Santa Cruz Holidays from £938

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Your Santa Cruz Holiday

An easy way to experience this unique city is with a custom-made Santa Cruz holiday package. Base yourself in the neighbourhood of La Candelaria, which is good for dining, history and shopping or go someplace else — our packages are all about you. Every trip to Santa Cruz needs a well-thought-out itinerary. Fill yours with major attractions such as Atanasio Giradot Stadium, Botero Plaza and Lights Park. A couple of quick clicks is all it takes to build your dream Santa Cruz holiday on Expedia.

Top Santa Cruz Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
4 Sur Hotel

4 Sur Hotel

3 out of 5
Guayabal
Price was £1,173, price is now £938 per person
£938
per person
18 Jun - 24 Jun
found 9 hours ago
Additional charges may apply
Return flight included
London (LHR) to Medellín (MDE)
9.4/10 Exceptional! (222 reviews)
My week there was enjoyable. Breakfast was delicious each day. Staff was attentive and the neighborhood was full of local shops and restaurants

Reviewed on 30 Mar 2026

Aparta Suites Torre Poblado

Aparta Suites Torre Poblado

3 out of 5
El Poblado
Price was £1,268, price is now £985 per person
£985
per person
18 Jun - 24 Jun
found 9 hours ago
Additional charges may apply
Return flight included
London (LHR) to Medellín (MDE)
8.8/10 Excellent! (890 reviews)
The staff was absolutely amazing! Everyone at the hotel are very attentive. Breakfast is great! Nice view and location! Would stay again for sure!

Reviewed on 8 Apr 2026

Selvario 36 Hotel

Selvario 36 Hotel

4 out of 5
El Poblado
Price was £1,407, price is now £1,102 per person
£1,102
per person
18 Jun - 24 Jun
found 9 hours ago
Additional charges may apply
Return flight included
London (LHR) to Medellín (MDE)
9.4/10 Exceptional! (673 reviews)
Breakfast was good but took very long to order and arrive. Over an hour on 2 occasions. We did not use the spa treatment that was included with our rooms. Availability was very limited and they also cancelled the one time we were able to get an appointment.

Reviewed on 10 Apr 2026

Binn Hotel

Binn Hotel

5 out of 5
El Poblado
Price was £1,392, price is now £1,103 per person
£1,103
per person
18 Jun - 24 Jun
found 9 hours ago
Additional charges may apply
Return flight included
London (LHR) to Medellín (MDE)
9.2/10 Wonderful! (1,000 reviews)
We've stayed there 7-8 times now. We obviously love it for the great food from both the upstairs and downstairs restaurants, the jacuzzi/ large hot tub (?), and the incredible staff. We've been very blessed to get to know them and enjoy staying here bc of them, an feeling like we are safe staying there.

Reviewed on 8 Apr 2026

23Hotel Medellin

23Hotel Medellin

3.5 out of 5
El Poblado
Price was £1,386, price is now £1,111 per person
£1,111
per person
18 Jun - 24 Jun
found 9 hours ago
Additional charges may apply
Return flight included
London (LHR) to Medellín (MDE)
9.4/10 Exceptional! (368 reviews)
Staff was very friendly and accommodating, me and my friends were able to get rooms together. It felt like we had the whole floor to ourselves. I like that every room is unique and decorated nicely, the bed was really comfortable and the rooms were very clean. I really loved this hotel, it looked exactly like the pictures, the roof top pool was great and so was the breakfast. I really felt at home here, I would definitely recommend! Also, the location is close to Provenza and within walking distance to a lot of restaurants and bars.

Reviewed on 10 Apr 2026

Santa Cruz Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)
Max Temp Winter
21ºC
Max Temp Summer
24ºC
Top Sights
Pueblito Paisa, Antioquia Museum and Explora Park

Top hotels in Santa Cruz

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
The price is £39 per night from 15 Apr to 16 Apr
£39
15 Apr - 16 Apr
additional charges may apply
9/10 Wonderful! (722 reviews)
Everything was great

Reviewed on 12 Apr 2026

Calle Flora Hotel by Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
The price is £51 per night from 26 Apr to 27 Apr
£51
26 Apr - 27 Apr
additional charges may apply
8.8/10 Excellent! (1,871 reviews)
Ok

Reviewed on 12 Apr 2026

Hotel Dorado La 70
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

4 out of 5
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
The price is £49 per night from 5 May to 6 May
£49
5 May - 6 May
additional charges may apply
9.2/10 Wonderful! (1,867 reviews)
Experiencia decepcionante. El servicio al huésped claramente no es prioridad. Desde el check-in la orientación es pobre: no explican que el elevador funciona con la llave, que solo incluyen 2 botellas de agua (luego se pagan), ni que el “cóctel de bienvenida” es uno específico. Falta total de comunicación. ...

Reviewed on 12 Apr 2026

Hashtag 98 Hotel By Jalo
See all 4,197 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Santafé Mall

Santafé Mall

4/5(5 reviews)

During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Visit the top-notch restaurants or lively bars in this walkable area.

Santafé Mall
Botero Plaza

Botero Plaza

4.5/5(9 reviews)

Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants.

Botero Plaza
Pueblito Paisa

Pueblito Paisa

3.5/5(2 reviews)

Take a trip back in time to a replica of a typical old town from the region with a stunning view of the new city.

Pueblito Paisa

What to do in Santa Cruz

Pablo Escobar Tour Medellin

Pablo Escobar Tour : Museum, History and Beer

£30
per adult
90% of travellers recommend
Pablo Escobar Tour : Museum, History and Beer
Medellín: Comuna 13 District Tour with Cable Car Ride

Medellín: Comuna 13 District Tour with Cable Car Ride

£20
per adult
98% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
See all activities in Santa Cruz

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.