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Our top choices for Santa Cruz luxury hotels

1. Hotel Vendimia Parador

Hotel Vendimia Parador
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (90 reviews)
"A lovely hotel run by a lovely family!"
United States
Amihai
The price is £87
26 Nov - 27 Nov
Hotel Vendimia Parador

2. Casa Calfu

Casa Calfu
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (67 reviews)
"Charming place ! "
France
Ruxandra
The price is £61
3 Nov - 4 Nov
Casa Calfu

3. Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (147 reviews)
"Loved the rustic hotel and Mauricio and Carla are awesome hosts! Great location and an amazing place to stay. Highly recommended. "
United States
Orlando
The price is £53
3 Nov - 4 Nov
Hotel Boutique Vendimia Premium

4. TerraViña

TerraViña
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (220 reviews)
"Great location, friendly staff ."
United Kingdom
DARREN
The price is £224
3 Nov - 4 Nov
TerraViña

5. Santa Cruz Plaza

Santa Cruz Plaza
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (376 reviews)
"Unfortunately our room faced the plaza and loud band until almost midnight! Also at 3 am we were awakened by loud tapping noise that lasted about 20 minutes"
United States
Hector
The price is £88
16 Nov - 17 Nov
Santa Cruz Plaza

6. Hotel Cava Colchagua

Hotel Cava Colchagua
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (178 reviews)
"Interesting and beautiful place to stay. Barrel rooms are comfortable. Staff are very pleasant and accomodating. Food at the restaurant was fantastic. Shower was not the best."
Canada
Anonymous traveller
The price is £99
18 Nov - 19 Nov
Hotel Cava Colchagua

7. Hostal Vida 2000

Hostal Vida 2000
2.5 star property
Santa Cruz
6.6 out of 10, (4 reviews)
"Simple clean place with wonderful hosts that were very accommodating. Breakfast was set up beautifully with plenty of food."
United States
Kati
The price is £24
3 Nov - 4 Nov
Hostal Vida 2000

8. Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (11 reviews)
"Cute lodge with friendly staff that helps you to your cozy room- sets up your hot tub and brings an amazing basket for breakfast! Can’t wait to go back "
United States
Jonathan
The price is £135
3 Nov - 4 Nov
Colchagua Tiny Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Cruz Hotel Reviews

Frequently asked questions

Which area of Santa Cruz, O'Higgins Region, Chile is best to stay in for luxury hotels?
The Colchagua Valley wine-country outskirts offer the most luxurious stays in Santa Cruz, particularly around Apalta and the vineyard areas west or southwest of town. This region is home to some of the most upscale properties, including the renowned Clos Apalta Residence, providing a truly indulgent experience amidst stunning vineyard landscapes.

For those prioritising convenience and accessibility, the Santa Cruz town centre, particularly around Plaza de Armas, is an excellent choice. Here, you'll find the main upscale full-service hotel in town, Hotel Santa Cruz, which places you within easy reach of restaurants, local services, and tour departure points.

If a boutique wine-lodge atmosphere appeals to you, the various vineyard properties scattered throughout the Colchagua Valley, close to Santa Cruz, provide an intimate and authentic experience.
How much does a luxury hotel in Santa Cruz cost?
Luxury hotel prices in Santa Cruz vary, but you can find a great deal from £24 on Expedia. To find the best prices on luxury stays, be flexible with your dates. Typically, off-peak and mid-week stays are cheaper. Sort your search results by "Price: low to high" to see our lowest rates.
What are the top-rated luxury hotels in Santa Cruz?
Hotel Cava Colchagua, a luxurious 4-star retreat, is celebrated by guests with a superb 9.0 rating and offers an exclusive experience for those who appreciate the finer things in life. This magnificent hotel boasts its own onsite winery, providing guests with the unique opportunity to embark on private tours and indulge in exquisite tasting room experiences, all while surrounded by picturesque vineyards. Each room is designed for ultimate comfort, featuring premium bedding and air conditioning, ensuring a tranquil and restful stay. For those who value convenience, room service is readily available, allowing you to savour delicious meals in the privacy of your own elegant space.

For couples seeking a truly pampering escape, the Santa Cruz Plaza, another splendid 4-star hotel with an impressive 8.8 guest rating, presents an array of indulgent amenities. Its full-service spa is a haven of relaxation, offering everything from invigorating body scrubs and wraps to soothing massages and hydrotherapy treatments. You can also unwind in the sauna or steam room, or perhaps treat yourselves to a rejuvenating facial. The hotel thoughtfully provides designer toiletries, adding an extra touch of luxury to your stay.
Which luxury hotels in Santa Cruz are good for families?
The Hotel Cava Colchagua, a splendid 4-star establishment with a superb guest rating of 9.0, truly excels in offering an exceptional family experience. Imagine indulging in private winery tours and delightful tasting room experiences right on site, surrounded by picturesque vineyards. The hotel also ensures your comfort with premium bedding and air conditioning, while convenient room service means you can relax and enjoy gourmet meals together without leaving your spacious accommodation. Guests consistently praise the attentive and extremely helpful staff, the fantastic food, and the great rooms.

