Title: TOP Business Hotels in Santa Fe Island for 2026 | Expedia.co.uk [Santa Fe Island Travel Guide](https://expedia.co.uk/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.co.uk/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe Island](https://expedia.co.uk/Santa-Fe-Island-Holiday-Rentals.d6336630.Travel-Guide-HolidayRentals)[Flights to Santa Fe Island](https://expedia.co.uk/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Santa Fe Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-Island.d6336630.Car-Hire-Guide)[Santa Fe Island Holidays](https://expedia.co.uk/Santa-Fe-Island.d6336630.Holidays-City-Breaks) ![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Elizabeth Oates ![](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Fe Island Business Hotels Tonight [9 Mar - 10 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-03-09&endDate=2026-03-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [10 Mar - 11 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Santa Fe Island business-friendly hotels ![Breakfast, dinner served; local and international cuisine, sea views ](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f2307f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/a685ce77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/5dea777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double or Twin Room | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f92aa86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ikala Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (136 reviews) "Gorgeous property and wonderful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robyn £181 27 Mar - 28 Mar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/f83773fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/d5ba3cfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/48f9ccf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/6b34c8d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blu Galapagos Sustainable Waterfront Lodge [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) Puerto Ayora 8.8/10 Excellent (126 reviews) "Beautiful property " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David £206 13 Mar - 14 Mar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/7c8dc193.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/27568355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/e0c0b34a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/f3ace51e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suymar Ecolodge Galapagos [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Suymar-Ecolodge-Galapagos.h14734307.Hotel-Information) Bella Vista 9.2/10 Wonderful (18 reviews) "Incredible stay - would highly recommend this to anyone looking to stay a little out of the port area but not too far" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Porcia [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Suymar-Ecolodge-Galapagos.h14734307.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/2a617ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Quadruple Room, Private Bathroom | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/e31c7b0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/4a7fc99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/2e4ce3f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Deja Vu [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-HOTEL-DEJA-VU.h16760931.Hotel-Information) Puerto Ayora 7.6/10 Good (29 reviews) "excellent service, the staff is very friendly 🙂 good location, you can walk to the main street" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Danaee [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-HOTEL-DEJA-VU.h16760931.Hotel-Information) ![Standard Triple Room | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/2ca19af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/64e7ee10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Bathroom | Shower, free toiletries, hair dryer, slippers](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/e94fe441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/d088e7ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capitan Max B&B [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) Puerto Ayora 9.8/10 Exceptional (216 reviews) "Clean , friendly staff, accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/926c680e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/590d85d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/w2236h1687x0y0-81876455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Finch Bay Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) Puerto Ayora 9.2/10 Wonderful (93 reviews) "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £492 18 Mar - 19 Mar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/ca3d4359.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/b42c7514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/9894ff2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Single Beds | Down duvets, desk, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/fb031bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lava House Hostal [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Lava-House-Hostal.h17516766.Hotel-Information) Puerto Ayora 9.4/10 Exceptional (53 reviews) "I stayed here twice. Both times highly satisfactory. Staff was very friendly and accommodatding. The rooms and garden area are in excellent upkeep and pleasant to hang out in hammocks or seating arrangements. The owners are very kind people, who even helped me organize a free ride back to the airport upon my departure (a relative happened to also take a flight off the island). I highly recommend this establishment. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irmgard [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Lava-House-Hostal.h17516766.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/15773cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/a0cfc072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/638e859c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/7411fddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Solymar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Solymar.h4460518.Hotel-Information) Puerto Ayora 7.8/10 Good (59 reviews) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VISHAL [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Solymar.h4460518.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/5979c959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, individually furnished, desk](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/5f9e5a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/e303d191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Local cuisine](https://images.trvl-media.com/lodging/14000000/13110000/13104300/13104250/514bb8aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palo Santo Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Palo-Santo-Galapagos-Hotel.h13104250.Hotel-Information) Puerto Ayora 8.4/10 Very good (22 reviews) "Very attentive staff and large clean room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kay £177 19 Mar - 20 Mar [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Palo-Santo-Galapagos-Hotel.h13104250.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/14000000/13120000/13118100/13118063/5e778db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/14000000/13120000/13118100/13118063/6e6b9c25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/14000000/13120000/13118100/13118063/a366ddc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/14000000/13120000/13118100/13118063/ea42eab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Dreams Galapagos [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ocean-Dreams-Galapagos.h13118063.Hotel-Information) Puerto Ayora 8.8/10 Excellent (41 reviews) "friendly staff and good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chong £68 10 Apr - 11 Apr [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ocean-Dreams-Galapagos.h13118063.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25®ionId=6336630&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6336630) ## Top Santa Fe Island Hotel Reviews ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/48310af4_y.jpg) ### Hotel el descanso del Guia 8/10 Good "The staff was amazing, so attentive and kind!" 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