Title: Hotels in Santa Cruz Mixtepec - Best Santa Cruz Mixtepec Hotels from £17 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Cruz Mixtepec](https://expedia.co.uk/Santa-Cruz-Mixtepec-Holiday-Rentals.d553248635640628853.Travel-Guide-HolidayRentals)[Santa Cruz Mixtepec Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Mixtepec.d553248635640628853.Car-Hire-Guide)[Santa Cruz Mixtepec Holidays](https://expedia.co.uk/Santa-Cruz-Mixtepec.d553248635640628853.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Cruz Mixtepec from £17 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Cruz Mixtepec Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz+Mixtepec%2C+Oaxaca%2C+Mexico®ionId=553248635640628853&latLong=16.789997%2C-96.905339&adults=2&startDate=2026-01-07&d1=2026-01-07&endDate=2026-01-09&d2=2026-01-09&lodging=APARTMENT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz+Mixtepec%2C+Oaxaca%2C+Mexico®ionId=553248635640628853&latLong=16.789997%2C-96.905339&adults=2&startDate=2026-01-07&d1=2026-01-07&endDate=2026-01-09&d2=2026-01-09&amenities=PETS) ## Check prices for these dates Tonight [24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640628853&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [25 Dec - 26 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640628853&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640628853&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640628853&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz Mixtepec hotels ![Living area](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928478/f3419f9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Quadruple Room, 2 Double Beds | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928478/91e06665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Quadruple Room | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928478/bda8beec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 1 Double Bed | Bathroom | Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928478/6ab616c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LA PATRONA HOSTAL [](https://www.expedia.co.uk/Oaxaca-Hotels-LA-PATRONA-HOSTAL.h113928478.Hotel-Information) Santa Cruz Xoxocotlán 10/10 Exceptional (1) £17 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Oaxaca-Hotels-LA-PATRONA-HOSTAL.h113928478.Hotel-Information) ![Executive Suite, 1 King Bed | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/20000000/19120000/19114500/19114426/d5d7f7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/20000000/19120000/19114500/19114426/bc9d1d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/20000000/19120000/19114500/19114426/e1da450b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed | Terrace/patio](https://images.trvl-media.com/lodging/20000000/19120000/19114500/19114426/afce238c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maria Ines Hotel Suite [](https://www.expedia.co.uk/Oaxaca-Hotels-Maria-Ines-Hotel-Suite.h19114426.Hotel-Information) San Agustín de las Juntas 9.4/10 Exceptional (392) "Great service and friendly staff. Clean room close to the airport." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey [](https://www.expedia.co.uk/Oaxaca-Hotels-Maria-Ines-Hotel-Suite.h19114426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/53e2a48d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/046b9663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Double Room | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/5d690b5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/aaae37e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Puerta del Cielo [](https://www.expedia.co.uk/Oaxaca-Hotels-Motel-Puerta-Del-Cielo.h39211936.Hotel-Information) San Agustín de las Juntas 8.6/10 Excellent (4) "Good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Manuel £64 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Oaxaca-Hotels-Motel-Puerta-Del-Cielo.h39211936.