For those seeking an equally luxurious yet distinct family stay, the Santa Cruz Plaza, another magnificent 4-star hotel with an impressive 8.8 guest rating, offers an array of indulgent amenities. Here, you can unwind in style with a swim-up bar, great for family fun in the sun, and pamper yourselves with designer toiletries. The full-service spa is a haven of relaxation, offering an extensive menu of treatments including body treatments, massages, body wraps, body scrubs, hydrotherapy, and facial treatments, all available with advance notice. The spa also boasts a sauna and steam room for ultimate rejuvenation.
What luxury activities and experiences are there in Santa Cruz, O'Higgins Region, Chile?
Santa Cruz, located in Chile's O'Higgins Region, is renowned for its luxurious wine experiences, particularly exclusive vineyard tours and premium tastings. The Colchagua Valley, a jewel in its crown, beckons with high-end dining and bespoke adventures, promising quality and convenience for travellers.

For couples seeking a romantic escape, Santa Cruz offers an array of intimate experiences. Imagine private wine tastings and cellar tours at prestigious estates like Viu Manent and Lapostolle Clos Apalta, followed by gourmet food-and-wine pairings under the stars. Horseback riding through sun-drenched vineyards or indulging in a spa-style relaxation at a boutique hotel with breathtaking vineyard views truly sets the scene for an unforgettable getaway.

Adventure-seekers will find plenty to excite them amidst the stunning landscapes of Santa Cruz. Exclusive private tours of the Colchagua Wine Route, often with premium transport and hotel pickup, provide a seamless way to explore. Beyond wine, scenic outdoor activities such as hiking, biking, and stargazing around Cerro Chamán offer a thrilling contrast, blending luxury with the thrill of discovery.

Wine connoisseurs will be in their element, with Santa Cruz offering unparalleled access to some of Chile's finest wineries. Private tastings at Montes and Maquis, alongside boutique winery lunches, provide a deep dive into the region's viticultural excellence. The option to combine these with cultural luxury add-ons, such as visits to the Colchagua Museum or a ride on the historic Tren del Vino, ensures a truly curated and enriching experience.
What are the best luxury hotels in Santa Cruz with a pool?
The Hotel Cava Colchagua, a 4-star gem with a superb 9.0 guest rating, offers an exquisite experience for those who appreciate the finer things in life. Guests can indulge in private winery tours and tastings right on-site, surrounded by the hotel's own vineyard. After a delightful day, relax in rooms featuring premium bedding and air conditioning, with the convenience of room service. The hotel boasts an outdoor pool that is open 24 hours, great for a refreshing dip at any time.

Another excellent choice is the 4-star Santa Cruz Plaza, rated 8.8 by travellers, which provides a luxurious escape with an outdoor pool featuring a swim-up bar – ideal for enjoying a refreshing drink without leaving the water. This hotel truly pampers its guests with a full-service spa, offering an array of body treatments, wraps, and scrubs, as well as invigorating hydrotherapy and facial treatments. You'll find designer toiletries in your room, and can unwind in the sauna or steam room.
Are there any top luxury hotels near Laura Hartwig Winery?
Yes. For those seeking a luxurious escape near Laura Hartwig Winery, Hotel Cava Colchagua and Santa Cruz Plaza are excellent choices.

Hotel Cava Colchagua, a splendid 4-star establishment with a superb guest rating of 9.0, offers an unparalleled experience for wine enthusiasts. Imagine indulging in private winery tours and delightful tastings right on-site. The hotel boasts its own vineyard, ensuring a truly immersive viticultural journey. You'll also appreciate the premium bedding for a restful night's sleep and air conditioning for ultimate comfort, with room service readily available for your convenience. Guests consistently rave about the attentive and extremely helpful staff, fantastic food, and great rooms.

Meanwhile, the 4-star Santa Cruz Plaza, rated 8.8 by travellers, provides a more extensive range of pampering facilities. This hotel is great for couples looking to unwind and rejuvenate. Picture yourself sipping a refreshing drink at the swim-up bar or indulging in a full-service spa experience that includes body treatments, body wraps, body scrubs, and facial treatments. The spa also features a sauna, steam room, and hydrotherapy treatments, all available daily with advance notice for your ultimate relaxation. You'll find designer toiletries in your room, adding a touch of elegance to your stay.
Which luxury hotels in Santa Cruz are near Santiago (SCL-Arturo Merino Benitez)?
The Hotel Cava Colchagua, a splendid 4-star establishment with a superb guest rating of 9.0, truly embodies the spirit of luxury for couples with a passion for fine wines. Guests can indulge in the great experience of private winery tours and savour exquisite vintages in the hotel's dedicated tasting room, all conveniently located right on site amidst beautiful vineyards. Each room is designed for ultimate comfort, featuring premium bedding and air conditioning, ensuring a restful stay, and for those moments of indulgence, room service is readily available. Customers consistently praise the attentive and extremely helpful staff, fantastic food, and great rooms.

Another excellent choice is the 4-star Santa Cruz Plaza, which boasts a very good guest rating of 8.8 and offers an array of pampering amenities. This hotel is a haven for relaxation, featuring a full-service spa where you can unwind with body treatments, massages, and hydrotherapy treatments. The spa also includes a sauna and steam room, great for rejuvenating after a day of exploring. For an extra touch of luxury, guests will find designer toiletries, and the option to enjoy refreshing drinks at the swim-up bar.
Can I cancel my luxury hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right luxury hotel in Santa Cruz for you.
How can I save on a luxury hotel in Santa Cruz with Expedia?
There are plenty of ways to save on a luxury hotel in Santa Cruz. Join One Key™, our free travel rewards programme, to unlock instant discounts with Member Prices across a range of premium hotels. Typically, booking in advance will help you save on your luxury hotel stay. If you're feeling spontaneous, be sure to check for last-minute deals.
Is it cheaper to book a luxury Santa Cruz hotel and flights as a package?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. *Savings vary and are not available on all flight and hotel bookings.