Santa Cruz Holidays from £1,219

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    Save up to £335 when you book a flight and hotel together*
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Your Santa Cruz Holiday

There's no better way to get away than with one of our holiday packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like Lapostolle Clos Apalta Winery, Laura Hartwig Winery and Casino Colchagua. Your perfect Santa Cruz holiday is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you.

Top Santa Cruz Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
The Hip Hotel

The Hip Hotel

3.5 out of 5
Bellavista
per person
18 Oct - 21 Oct
found 21 hours ago
Return flight included
Inverness (INV) to Santiago (SCL)
9.6/10 Exceptional! (24 reviews)
The Place is Groovy…situated above many place to eat and drink. Staff was amazing. Breakfast was made will care, even the cook came out to make sure my eggs were prepared well.

Reviewed on 31 Jul 2025

Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Las Condes
per person
18 Oct - 21 Oct
found 21 hours ago
Return flight included
Inverness (INV) to Santiago (SCL)
9.2/10 Wonderful! (871 reviews)
Fantastic experience. Staff were so kind and made a real extra effort to celebrate my birthday. Great food. Just a notch above in every area!

Reviewed on 2 Aug 2025

ICON Hotel

ICON Hotel

4 out of 5
Las Condes
per person
18 Oct - 21 Oct
found 21 hours ago
Return flight included
Inverness (INV) to Santiago (SCL)
8.6/10 Excellent! (1,000 reviews)
Good ,Modern , bar resaurant and at the top of the building mind Blowing 🇦🇼😎

Reviewed on 23 Jul 2025

Hotel Eco Boutique Bidasoa

Hotel Eco Boutique Bidasoa

4 out of 5
Vitacura
per person
18 Oct - 21 Oct
found 21 hours ago
Return flight included
Inverness (INV) to Santiago (SCL)
9.2/10 Wonderful! (222 reviews)
Fantastic property near the main attractions but far enough for calm and tranquility.

Reviewed on 23 Jul 2025

Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Providencia
per person
18 Oct - 21 Oct
found 21 hours ago
Return flight included
Inverness (INV) to Santiago (SCL)
9/10 Wonderful! (716 reviews)
Jorge was great also a lady manager was amazingly helpful! I can’t remember her name!

Reviewed on 4 Aug 2025

Santa Cruz Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
33,300
Max Temp Winter
16ºC
Max Temp Summer
32ºC
Top Sights
Lapostolle Clos Apalta Winery, Museo de Colchagua and MontGras Winery

Top hotels in Santa Cruz

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
The price is £81 per night from 18 Aug to 19 Aug
£81
18 Aug - 19 Aug
8.6/10 Excellent! (314 reviews)
"The hotel truly shines with its exceptional cleanliness and a refined design that takes inspiration from the Chilean countryside"

Reviewed on 6 Jun 2025

Santa Cruz Plaza
TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
The price is £85 per night from 7 Aug to 8 Aug
£85
7 Aug - 8 Aug
9.2/10 Wonderful! (196 reviews)
"We were greeted by Rosita who was the most lovely hostess ever. She had our rooms ready early and adjusted to our requests. She ALSO made a Dr appointment for one of our party at a great local clinic. AND she let me park my car there for a few days while we made our trip to ski in Chillan. Rosita ..."

Reviewed on 15 Jul 2025

TerraViña
Hotel Cava Colchagua

Hotel Cava Colchagua

4 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
8.8/10 Excellent! (160 reviews)
"Fun, interesting, pools ice cold, dogs barking all night. Still you don’t want to miss this opportunity."

Reviewed on 29 Mar 2025

Get rates
Hotel Cava Colchagua
See all 54 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Cruz

Peralillo Chapel

Moment Tour Tasting

£16
per adult
Moment Tour Tasting
Customers

Moment Premium Tasting Tour

£29
per adult
Moment Premium Tasting Tour
Make Your Own Wine & Guided Vineyard Tour

Make Your Own Wine & Guided Vineyard Tour

£35
per adult
Make Your Own Wine & Guided Vineyard Tour
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz travel package cost?
The most affordable Santa Cruz travel package is £1,219, so your dream holiday can become a reality — without a hefty price tag. Bundle flights, hotels and car rentals to customize a package that matches your travel style.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
We totally understand — the universe can throw the odd curveball. If you've booked a Santa Cruz travel package and have to cancel or change it, we can help. We recommend looking up our Customer Service Portal first for information. But in general, if you've booked your package within 24 hours, you may be able to cancel or amend your itinerary free of charge. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a fee.
How do I get a cheap travel package to Santa Cruz?
Track down flights that fit your schedule, add a hotel room to your booking and watch the savings grow with a Santa Cruz travel package. It's that easy! From flights and hotels to rental cars and activities, Expedia is your gateway to cheap travel. And with over 550 partner airlines and 1,000,000 hotel options globally to choose from, you won't be short of choice.
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Expedia has partnered with online lender Klarna to make booking your next getaway a bit easier on the wallet. Paying in instalments means you can spread the costs of your next big adventure, leaving you with more money to play with while you're travelling. Klarna has several payment plans to pick from, so you're sure to find something that suits your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna offers just that! Paying in convenient monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay off your trip over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the total upfront) makes it easier to hit that "book now" button, choose a low deposit holiday payment plan from Klarna.

Where should I stay in Santa Cruz?
A getaway to Santa Cruz isn't complete without visiting Museo de Colchagua, Lapostolle Clos Apalta Winery and Laura Hartwig Winery. Spend your evenings close to these popular sights and make sightseeing a breeze.
What are the top hotels in Santa Cruz?
Make a reservation at TerraViña. It's one of this neighbourhood's most popular hotels. Another well-known option in Santa Cruz is Noi Blend Colchagua.
How far in advance should I book my Santa Cruz holiday?
While not all air carriers advertise tickets early, customers are usually able to start comparing international airfares on Expedia up to 12 months in advance. This is when you'll bag some fantastic bargains. If you've left everything to the last minute, you might still get lucky. Sometimes the lowest prices become available only weeks prior to departure.
What does an Expedia Santa Cruz travel package include?
Choose from any combination of hotels, flights and rental cars. Once you've made your booking, you can also add on activities and experiences. Want to pick your airfare class? That's easily done too. The choice is yours when it comes to organising your perfect Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
Whether it's adventure or relaxation you're craving, a Santa Cruz travel package lets you organise your escape your way. Plus, you'll score great discounts when you combine your accommodation with your rental car and flights. The more you bundle, the bigger the savings!
Can I choose my airline with a Santa Cruz Expedia travel package?
With a travel package, you're in charge. Whether you're eager to fly to Santa Cruz in business or coach, simply choose from the available airline options. Expedia has access to more than 550 partner airlines across the world.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.