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/37000000/36700000/36699000/36698970/d4f10f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/37000000/36700000/36699000/36698970/da1e9386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/37000000/36700000/36699000/36698970/987cd52f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36700000/36699000/36698970/f612e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Guivá Aeropuerto [](https://www.expedia.co.uk/Oaxaca-Hotels-Hotel-Guiva-Aeropuerto.h36698970.Hotel-Information) San Agustín de las Juntas 7.4/10 Good (32) "Staff was friendly and helpful. Check on and out was easy and quick. Room was clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) fernando £71 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Oaxaca-Hotels-Hotel-Guiva-Aeropuerto.h36698970.Hotel-Information) ![Standard Double Room | Free WiFi](https://images.trvl-media.com/lodging/124000000/123610000/123601500/123601425/e0c59e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Free WiFi](https://images.trvl-media.com/lodging/124000000/123610000/123601500/123601425/34e27959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony, City View | Private kitchen](https://images.trvl-media.com/lodging/124000000/123610000/123601500/123601425/977d32e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room, Balcony, City View | Bathroom | Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/124000000/123610000/123601500/123601425/b625d2f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel boutique Casa Gopar [](https://www.expedia.co.uk/Ocotlan-De-Morelos-Hotels-Hotel-Boutique-Casa-Gopar.h123601425.Hotel-Information) Ocotlán de Morelos £36 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Ocotlan-De-Morelos-Hotels-Hotel-Boutique-Casa-Gopar.h123601425.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103820000/103813400/103813375/f9b3d0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | View from room](https://images.trvl-media.com/lodging/104000000/103820000/103813400/103813375/bced2e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/104000000/103820000/103813400/103813375/b6878a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | 1 bedroom, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/104000000/103820000/103813400/103813375/524fd0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villas Horizonte Oaxaca [](https://www.expedia.co.uk/Santa-Maria-Coyotepec-Hotels-Villas-Horizonte-Oaxaca.h103813375.Hotel-Information) Santa María Coyotepec 6.8/10 (3) "Rooms are nice and clean, they gave me a room without air conditioned but I told them I booked a room with AC and they gave me another room. The hotel is out of downtown, no noise, streets are not paved in that area. It is a good chooce If you don’t want to expend too much money. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lourdes £38 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Santa-Maria-Coyotepec-Hotels-Villas-Horizonte-Oaxaca.h103813375.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/47000000/46340000/46331800/46331727/fc660c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/47000000/46340000/46331800/46331727/93294a78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/47000000/46340000/46331800/46331727/994dbc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Shower, towels, soap](https://images.trvl-media.com/lodging/47000000/46340000/46331800/46331727/a48f1748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hotel Rey David, Oaxaca [](https://www.expedia.co.uk/Ocotlan-De-Morelos-Hotels-Hotel-Rey-David.h46331727.Hotel-Information) Ocotlán de Morelos 4.4/10 (32) "No AC, Fans, Poor Place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier £19 includes taxes & fees 26 Dec - 27 Dec [](https://www.expedia.co.uk/Ocotlan-De-Morelos-Hotels-Hotel-Rey-David.h46331727.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/28000000/27160000/27156300/27156240/f3783978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Hot Tub | Bathroom | Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/28000000/27160000/27156300/27156240/1fa2211e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Hot Tub | Free WiFi](https://images.trvl-media.com/lodging/28000000/27160000/27156300/27156240/faeeb1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Hot Tub | Free WiFi](https://images.trvl-media.com/lodging/28000000/27160000/27156300/27156240/0b485bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Las Maravillas [](https://www.expedia.co.uk/Oaxaca-Hotels-Motel-Las-Maravillas.h27156240.Hotel-Information) Santa Cruz Xoxocotlán 3.0/10 (4) "Dirty rooms, broken washrooms, terrible linen and towels. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Rajan £76 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Oaxaca-Hotels-Motel-Las-Maravillas.h27156240.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08®ionId=553248635640628853&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Mixtepec-Hotels.d553248635640628853.