-4660-bb8e-99afd7963f23.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Fe de Antioquia Where to stay Things to do ### Where to stay in Santa Fe de Antioquia ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Zona Colonial While visiting Zona Colonial, you might make a stop by sights like Cathedral of Santa Fe de Antioquia and Bolivar Square. [](https://expedia.co.uk/Santa-Fe-De-Antioquia-Zona-Colonial.dx553248635976394869) - Top hotels in Santa Fe de Antioquia - Top Holiday Rentals in Santa Fe de Antioquia ![Arde La Selva](https://images.trvl-media.com/lodging/109000000/108290000/108283700/108283692/38d256db_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Arde La Selva km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia £101 19 Feb - 20 Feb additional charges may apply Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ... 9.8/10 Exceptional! (24 reviews) The room was clean, the property was absolutely gorgeous, the staff excells in customer service Reviewed on 16 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=108283692&PinnedHotelID=108283692&HadPinnedHotel=true®ionId=6143343) ![Hotel San Sebastian del Tonusco](https://images.trvl-media.com/lodging/90000000/89940000/89933300/89933227/4fdd9de9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel San Sebastian del Tonusco Carrera 9 Santa Fe de Antioquia Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ... 8.8/10 Excellent! (43 reviews) Two nice swimming calls, very friendly staff, safe, walk to town Reviewed on 20 Nov 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=24%2F02%2F2026&endDate=25%2F02%2F2026&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) [](https://expedia.co.uk/Hotel-Search?startDate=24%2F02%2F2026&endDate=25%2F02%2F2026&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) ![Hotel Boutique Al Alma](https://images.trvl-media.com/lodging/97000000/96670000/96661800/96661794/185fd206_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Boutique Al Alma #9-50 Cra. 8 Santa Fe de Antioquia Antioquia Stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free beach cabanas. Popular attractions Museo Juan del Corral and Bolivar ... 9.4/10 Exceptional! (53 reviews) The stunning ambience, decor and customer service make it a unique and wonderful stay. Reviewed on 4 Feb 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=24%2F02%2F2026&endDate=25%2F02%2F2026&selected=96661794&PinnedHotelID=96661794&HadPinnedHotel=true®ionId=6143343) [](https://expedia.co.uk/Hotel-Search?startDate=24%2F02%2F2026&endDate=25%2F02%2F2026&selected=96661794&PinnedHotelID=96661794&HadPinnedHotel=true®ionId=6143343) [See all 415 properties in Santa Fe de Antioquia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=11%2F02%2F2026&endDate=12%2F02%2F2026®ionId=6143343) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Finca hotel mi refugio](https://images.trvl-media.com/lodging/120000000/119570000/119565600/119565573/07edb325_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Finca hotel mi refugio 1541 Camino real Santa Fé de Antioquia Antioquia Stay at this cottage in Santa Fe de Antioquia. Enjoy free Wi-Fi, free parking and a garden. Popular attractions Museo Juan del Corral and Bolivar Square are ... [](https://expedia.co.uk/Santa-Fe-De-Antioquia-Hotels-Finca-Hotel-Mi-Refugio.h119565573.Hotel-Information) ![SANTA FE DE ANTIOQUIA](https://images.trvl-media.com/lodging/109000000/108750000/108747200/108747191/9b39b471_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### SANTA FE DE ANTIOQUIA 111 Cl. 8 Santa Fe de Antioquia Antioquia Stay at this aparthotel in Santa Fe de Antioquia. Enjoy free Wi-Fi, 6 outdoor pools and a garden. Popular attractions Cathedral of Santa Fe de Antioquia and ... 8/10 Very Good! (1 review) Todo Ok Reviewed on 10 Feb 2025 [](https://expedia.co.uk/Santa-Fe-De-Antioquia-Hotels-SANTA-FE-DE-ANTIOQUIA.h108747191.Hotel-Information) ![Villa Cantaleta Just 3 Block from Old Town](https://images.trvl-media.com/lodging/108000000/107040000/107031200/107031122/60414b0e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Villa Cantaleta Just 3 Block from Old Town Santa Fe de Antioquia Antioquia Stay at this villa in Santa Fe de Antioquia. Enjoy laundry facilities and air conditioning. Popular attractions Casa Atanasio Girardot and Cathedral of Santa ... everything looks as promised in the app, except for the payment options, I ended up paying cash at the location due to technical communication between the app ant the owner Reviewed on 2 Dec 2024 [](https://expedia.co.uk/Santa-Fe-De-Antioquia-Hotels-Villa-Cantaleta-Just-3-Block-From-Old-Town.h107031122.Hotel-Information) [See all properties in Santa Fe de Antioquia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6143343&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Fe de Antioquia hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-10&endDate=2026-02-11)[10 