Santa Cruz Holidays from £1,297
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santa Cruz Holiday
There's no better way to get away than with one of our holiday packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like Lapostolle Clos Apalta Winery, Laura Hartwig Winery and Casino Colchagua. Your perfect Santa Cruz holiday is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you.
Top Santa Cruz Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Hotel Las Majadas
Price was £1,879, price is now £1,438 per person
£1,438
per person
15 Jul - 21 Jul
found 1 day ago
Return flight included
Birmingham (BHX) to Santiago (SCL)
9.8/10 Exceptional! (111 reviews)
Hotel was a lovely relaxing trip.
Food in restaurant was delicious and well presented .
Rooms were lovely and quiet.
Grounds were wonderful and well kept.
Reviewed on 8 Mar 2026
Hotel Casa Real Viña Santa Rita
Price was £2,350, price is now £1,920 per person
£1,920
per person
15 Jul - 21 Jul
found 1 day ago
Return flight included
Birmingham (BHX) to Santiago (SCL)
9.8/10 Exceptional! (85 reviews)
Unique property next to a winery and in the middle of a vineyard. Very special.
Reviewed on 20 Apr 2026
Hotel Boutique Castillo Rojo
Bellavista
Price was £1,593, price is now £1,357 per person
£1,357
per person
15 Jul - 21 Jul
found 1 day ago
Return flight included
Birmingham (BHX) to Santiago (SCL)
9.6/10 Exceptional! (720 reviews)
The staff were amazing, so kind and helpful, so hospitable. The property is gorgeous, everything is beautiful and thoughtfully arranged. It was such a comfortable and authentic stay. They also went above and beyond for my daughter's 21st birthday with a surprise when we arrived. We will absolutely stay here again when we return to Chile someday.
Reviewed on 29 Apr 2026
Santa Cruz Essential Information
Language | Spanish |
|---|---|
Currency | Chilean pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 33,300 |
Max Temp Winter | 16ºC |
Max Temp Summer | 32ºC |
Top Sights | Lapostolle Clos Apalta Winery, Museo de Colchagua and MontGras Winery |
Top hotels in Santa Cruz
Santa Cruz Plaza
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is £116 per night from 10 May to 11 May
£116
10 May - 11 May
Hotel Cava Colchagua
Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is £108 per night from 15 May to 16 May
£108
15 May - 16 May
La Perla Hotel
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
The price is £62 per night from 5 May to 6 May
£62
5 May - 6 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa Cruz
Viu Manent and Montes Winery, Colchagua Valley from semi-private
£206
per adult
Explore a world of travel with Expedia
- 5 Star Hotels in Colchagua Valley Wine Route
- Baños Hotels
- Chimbarongo Hotels
- Codegua Hotels
- Country Houses in Colchagua
- Farmstay in Colchagua Valley Wine Route
- Cabin Rentals in Colchagua Valley Wine Route
- Chalets in Colchagua Valley Wine Route
- Resorts in Colchagua Valley Wine Route
- Boutique Hotels in Colchagua Valley Wine Route
- Cheap Hotels in Colchagua Valley Wine Route
- Casino Hotels in Colchagua Valley Wine Route
- Family-Friendly Hotels in Colchagua Valley Wine Route
- Golf Hotels in Colchagua Valley Wine Route
- Historic Hotels in Colchagua Valley Wine Route
- Luxury Hotels in Colchagua Valley Wine Route
- Mountain Hotels in Colchagua Valley Wine Route
- Pet-Friendly Hotels in Colchagua Valley Wine Route
- Romantic Hotels in Colchagua Valley Wine Route
- Spa Hotels in Colchagua Valley Wine Route
- Winery Hotels in Colchagua Valley Wine Route
- Colchagua Valley Wine Route Hotels
- Coltauco Hotels
- Cunaco Hotels
- Cachapoal Province Hotels
- Hotels with Parking in Colchagua
- Lakeside Hotels in Colchagua
- Riverside Hotels in Colchagua
- Colchagua Hotels
- O'higgins Region Hotels
- Doñihue Hotels
- El Durazno Hotels
- Graneros Hotels
- La Boca Hotels
- La Estrella Hotels
- Las Cabras Hotels
- Lolol Hotels
- Machalí Hotels
- Machali Hotels
- Malloa Hotels
- Manzano Hotels
- Marchihue Hotels
- Matanzas Hotels
- Hotels near Monticello Grand Casino and Convention Center
- Mostazal Hotels
- Nancagua Hotels
- Navidad Hotels
- Palmilla Hotels
- Pelequen Hotels
- Peralillo Hotels
- Peumo Hotels
- Pichilemu Hotels
- Placilla Hotels
- Población Errázuriz Hotels
- Puertecillo Hotels
- Pupuya Hotels
- Quinta de Tilcoco Hotels
- Rancagua Hotels
- Rengo Hotels
- All-Inclusive Hotels in San Fernando
- San Fernando Hotels
- San Vicente Hotels
- Sewell Hotels
- Topocalma Hotels
- Colchagua Valley Wine Route Holidays
- Visit Colchagua Valley Wine Route
- Gosan Class Classic Motorcycle Museum
- Hacienda El Huique
- Lago Rapel
- Visit Lolol
- Visit Nancagua
- Visit O'Higgins Region
- Visit Pichidegua
- Visit Pichilemu
- San Fernando Holidays
- Sewell Holidays
- Adults Only Holiday Packages Colchagua Valley Wine Route
- Luxury Holiday Packages Colchagua Valley Wine Route
- Mountain Holiday Packages Colchagua Valley Wine Route
- Romantic Holiday Packages Colchagua Valley Wine Route
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
