A vineyard with rows of grapevines.

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Check availability on Santa Cruz Luxury Hotels

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Santa Cruz luxury hotels

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.
A restaurant interior with wooden tables and chairs, a sign reading 'DECAVAS RESTAURANT', and large windows offering a view of greenery.
A rustic wooden structure with a bench and a table, suggesting a seating area.
A large bed with a headboard, two bedside tables, a small table with a lamp, and a trash bin.

1. Hotel Cava Colchagua

Hotel Cava Colchagua
Santa Cruz
£104
24 Sept - 25 Sept
Hotel Cava Colchagua
A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.
A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.
A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.
A spa area with a hot tub, candles, and towels on a wooden table.

2. Santa Cruz Plaza

Santa Cruz Plaza
Santa Cruz
£78
27 Sept - 28 Sept
Santa Cruz Plaza
A modern bathroom with a large window, a curved bathtub, and a view of a valley.
A modern bedroom with a large bed, a sofa, a small table, and a desk. The room has large windows offering a view of mountains and trees.
A wooden deck with a pool, lounge chairs, and umbrellas overlooking a lake with mountains in the background.
A bedroom with a large bed, a desk, and a chair, with a view of mountains and a lake.

3. Vik Chile

Vik Chile
San Vicente
  • Relax amid wine country elegance at this San Vicente luxury hotel with 2 restaurants and a winery on-site.
£575
27 Sept - 28 Sept
Vik Chile
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Top Santa Cruz Hotel Reviews

TerraViña

TerraViña

10/10 Excellent
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."
andy 2-night trip
Posted 2 months ago
TerraViña

Frequently asked questions

Are you looking for a luxury hotel for your Santa Cruz holiday?
During your visit, you might want to enjoy the tours which Santa Cruz is known for.
What's the best high-end hotel in Santa Cruz?
Vibo Wine Lodge is a luxury lodge with a winery and private balconies, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Santa Cruz?
Planning for the weather is an important factor for making your trip to Santa Cruz a success, especially when you're splurging. The hottest months are usually January and February, with an average temperature of 21°C, while the coldest months are July and August, with an average of 10°C. Average annual precipitation for Santa Cruz is 743 mm.
What's there to see and do in Santa Cruz?
Experience all that Santa Cruz has to offer when you visit Museo de Colchagua, Laura Hartwig Winery and Casino Colchagua. If you have some spare time during your trip, you might want to check out Lapostolle Clos Apalta Winery and Millahue Valley.