Title: Santa Cruz Holidays 2026 from £504 | Expedia.co.uk [Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d829296801610752000.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d829296801610752000.Travel-Guide-HolidayRentals)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d829296801610752000.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Cruz Holidays from £504 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Santa Cruz Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Summit Rainforest & Golf Resort](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/a96760ad_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Summit Rainforest & Golf Resort £504 per person 20 Apr - 24 Apr found 19 hours ago Return flight included Port of Spain (POS) to Panama City (PTY) 8.4/10 Very Good! (1,001 reviews) Really neat location and would go back soley based on the outdoor activities but the place was a bit unorganized and cleanliness and upkeep were not the best. It was still good though. I would not avoid it, just manage some expectations and then have a great time :) The animal refuge and butterfly tour are well worth every minute Reviewed on 18 Feb 2026 ![Villa Marina Lodge & Condos](https://images.trvl-media.com/lodging/10000000/9550000/9542300/9542280/8ba948e1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Marina Lodge & Condos £943 per person 13 May - 20 May just found Return direct flight included London (LON) to Panama City (PTY) 9/10 Wonderful! (133 reviews) J’ai tout aimé de l’endroit qui était féerique, tranquille, directement sur le bord de la plage. Le personnel impeccable et la chambre parfaite et confortable 😊 Reviewed on 23 Feb 2026 ![Casa Contemporanea by Wynwood House](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Contemporanea by Wynwood House Casco Viejo £608 per person 20 Apr - 24 Apr found 19 hours ago Return flight included Port of Spain (POS) to Panama City (PTY) 8.6/10 Excellent! (19 reviews) Cute place, well located. Reviewed on 21 Feb 2026 ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia £581 per person 20 Apr - 24 Apr found 19 hours ago Return flight included Port of Spain (POS) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on 26 Jul 2025 ![La Cuadra by Wynwood House ](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/b4a2ec38_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Cuadra by Wynwood House El Chorrillo £551 per person 20 Apr - 24 Apr found 19 hours ago Return flight included Port of Spain (POS) to Panama City (PTY) 9.2/10 Wonderful! (42 reviews) Superb customer service. Instant responsiveness. Almost miraculous. Reviewed on 4 Feb 2026 ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=PKG_SPRING_PROMO_829296801610752000) ## Top hotels in Santa Cruz ![Bocas del Mar Hotel](https://images.trvl-media.com/lodging/6000000/5380000/5374400/5374312/b859ba26_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Bocas del Mar Hotel Road to Boca Chica Boca Chica Chiriqui £204 2 Mar - 3 Mar includes taxes & fees 9.6/10 Exceptional! (225 reviews) We had an amazing time at Bocas del Mar. The entire staff is courteous, kind and helpful. Our airline delayed our bags. Since the closest commercial area is 1 hr away, I was very stressed because I had none of our belongings l, including our kids swim gear. I spent so many hours reaching out to the ... Reviewed on 19 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F03%2F2026&endDate=03%2F03%2F2026&selected=5374312&PinnedHotelID=5374312&HadPinnedHotel=true®ionId=829296801610752000) ![Show Pony Ranchero Resort - Boutique Beach Hotel](https://images.trvl-media.com/lodging/20000000/19710000/19703700/19703609/0d43775a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Show Pony Ranchero Resort - Boutique Beach Hotel Jobo Las Lajas Chiriqui Fully refundableReserve now, pay when you stay £90 30 Mar - 31 Mar includes taxes & fees [](https://expedia.co.uk/Hotel-Search?startDate=30%2F03%2F2026&endDate=31%2F03%2F2026&selected=19703609&PinnedHotelID=19703609&HadPinnedHotel=true®ionId=829296801610752000) ![Las Lajas Beach Resort](https://images.trvl-media.com/lodging/18000000/17730000/17721700/17721674/25717d07_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Las Lajas Beach Resort Playa Las Lajas Las Lajas Chiriqui 9.2/10 Wonderful! (138 reviews) Great place for a beach stay in Panama. We loved the resort,the staff,the beach. Keep in mind this is a more rustic area,but the value here is terrific. We really enjoyed it. Also food and drinks are very reasonably priced,and very good. Reviewed on 26 Mar 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=17721674&PinnedHotelID=17721674&HadPinnedHotel=true®ionId=829296801610752000) [](https://expedia.co.uk/Hotel-Search?startDate=14%2F03%2F2026&endDate=15%2F03%2F2026&selected=17721674&PinnedHotelID=17721674&HadPinnedHotel=true®ionId=829296801610752000) [See all 42 properties in Santa Cruz](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=01%2F03%2F2026&endDate=02%2F03%2F2026®ionId=829296801610752000) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app