Feb - 11 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-10&endDate=2026-02-11) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-11&endDate=2026-02-12)[11 Feb - 12 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=2026-02-11&endDate=2026-02-12) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6143343&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) ### Popular places to visit #### Bridge of the West After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area. [](https://expedia.co.uk/Bridge-Of-The-West-Antioquia.d553248634304588117.Attraction) #### Bolivar Square Learn about the local history of Santa Fe de Antioquia when you spend time at Bolivar Square. Stroll along the riverfront or experience the area's festivals. [](https://expedia.co.uk/Bolivar-Square-Zona-Colonial.d6264618.Attraction) #### Cathedral of Santa Fe de Antioquia You can learn about the history of Santa Fe de Antioquia when you stop by Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area. [](https://expedia.co.uk/Cathedral-Of-Santa-Fe-De-Antioquia-Zona-Colonial.d6264612.Attraction) #### Iglesia de Santa Bárbara After visiting Iglesia de Santa Bárbara, make a plan to see the other sights and activities in Santa Fe de Antioquia. Wander the riverfront and parks while you're in the area. [](https://expedia.co.uk/Iglesia-De-Santa-Barbara-Zona-Colonial.d553248621532376358.Attraction) #### Casa Atanasio Girardot You can spend an afternoon studying the exhibits at Casa Atanasio Girardot in Santa Fe de Antioquia. [](https://expedia.co.uk/Casa-Atanasio-Girardot-Zona-Colonial.d553248635998043782.Attraction) #### Church of Our Lady of Chinquinquira Church of Our Lady of Chinquinquira is just one of the places to see in Santa Fe de Antioquia, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or visit its monuments. [](https://expedia.co.uk/Church-Of-Our-Lady-Of-Chinquinquira-Zona-Colonial.d6264614.Attraction) ### Things to do ![Santa Fe de Antioquia Tour with Western Bridge Visit](https://mediaim.expedia.com/localexpert/4228231/74b99ee1-9016-4644-94fe-12a3c57f2d3e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe de Antioquia Tour with Western Bridge Visit £28 per adult [](https://expedia.co.uk/things-to-do/santa-fe-de-antioquia-tour-with-western-bridge-visit.a4228231.activity-details) ![Horseback Riding Tour and Coffee Tour with Lunch and Refreshment](https://mediaim.expedia.com/localexpert/50756334/1f9f6580-6b1d-4aa0-be66-471f1a3eed66.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Horseback Riding Tour and Coffee Tour with Lunch and Refreshment £51 per adult [](https://expedia.co.uk/things-to-do/horseback-riding-tour-and-coffee-tour-with-lunch-and-refreshment.a50756334.activity-details) ![Live Santa Fe de Antioquia Guided Tour of the Colonial City](https://mediaim.expedia.com/localexpert/49729125/eb29b7e0-a48d-4473-8a7d-2d17a0f7a703.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Meet "The Mother City", Santa Fe de Antioquia £65 per adult [](https://expedia.co.uk/things-to-do/meet-the-mother-city.a49729125.activity-details) ![Tour Santa Fe de Antioquia](https://mediaim.expedia.com/localexpert/1217678/4d580c9f-6aa7-4f0d-bf00-153337d311f8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tour Santa Fe de Antioquia £112 per adult [](https://expedia.co.uk/things-to-do/tour-santa-fe-de-antioquia.a1217678.activity-details) ![Tour Santa Fe De Antioquia](https://mediaim.expedia.com/localexpert/2116423/fadf707b-a2b6-410c-ac62-66d234d74874.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tour Santa Fe De Antioquia £183 per traveller [](https://expedia.co.uk/things-to-do/tour-santa-fe-de-antioquia.a2116423.activity-details) !["3 plans in 1: Coffee tour in Medellín's mountains, private villa with pool, and visit to the colonial town of Santa Fe de Antioquia(national heritage), and Occidente hanging bridg](https://mediaim.expedia.com/localexpert/50034168/992da70b-a619-4ff1-9894-959cdf5c8229.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Private Villa with Pool, Coffee Farm and Santa Fe de Antioquia! £171 per adult [](https://expedia.co.uk/things-to-do/private-villa-with-pool.a50034168.activity-details) [See all activities in Santa Fe de Antioquia](https://expedia.co.uk/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities) ## Cities near Santa Fe de Antioquia ![Sopetrán, Antioquia, Colombia; June 29, 2024: Ceiling interior details of Our Lady of the Assumption in the main square of Sopetrán town.](https://images.trvl-media.com/place/3000006094/2656bb7d-5503-45f6-ae38-4003a1e0d109.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Sopetrán - Cities near Santa Fe de Antioquia [Sopetrán](https://expedia.co.uk/Sopetran.dx3000006094) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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