Santa Cruz Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Santa Cruz Essential Information

Language
Spanish
Currency
Peruvian sols
Local Welcome
¡Hola!
Local Goodbye
Adiós
Max Temp Winter
32ºC
Max Temp Summer
32ºC

Top hotels in Santa Cruz

DoubleTree by Hilton Iquitos

DoubleTree by Hilton Iquitos

5 out of 5
Napo 258 Iquitos
Fully refundableReserve now, pay when you stay
The price is £98 per night from 21 Jul to 22 Jul
£98
21 Jul - 22 Jul
8.8/10 Excellent! (377 reviews)
"Clean room good location"

Reviewed on 3 Jul 2026

DoubleTree by Hilton Iquitos
El Dorado Classic Hotel

El Dorado Classic Hotel

3 out of 5
Napo 362 Iquitos Loreto
Fully refundableReserve now, pay when you stay
The price is £37 per night from 11 Jul to 12 Jul
£37
11 Jul - 12 Jul
8.2/10 Very good! (139 reviews)
"This was my 3rd one-night stay at the El Dorado Classic. This last visit I stayed on the 4th floor and the suite was basic but very clean and the bed was quite comfortable. There was very hot water , which wasn’t available during previous stays in lower rooms. I did observe that the hot water began ..."

Reviewed on 3 Jul 2026

El Dorado Classic Hotel
Hotel de Turistas Iquitos

Hotel de Turistas Iquitos

3 out of 5
Napo Iquitos Loreto
Fully refundableReserve now, pay when you stay
The price is £46 per night from 6 Aug to 7 Aug
£46
6 Aug - 7 Aug
8.8/10 Excellent! (49 reviews)
"Beautiful room, amazing view from the rooftop bar. Very helpful staff and easy to walk to amenities, including Anaconda market."

Reviewed on 24 Jun 2026

Hotel de Turistas Iquitos
See all 221 properties in Loreto Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Cruz travel package cost?
From just , you can handcraft your own Santa Cruz travel package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Santa Cruz travel package. If you booked in the last 24 hours, you may be eligible for a refund. If your booking is older, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal to learn more.
How do I get a cheap travel package to Santa Cruz?
If you love amazing deals, bundle your bookings into a Santa Cruz holiday package. Whether you're searching for flights, hotels, tours or rental cars, you can book them all in one place. You'll have lots of choice at your fingertips too. Expedia has more than 550 air carriers and 1,000,000 hotels around the world to choose from. Fly with who you want, find a room where you like and save precious money — now that's the perfect escape!
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Yes. Expedia has teamed up with online lender Klarna to help you easily pay for your trip in manageable instalments. Simply click on the payment plan best suited to your needs during the checkout process and take the stress out of budgeting for your next trip. Remember to bundle your accommodation, flights and activities with Expedia to get the biggest bang for your buck. Browse our flexible payment options below:

  • Pay monthly holidays: If paying small amounts each month sounds right for you, Klarna can help. Paying in convenient monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your trip across multiple transactions.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the full total upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan with Klarna.

What are the top hotels in Santa Cruz?
Hotel Rio Huallaga is one of Santa Cruz's most well-known hotels. Lock in a room here and you can snooze soundly knowing you're in excellent hands.
How far in advance should I book my Santa Cruz holiday?
It's tricky picking the best time for airfares, but we usually say the earlier, the better. Many international flights on Expedia become available up to a year in advance. If you're booking at the last minute, don't despair. Bargain prices appear from time to time just weeks before departure dates.
What does an Expedia Santa Cruz travel package include?
That depends on what you're looking for. If you're travelling solo, you might decide to bundle flights and hotels. Taking the whole family to Santa Cruz? A travel package that includes rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to tailor your travel package.
What should I know before booking a Santa Cruz travel package?
Get set to save with an Expedia travel package. Bundle your airfares, rental cars and hotels and land fabulous discounts. You're not limited to hotels, however. We have beachside condos, mountain cabins and everything in between!
Can I choose my airline with a Santa Cruz Expedia travel package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our travel packages give you the flexibility to pick from available flight, hotel or activity options that suit you.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.