Santa Cruz Holidays

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Your Santa Cruz Holiday

An easy way to experience this unique city is with a custom-made Santa Cruz holiday package. Base yourself in the neighbourhood of La Candelaria, which is good for dining, history and shopping or go someplace else — our packages are all about you. Every trip to Santa Cruz needs a well-thought-out itinerary. Fill yours with major attractions such as Atanasio Giradot Stadium, Botero Plaza and Lights Park. A couple of quick clicks is all it takes to build your dream Santa Cruz holiday on Expedia.

Santa Cruz Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)
Max Temp Winter
21ºC
Max Temp Summer
24ºC
Top Sights
Pueblito Paisa, Antioquia Museum and Explora Park

Top hotels in Santa Cruz

Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is £55 per night from 19 Jul to 20 Jul
£55
19 Jul - 20 Jul
additional charges may apply
9.2/10 Wonderful! (1,650 reviews)
"hotel is nice and fairly new. it was a great hotel, but now the rooms smell like crap from the shower drainage and toilet."

Reviewed on 12 Jul 2026

Heiss Hotel By Jalo
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
The price is £118 per night from 24 Jul to 25 Jul
£118
24 Jul - 25 Jul
additional charges may apply
9/10 Wonderful! (1,121 reviews)
"B"

Reviewed on 12 Jul 2026

Calle Flora Hotel by Jalo
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

4.5 out of 5
Carrera 43a No.7-50, Avenida El Poblado Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is £67 per night from 20 Jul to 21 Jul
£67
20 Jul - 21 Jul
additional charges may apply
9/10 Wonderful! (1,913 reviews)
"Nunca limpiaron el baño"

Reviewed on 12 Jul 2026

Dann Carlton Medellin Hotel
See all 4,563 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Cruz

Tour to Guatape, Piedra del Peñol, lunch, snacks boat trip

Tour to Guatape, Piedra del Peñol, lunch, snacks boat trip

£34
per adult
94% of travellers recommend
Tour to Guatape, Piedra del Peñol, lunch, snacks boat trip
Day tour to Guatapé +Rock del Peñol: Breakfast, Lunch and Boat.

Guatapé,la Piedra,crucero con vista a casa de famos &comidas

£29
per adult
98% of travellers recommend
Guatapé,la Piedra,crucero con vista a casa de famos &comidas
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz travel package cost?
From as little as . Yes, you read that correctly. Our Santa Cruz travel packages are a simple way to make your budget stretch further. Bundle your favourite flights, hotels and rental car and explore this vibrant destination.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Don't worry if you're rethinking your Santa Cruz travel package — you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We realise your circumstances can change suddenly, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we're ready to help.
How do I get a cheap travel package to Santa Cruz?
Creating your own Santa Cruz holiday package with Expedia is the easiest way to save. We offer more than 550 air carriers and 1,000,000 hotel options all over the world. With such a fabulous range to choose from, you'll have no difficulty putting together your dream holiday.
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Your bank balance shouldn't prevent you from going on holiday, so Expedia has worked out a solution to help. Now that we've partnered with online lender Klarna, it's easier than ever to book a fabulous getaway without hurting your hip pocket. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your trip. Check out these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month is what works best for you, Klarna can help. Paying in convenient monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay for your holiday in multiple transactions.
  • Low deposit holidays: Clicking on the "book now" button is easier with this payment plan. Just put down a small deposit on your holiday and then start working on your travel plans.

Where should I stay in Santa Cruz?
A trip to Santa Cruz isn't complete until you've seen Atanasio Giradot Stadium and Botero Plaza. Stay at a hotel right nearby so you can easily access these famous attractions.
What are the top hotels in Santa Cruz?
Book a room at Dann Carlton Medellin Hotel. It's one of the neighbourhood's most sought-after hotels. Another well-known option in Santa Cruz is The Charlee Hotel.
How far in advance should I book my Santa Cruz holiday?
It can be hard to know exactly when the best time is to book your trip to Santa Cruz. But generally the earlier you book, the lower the prices. In some cases, you can reserve your flights and hotels nearly a year before departure. If you're considering a last-minute getaway, no need to fret! There are great bargains advertised on Expedia every single day.
What does an Expedia Santa Cruz travel package include?
With Expedia, you can select a combination of flights, car rentals and hotels to build your ideal Santa Cruz travel package. Once you've made your booking, you can add on the fun stuff like tours and experiences. Remember — the more you bundle, the more cash you'll save!
What should I know before booking a Santa Cruz travel package?
You can look forward to saving with an Expedia travel package. Bundle your airfares, rental cars and hotels and land fabulous discounts. You're not limited to hotels, however. We have oceanfront condos, city apartments and even ranches and treehouses!
Can I choose my airline with a Santa Cruz Expedia travel package?
Yes — that's one of the best things about an Expedia travel package. You're the boss! We have access to more than 550 partner airlines around the world, so you have lots of choice when putting together your Santa Cruz trip.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.