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Mixtepec-Hotels.d553248635640628853.Travel-Guide-Hotels) ## Top Santa Cruz Mixtepec Hotel Reviews ![Maria Ines Hotel Suite](https://images.trvl-media.com/lodging/20000000/19120000/19114500/19114426/d5d7f7f0_y.jpg) ### Maria Ines Hotel Suite 10/10 Excellent "Great service and friendly staff. Clean room close to the airport." [](https://expedia.co.uk/Oaxaca-Hotels-Maria-Ines-Hotel-Suite.h19114426.Hotel-Information) ![Motel Puerta del Cielo](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/53e2a48d_y.jpg) ### Motel Puerta del Cielo 10/10 Excellent "Good " [](https://expedia.co.uk/Oaxaca-Hotels-Motel-Puerta-Del-Cielo.h39211936.Hotel-Information) ![Hotel Guivá Aeropuerto](https://images.trvl-media.com/lodging/37000000/36700000/36699000/36698970/d4f10f9d_y.jpg) ### Hotel Guivá Aeropuerto 10/10 Excellent "The room was clean and tidy, the staff friendly. If you want an easy place to stay before flying out of Oaxaca, this airport hotel is just 5 minutes away. The staff will order a taxi for you. " [](https://expedia.co.uk/Oaxaca-Hotels-Hotel-Guiva-Aeropuerto.h36698970.Hotel-Information) ![Villas Horizonte Oaxaca](https://images.trvl-media.com/lodging/104000000/103820000/103813400/103813375/f9b3d0b4_y.jpg) ### Villas Horizonte Oaxaca 8/10 Good "Rooms are nice and clean, they gave me a room without air conditioned but I told them I booked a room with AC and they gave me another room. The hotel is out of downtown, no noise, streets are not paved in that area. It is a good chooce If you don’t want to expend too much money. " [](https://expedia.co.uk/Santa-Maria-Coyotepec-Hotels-Villas-Horizonte-Oaxaca.h103813375.Hotel-Information) ## More cheap stays in Santa Cruz Mixtepec ![LA PATRONA HOSTAL](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928478/f3419f9f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### LA PATRONA HOSTAL Corregidora Santa Elena Oaxaca OAX £17 4 Jan - 5 Jan 2026 includes taxes & fees [](https://expedia.co.uk/Oaxaca-Hotels-LA-PATRONA-HOSTAL.h113928478.Hotel-Information) ![OYO Hotel Rey David, Oaxaca](https://images.trvl-media.com/lodging/47000000/46340000/46331800/46331727/fc660c33_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### OYO Hotel Rey David, Oaxaca 16 de Septiembre 248 Ocotlán de Morelos OAX £19 26 Dec - 27 Dec includes taxes & fees 4.2/10 (32 reviews) [](https://expedia.co.uk/Ocotlan-De-Morelos-Hotels-Hotel-Rey-David.h46331727.Hotel-Information) ![Motel Puerta del Cielo](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/53e2a48d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Puerta del Cielo Av. Símbolos 917 Oaxaca OAX £64 4 Jan - 5 Jan 2026 includes taxes & fees 8.6/10 Excellent! (4 reviews) [](https://expedia.co.uk/Oaxaca-Hotels-Motel-Puerta-Del-Cielo.h39211936.Hotel-Information) ![Motel Las Maravillas](https://images.trvl-media.com/lodging/28000000/27160000/27156300/27156240/f3783978_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Las Maravillas Blvd. Benito Juarez García 1120 Oaxaca OAX £76 4 Jan - 5 Jan 2026 includes taxes & fees 3/10 (4 reviews) [](https://expedia.co.uk/Oaxaca-Hotels-Motel-Las-Maravillas.h27156240.Hotel-Information) ![Espectacular y Moderno Apartamento, con Jacuzzi!!! ](https://images.trvl-media.com/lodging/109000000/108730000/108720600/108720591/c01c41d6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Espectacular y Moderno Apartamento, con Jacuzzi!!! Santa Cruz Xoxocotlán OAX £143 25 Dec - 26 Dec includes taxes & fees [](https://expedia.co.uk/Oaxaca-Hotels-Espectacular-Y-Moderno-Apartamento.h108720591.Hotel-Information) ![Hotel Senda del Ángel](https://images.trvl-media.com/lodging/107000000/106860000/106854700/106854609/w1080h718x0y12-3bef88a1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Senda del Ángel Camino Real San Bartolo Coyotepec OAX [Get rates](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=106854609&PinnedHotelID=106854609&HadPinnedHotel=true®ionId=553248635640628853) [](https://expedia.co.uk/San-Bartolo-Coyotepec-Hotels-Hotel-Senda-Del-Angel.h106854609.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa Cruz Mixtepec? ### What are some of the best holiday rentals that Santa Cruz Mixtepec has to offer? ### If I need to cancel my hotel reservation in Santa Cruz Mixtepec, will I receive a refund? ### What's it like to stay in Santa Cruz Mixtepec? 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